JP2023505600A5 - - Google Patents
Info
- Publication number
- JP2023505600A5 JP2023505600A5 JP2022538683A JP2022538683A JP2023505600A5 JP 2023505600 A5 JP2023505600 A5 JP 2023505600A5 JP 2022538683 A JP2022538683 A JP 2022538683A JP 2022538683 A JP2022538683 A JP 2022538683A JP 2023505600 A5 JP2023505600 A5 JP 2023505600A5
- Authority
- JP
- Japan
- Prior art keywords
- crispr
- type
- nucleic acid
- cas effector
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962930836P | 2019-11-05 | 2019-11-05 | |
| US62/930,836 | 2019-11-05 | ||
| PCT/US2020/059045 WO2021092130A1 (en) | 2019-11-05 | 2020-11-05 | Compositions and methods for rna-encoded dna-replacement of alleles |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023505600A JP2023505600A (ja) | 2023-02-09 |
| JP2023505600A5 true JP2023505600A5 (https=) | 2023-09-20 |
| JP7785002B2 JP7785002B2 (ja) | 2025-12-12 |
Family
ID=75687119
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022538683A Active JP7785002B2 (ja) | 2019-11-05 | 2020-11-05 | 対立遺伝子のｒｎａにコードされたｄｎａの置換のための組成物および方法 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US11926834B2 (https=) |
| EP (1) | EP4054621A4 (https=) |
| JP (1) | JP7785002B2 (https=) |
| KR (1) | KR20220110748A (https=) |
| CN (1) | CN114901302A (https=) |
| AU (1) | AU2020380319A1 (https=) |
| BR (1) | BR112022008415A2 (https=) |
| CA (1) | CA3160186A1 (https=) |
| CL (1) | CL2022001145A1 (https=) |
| IL (1) | IL292434A (https=) |
| MX (1) | MX2022005328A (https=) |
| NZ (1) | NZ787446A (https=) |
| WO (1) | WO2021092130A1 (https=) |
| ZA (1) | ZA202204756B (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015330699B2 (en) | 2014-10-10 | 2021-12-02 | Editas Medicine, Inc. | Compositions and methods for promoting homology directed repair |
| WO2020191233A1 (en) | 2019-03-19 | 2020-09-24 | The Broad Institute, Inc. | Methods and compositions for editing nucleotide sequences |
| AU2020369599A1 (en) | 2019-10-23 | 2022-05-12 | Monsanto Technology Llc | Compositions and methods for RNA-templated editing in plants |
| CA3160186A1 (en) | 2019-11-05 | 2021-05-14 | Pairwise Plants Services, Inc. | Compositions and methods for rna-encoded dna-replacement of alleles |
| IL297761A (en) | 2020-05-08 | 2022-12-01 | Broad Inst Inc | Methods and compositions for simultaneously editing two helices of a designated double-helix nucleotide sequence |
| US20220145334A1 (en) * | 2020-11-06 | 2022-05-12 | Pairwise Plants Services, Inc. | Compositions and methods for rna-encoded dna-replacement of alleles |
| EP4347818A2 (en) * | 2021-06-01 | 2024-04-10 | Arbor Biotechnologies, Inc. | Gene editing systems comprising a crispr nuclease and uses thereof |
| US20220403475A1 (en) | 2021-06-14 | 2022-12-22 | Pairwise Plants Services, Inc. | Reporter constructs, compositions comprising the same, and methods of use thereof |
| AU2022343268A1 (en) | 2021-09-08 | 2024-03-28 | Flagship Pioneering Innovations Vi, Llc | Methods and compositions for modulating a genome |
| WO2023049728A1 (en) | 2021-09-21 | 2023-03-30 | Pairwise Plants Services, Inc. | Color-based and/or visual methods for identifying the presence of a transgene and compositions and constructs relating to the same |
| EP4596696A3 (en) | 2021-09-28 | 2025-08-27 | Acrigen Biosciences | Compositions and methods for nucleic acid modifications |
| WO2023102329A2 (en) * | 2021-11-30 | 2023-06-08 | Mammoth Biosciences, Inc. | Effector proteins and uses thereof |
| CN114317492A (zh) * | 2021-12-06 | 2022-04-12 | 北京大学 | 一种改造的人工核酸酶系统及其应用 |
| CN116064512A (zh) * | 2022-07-15 | 2023-05-05 | 山西大学 | 一种改进的引导编辑系统及其应用 |
| JP2025525569A (ja) * | 2022-07-18 | 2025-08-05 | レナゲード セラピューティクス マネージメント インコーポレイテッド | 遺伝子編集成分、システム、及び使用方法 |
| US12264328B2 (en) | 2022-07-18 | 2025-04-01 | ReNAgade Therapeutics Management, Inc. | Gene editing components, systems, and methods of use |
| CA3268411A1 (en) * | 2022-09-23 | 2024-03-28 | Flagship Pioneering Innovations Vi, Llc | METHODS FOR ENRICHING TARGET NUCLEIC ACID SEQUENCES |
| WO2024096790A1 (en) * | 2022-10-31 | 2024-05-10 | Soledits Ab | Modular crispr system |
| EP4627083A1 (en) * | 2022-11-30 | 2025-10-08 | Arbor Biotechnologies, Inc. | Reverse transcriptase-mediated genetic editing of transthyretin (ttr) and uses thereof |
| EP4630542A2 (en) * | 2022-12-09 | 2025-10-15 | Metagenomi, Inc. | Retrotransposon compositions and methods of use |
| EP4634375A2 (en) | 2022-12-16 | 2025-10-22 | Pairwise Plants Services, Inc. | Fusion proteins comprising a cas12a polypeptide and an intein and methods of use therof |
| US20240271109A1 (en) | 2022-12-21 | 2024-08-15 | Pairwise Plants Services, Inc. | Engineered proteins and methods of use thereof |
| AU2024239266A1 (en) | 2023-03-20 | 2025-09-25 | Pioneer Hi-Bred International, Inc. | Cas polypeptides with altered pam recognition |
| AU2024348958A1 (en) | 2023-09-26 | 2026-04-02 | Pairwise Plants Services, Inc. | Fusion proteins, compositions comprising the same, and methods of use thereof |
| AU2024357941A1 (en) | 2023-10-09 | 2026-04-02 | Pairwise Plants Services, Inc. | Circular permutants, compositions comprising the same, and methods of use thereof |
| WO2026019871A1 (en) | 2024-07-17 | 2026-01-22 | Pairwise Plants Services, Inc. | Engineered cytidine deaminases |
| US20260022361A1 (en) | 2024-07-17 | 2026-01-22 | Pairwise Plants Services, Inc. | Engineered proteins and methods of use thereof |
| US12297441B1 (en) | 2024-09-11 | 2025-05-13 | Pairwise Plants Services, Inc. | Methods and compositions for modifying endocarp structure in Rubus plants |
| WO2026085100A1 (en) | 2024-10-15 | 2026-04-23 | Pairwise Plants Services, Inc. | Methods for high density planting of rubus plants comprising a mutation in the terminal flower (tfl) gene |
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| UA48104C2 (uk) | 1991-10-04 | 2002-08-15 | Новартіс Аг | Фрагмент днк, який містить послідовність,що кодує інсектицидний протеїн, оптимізовану для кукурудзи,фрагмент днк, який забезпечує направлену бажану для серцевини стебла експресію зв'язаного з нею структурного гена в рослині, фрагмент днк, який забезпечує специфічну для пилку експресію зв`язаного з нею структурного гена в рослині, рекомбінантна молекула днк, спосіб одержання оптимізованої для кукурудзи кодуючої послідовності інсектицидного протеїну, спосіб захисту рослин кукурудзи щонайменше від однієї комахи-шкідника |
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| AU2013335451C1 (en) * | 2012-10-23 | 2024-07-04 | Toolgen Incorporated | Composition for cleaving a target DNA comprising a guide RNA specific for the target DNA and Cas protein-encoding nucleic acid or Cas protein, and use thereof |
| WO2014186686A2 (en) * | 2013-05-17 | 2014-11-20 | Two Blades Foundation | Targeted mutagenesis and genome engineering in plants using rna-guided cas nucleases |
| CN120574876A (zh) | 2013-08-22 | 2025-09-02 | 纳幕尔杜邦公司 | 使用向导rna/cas内切核酸酶系统的植物基因组修饰及其使用方法 |
| AU2015234204A1 (en) | 2014-03-20 | 2016-10-06 | Universite Laval | CRISPR-based methods and products for increasing frataxin levels and uses thereof |
| US20170219596A1 (en) | 2014-07-14 | 2017-08-03 | The Regents Of The University Of California | A protein tagging system for in vivo single molecule imaging and control of gene transcription |
| KR102357893B1 (ko) | 2014-08-05 | 2022-02-04 | 맵퀘스트 에스아 | Pd-1 에 결합하는 면역학적 시약 |
| EP4464338A3 (en) * | 2014-11-07 | 2025-02-12 | Editas Medicine, Inc. | Systems for improving crispr/cas-mediated genome-editing |
| KR102888521B1 (ko) * | 2015-04-06 | 2025-11-19 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | Crispr/cas-매개 유전자 조절을 위한 화학적으로 변형된 가이드 rna |
| US20160362667A1 (en) * | 2015-06-10 | 2016-12-15 | Caribou Biosciences, Inc. | CRISPR-Cas Compositions and Methods |
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| CN108473981B (zh) | 2015-12-04 | 2022-04-12 | 卡里布生物科学公司 | 工程化靶向核酸的核酸 |
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| AU2017257274B2 (en) | 2016-04-19 | 2023-07-13 | Massachusetts Institute Of Technology | Novel CRISPR enzymes and systems |
| EP3463484B1 (en) * | 2016-05-27 | 2026-01-07 | The Regents of the University of California | Methods and compositions for targeting rna polymerases and non-coding rna biogenesis to specific loci |
| EP3464594A1 (en) | 2016-06-01 | 2019-04-10 | Kws Saat Se | Hybrid nucleic acid sequences for genome engineering |
| CN109790527A (zh) | 2016-07-26 | 2019-05-21 | 通用医疗公司 | 普氏菌属和弗朗西斯氏菌属的CRISPR1(Cpf1)的变体 |
| ES2985812T3 (es) | 2016-09-09 | 2024-11-07 | The Board Of Trustees Of The Leland Stanfordjunior Univ | Edición genómica de precisión de alto rendimiento |
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| US11591589B2 (en) | 2017-04-21 | 2023-02-28 | The General Hospital Corporation | Variants of Cpf1 (Cas12a) with altered PAM specificity |
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| EP3728589A4 (en) * | 2017-12-22 | 2021-11-03 | G+Flas Life Sciences | CHEMICAL GENOMIC ENGINEERING MOLECULES AND PROCESSES |
| US11268092B2 (en) | 2018-01-12 | 2022-03-08 | GenEdit, Inc. | Structure-engineered guide RNA |
| WO2020191233A1 (en) * | 2019-03-19 | 2020-09-24 | The Broad Institute, Inc. | Methods and compositions for editing nucleotide sequences |
| AU2020369599A1 (en) | 2019-10-23 | 2022-05-12 | Monsanto Technology Llc | Compositions and methods for RNA-templated editing in plants |
| CA3160186A1 (en) | 2019-11-05 | 2021-05-14 | Pairwise Plants Services, Inc. | Compositions and methods for rna-encoded dna-replacement of alleles |
| US20220145334A1 (en) | 2020-11-06 | 2022-05-12 | Pairwise Plants Services, Inc. | Compositions and methods for rna-encoded dna-replacement of alleles |
-
2020
- 2020-11-05 CA CA3160186A patent/CA3160186A1/en active Pending
- 2020-11-05 US US17/090,334 patent/US11926834B2/en active Active
- 2020-11-05 NZ NZ787446A patent/NZ787446A/en unknown
- 2020-11-05 EP EP20884787.1A patent/EP4054621A4/en active Pending
- 2020-11-05 WO PCT/US2020/059045 patent/WO2021092130A1/en not_active Ceased
- 2020-11-05 BR BR112022008415A patent/BR112022008415A2/pt unknown
- 2020-11-05 IL IL292434A patent/IL292434A/en unknown
- 2020-11-05 AU AU2020380319A patent/AU2020380319A1/en active Pending
- 2020-11-05 CN CN202080084407.0A patent/CN114901302A/zh active Pending
- 2020-11-05 JP JP2022538683A patent/JP7785002B2/ja active Active
- 2020-11-05 MX MX2022005328A patent/MX2022005328A/es unknown
- 2020-11-05 KR KR1020227018853A patent/KR20220110748A/ko active Pending
-
2022
- 2022-04-28 ZA ZA2022/04756A patent/ZA202204756B/en unknown
- 2022-05-03 CL CL2022001145A patent/CL2022001145A1/es unknown
-
2024
- 2024-01-26 US US18/423,374 patent/US20240167045A1/en active Pending
- 2024-01-26 US US18/423,378 patent/US20240158804A1/en active Pending
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