|
US4217344A
(en)
|
1976-06-23 |
1980-08-12 |
L'oreal |
Compositions containing aqueous dispersions of lipid spheres
|
|
US4196265A
(en)
|
1977-06-15 |
1980-04-01 |
The Wistar Institute |
Method of producing antibodies
|
|
US4235871A
(en)
|
1978-02-24 |
1980-11-25 |
Papahadjopoulos Demetrios P |
Method of encapsulating biologically active materials in lipid vesicles
|
|
US4186183A
(en)
|
1978-03-29 |
1980-01-29 |
The United States Of America As Represented By The Secretary Of The Army |
Liposome carriers in chemotherapy of leishmaniasis
|
|
US4261975A
(en)
|
1979-09-19 |
1981-04-14 |
Merck & Co., Inc. |
Viral liposome particle
|
|
US4485054A
(en)
|
1982-10-04 |
1984-11-27 |
Lipoderm Pharmaceuticals Limited |
Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV)
|
|
US4501728A
(en)
|
1983-01-06 |
1985-02-26 |
Technology Unlimited, Inc. |
Masking of liposomes from RES recognition
|
|
US5380831A
(en)
|
1986-04-04 |
1995-01-10 |
Mycogen Plant Science, Inc. |
Synthetic insecticidal crystal protein gene
|
|
US4897355A
(en)
|
1985-01-07 |
1990-01-30 |
Syntex (U.S.A.) Inc. |
N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
|
|
US4946787A
(en)
|
1985-01-07 |
1990-08-07 |
Syntex (U.S.A.) Inc. |
N-(ω,(ω-1)-dialkyloxy)- and N-(ω,(ω-1)-dialkenyloxy)-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
|
|
US5049386A
(en)
|
1985-01-07 |
1991-09-17 |
Syntex (U.S.A.) Inc. |
N-ω,(ω-1)-dialkyloxy)- and N-(ω,(ω-1)-dialkenyloxy)Alk-1-YL-N,N,N-tetrasubstituted ammonium lipids and uses therefor
|
|
US4797368A
(en)
|
1985-03-15 |
1989-01-10 |
The United States Of America As Represented By The Department Of Health And Human Services |
Adeno-associated virus as eukaryotic expression vector
|
|
US5569597A
(en)
|
1985-05-13 |
1996-10-29 |
Ciba Geigy Corp. |
Methods of inserting viral DNA into plant material
|
|
US4774085A
(en)
|
1985-07-09 |
1988-09-27 |
501 Board of Regents, Univ. of Texas |
Pharmaceutical administration systems containing a mixture of immunomodulators
|
|
US4853331A
(en)
|
1985-08-16 |
1989-08-01 |
Mycogen Corporation |
Cloning and expression of Bacillus thuringiensis toxin gene toxic to beetles of the order Coleoptera
|
|
US5268463A
(en)
|
1986-11-11 |
1993-12-07 |
Jefferson Richard A |
Plant promoter α-glucuronidase gene construct
|
|
US5608142A
(en)
|
1986-12-03 |
1997-03-04 |
Agracetus, Inc. |
Insecticidal cotton plants
|
|
US4837028A
(en)
|
1986-12-24 |
1989-06-06 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
|
US5039523A
(en)
|
1988-10-27 |
1991-08-13 |
Mycogen Corporation |
Novel Bacillus thuringiensis isolate denoted B.t. PS81F, active against lepidopteran pests, and a gene encoding a lepidopteran-active toxin
|
|
EP0463056A1
(en)
|
1989-03-17 |
1992-01-02 |
E.I. Du Pont De Nemours And Company |
External regulation of gene expression
|
|
EP0452269B1
(en)
|
1990-04-12 |
2002-10-09 |
Syngenta Participations AG |
Tissue-preferential promoters
|
|
US5264618A
(en)
|
1990-04-19 |
1993-11-23 |
Vical, Inc. |
Cationic lipids for intracellular delivery of biologically active molecules
|
|
WO1991017424A1
(en)
|
1990-05-03 |
1991-11-14 |
Vical, Inc. |
Intracellular delivery of biologically active substances by means of self-assembling lipid complexes
|
|
US5498830A
(en)
|
1990-06-18 |
1996-03-12 |
Monsanto Company |
Decreased oil content in plant seeds
|
|
CA2051562C
(en)
|
1990-10-12 |
2003-12-02 |
Jewel M. Payne |
Bacillus thuringiensis isolates active against dipteran pests
|
|
US5173414A
(en)
|
1990-10-30 |
1992-12-22 |
Applied Immune Sciences, Inc. |
Production of recombinant adeno-associated virus vectors
|
|
US5399680A
(en)
|
1991-05-22 |
1995-03-21 |
The Salk Institute For Biological Studies |
Rice chitinase promoter
|
|
CA2116449C
(en)
|
1991-08-27 |
2005-04-05 |
Vaughan Alan Hilder |
Proteins with insecticidal properties against homopteran insects and their use in plant protection
|
|
TW261517B
(https=)
|
1991-11-29 |
1995-11-01 |
Mitsubishi Shozi Kk |
|
|
US5587308A
(en)
|
1992-06-02 |
1996-12-24 |
The United States Of America As Represented By The Department Of Health & Human Services |
Modified adeno-associated virus vector capable of expression from a novel promoter
|
|
US5789156A
(en)
|
1993-06-14 |
1998-08-04 |
Basf Ag |
Tetracycline-regulated transcriptional inhibitors
|
|
US5814618A
(en)
|
1993-06-14 |
1998-09-29 |
Basf Aktiengesellschaft |
Methods for regulating gene expression
|
|
US5605793A
(en)
|
1994-02-17 |
1997-02-25 |
Affymax Technologies N.V. |
Methods for in vitro recombination
|
|
US5837458A
(en)
|
1994-02-17 |
1998-11-17 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
|
US5608144A
(en)
|
1994-08-12 |
1997-03-04 |
Dna Plant Technology Corp. |
Plant group 2 promoters and uses thereof
|
|
US5659026A
(en)
|
1995-03-24 |
1997-08-19 |
Pioneer Hi-Bred International |
ALS3 promoter
|
|
US6072050A
(en)
|
1996-06-11 |
2000-06-06 |
Pioneer Hi-Bred International, Inc. |
Synthetic promoters
|
|
CA2315546C
(en)
|
1998-02-26 |
2008-04-29 |
Pioneer Hi-Bred International, Inc. |
Constitutive maize promoters
|
|
US6484690B2
(en)
|
1999-01-06 |
2002-11-26 |
Hitachi, Ltd. |
Control equipment for internal combustion engines
|
|
US6534261B1
(en)
|
1999-01-12 |
2003-03-18 |
Sangamo Biosciences, Inc. |
Regulation of endogenous gene expression in cells using zinc finger proteins
|
|
CZ20013894A3
(cs)
|
1999-05-04 |
2002-04-17 |
Monsanto Technology Llc |
Polypeptidové kompozice toxické pro hmyz z řádu Coleoptera a transgenní rostliny rezistentní proti hmyzu
|
|
AU7491600A
(en)
|
1999-09-15 |
2001-04-17 |
Monsanto Technology Llc |
Lepidopteran-active bacillus thuringiensis delta-endotoxin compositions and methods of use
|
|
DK2359869T3
(en)
|
2001-12-17 |
2019-04-15 |
Univ Pennsylvania |
Sequences of adeno-associated virus (AAV) serotype 8, vectors containing these, and uses thereof
|
|
US20050183161A1
(en)
|
2003-10-14 |
2005-08-18 |
Athenix Corporation |
AXMI-010, a delta-endotoxin gene and methods for its use
|
|
US7629504B2
(en)
|
2003-12-22 |
2009-12-08 |
Pioneer Hi-Bred International, Inc. |
Bacillus thuringiensis cry9 nucleic acids
|
|
NZ573398A
(en)
|
2006-06-14 |
2011-11-25 |
Athenix Corp |
Axmi-031, axmi-039, axmi-040 and axmi-049, a family of delta-endotoxin genes and methods for their use
|
|
EP2334794B8
(en)
|
2008-09-15 |
2017-04-19 |
The Children's Medical Center Corporation |
Modulation of bcl11a for treatment of hemoglobinopathies
|
|
US9392788B2
(en)
*
|
2008-11-07 |
2016-07-19 |
North Carolina State University |
Mosquito attractant compositions and methods
|
|
MX346215B
(es)
|
2009-07-02 |
2017-03-10 |
Athenix Corp |
Gen plaguicida axmi-205 y metodos para su uso.
|
|
WO2011084324A2
(en)
|
2009-12-21 |
2011-07-14 |
Pioneer Hi-Bred International, Inc. |
Novel bacillus thuringiensis gene with lepidopteran activity
|
|
WO2012024200A2
(en)
|
2010-08-19 |
2012-02-23 |
Pioneer Hi-Bred International, Inc. |
Novel bacillus thuringiensis gene with lepidopteran activity
|
|
US9405700B2
(en)
|
2010-11-04 |
2016-08-02 |
Sonics, Inc. |
Methods and apparatus for virtualization in an integrated circuit
|
|
EP3241902B1
(en)
|
2012-05-25 |
2018-02-28 |
The Regents of The University of California |
Methods and compositions for rna-directed target dna modification and for rna-directed modulation of transcription
|
|
DK3444342T3
(da)
|
2012-07-11 |
2020-08-24 |
Sangamo Therapeutics Inc |
Fremgangsmåder og sammensætninger til behandlingen af lysosomale aflejringssygdomme
|
|
US20150165054A1
(en)
|
2013-12-12 |
2015-06-18 |
President And Fellows Of Harvard College |
Methods for correcting caspase-9 point mutations
|
|
EP3633032A3
(en)
|
2014-08-28 |
2020-07-29 |
North Carolina State University |
Novel cas9 proteins and guiding features for dna targeting and genome editing
|
|
CN107849546A
(zh)
*
|
2015-05-15 |
2018-03-27 |
先锋国际良种公司 |
对cas内切核酸酶系统、pam序列和指导rna元件的快速表征
|
|
US9790490B2
(en)
|
2015-06-18 |
2017-10-17 |
The Broad Institute Inc. |
CRISPR enzymes and systems
|
|
JP7109784B2
(ja)
|
2015-10-23 |
2022-08-01 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
遺伝子編集のための進化したＣａｓ９蛋白質
|
|
AU2016380351B2
(en)
*
|
2015-12-29 |
2023-04-06 |
Monsanto Technology Llc |
Novel CRISPR-associated transposases and uses thereof
|
|
KR102547316B1
(ko)
|
2016-08-03 |
2023-06-23 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
아데노신 핵염기 편집제 및 그의 용도
|
|
AU2018240515B2
(en)
*
|
2017-03-24 |
2024-07-25 |
CureVac SE |
Nucleic acids encoding CRISPR-associated proteins and uses thereof
|
|
KR20200124702A
(ko)
*
|
2018-02-23 |
2020-11-03 |
파이어니어 하이 부렛드 인터내쇼날 인코포레이팃드 |
신규한 cas9 오르소로그
|
|
US20220096543A1
(en)
|
2018-12-24 |
2022-03-31 |
Virgina Tech Intellectual Properties, Inc. |
Tollip deficient neutrophils and uses thereof
|
|
ES2970169T3
(es)
*
|
2018-12-27 |
2024-05-27 |
Lifeedit Therapeutics Inc |
Polipéptidos útiles para edición génica y métodos de uso
|
|
US11946077B2
(en)
*
|
2020-06-04 |
2024-04-02 |
Emendobio Inc. |
OMNI-59, 61, 67, 76, 79, 80, 81, and 82 CRISPR nucleases
|
|
EP4274894A2
(en)
|
2021-01-11 |
2023-11-15 |
The Broad Institute, Inc. |
Prime editor variants, constructs, and methods for enhancing prime editing efficiency and precision
|