TW202346583A - Rna引導核酸酶、其活性片段與變體，及使用方法 - Google Patents

Rna引導核酸酶、其活性片段與變體，及使用方法 Download PDF

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TW202346583A
TW202346583A TW112103115A TW112103115A TW202346583A TW 202346583 A TW202346583 A TW 202346583A TW 112103115 A TW112103115 A TW 112103115A TW 112103115 A TW112103115 A TW 112103115A TW 202346583 A TW202346583 A TW 202346583A
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sequence
seq
sequence identity
rgn
tracrrna
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TW112103115A
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Chinese (zh)
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貢詹 Ｈ 艾莉亞
麥可 柯伊雷
亞歷山卓 布萊勒 克羅雷
泰德 Ｄ 艾力奇
何塞 Ｓ 派克
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美商生命編輯治療學公司
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TW112103115A 2022-01-24 2023-01-30 Rna引導核酸酶、其活性片段與變體，及使用方法 TW202346583A (zh)

Applications Claiming Priority (4)

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US202263302271P 2022-01-24 2022-01-24
US63/302,271 2022-01-24
US202263386061P 2022-12-05 2022-12-05
US63/386,061 2022-12-05

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TW202346583A true TW202346583A (zh) 2023-12-01

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US (4) US12435325B2 (https=)
EP (2) EP4466349A1 (https=)
JP (1) JP2025504898A (https=)
KR (1) KR20250008537A (https=)
CN (1) CN119317713A (https=)
AU (1) AU2023208961A1 (https=)
CA (1) CA3243220A1 (https=)
IL (1) IL314488A (https=)
MX (1) MX2024009148A (https=)
TW (1) TW202346583A (https=)
WO (1) WO2023139557A1 (https=)

Families Citing this family (6)

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EP4612284A2 (en) 2022-11-04 2025-09-10 Life Edit Therapeutics, Inc. Evolved adenine deaminases and rna-guided nuclease fusion proteins with internal insertion sites and methods of use
CA3277009A1 (en) * 2022-12-16 2024-06-20 Life Edit Therapeutics, Inc. RNA GUIDELINES TARGETING THE TRAC GENE AND METHODS OF USE
WO2024178397A2 (en) 2023-02-24 2024-08-29 Elevatebio Technologies, Inc. Modified immune effector cells and methods of use
WO2025022367A2 (en) 2023-07-27 2025-01-30 Life Edit Therapeutics, Inc. Rna-guided nucleases and active fragments and variants thereof and methods of use
TW202546224A (zh) 2024-02-12 2025-12-01 美商生命編輯治療學公司 新穎的ｒｎａ引導之核酸酶及用於聚合酶編輯之蛋白質
WO2026003754A1 (en) 2024-06-25 2026-01-02 Life Edit Therapeutics, Inc. Novel reverse transcriptases and uses thereof

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