JP2025106480A5 - - Google Patents
Info
- Publication number
- JP2025106480A5 JP2025106480A5 JP2025064597A JP2025064597A JP2025106480A5 JP 2025106480 A5 JP2025106480 A5 JP 2025106480A5 JP 2025064597 A JP2025064597 A JP 2025064597A JP 2025064597 A JP2025064597 A JP 2025064597A JP 2025106480 A5 JP2025106480 A5 JP 2025106480A5
- Authority
- JP
- Japan
- Prior art keywords
- micelle
- units
- moiety
- positively charged
- portion comprises
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962867097P | 2019-06-26 | 2019-06-26 | |
| US62/867,097 | 2019-06-26 | ||
| US202063043693P | 2020-06-24 | 2020-06-24 | |
| US63/043,693 | 2020-06-24 | ||
| JP2021577297A JP7665540B2 (ja) | 2019-06-26 | 2020-06-26 | ミセルナノ粒子及びその使用 |
| PCT/IB2020/056093 WO2020261227A1 (en) | 2019-06-26 | 2020-06-26 | Micellar nanoparticles and uses thereof |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021577297A Division JP7665540B2 (ja) | 2019-06-26 | 2020-06-26 | ミセルナノ粒子及びその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2025106480A JP2025106480A (ja) | 2025-07-15 |
| JP2025106480A5 true JP2025106480A5 (https=) | 2025-07-25 |
Family
ID=74060198
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021577297A Active JP7665540B2 (ja) | 2019-06-26 | 2020-06-26 | ミセルナノ粒子及びその使用 |
| JP2025064597A Pending JP2025106480A (ja) | 2019-06-26 | 2025-04-09 | ミセルナノ粒子及びその使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021577297A Active JP7665540B2 (ja) | 2019-06-26 | 2020-06-26 | ミセルナノ粒子及びその使用 |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20220257790A1 (https=) |
| EP (2) | EP4603589A3 (https=) |
| JP (2) | JP7665540B2 (https=) |
| KR (2) | KR102658962B1 (https=) |
| CN (1) | CN114514038B (https=) |
| AU (1) | AU2020303447A1 (https=) |
| BR (1) | BR112021026365A2 (https=) |
| CA (1) | CA3144333A1 (https=) |
| CO (1) | CO2022000316A2 (https=) |
| DK (1) | DK3990028T3 (https=) |
| IL (1) | IL289258A (https=) |
| MX (1) | MX2022000045A (https=) |
| PE (1) | PE20220902A1 (https=) |
| WO (1) | WO2020261227A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10844380B1 (en) | 2019-06-17 | 2020-11-24 | Biorchestra Co., Ltd. | Uses for prevention or treatment of brain diseases using microrna |
| WO2021156833A1 (en) * | 2020-02-07 | 2021-08-12 | Biorchestra Co., Ltd. | Use of mirna-485 inhibitors for treating tauopathy |
| US11761874B2 (en) * | 2020-05-15 | 2023-09-19 | Saudi Arabian Oil Company | CMC-based method for surfactant concentration determination |
| KR20230084499A (ko) * | 2020-10-09 | 2023-06-13 | 고쿠리츠다이가쿠호우진 도쿄다이가쿠 | 니코틴아미드 내포 미셀, 및 니코틴아미드 내포 미셀을 포함하는 임신 고혈압 증후군 치료용 조성물 |
| CA3200622A1 (en) * | 2020-12-30 | 2022-07-07 | Jin-Hyeob RYU | Micellar nanoparticles and uses thereof |
| CN116963722A (zh) * | 2020-12-30 | 2023-10-27 | 生物欧赛加有限责任公司 | 胶束纳米粒子及其用途 |
| US20250313835A1 (en) * | 2022-07-07 | 2025-10-09 | Biorchestra Co., Ltd. | Micellar nanoparticles and uses thereof |
| CN115721608A (zh) * | 2022-11-29 | 2023-03-03 | 陕西科技大学 | 一种靶向温度敏感性聚合物胶束、制备方法及应用 |
| WO2024228119A1 (en) * | 2023-05-01 | 2024-11-07 | Biorchestra Co., Ltd. | Mirna-485 inhibitors |
| WO2024228118A1 (en) * | 2023-05-01 | 2024-11-07 | Biorchestra Co., Ltd. | Mirna-485 inhibitors |
| WO2025149946A1 (en) * | 2024-01-10 | 2025-07-17 | Biorchestra Co., Ltd. | Micellar nanoparticles and uses thereof |
Family Cites Families (46)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5219564A (en) * | 1990-07-06 | 1993-06-15 | Enzon, Inc. | Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon |
| US20040259247A1 (en) | 2000-12-01 | 2004-12-23 | Thomas Tuschl | Rna interference mediating small rna molecules |
| WO2004002455A1 (en) * | 2002-06-26 | 2004-01-08 | Medigene Oncology Gmbh | Novel method of stabilizing diagnostic and therapeutic compounds in a cationic carrier system |
| US7683036B2 (en) | 2003-07-31 | 2010-03-23 | Regulus Therapeutics Inc. | Oligomeric compounds and compositions for use in modulation of small non-coding RNAs |
| US20050142581A1 (en) | 2003-09-04 | 2005-06-30 | Griffey Richard H. | Microrna as ligands and target molecules |
| EP1718667B1 (en) | 2004-02-23 | 2013-01-09 | Genentech, Inc. | Heterocyclic self-immolative linkers and conjugates |
| US20080213891A1 (en) | 2004-07-21 | 2008-09-04 | Alnylam Pharmaceuticals, Inc. | RNAi Agents Comprising Universal Nucleobases |
| AU2005328382C1 (en) | 2004-07-21 | 2013-01-24 | Alnylam Pharmaceuticals, Inc. | Oligonucleotides comprising a modified or non-natural nucleobase |
| CA2574603C (en) | 2004-08-04 | 2014-11-04 | Alnylam Pharmaceuticals, Inc. | Oligonucleotides comprising a ligand tethered to a modified or non-natural nucleobase |
| WO2007021896A2 (en) | 2005-08-10 | 2007-02-22 | Alnylam Pharmaceuticals, Inc. | Chemically modified oligonucleotides for use in modulating micro rna and uses thereof |
| US20070213292A1 (en) | 2005-08-10 | 2007-09-13 | The Rockefeller University | Chemically modified oligonucleotides for use in modulating micro RNA and uses thereof |
| WO2007027894A2 (en) | 2005-08-29 | 2007-03-08 | Isis Pharmaceuticals, Inc. | Antisense compounds having enhanced anti-microrna activity |
| CA2620856C (en) | 2005-08-29 | 2017-11-28 | Isis Pharmaceuticals, Inc. | Methods for use in modulating mir-122a |
| EP1984499B1 (en) | 2006-01-27 | 2015-05-27 | Isis Pharmaceuticals, Inc. | Oligomeric compounds and compositions for the use in modulation of micrornas |
| EP2666859B1 (en) | 2006-04-03 | 2019-01-02 | Roche Innovation Center Copenhagen A/S | Pharmaceutical composition comprising anti-mirna antisense oligonucleotides |
| CA2648132C (en) | 2006-04-03 | 2019-05-28 | Santaris Pharma A/S | Pharmaceutical composition comprising anti-mirna antisense oligonucleotides |
| WO2008046911A2 (en) | 2006-10-20 | 2008-04-24 | Exiqon A/S | Novel human micrornas associated with cancer |
| US20090137504A1 (en) | 2006-12-21 | 2009-05-28 | Soren Morgenthaler Echwald | Microrna target site blocking oligos and uses thereof |
| WO2008113832A2 (en) | 2007-03-22 | 2008-09-25 | Santaris Pharma A/S | SHORT RNA ANTAGONIST COMPOUNDS FOR THE MODULATION OF TARGET mRNA |
| EP2623599B1 (en) | 2007-10-04 | 2019-01-02 | Roche Innovation Center Copenhagen A/S | Micromirs |
| US20090156459A1 (en) * | 2007-11-16 | 2009-06-18 | Pharmain Corporation | Cationic-Core Carrier Compositions for Delivery of Therapeutic Agents, Methods of Making and Using the Same |
| US8541435B2 (en) * | 2008-07-11 | 2013-09-24 | Uday Saxena | Niacin compositions for reduction of amyloid beta peptide 42 (abeta 42) production and for treatment of Alzheimer's disease (AD) |
| JP5622254B2 (ja) * | 2009-03-31 | 2014-11-12 | 国立大学法人東京大学 | 二本鎖リボ核酸ポリイオンコンプレックス |
| ES2599979T3 (es) | 2009-04-24 | 2017-02-06 | Roche Innovation Center Copenhagen A/S | Composiciones farmacéuticas para el tratamiento de pacientes de VHC que no responden al interferón |
| CN102573913B (zh) * | 2009-07-31 | 2014-06-18 | 阿森迪斯药物股份有限公司 | 可生物降解的基于聚乙二醇的水不溶性水凝胶 |
| CA2773737C (en) * | 2009-09-09 | 2021-11-16 | Pharmain Corporation | Anionic-core composition for delivery of therapeutic agents, and methods of making and using the same |
| US20120005765A1 (en) * | 2010-07-01 | 2012-01-05 | Saint Louis University | Animal model for parkinson's disease |
| BR112013006686A2 (pt) | 2010-09-24 | 2017-11-14 | Zoetis Llc | isoxazolina oximas como agentes antiparasitários |
| EP2741780A1 (en) * | 2011-08-10 | 2014-06-18 | Ludwig-Maximilians-Universität München | Method for the controlled intracellular delivery of nucleic acids |
| JP6646578B2 (ja) * | 2013-12-05 | 2020-02-14 | ウー, ニエンWU, Nian | 薬物転送技術のための高分子−炭水化物共役体 |
| KR20170003527A (ko) * | 2014-02-24 | 2017-01-09 | 유리젠 파마슈티컬스, 인코포레이티드 | 경구 투여용 펜토산 폴리설페이트 염의 조성물 |
| US20180334732A1 (en) * | 2014-11-25 | 2018-11-22 | Drexel University | Compositions and methods for hiv quasi-species excision from hiv-1-infected patients |
| CN108289906B (zh) * | 2015-11-19 | 2022-03-11 | 公立大学法人名古屋市立大学 | 抗肿瘤性药物递送制剂 |
| WO2017212007A1 (en) * | 2016-06-09 | 2017-12-14 | Curevac Ag | Cationic carriers for nucleic acid delivery |
| WO2018053316A1 (en) | 2016-09-15 | 2018-03-22 | The Regents Of The University Of California | Improved hybrid telodendrimers |
| RU2016146594A (ru) * | 2016-11-28 | 2018-05-28 | Общество С Ограниченной Ответственностью "Биофарм-Меморейн" | Средство для лечения деменции различной этиологии |
| CN110582301A (zh) | 2016-12-14 | 2019-12-17 | 利甘达尔股份有限公司 | 用于核酸和蛋白质有效负载递送的方法和组合物 |
| WO2018139759A1 (ko) * | 2017-01-26 | 2018-08-02 | 주식회사 바이오오케스트라 | 마이크로 rna를 이용한 알츠하이머병 진단방법 |
| US11123304B2 (en) | 2017-02-03 | 2021-09-21 | The Brigham And Women's Hospital, Inc. | Nanoparticles having poly(ester amide) polymer cores as drug delivery vehicles |
| CN110156971A (zh) | 2018-02-13 | 2019-08-23 | 上海时莱生物技术有限公司 | 一种两亲性嵌段共聚物及其制备方法和纳米胶束载药系统 |
| US11857634B2 (en) | 2018-04-20 | 2024-01-02 | University of Pittsburgh—of the Commonwealth System of Higher Education | Cationic amphiphilic polymers for codelivery of hydrophobic agents and nucleic acids |
| CN111632153B (zh) | 2020-06-23 | 2023-02-24 | 宁夏医科大学 | 一种化学基因药物共载的靶向纳米递药系统及其制备方法 |
| CA3200622A1 (en) | 2020-12-30 | 2022-07-07 | Jin-Hyeob RYU | Micellar nanoparticles and uses thereof |
| JP2024503303A (ja) | 2020-12-30 | 2024-01-25 | バイオーケストラ カンパニー, リミテッド | ミセルナノ粒子及びその使用 |
-
2020
- 2020-06-26 US US17/622,518 patent/US20220257790A1/en active Pending
- 2020-06-26 JP JP2021577297A patent/JP7665540B2/ja active Active
- 2020-06-26 EP EP25172311.0A patent/EP4603589A3/en active Pending
- 2020-06-26 BR BR112021026365A patent/BR112021026365A2/pt unknown
- 2020-06-26 DK DK20831649.7T patent/DK3990028T3/da active
- 2020-06-26 EP EP20831649.7A patent/EP3990028B1/en active Active
- 2020-06-26 MX MX2022000045A patent/MX2022000045A/es unknown
- 2020-06-26 WO PCT/IB2020/056093 patent/WO2020261227A1/en not_active Ceased
- 2020-06-26 CN CN202080057979.XA patent/CN114514038B/zh active Active
- 2020-06-26 PE PE2021002229A patent/PE20220902A1/es unknown
- 2020-06-26 AU AU2020303447A patent/AU2020303447A1/en not_active Abandoned
- 2020-06-26 CA CA3144333A patent/CA3144333A1/en active Pending
- 2020-06-26 KR KR1020227002029A patent/KR102658962B1/ko active Active
- 2020-06-26 KR KR1020247009114A patent/KR20240039234A/ko not_active Ceased
-
2021
- 2021-10-15 US US17/502,923 patent/US11839624B2/en active Active
- 2021-12-22 IL IL289258A patent/IL289258A/en unknown
-
2022
- 2022-01-17 CO CONC2022/0000316A patent/CO2022000316A2/es unknown
-
2023
- 2023-11-07 US US18/503,748 patent/US20240173348A1/en active Pending
-
2025
- 2025-04-09 JP JP2025064597A patent/JP2025106480A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2025106480A5 (https=) | ||
| US11020487B2 (en) | Compositions for introducing nucelic acid into cells | |
| AU2014300980B2 (en) | Compositions for introducing RNA into cells | |
| JP2025126919A5 (https=) | ||
| JP2023123491A5 (https=) | ||
| CN109072238B (zh) | 使用靶向结缔组织生长因子的rna复合物治疗特发性肺纤维化 | |
| US20210121580A1 (en) | Functionalized DNA Dendrimers For Gene Delivery To Cells | |
| US12478684B2 (en) | Oligonucleotide-polymer miktoarm conjugates and methods of use | |
| Do et al. | Difatty acyl-conjugated linear and cyclic peptides for siRNA delivery | |
| CN114317545B (zh) | 一种核酸适体及其应用 | |
| CN114901823A (zh) | 诱导外显子50的跳读的反义核酸 | |
| WO2024147020A1 (en) | Polymersomes for delivery of nucleic acid cargoes | |
| US9579394B2 (en) | Polyanion nanocomplexes for therapeutic applications | |
| JPWO2020261227A5 (https=) | ||
| IL316806A (en) | Compositions and methods for treating monogenic neurodevelopmental disorder | |
| KR20240040112A (ko) | 방법 | |
| WO2022219409A2 (en) | Compositions containing nucleic acid nanoparticles and processes related to alteration of their physicochemical characteristics | |
| KR20240072931A (ko) | 히스티딘을 포함하는 지질 나노입자 및 그 제조방법 | |
| TW202241461A (zh) | 微胞奈米粒子及其用途 | |
| Nomani et al. | Poly (amido amine) dendrimer silences the expression of epidermal growth factor receptor and p53 gene in vitro | |
| US20200347385A1 (en) | METHOD FOR mRNA STABILIZATION | |
| Wu et al. | Unlocking the potential of RNA-based therapeutics in the lung: current status and future | |
| Sarkar et al. | Recent developments in the delivery of peptide nucleic acids (PNAs) | |
| JP2026068029A (ja) | 一本鎖核酸及びその用途 | |
| JPWO2022144811A5 (https=) |