TW202039847A - 可用於基因編輯之多胜肽及使用方法 - Google Patents
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
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- C07—ORGANIC CHEMISTRY
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/80—Fusion polypeptide containing a DNA binding domain, e.g. Lacl or Tet-repressor
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
- C12Y305/04—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in cyclic amidines (3.5.4)
- C12Y305/04004—Adenosine deaminase (3.5.4.4)
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| US12188018B2 (en) | 2025-01-07 |
| EP3902911B1 (en) | 2023-12-13 |
| JP7572360B2 (ja) | 2024-10-23 |
| JP2024050676A (ja) | 2024-04-10 |
| EP3902911A2 (en) | 2021-11-03 |
| US20250066783A1 (en) | 2025-02-27 |
| IL312708A (en) | 2024-07-01 |
| SG11202106977PA (en) | 2021-07-29 |
| AU2019416108B2 (en) | 2025-10-23 |
| MX2021007835A (es) | 2021-08-11 |
| CN113631704A (zh) | 2021-11-09 |
| WO2020139783A3 (en) | 2020-07-23 |
| WO2020139783A2 (en) | 2020-07-02 |
| KR20210149686A (ko) | 2021-12-09 |
| EP4339286A2 (en) | 2024-03-20 |
| AU2025242270A1 (en) | 2025-10-30 |
| EP3902911C0 (en) | 2023-12-13 |
| US20220145296A1 (en) | 2022-05-12 |
| JP2024137967A (ja) | 2024-10-07 |
| EP4339286A3 (en) | 2024-08-28 |
| ES2970169T3 (es) | 2024-05-27 |
| AU2019416108A1 (en) | 2021-08-12 |
| IL284400A (en) | 2021-08-31 |
| JP2022516130A (ja) | 2022-02-24 |
| US20250092398A1 (en) | 2025-03-20 |
| NZ778392A (en) | 2025-11-28 |
| US20230272398A1 (en) | 2023-08-31 |
| BR112021012665A2 (pt) | 2021-11-03 |
| ZA202105281B (en) | 2024-05-30 |
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