JP2001072677A5 - - Google Patents
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- Publication number
- JP2001072677A5 JP2001072677A5 JP1998101058A JP10105898A JP2001072677A5 JP 2001072677 A5 JP2001072677 A5 JP 2001072677A5 JP 1998101058 A JP1998101058 A JP 1998101058A JP 10105898 A JP10105898 A JP 10105898A JP 2001072677 A5 JP2001072677 A5 JP 2001072677A5
- Authority
- JP
- Japan
- Prior art keywords
- less
- paroxetine
- isopropyl alcohol
- drying
- paroxetine hydrochloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 36
- AHOUBRCZNHFOSL-UHFFFAOYSA-N 3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine Chemical compound C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 claims description 31
- 229960005183 paroxetine hydrochloride Drugs 0.000 claims description 13
- 238000001035 drying Methods 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 5
- 229960002296 paroxetine Drugs 0.000 claims description 5
- -1 paroxetine compound Chemical class 0.000 claims description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 2
- 229910000041 hydrogen chloride Inorganic materials 0.000 claims description 2
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- AHOUBRCZNHFOSL-YOEHRIQHSA-N (+)-Casbol Chemical compound C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-YOEHRIQHSA-N 0.000 claims 1
Priority Applications (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10105898A JP3796351B2 (ja) | 1998-04-13 | 1998-04-13 | パロキセチン塩酸塩無水和物の乾燥方法 |
| DE69909207T DE69909207T2 (de) | 1998-04-13 | 1999-04-12 | Verfahren zur trocknung von paroxetinhydrochlorid |
| AU52656/99A AU730652B2 (en) | 1998-04-13 | 1999-04-12 | Method for drying anhydrous paroxetine hydrochloride |
| PCT/JP1999/001914 WO1999052902A1 (en) | 1998-04-13 | 1999-04-12 | Method for drying anhydrous paroxetine hydrochloride |
| AT99945685T ATE244237T1 (de) | 1998-04-13 | 1999-04-12 | Verfahren zur trocknung von paroxetinhydrochlorid |
| US09/445,598 US6541637B1 (en) | 1998-04-13 | 1999-04-12 | Method for drying anhydrous paroxetine hydrochloride |
| EP99945685A EP0990655B1 (en) | 1998-04-13 | 1999-04-12 | Method for drying anhydrous paroxetine hydrochloride |
| CA002294716A CA2294716C (en) | 1998-04-13 | 1999-04-12 | Method for drying anhydrous paroxetine hydrochloride |
| PT99945685T PT990655E (pt) | 1998-04-13 | 1999-04-12 | Metodo de secagem de cloridrato de paroxetina anidro |
| ES99945685T ES2199592T3 (es) | 1998-04-13 | 1999-04-12 | Procedimiento para secar hidrocloruro de paroxetina anhidro. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10105898A JP3796351B2 (ja) | 1998-04-13 | 1998-04-13 | パロキセチン塩酸塩無水和物の乾燥方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001072677A JP2001072677A (ja) | 2001-03-21 |
| JP2001072677A5 true JP2001072677A5 (enExample) | 2005-02-03 |
| JP3796351B2 JP3796351B2 (ja) | 2006-07-12 |
Family
ID=14290525
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10105898A Expired - Fee Related JP3796351B2 (ja) | 1998-04-13 | 1998-04-13 | パロキセチン塩酸塩無水和物の乾燥方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6541637B1 (enExample) |
| EP (1) | EP0990655B1 (enExample) |
| JP (1) | JP3796351B2 (enExample) |
| AT (1) | ATE244237T1 (enExample) |
| AU (1) | AU730652B2 (enExample) |
| CA (1) | CA2294716C (enExample) |
| DE (1) | DE69909207T2 (enExample) |
| ES (1) | ES2199592T3 (enExample) |
| PT (1) | PT990655E (enExample) |
| WO (1) | WO1999052902A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1394160A1 (en) | 1996-06-13 | 2004-03-03 | SUMIKA FINE CHEMICALS Co., Ltd. | Process for preparing crystalline paroxetin hydrochloride |
| HUP0105466A3 (en) * | 1998-08-07 | 2002-11-28 | Smithkline Beecham Plc | Process for the preparation of a non-crystalline anhydrate form of paroxetine hydrochloride and pharmaceutical compositions containing them |
| GB9826176D0 (en) * | 1998-11-28 | 1999-01-20 | Smithkline Beecham Plc | Novel process |
| US20080033050A1 (en) | 2006-08-04 | 2008-02-07 | Richards Patricia Allison Tewe | Method of treating thermoregulatory disfunction with paroxetine |
| US9138430B2 (en) * | 2007-12-27 | 2015-09-22 | Mylan Specialty L.P. | Formulation and method for the release of paroxetine in the large intestine |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR001982A1 (es) | 1995-02-06 | 1998-01-07 | Smithkline Beecham Plc | Clorhidrato de paroxetina anhidratado, y procedimiento para su preparacion |
| US5856493A (en) * | 1995-02-06 | 1999-01-05 | Smithkline Beecham Corporation | Process for making novel form of paroxeting hydrochloride anhydrate |
| JP3819532B2 (ja) | 1996-06-13 | 2006-09-13 | 住友化学株式会社 | ピペリジン誘導体およびその製造方法 |
| EP1394160A1 (en) * | 1996-06-13 | 2004-03-03 | SUMIKA FINE CHEMICALS Co., Ltd. | Process for preparing crystalline paroxetin hydrochloride |
| HUP0105466A3 (en) | 1998-08-07 | 2002-11-28 | Smithkline Beecham Plc | Process for the preparation of a non-crystalline anhydrate form of paroxetine hydrochloride and pharmaceutical compositions containing them |
-
1998
- 1998-04-13 JP JP10105898A patent/JP3796351B2/ja not_active Expired - Fee Related
-
1999
- 1999-04-12 AU AU52656/99A patent/AU730652B2/en not_active Ceased
- 1999-04-12 WO PCT/JP1999/001914 patent/WO1999052902A1/ja not_active Ceased
- 1999-04-12 CA CA002294716A patent/CA2294716C/en not_active Expired - Fee Related
- 1999-04-12 EP EP99945685A patent/EP0990655B1/en not_active Expired - Lifetime
- 1999-04-12 PT PT99945685T patent/PT990655E/pt unknown
- 1999-04-12 ES ES99945685T patent/ES2199592T3/es not_active Expired - Lifetime
- 1999-04-12 US US09/445,598 patent/US6541637B1/en not_active Expired - Fee Related
- 1999-04-12 DE DE69909207T patent/DE69909207T2/de not_active Expired - Lifetime
- 1999-04-12 AT AT99945685T patent/ATE244237T1/de active
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