JP2022516130A5 - - Google Patents
Info
- Publication number
- JP2022516130A5 JP2022516130A5 JP2021538143A JP2021538143A JP2022516130A5 JP 2022516130 A5 JP2022516130 A5 JP 2022516130A5 JP 2021538143 A JP2021538143 A JP 2021538143A JP 2021538143 A JP2021538143 A JP 2021538143A JP 2022516130 A5 JP2022516130 A5 JP 2022516130A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sequence
- position corresponding
- amino acid
- polypeptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024008844A JP2024050676A (ja) | 2018-12-27 | 2024-01-24 | 遺伝子編集に有用なポリペプチドと利用方法 |
| JP2024112452A JP2024137967A (ja) | 2018-12-27 | 2024-07-12 | 遺伝子編集に有用なポリペプチドと利用方法 |
Applications Claiming Priority (15)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862785391P | 2018-12-27 | 2018-12-27 | |
| US62/785,391 | 2018-12-27 | ||
| US201962790261P | 2019-01-09 | 2019-01-09 | |
| US201962790256P | 2019-01-09 | 2019-01-09 | |
| US201962790266P | 2019-01-09 | 2019-01-09 | |
| US201962790258P | 2019-01-09 | 2019-01-09 | |
| US201962790262P | 2019-01-09 | 2019-01-09 | |
| US62/790,258 | 2019-01-09 | ||
| US62/790,256 | 2019-01-09 | ||
| US62/790,261 | 2019-01-09 | ||
| US62/790,262 | 2019-01-09 | ||
| US62/790,266 | 2019-01-09 | ||
| US201962932169P | 2019-11-07 | 2019-11-07 | |
| US62/932,169 | 2019-11-07 | ||
| PCT/US2019/068079 WO2020139783A2 (en) | 2018-12-27 | 2019-12-20 | Polypeptides useful for gene editing and methods of use |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024008844A Division JP2024050676A (ja) | 2018-12-27 | 2024-01-24 | 遺伝子編集に有用なポリペプチドと利用方法 |
| JP2024112452A Division JP2024137967A (ja) | 2018-12-27 | 2024-07-12 | 遺伝子編集に有用なポリペプチドと利用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022516130A JP2022516130A (ja) | 2022-02-24 |
| JP2022516130A5 true JP2022516130A5 (https=) | 2022-12-27 |
| JP7572360B2 JP7572360B2 (ja) | 2024-10-23 |
Family
ID=69182752
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021538143A Active JP7572360B2 (ja) | 2018-12-27 | 2019-12-20 | 遺伝子編集に有用なポリペプチドと利用方法 |
| JP2024008844A Pending JP2024050676A (ja) | 2018-12-27 | 2024-01-24 | 遺伝子編集に有用なポリペプチドと利用方法 |
| JP2024112452A Pending JP2024137967A (ja) | 2018-12-27 | 2024-07-12 | 遺伝子編集に有用なポリペプチドと利用方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024008844A Pending JP2024050676A (ja) | 2018-12-27 | 2024-01-24 | 遺伝子編集に有用なポリペプチドと利用方法 |
| JP2024112452A Pending JP2024137967A (ja) | 2018-12-27 | 2024-07-12 | 遺伝子編集に有用なポリペプチドと利用方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US20220145296A1 (https=) |
| EP (2) | EP4339286A3 (https=) |
| JP (3) | JP7572360B2 (https=) |
| KR (1) | KR20210149686A (https=) |
| CN (1) | CN113631704A (https=) |
| AU (2) | AU2019416108B2 (https=) |
| BR (1) | BR112021012665A2 (https=) |
| ES (1) | ES2970169T3 (https=) |
| IL (2) | IL312708A (https=) |
| MX (1) | MX2021007835A (https=) |
| NZ (1) | NZ778392A (https=) |
| SG (1) | SG11202106977PA (https=) |
| TW (1) | TW202039847A (https=) |
| WO (1) | WO2020139783A2 (https=) |
| ZA (1) | ZA202105281B (https=) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL3802807T3 (pl) * | 2018-06-05 | 2025-03-31 | Life Edit Therapeutics, Inc. | Nukleazy kierowane rna i ich aktywne fragmenty oraz warianty i sposoby ich zastosowania |
| TW202208626A (zh) | 2020-04-24 | 2022-03-01 | 美商生命編輯公司 | Rna引導核酸酶及其活性片段與變體，以及使用方法 |
| AU2021300378A1 (en) | 2020-07-01 | 2023-01-19 | Elevatebio Technologies, Inc. | Compositions and methods for cellular reprogramming using circular RNA |
| US20240247242A1 (en) * | 2020-07-15 | 2024-07-25 | LifeEDIT Therapeutics, Inc. | Uracil stabilizing proteins and active fragments and variants thereof and methods of use |
| MX2023002848A (es) * | 2020-09-11 | 2023-03-22 | Lifeedit Therapeutics Inc | Enzimas modificadoras del acido desoxirribonucleico (adn) y fragmentos activos y sus variantes y metodos de uso. |
| US20240301385A1 (en) * | 2021-03-22 | 2024-09-12 | LifeEDIT Therapeutics, Inc. | Dna modifying enzymes and active fragments and variants thereof and methods of use |
| AU2022272250A1 (en) * | 2021-05-14 | 2023-11-30 | Beam Therapeutics Inc. | Compositions and methods for treating transthyretin amyloidosis |
| EP4101928A1 (en) * | 2021-06-11 | 2022-12-14 | Bayer AG | Type v rna programmable endonuclease systems |
| AU2022290382A1 (en) * | 2021-06-11 | 2023-11-23 | Bayer Aktiengesellschaft | Type v rna programmable endonuclease systems |
| EP4352215A1 (en) | 2021-06-11 | 2024-04-17 | LifeEDIT Therapeutics, Inc. | Rna polymerase iii promoters and methods of use |
| AU2022336615A1 (en) | 2021-09-02 | 2024-04-11 | Sanofi Pasteur Inc. | Compositions and methods for rna affinity purification |
| WO2023057444A1 (en) | 2021-10-05 | 2023-04-13 | Sanofi | METHODS FOR FREEZING AND FREEZE-DRYING LIPID NANOPARTICLES (LNPs) AND LNPs OBTAINED WITH THE SAME |
| EP4453191A1 (en) * | 2021-12-23 | 2024-10-30 | Bayer Aktiengesellschaft | Novel small type v rna programmable endonuclease systems |
| CA3248846A1 (en) | 2022-01-17 | 2023-07-20 | Sanofi | Lipid Compounds and Their Uses |
| WO2023141602A2 (en) | 2022-01-21 | 2023-07-27 | Renagade Therapeutics Management Inc. | Engineered retrons and methods of use |
| CA3243220A1 (en) * | 2022-01-24 | 2023-07-27 | LifeEDIT Therapeutics, Inc. | RNA-GUIDED NUCLEASE AND ACTIVE FRAGMENTS, ASSOCIATED VARIANTS AND METHODS OF USE |
| JP2025520538A (ja) | 2022-06-17 | 2025-07-03 | サノフィ パスツール インコーポレイテッド | 環状ｒｎａ親和性精製のための組成物及び方法 |
| JP2025525569A (ja) | 2022-07-18 | 2025-08-05 | レナゲード セラピューティクス マネージメント インコーポレイテッド | 遺伝子編集成分、システム、及び使用方法 |
| EP4569093A1 (en) | 2022-08-12 | 2025-06-18 | Life Edit Therapeutics, Inc. | Rna-guided nucleases and active fragments and variants thereof and methods of use |
| CA3265664A1 (en) | 2022-08-25 | 2024-02-29 | Life Edit Therapeutics, Inc. | CHEMICAL MODIFICATION OF GUIDE RNA WITH A LOCKED NUCLEIC ACID FOR RNA-GUIDED NUCLEASE-MEDIATED GENE EDITING |
| WO2024044723A1 (en) | 2022-08-25 | 2024-02-29 | Renagade Therapeutics Management Inc. | Engineered retrons and methods of use |
| KR20250126155A (ko) | 2022-11-04 | 2025-08-22 | 라이프 에디트 테라퓨틱스, 인크. | 내부 삽입 부위를 갖는 진화된 아데닌 데아미나제 및 rna-가이드 뉴클레아제 융합 단백질 및 사용 방법 |
| WO2024127370A1 (en) | 2022-12-16 | 2024-06-20 | LifeEDIT Therapeutics, Inc. | Guide rnas that target trac gene and methods of use |
| EP4634383A1 (en) | 2022-12-16 | 2025-10-22 | Life Edit Therapeutics, Inc. | Guide rnas that target foxp3 gene and methods of use |
| WO2024178397A2 (en) | 2023-02-24 | 2024-08-29 | Elevatebio Technologies, Inc. | Modified immune effector cells and methods of use |
| WO2024235991A1 (en) * | 2023-05-15 | 2024-11-21 | UCB Biopharma SRL | Rna-guided nucleases and nucleic acid targeting systems comprising such rna-guided nucleases |
| WO2025003344A1 (en) * | 2023-06-28 | 2025-01-02 | Alia Therapeutics Srl | Type ii cas proteins and applications thereof |
| WO2025022367A2 (en) | 2023-07-27 | 2025-01-30 | Life Edit Therapeutics, Inc. | Rna-guided nucleases and active fragments and variants thereof and methods of use |
| AU2024357861A1 (en) | 2023-10-12 | 2026-04-23 | Renagade Therapeutics Management Inc. | Nickase-retron template-based precision editing system and methods of use |
| WO2025083619A1 (en) | 2023-10-18 | 2025-04-24 | Life Edit Therapeutics, Inc. | Rna-guided nucleases and acive fragments and variants thereof and methods of use |
| WO2025155753A2 (en) | 2024-01-17 | 2025-07-24 | Renagade Therapeutics Management Inc. | Improved gene editing system, guides, and methods |
| WO2025174908A1 (en) | 2024-02-12 | 2025-08-21 | Life Edit Therapeutics, Inc. | Novel rna-guided nucleases and proteins for polymerase editing |
| CN120608040A (zh) * | 2024-03-07 | 2025-09-09 | 清华大学 | 一种用于基因编辑和/或抵抗噬菌体的系统及其应用 |
| WO2025231360A1 (en) * | 2024-05-03 | 2025-11-06 | Modernatx, Inc. | Novel cas nucleases and polynucleotides encoding the same |
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-
2019
- 2019-12-20 KR KR1020217023648A patent/KR20210149686A/ko active Pending
- 2019-12-20 BR BR112021012665A patent/BR112021012665A2/pt unknown
- 2019-12-20 AU AU2019416108A patent/AU2019416108B2/en active Active
- 2019-12-20 JP JP2021538143A patent/JP7572360B2/ja active Active
- 2019-12-20 CN CN201980091657.4A patent/CN113631704A/zh active Pending
- 2019-12-20 US US17/418,498 patent/US20220145296A1/en active Pending
- 2019-12-20 SG SG11202106977PA patent/SG11202106977PA/en unknown
- 2019-12-20 ES ES19839624T patent/ES2970169T3/es active Active
- 2019-12-20 NZ NZ778392A patent/NZ778392A/en unknown
- 2019-12-20 MX MX2021007835A patent/MX2021007835A/es unknown
- 2019-12-20 IL IL312708A patent/IL312708A/en unknown
- 2019-12-20 EP EP23199688.5A patent/EP4339286A3/en active Pending
- 2019-12-20 WO PCT/US2019/068079 patent/WO2020139783A2/en not_active Ceased
- 2019-12-20 EP EP19839624.4A patent/EP3902911B1/en active Active
- 2019-12-24 TW TW108147446A patent/TW202039847A/zh unknown
-
2021
- 2021-06-27 IL IL284400A patent/IL284400A/en unknown
- 2021-07-26 ZA ZA2021/05281A patent/ZA202105281B/en unknown
-
2023
- 2023-05-12 US US18/316,698 patent/US12188018B2/en active Active
-
2024
- 2024-01-24 JP JP2024008844A patent/JP2024050676A/ja active Pending
- 2024-07-12 JP JP2024112452A patent/JP2024137967A/ja active Pending
- 2024-09-06 US US18/826,746 patent/US20250066783A1/en active Pending
- 2024-11-26 US US18/960,883 patent/US20250092398A1/en active Pending
-
2025
- 2025-10-06 AU AU2025242270A patent/AU2025242270A1/en active Pending
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