JP2023546158A5 - - Google Patents

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Publication number
JP2023546158A5
JP2023546158A5 JP2023523535A JP2023523535A JP2023546158A5 JP 2023546158 A5 JP2023546158 A5 JP 2023546158A5 JP 2023523535 A JP2023523535 A JP 2023523535A JP 2023523535 A JP2023523535 A JP 2023523535A JP 2023546158 A5 JP2023546158 A5 JP 2023546158A5
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JP
Japan
Prior art keywords
sequence
nucleic acid
guide molecule
car
molecule according
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JP2023523535A
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English (en)
Japanese (ja)
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JP2023546158A (ja
JP7698715B2 (ja
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Priority claimed from PCT/US2021/055394 external-priority patent/WO2022086846A2/en
Publication of JP2023546158A publication Critical patent/JP2023546158A/ja
Publication of JP2023546158A5 publication Critical patent/JP2023546158A5/ja
Application granted granted Critical
Publication of JP7698715B2 publication Critical patent/JP7698715B2/ja
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JP2023523535A 2020-10-19 2021-10-18 Crispr v型系のためのdna含有ポリヌクレオチドおよびガイド、ならびにこれらを製造する方法および使用する方法 Active JP7698715B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US202063093459P 2020-10-19 2020-10-19
US63/093,459 2020-10-19
US202063127648P 2020-12-18 2020-12-18
US63/127,648 2020-12-18
US202163229870P 2021-08-05 2021-08-05
US63/229,870 2021-08-05
PCT/US2021/055394 WO2022086846A2 (en) 2020-10-19 2021-10-18 Dna-containing polynucleotides and guides for crispr type v systems, and methods of making and using the same

Publications (3)

Publication Number Publication Date
JP2023546158A JP2023546158A (ja) 2023-11-01
JP2023546158A5 true JP2023546158A5 (https=) 2023-11-09
JP7698715B2 JP7698715B2 (ja) 2025-06-25

Family

ID=78819995

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023523535A Active JP7698715B2 (ja) 2020-10-19 2021-10-18 Crispr v型系のためのdna含有ポリヌクレオチドおよびガイド、ならびにこれらを製造する方法および使用する方法

Country Status (9)

Country Link
US (1) US20250027078A1 (https=)
EP (1) EP4229198A2 (https=)
JP (1) JP7698715B2 (https=)
KR (1) KR20230090337A (https=)
AU (1) AU2021364314C1 (https=)
CA (1) CA3198905A1 (https=)
IL (1) IL302220A (https=)
MX (1) MX2023004505A (https=)
WO (1) WO2022086846A2 (https=)

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CN110494559B (zh) * 2017-03-28 2023-10-31 味之素株式会社 不分化地维持用培养基添加剂
EP4508211A2 (en) * 2022-04-13 2025-02-19 Caribou Biosciences, Inc. Therapeutic applications of crispr type v systems
WO2023225035A2 (en) * 2022-05-16 2023-11-23 Artisan Development Labs, Inc. Compositions and methods for engineering cells
EP4504764A1 (en) 2022-05-26 2025-02-12 Caribou Biosciences, Inc. Cytokine-receptor fusions for immune cell stimulation
WO2024046307A1 (zh) * 2022-08-29 2024-03-07 北京迅识科技有限公司 一种突变的v型crispr酶及其应用
AU2023353989A1 (en) 2022-09-30 2025-02-27 Caribou Biosciences, Inc. Anti-ror1 chimeric antigen receptors (cars), cells expressing the cars and related methods
WO2024102434A1 (en) 2022-11-10 2024-05-16 Senda Biosciences, Inc. Rna compositions comprising lipid nanoparticles or lipid reconstructed natural messenger packs
EP4584283A1 (en) 2022-11-14 2025-07-16 Caribou Biosciences, Inc. Anti-cll-1 chimeric antigen receptors, engineered cells and related methods
AU2024236558A1 (en) 2023-03-15 2025-10-09 Renagade Therapeutics Management Inc. Delivery of gene editing systems and methods of use thereof
EP4704886A1 (en) * 2023-05-01 2026-03-11 Caribou Biosciences, Inc. Treatment of autoimmune diseases with bcma-targeting engineered immune cells
WO2025006880A1 (en) 2023-06-29 2025-01-02 Caribou Biosciences, Inc. Diagnostic and therapeutic methods for use with ror1 antagonists
WO2025024679A1 (en) * 2023-07-26 2025-01-30 Caribou Biosciences, Inc. In vitro validation methods for car-t cell therapies
AU2024335327A1 (en) 2023-09-01 2026-03-26 Renagade Therapeutics Management Inc. Gene editing systems, compositions, and methods for treatment of vexas syndrome
WO2025117745A1 (en) 2023-12-01 2025-06-05 Caribou Biosciences, Inc. Methods and compositions for improving precision of endonuclease-mediated genome editing
WO2025174765A1 (en) 2024-02-12 2025-08-21 Renagade Therapeutics Management Inc. Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents
WO2025231432A1 (en) * 2024-05-03 2025-11-06 Caribou Biosciences, Inc. In vivo gene editing with crispr systems
WO2026024468A1 (en) 2024-07-26 2026-01-29 Caribou Biosciences, Inc. Modular linked chimeric antigen receptors
CN119881333B (zh) * 2025-01-27 2025-11-28 上海市肿瘤研究所 一种dna纳米花级联crispr系统的蛋白标志物检测平台及其构建方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9650617B2 (en) * 2015-01-28 2017-05-16 Pioneer Hi-Bred International. Inc. CRISPR hybrid DNA/RNA polynucleotides and methods of use
EP3423580A1 (en) * 2016-03-04 2019-01-09 Editas Medicine, Inc. Crispr-cpf1-related methods, compositions and components for cancer immunotherapy
CN105912952B (zh) * 2016-05-04 2019-07-23 广州广电运通金融电子股份有限公司 一种基于Linux的注册表服务系统、方法及金融自助设备
WO2017190664A1 (zh) * 2016-05-05 2017-11-09 苏州吉玛基因股份有限公司 化学合成的crRNA和修饰crRNA在CRISPR/Cpf1基因编辑系统中的应用
MX2018014993A (es) * 2016-06-14 2019-09-06 Pioneer Hi Bred Int Uso de endonucleasa cpf1 para modificaciones de genoma de planta.
WO2018009822A1 (en) * 2016-07-08 2018-01-11 Ohio State Innovation Foundation Modified nucleic acids, hybrid guide rnas, and uses thereof
EP3562942A4 (en) * 2016-12-28 2020-12-09 Ionis Pharmaceuticals, Inc. MODIFIED CRISPR-RNA AND ITS USES
CN110616189B (zh) * 2018-06-20 2022-02-18 西安桑尼赛尔生物医药有限公司 通用型靶向cd19抗原嵌合受体t细胞的制备及其应用
WO2020007593A1 (en) * 2018-07-02 2020-01-09 Cellectis Chimeric antigen receptors (car)-expressing cells and combination treatment for immunotherapy of patients with relapse refractory adverse genetic risk aml
PE20211959A1 (es) * 2019-02-15 2021-09-30 Editas Medicine Inc Celulas asesinas naturales (nk) modificadas para inmunoterapia

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