JP2593295B2 - 組換え体表面タンパク質を持つウイルス - Google Patents
組換え体表面タンパク質を持つウイルスInfo
- Publication number
- JP2593295B2 JP2593295B2 JP58500629A JP50062983A JP2593295B2 JP 2593295 B2 JP2593295 B2 JP 2593295B2 JP 58500629 A JP58500629 A JP 58500629A JP 50062983 A JP50062983 A JP 50062983A JP 2593295 B2 JP2593295 B2 JP 2593295B2
- Authority
- JP
- Japan
- Prior art keywords
- virus
- protein
- segment
- dna
- base sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2795/00—Bacteriophages
- C12N2795/00011—Details
- C12N2795/10011—Details dsDNA Bacteriophages
- C12N2795/10311—Siphoviridae
- C12N2795/10341—Use of virus, viral particle or viral elements as a vector
- C12N2795/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3384164 | 1982-01-11 | ||
| US06/338,416 US4593002A (en) | 1982-01-11 | 1982-01-11 | Viruses with recombinant surface proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS59500042A JPS59500042A (ja) | 1984-01-12 |
| JP2593295B2 true JP2593295B2 (ja) | 1997-03-26 |
Family
ID=23324738
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58500629A Expired - Lifetime JP2593295B2 (ja) | 1982-01-11 | 1983-01-07 | 組換え体表面タンパク質を持つウイルス |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4593002A (enExample) |
| EP (1) | EP0098299B1 (enExample) |
| JP (1) | JP2593295B2 (enExample) |
| AU (1) | AU562548B2 (enExample) |
| CA (1) | CA1211060A (enExample) |
| DE (1) | DE3367851D1 (enExample) |
| ES (1) | ES518870A0 (enExample) |
| FI (1) | FI833174A7 (enExample) |
| GB (1) | GB2125065B (enExample) |
| GR (1) | GR77173B (enExample) |
| IT (1) | IT1164858B (enExample) |
| NO (1) | NO833205L (enExample) |
| NZ (1) | NZ202954A (enExample) |
| PT (1) | PT76079B (enExample) |
| WO (1) | WO1983002393A1 (enExample) |
| ZA (1) | ZA8358B (enExample) |
Families Citing this family (99)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0117767A1 (en) * | 1983-01-07 | 1984-09-05 | Mgi Pharma, Inc. | Production of parvovirus subunit vaccines |
| IL70704A0 (en) * | 1983-01-19 | 1984-04-30 | Amgen | Methods and materials for development of parvovirus vaccines |
| US5338674A (en) * | 1983-02-25 | 1994-08-16 | Wright Stephen E | Process for producing a vaccine for a pathogenic RNA virus and product thereof |
| NZ209308A (en) * | 1983-08-30 | 1991-08-27 | Genentech Inc | Vaccine against hsv involving a truncated membrane-free derivative of a membrane-bound protein |
| US7264817B1 (en) | 1983-08-30 | 2007-09-04 | Genentech, Inc. | Immunogenic composition based on a truncated derivative of a membrane bound protein and process for making it |
| US5288641A (en) * | 1984-06-04 | 1994-02-22 | Arch Development Corporation | Herpes Simplex virus as a vector |
| CA1282721C (en) * | 1984-06-04 | 1991-04-09 | Bernard Roizman | Herpes simplex virus as a vector |
| US4722840A (en) * | 1984-09-12 | 1988-02-02 | Chiron Corporation | Hybrid particle immunogens |
| IL76751A (en) * | 1984-11-01 | 1991-04-15 | American Home Prod | Method and oral vaccines against infectious organisms using live,recombinant adenovirus for the production of antibodies |
| US5643579A (en) * | 1984-11-01 | 1997-07-01 | American Home Products Corporation | Oral vaccines |
| FR2573436B1 (fr) * | 1984-11-20 | 1989-02-17 | Pasteur Institut | Adn recombinant comportant une sequence nucleotidique codant pour un polypeptide determine sous le controle d'un promoteur d'adenovirus, vecteurs contenant cet adn recombinant, cellules eucaryotes transformees par cet adn recombinant, produits d'excretion de ces cellules transformees et leurs applications, notamment a la constitution de vaccins |
| US6696420B1 (en) | 1984-11-20 | 2004-02-24 | Institut Pasteur | Adenoviral vector with a deletion in the E1A coding region expressing a hetorologous protein |
| IL78775A (en) * | 1985-05-15 | 1992-06-21 | Biotech Australia Pty Ltd | Oral vaccines |
| IL79880A0 (en) * | 1985-08-29 | 1986-11-30 | Inst Medical W & E Hall | Recombinant virus |
| US5763269A (en) * | 1985-09-06 | 1998-06-09 | Syntro Corporation | Recombinant infectious bovine rhinotrocheitis virus |
| US5310668A (en) * | 1986-06-20 | 1994-05-10 | Merck & Co., Inc. | Varicella-zoster virus as a live recombinant vaccine |
| DE3632038A1 (de) * | 1986-09-20 | 1988-03-31 | Behringwerke Ag | Gewebespezifische virale vektoren auf basis des lpv und ihre verwendung |
| NZ219515A (en) * | 1987-02-10 | 1989-09-27 | Wellcome Found | Fusion proteins comprising influenza virus ha and a nonnatural antigenic epitope |
| ATE114723T1 (de) * | 1987-03-02 | 1994-12-15 | Enzon Lab Inc | Organismus als träger für ''single chain antibody domain (scad)''. |
| EP0658623A3 (en) * | 1987-07-27 | 1995-09-27 | Syntro Corp | Attenuated herpes viruses, herpes viruses that contain foreign DNA encoding an amino acid sequence, and vaccines containing them. |
| US5182211A (en) * | 1987-08-07 | 1993-01-26 | Institut Pasteur | Plasmid vectors encoding a protein of a picornavirus |
| FR2619012B1 (fr) * | 1987-08-07 | 1989-12-22 | Pasteur Institut | Vaccins dont l'epitope caracteristique est incorpore dans une proteine de picornavirus, notamment de poliovirus |
| US5316931A (en) * | 1988-02-26 | 1994-05-31 | Biosource Genetics Corp. | Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes |
| US6284492B1 (en) | 1988-02-26 | 2001-09-04 | Large Scale Biology Corporation | Recombinant animal viral nucleic acids |
| US6054566A (en) * | 1988-02-26 | 2000-04-25 | Biosource Technologies, Inc. | Recombinant animal viral nucleic acids |
| US20030150019A1 (en) * | 1988-02-26 | 2003-08-07 | Large Scale Biology Corporation | Monopartite RNA virus transformation vectors |
| US5037743A (en) * | 1988-08-05 | 1991-08-06 | Zymogenetics, Inc. | BAR1 secretion signal |
| US5223409A (en) * | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| ES2179854T3 (es) * | 1988-12-13 | 2003-02-01 | Harvard College | Materiales aislados de felv prototipos para uso en modelos de enfermedades y vacunas. |
| US5691170A (en) * | 1989-04-18 | 1997-11-25 | Therion Biologics | Generation of hybrid genes and proteins by virus-mediated recombination |
| US7413537B2 (en) * | 1989-09-01 | 2008-08-19 | Dyax Corp. | Directed evolution of disulfide-bonded micro-proteins |
| EP0939121B2 (de) | 1989-09-12 | 2007-12-26 | AHP Manufacturing B.V. | TFN-bindende Proteine |
| US5427908A (en) * | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| US5723286A (en) * | 1990-06-20 | 1998-03-03 | Affymax Technologies N.V. | Peptide library and screening systems |
| US20030064480A1 (en) * | 1990-06-28 | 2003-04-03 | Leander Lauffer | Fusion proteins with immunoglobulin portions, the preparation and use thereof |
| US6172197B1 (en) | 1991-07-10 | 2001-01-09 | Medical Research Council | Methods for producing members of specific binding pairs |
| US7063943B1 (en) | 1990-07-10 | 2006-06-20 | Cambridge Antibody Technology | Methods for producing members of specific binding pairs |
| US6916605B1 (en) | 1990-07-10 | 2005-07-12 | Medical Research Council | Methods for producing members of specific binding pairs |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| AU8740491A (en) * | 1990-09-28 | 1992-04-28 | Protein Engineering Corporation | Proteinaceous anti-dental plaque agents |
| WO1992009690A2 (en) * | 1990-12-03 | 1992-06-11 | Genentech, Inc. | Enrichment method for variant proteins with altered binding properties |
| US5989886A (en) * | 1991-01-02 | 1999-11-23 | The Johns Hopkins University | Method for the inhibition and prevention of viral replication using fusions of a virus protein and a destructive enzyme |
| DE69233769D1 (de) | 1991-03-01 | 2009-09-24 | Dyax Corp | Chimäres Protein mit Mikroprotein mit zwei oder mehr Disulfidbindungen und Ausgestaltungen davon |
| GB9108386D0 (en) * | 1991-04-19 | 1991-06-05 | Agricultural Genetics Co | Modified plant viruses as vectors |
| WO1993000103A1 (en) * | 1991-06-21 | 1993-01-07 | The Wistar Institute Of Anatomy And Biology | Chimeric envelope proteins for viral targeting |
| WO1993002202A1 (en) * | 1991-07-19 | 1993-02-04 | Syngene, Inc. | Compositions and methods for reproducing positive diagnostic indications |
| US5270170A (en) * | 1991-10-16 | 1993-12-14 | Affymax Technologies N.V. | Peptide library and screening method |
| US5733731A (en) * | 1991-10-16 | 1998-03-31 | Affymax Technologies N.V. | Peptide library and screening method |
| ES2341666T3 (es) * | 1991-12-02 | 2010-06-24 | Medimmune Limited | Produccion de autoanticuerpos de repertorios de segmentos de anticue rpos expresados en la superficie de fagos. |
| US6511845B1 (en) | 1992-08-07 | 2003-01-28 | Alan R. Davis | Methods for producing an immune response against HIV-1 |
| US6057093A (en) * | 1992-09-28 | 2000-05-02 | Chiron Corporation | Methods and compositions for controlling translation of HCV proteins |
| US5633234A (en) * | 1993-01-22 | 1997-05-27 | The Johns Hopkins University | Lysosomal targeting of immunogens |
| US6296852B1 (en) | 1993-04-14 | 2001-10-02 | Commonwealth Scientific And Industrial Research Organisation | Recombinant avian adenovirus vector |
| DE69435081T2 (de) * | 1993-04-14 | 2008-06-12 | Commonwealth Scientific And Industrial Research Organisation | Rekombinanter adenovirusvektor für geflügel |
| AU676042B2 (en) * | 1993-04-14 | 1997-02-27 | Commonwealth Scientific And Industrial Research Organisation | Recombinant avian adenovirus vector |
| US6010861A (en) * | 1994-08-03 | 2000-01-04 | Dgi Biotechnologies, Llc | Target specific screens and their use for discovering small organic molecular pharmacophores |
| US5846782A (en) | 1995-11-28 | 1998-12-08 | Genvec, Inc. | Targeting adenovirus with use of constrained peptide motifs |
| US5965541A (en) * | 1995-11-28 | 1999-10-12 | Genvec, Inc. | Vectors and methods for gene transfer to cells |
| US5962311A (en) * | 1994-09-08 | 1999-10-05 | Genvec, Inc. | Short-shafted adenoviral fiber and its use |
| US6465253B1 (en) * | 1994-09-08 | 2002-10-15 | Genvec, Inc. | Vectors and methods for gene transfer to cells |
| US5559099A (en) * | 1994-09-08 | 1996-09-24 | Genvec, Inc. | Penton base protein and methods of using same |
| CA2202761A1 (en) | 1994-10-18 | 1996-04-25 | Sean Nicholas Chapman | Method of producing a chimeric protein |
| US5770442A (en) * | 1995-02-21 | 1998-06-23 | Cornell Research Foundation, Inc. | Chimeric adenoviral fiber protein and methods of using same |
| US6127525A (en) * | 1995-02-21 | 2000-10-03 | Cornell Research Foundation, Inc. | Chimeric adenoviral coat protein and methods of using same |
| US5994128A (en) | 1995-06-15 | 1999-11-30 | Introgene B.V. | Packaging systems for human recombinant adenovirus to be used in gene therapy |
| US6783980B2 (en) * | 1995-06-15 | 2004-08-31 | Crucell Holland B.V. | Packaging systems for human recombinant adenovirus to be used in gene therapy |
| US6083693A (en) | 1996-06-14 | 2000-07-04 | Curagen Corporation | Identification and comparison of protein-protein interactions that occur in populations |
| AU4070499A (en) | 1998-04-30 | 1999-11-16 | Cornell Research Foundation Inc. | Adenoviral vectors with tandem fiber proteins |
| US20040043489A1 (en) * | 1998-07-08 | 2004-03-04 | Menzo Havenga | Gene delivery vectors provided with a tissue tropism for dendritic cells and methods of use |
| US20030017138A1 (en) * | 1998-07-08 | 2003-01-23 | Menzo Havenga | Chimeric adenoviruses |
| AU767975B2 (en) | 1998-09-11 | 2003-11-27 | Genvec, Inc. | Alternatively targeted adenovirus |
| US6929946B1 (en) * | 1998-11-20 | 2005-08-16 | Crucell Holland B.V. | Gene delivery vectors provided with a tissue tropism for smooth muscle cells, and/or endothelial cells |
| US20050232900A1 (en) * | 1999-05-18 | 2005-10-20 | Crucell Holland B.V. | Serotype of adenovirus and uses thereof |
| US6913922B1 (en) * | 1999-05-18 | 2005-07-05 | Crucell Holland B.V. | Serotype of adenovirus and uses thereof |
| US6492169B1 (en) | 1999-05-18 | 2002-12-10 | Crucell Holland, B.V. | Complementing cell lines |
| EP1157999A1 (en) * | 2000-05-24 | 2001-11-28 | Introgene B.V. | Methods and means for enhancing skin transplantation using gene delivery vehicles having tropism for primary fibroblasts, as well as other uses thereof |
| WO2001092549A2 (en) * | 2000-05-31 | 2001-12-06 | Genvec, Inc. | Method and composition for targeting an adenoviral vector |
| EP1322774A2 (en) * | 2000-09-20 | 2003-07-02 | Crucell Holland B.V. | Gene delivery vectors provided with a tissue tropism for dendritic cells |
| DE60138403D1 (de) * | 2000-09-26 | 2009-05-28 | Crucell Holland Bv | Adenovirale vektoren für die übertragung von genen in zellen der skelettmuskulatur oder myoblasten |
| EP1345967B1 (en) * | 2000-12-22 | 2011-08-10 | Grad, Carole, Legal representative of Kaplan, Howard | Phage display libraries of human v h fragments |
| US20030148380A1 (en) * | 2001-06-05 | 2003-08-07 | Belcher Angela M. | Molecular recognition of materials |
| US20050164515A9 (en) * | 2001-06-05 | 2005-07-28 | Belcher Angela M. | Biological control of nanoparticle nucleation, shape and crystal phase |
| US20030113714A1 (en) * | 2001-09-28 | 2003-06-19 | Belcher Angela M. | Biological control of nanoparticles |
| US20030073104A1 (en) * | 2001-10-02 | 2003-04-17 | Belcher Angela M. | Nanoscaling ordering of hybrid materials using genetically engineered mesoscale virus |
| BR0308783A (pt) * | 2002-04-25 | 2005-01-04 | Crucell Holland Bv | Vetor de adenovìrus recombinante, método para produzir um vetor de adenovìrus recombinante, composição farmacêutica, método para tratar um corpo humano, e, kit de partes |
| US20050064508A1 (en) * | 2003-09-22 | 2005-03-24 | Semzyme | Peptide mediated synthesis of metallic and magnetic materials |
| WO2004089310A2 (en) * | 2003-03-31 | 2004-10-21 | The Board Of Regents Of The University Of Texas System | High-throughput assay for virus entry and drug screening |
| AU2008279584A1 (en) * | 2007-04-27 | 2009-01-29 | Dow Global Technologies Inc. | Improved production and in vivo assembly of soluble recombinant icosahedral virus-like particles |
| US10736928B2 (en) | 2016-01-20 | 2020-08-11 | Richard Brian Murphy, JR. | Pegylated recombinant bacteriophage |
| CA3044074A1 (en) | 2016-11-16 | 2018-05-24 | Immunomic Therapeutics, Inc. | Nucleic acids for treatment of allergies |
| CN110799529A (zh) | 2017-04-22 | 2020-02-14 | 免疫治疗有限公司 | 改良lamp构建物 |
| CN110913892A (zh) | 2017-05-02 | 2020-03-24 | 免疫治疗有限公司 | 包含癌抗原的lamp(溶酶体相关膜蛋白)构建物 |
| CA3100004A1 (en) | 2018-05-15 | 2019-11-21 | Immunomic Therapeutics, Inc. | Improved lamp constructs comprising allergens |
| CN112533629A (zh) | 2018-06-19 | 2021-03-19 | 阿尔莫生物科技股份有限公司 | 结合使用il-10药剂与嵌合抗原受体细胞疗法的组合物和方法 |
| US20240108703A1 (en) | 2019-10-18 | 2024-04-04 | Immunomic Therapeutics, Inc. | Improved LAMP Constructs Comprising Cancer Antigens |
| CA3166420A1 (en) | 2020-01-14 | 2021-07-22 | Synthekine, Inc. | Il2 orthologs and methods of use |
| WO2022147108A1 (en) | 2020-12-30 | 2022-07-07 | Immunomic Therapeutics, Inc. | Anti-hvem antibodies |
| WO2023201201A1 (en) | 2022-04-10 | 2023-10-19 | Immunomic Therapeutics, Inc. | Bicistronic lamp constructs comprising immune response enhancing genes and methods of use thereof |
| WO2025155971A1 (en) | 2024-01-19 | 2025-07-24 | Immunomic Therapeutics, Inc | Anti-activin receptor 1c (alk-7) receptor antibodies |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2712615A1 (de) * | 1977-03-18 | 1978-09-21 | Max Planck Gesellschaft | Verfahren zur herstellung von filamentoesen phagen als vektor fuer synthetische rekombinate |
| JPS53133684A (en) * | 1977-04-26 | 1978-11-21 | Noda Sangyo Kagaku Kenkyusho | Novel bacteriophage and fabricating same |
| DE2860386D1 (en) * | 1978-01-05 | 1981-03-19 | Bayer Ag | Molding compositions consisting essentially of unsaturated polyesters, method of preparation and application |
| JPS5558096A (en) * | 1978-10-25 | 1980-04-30 | Noda Sangyo Kagaku Kenkyusho | Method of making novel recombined dna |
| JPS5561798A (en) * | 1978-10-30 | 1980-05-09 | Noda Sangyo Kagaku Kenkyusho | Preparation of novel recombination dna |
| FR2442271A1 (fr) * | 1978-11-27 | 1980-06-20 | Pasteur Institut | Vecteur permettant l'insertion d'un gene procaryote ou eucaryote, et l'excretion de la proteine exprimee |
| FR2480779B2 (fr) * | 1979-08-30 | 1986-07-18 | Anvar | Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur |
| US4442205A (en) * | 1981-09-22 | 1984-04-10 | The United States Of America As Represented By The Department Of Health And Human Services | Simian virus recombinant that directs the synthesis of hepatitis B surface antigen |
-
1982
- 1982-01-11 US US06/338,416 patent/US4593002A/en not_active Expired - Lifetime
-
1983
- 1983-01-05 ZA ZA8358A patent/ZA8358B/xx unknown
- 1983-01-06 NZ NZ202954A patent/NZ202954A/en unknown
- 1983-01-07 WO PCT/US1983/000015 patent/WO1983002393A1/en not_active Ceased
- 1983-01-07 AU AU11596/83A patent/AU562548B2/en not_active Ceased
- 1983-01-07 EP EP83900590A patent/EP0098299B1/en not_active Expired
- 1983-01-07 FI FI833174A patent/FI833174A7/fi not_active Application Discontinuation
- 1983-01-07 CA CA000419086A patent/CA1211060A/en not_active Expired
- 1983-01-07 GR GR70220A patent/GR77173B/el unknown
- 1983-01-07 GB GB08322556A patent/GB2125065B/en not_active Expired
- 1983-01-07 DE DE8383900590T patent/DE3367851D1/de not_active Expired
- 1983-01-07 JP JP58500629A patent/JP2593295B2/ja not_active Expired - Lifetime
- 1983-01-10 PT PT76079A patent/PT76079B/pt unknown
- 1983-01-10 ES ES518870A patent/ES518870A0/es active Granted
- 1983-07-10 IT IT47530/83A patent/IT1164858B/it active
- 1983-09-08 NO NO833205A patent/NO833205L/no unknown
Non-Patent Citations (1)
| Title |
|---|
| Proc・Natl.Acad.Sci.USA,Vol.78 No.9(1981)P.5488−5492 |
Also Published As
| Publication number | Publication date |
|---|---|
| ES8500322A1 (es) | 1984-10-01 |
| DE3367851D1 (en) | 1987-01-15 |
| NZ202954A (en) | 1985-08-16 |
| FI833174A0 (fi) | 1983-09-06 |
| FI833174L (fi) | 1983-09-06 |
| CA1211060A (en) | 1986-09-09 |
| GB8322556D0 (en) | 1983-09-21 |
| FI833174A7 (fi) | 1983-09-06 |
| GB2125065A (en) | 1984-02-29 |
| AU1159683A (en) | 1983-07-28 |
| EP0098299B1 (en) | 1986-11-26 |
| GB2125065B (en) | 1985-05-15 |
| IT8347530A0 (it) | 1983-07-10 |
| WO1983002393A1 (en) | 1983-07-21 |
| US4593002A (en) | 1986-06-03 |
| EP0098299A1 (en) | 1984-01-18 |
| PT76079A (en) | 1983-02-01 |
| JPS59500042A (ja) | 1984-01-12 |
| EP0098299A4 (en) | 1984-07-05 |
| IT1164858B (it) | 1987-04-15 |
| NO833205L (no) | 1983-09-08 |
| AU562548B2 (en) | 1987-06-11 |
| PT76079B (en) | 1985-11-11 |
| GR77173B (enExample) | 1984-09-10 |
| ZA8358B (en) | 1983-10-26 |
| ES518870A0 (es) | 1984-10-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2593295B2 (ja) | 組換え体表面タンパク質を持つウイルス | |
| KR0179994B1 (ko) | 칠면조의 재조합 포진바이러스 및 이로부터 유도된 생존상태의 벡터 백신 | |
| Casais et al. | Reverse genetics system for the avian coronavirus infectious bronchitis virus | |
| JP3159446B2 (ja) | 組換えアデノウイルス | |
| CN111603557A (zh) | 一种包膜替换型病毒载体疫苗及其构建方法 | |
| JPH06506583A (ja) | ベクターとして修正された植物ウイルス | |
| Kakach et al. | Rift Valley fever virus M segment: use of recombinant vaccinia viruses to study Phlebovirus gene expression | |
| JPH06505392A (ja) | 弱毒化され、遺伝子的に加工されたシュードラビーウイルスs−prv−155およびその使用 | |
| HU230488B1 (hu) | Simian adenovírus nukleinsav és aminosav-szekvencia, azt tartalmazó vektorok, és eljárások annak alkalmazására | |
| JPH0671429B2 (ja) | 変異化ワクチニアウイルス並びにその製造及び使用方法 | |
| US7645455B2 (en) | Chimeric lyssavirus nucleic acids and polypeptides | |
| EP0117767A1 (en) | Production of parvovirus subunit vaccines | |
| CN110951699B (zh) | 表达犬瘟热病毒结构蛋白的重组狂犬病病毒及其应用 | |
| CA1295561C (en) | Production of herpes simplex viral proteins | |
| JPH05508538A (ja) | 馬ヘルペスウィルス―4 tk ̄ワクチン | |
| WO1984002847A1 (en) | Methods and materials for development of parvovirus vaccine | |
| JP2786625B2 (ja) | 単純ヘルペスウイルスタンパク質をコードするdna配列 | |
| JPH05501950A (ja) | 変異株仮性狂犬病ウィルス及びそれを含有するワクチン | |
| RU2215035C2 (ru) | Рекомбинантный полиовирусный вектор (варианты), способ его получения (варианты), способ индукции иммунного ответа у индивидуума (варианты), способ получения белка (варианты), вакцинная композиция для терапии или профилактики инфекционных заболеваний (варианты) | |
| CN111454989A (zh) | 一种嵌合型基因i型乙型脑炎病毒病毒样颗粒疫苗及其制备方法和应用 | |
| CN113337476A (zh) | 一种口蹄疫O型PanAsia-2谱系储备疫苗毒株及其构建方法和应用 | |
| US5182211A (en) | Plasmid vectors encoding a protein of a picornavirus | |
| AU674134B2 (en) | Recombinant viruses comprising artificial proteolytic cleavage site | |
| Seal et al. | Isolation of caliciviruses from skunks that are antigenically and genotypically related to San Miguel sea lion virus | |
| WO1994029472A2 (en) | Mengovirus as a vector for expression of foreign polypeptides |