JP2023504826A5 - - Google Patents
Info
- Publication number
- JP2023504826A5 JP2023504826A5 JP2022533406A JP2022533406A JP2023504826A5 JP 2023504826 A5 JP2023504826 A5 JP 2023504826A5 JP 2022533406 A JP2022533406 A JP 2022533406A JP 2022533406 A JP2022533406 A JP 2022533406A JP 2023504826 A5 JP2023504826 A5 JP 2023504826A5
- Authority
- JP
- Japan
- Prior art keywords
- recombinase
- sequence
- seq
- fusion protein
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19214152.1A EP3831939A1 (en) | 2019-12-06 | 2019-12-06 | Fusion of site-specific recombinases for efficient and specific genome editing |
| EP19214152.1 | 2019-12-06 | ||
| PCT/EP2020/084489 WO2021110846A1 (en) | 2019-12-06 | 2020-12-03 | Fusion of site-specific recombinases for efficient and specific genome editing |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023504826A JP2023504826A (ja) | 2023-02-07 |
| JP2023504826A5 true JP2023504826A5 (https=) | 2023-07-14 |
| JP7702149B2 JP7702149B2 (ja) | 2025-07-03 |
Family
ID=68808195
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022533406A Active JP7702149B2 (ja) | 2019-12-06 | 2020-12-03 | 効率的かつ特異的なゲノム編集のための部位特異的リコンビナーゼの融合 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20250243473A1 (https=) |
| EP (2) | EP3831939A1 (https=) |
| JP (1) | JP7702149B2 (https=) |
| CN (1) | CN115427558A (https=) |
| AU (1) | AU2020396214B2 (https=) |
| CA (1) | CA3163359A1 (https=) |
| MX (1) | MX2022006799A (https=) |
| WO (1) | WO2021110846A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI3638776T3 (fi) | 2017-06-14 | 2025-12-09 | Univ Dresden Tech | Menetelmiä ja välineitä genomien geneettiseen muokkaamiseen hyödyntäen suunnittelu-DNA:ta rekombinoivia entsyymejä |
| EP4433584A1 (en) * | 2021-11-15 | 2024-09-25 | Technische Universität Dresden | Site-specific recombinases for efficient and specific genome editing |
| US20250145973A1 (en) * | 2023-10-16 | 2025-05-08 | Technische Universität Dresden Körperschaft Des Öffentlichen Rechts | Conditioned dna modifying enzyme comprising heterologous dna binding domain |
| WO2026022363A1 (en) | 2024-07-25 | 2026-01-29 | Technische Universität Dresden Körperschaft Des Öffentlichen Rechts | Modifying nucleic acid sequences having asymmetric target sites |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5981830A (en) | 1997-05-30 | 1999-11-09 | Schering Aktiengesellschaft | Knockout mice and their progeny with a disrupted hepsin gene |
| ES2256972T3 (es) * | 1997-11-18 | 2006-07-16 | Pioneer Hi-Bred International, Inc. | Metodo novedoso para la integracion de un adn foraneo dentro de genomas de eucariotas. |
| GB0029375D0 (en) * | 2000-12-01 | 2001-01-17 | Total Fina Elf | Substrate linked directed evolution (slide) |
| US20060014264A1 (en) * | 2004-07-13 | 2006-01-19 | Stowers Institute For Medical Research | Cre/lox system with lox sites having an extended spacer region |
| EP1942192A1 (en) | 2007-01-08 | 2008-07-09 | Heinrich-Pette-Institut für experimentelle Virologie und Immunologie | Use of a tailored recombinase for the treatment of retroviral infections |
| EP2576798B1 (en) | 2010-05-27 | 2016-04-27 | Heinrich-Pette-Institut Leibniz-Institut für experimentelle Virologie-Stiftung bürgerlichen Rechts - | Tailored recombinase for recombining asymmetric target sites in a plurality of retrovirus strains |
| CN111254500B (zh) * | 2012-12-10 | 2024-01-23 | 分析生物科学有限公司 | 靶向基因组分析的方法 |
| EP2993229A1 (en) * | 2014-09-02 | 2016-03-09 | Heinrich-Pette-Institut Leibniz-Institut für experimentelle Virologie-Stiftung bürgerlichen Rechts - | Well-tolerated and highly specific tailored recombinase for recombining asymmetric target sites in a plurality of retrovirus strains |
| US10017832B2 (en) * | 2015-08-25 | 2018-07-10 | Washington University | Compositions and methods for site specific recombination at asymmetric sites |
| FI3638776T3 (fi) | 2017-06-14 | 2025-12-09 | Univ Dresden Tech | Menetelmiä ja välineitä genomien geneettiseen muokkaamiseen hyödyntäen suunnittelu-DNA:ta rekombinoivia entsyymejä |
| KR20250133994A (ko) * | 2018-05-09 | 2025-09-09 | 케로스 테라퓨틱스, 인크. | 액티빈 수용체 유형 iia 변이체 및 그의 사용 방법 |
-
2019
- 2019-12-06 EP EP19214152.1A patent/EP3831939A1/en not_active Withdrawn
-
2020
- 2020-12-03 WO PCT/EP2020/084489 patent/WO2021110846A1/en not_active Ceased
- 2020-12-03 CA CA3163359A patent/CA3163359A1/en active Pending
- 2020-12-03 AU AU2020396214A patent/AU2020396214B2/en active Active
- 2020-12-03 CN CN202080095838.7A patent/CN115427558A/zh active Pending
- 2020-12-03 MX MX2022006799A patent/MX2022006799A/es unknown
- 2020-12-03 US US17/780,136 patent/US20250243473A1/en active Pending
- 2020-12-03 EP EP20816214.9A patent/EP4069834A1/en active Pending
- 2020-12-03 JP JP2022533406A patent/JP7702149B2/ja active Active
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