JP2022522650A5 - - Google Patents

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Publication number
JP2022522650A5
JP2022522650A5 JP2021548244A JP2021548244A JP2022522650A5 JP 2022522650 A5 JP2022522650 A5 JP 2022522650A5 JP 2021548244 A JP2021548244 A JP 2021548244A JP 2021548244 A JP2021548244 A JP 2021548244A JP 2022522650 A5 JP2022522650 A5 JP 2022522650A5
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JP
Japan
Prior art keywords
crispr
activity
cas effector
polypeptide
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021548244A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022522650A (ja
JP7649748B2 (ja
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Application filed filed Critical
Priority claimed from PCT/US2020/021214 external-priority patent/WO2020181102A1/en
Publication of JP2022522650A publication Critical patent/JP2022522650A/ja
Publication of JP2022522650A5 publication Critical patent/JP2022522650A5/ja
Application granted granted Critical
Publication of JP7649748B2 publication Critical patent/JP7649748B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021548244A 2019-03-07 2020-03-05 Crispr-casエフェクターポリペプチド及びその使用方法 Active JP7649748B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962815179P 2019-03-07 2019-03-07
US62/815,179 2019-03-07
PCT/US2020/021214 WO2020181102A1 (en) 2019-03-07 2020-03-05 Crispr-cas effector polypeptides and methods of use thereof

Publications (3)

Publication Number Publication Date
JP2022522650A JP2022522650A (ja) 2022-04-20
JP2022522650A5 true JP2022522650A5 (https=) 2023-03-13
JP7649748B2 JP7649748B2 (ja) 2025-03-21

Family

ID=72338076

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021548244A Active JP7649748B2 (ja) 2019-03-07 2020-03-05 Crispr-casエフェクターポリペプチド及びその使用方法

Country Status (5)

Country Link
US (1) US12312614B2 (https=)
EP (1) EP3935155A4 (https=)
JP (1) JP7649748B2 (https=)
CN (1) CN114040971A (https=)
WO (1) WO2020181102A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015330699B2 (en) 2014-10-10 2021-12-02 Editas Medicine, Inc. Compositions and methods for promoting homology directed repair
US10660419B2 (en) * 2016-12-15 2020-05-26 Elc Management Llc Packaged skin treatment composition and method
EP3823633A4 (en) 2018-06-29 2023-05-03 Editas Medicine, Inc. SYNTHETIC LEAD MOLECULES, COMPOSITIONS AND METHODS RELATED THERETO
US10894812B1 (en) 2020-09-30 2021-01-19 Alpine Roads, Inc. Recombinant milk proteins
AU2021353004A1 (en) 2020-09-30 2023-04-13 Nobell Foods, Inc. Recombinant milk proteins and food compositions comprising the same
US10947552B1 (en) 2020-09-30 2021-03-16 Alpine Roads, Inc. Recombinant fusion proteins for producing milk proteins in plants
EP4347818A2 (en) 2021-06-01 2024-04-10 Arbor Biotechnologies, Inc. Gene editing systems comprising a crispr nuclease and uses thereof
WO2024006824A2 (en) * 2022-06-28 2024-01-04 Mammoth Biosciences, Inc. Effector proteins, compositions, systems and methods of use thereof
WO2024112957A1 (en) 2022-11-23 2024-05-30 Amber Bio Inc. Gene-modifying endonucleases
KR20250151430A (ko) 2023-02-15 2025-10-21 아버 바이오테크놀로지스, 인크. 스타스민 2(stmn2) 전사체에서 비정상적인 스플라이싱을 억제하는 유전자 편집 방법
WO2025171210A1 (en) 2024-02-09 2025-08-14 Arbor Biotechnologies, Inc. Compositions and methods for gene editing via homology-mediated end joining
WO2026015829A2 (en) 2024-07-12 2026-01-15 Arbor Biotechnologies, Inc. Small reverse transcriptases and gene editing systems comprising such
WO2026015832A2 (en) 2024-07-12 2026-01-15 Arbor Biotechnologies, Inc. Reverse transcriptases and gene editing systems comprising such
CN119372181A (zh) * 2024-09-14 2025-01-28 尧唐(南京)生物科技有限公司 一种核酸酶蛋白及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6605709B1 (en) * 1999-04-09 2003-08-12 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Proteus mirabilis for diagnostics and therapeutics
US20040029129A1 (en) * 2001-10-25 2004-02-12 Liangsu Wang Identification of essential genes in microorganisms
CA2537273A1 (en) * 2003-09-05 2005-03-17 Gtc Biotherapeutics, Inc. Method for the production of fusion proteins in transgenic mammal milk
CA2817256A1 (en) * 2010-11-12 2012-05-18 The General Hospital Corporation Polycomb-associated non-coding rnas
WO2015089427A1 (en) 2013-12-12 2015-06-18 The Broad Institute Inc. Crispr-cas systems and methods for altering expression of gene products, structural information and inducible modular cas enzymes
US9790490B2 (en) * 2015-06-18 2017-10-17 The Broad Institute Inc. CRISPR enzymes and systems
AU2016380351B2 (en) * 2015-12-29 2023-04-06 Monsanto Technology Llc Novel CRISPR-associated transposases and uses thereof
AU2017257274B2 (en) * 2016-04-19 2023-07-13 Massachusetts Institute Of Technology Novel CRISPR enzymes and systems
US11692184B2 (en) 2017-05-16 2023-07-04 The Regents Of The University Of California Thermostable RNA-guided endonucleases and methods of use thereof
GB201712733D0 (en) * 2017-08-08 2017-09-20 Snipr Tech Ltd Methods & cells

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