JP2023553697A5 - - Google Patents

Info

Publication number
JP2023553697A5
JP2023553697A5 JP2023536866A JP2023536866A JP2023553697A5 JP 2023553697 A5 JP2023553697 A5 JP 2023553697A5 JP 2023536866 A JP2023536866 A JP 2023536866A JP 2023536866 A JP2023536866 A JP 2023536866A JP 2023553697 A5 JP2023553697 A5 JP 2023553697A5
Authority
JP
Japan
Prior art keywords
amino acid
seq
acid sequence
isvd
specifically binds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2023536866A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023553697A (ja
JP7820383B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/086559 external-priority patent/WO2022129560A1/en
Publication of JP2023553697A publication Critical patent/JP2023553697A/ja
Publication of JP2023553697A5 publication Critical patent/JP2023553697A5/ja
Application granted granted Critical
Publication of JP7820383B2 publication Critical patent/JP7820383B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2023536866A 2020-12-18 2021-12-17 グリピカン-3およびt細胞受容体を標的とする免疫グロブリン単一可変ドメインを含むポリペプチド Active JP7820383B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063127224P 2020-12-18 2020-12-18
US63/127,224 2020-12-18
EP20306633.7 2020-12-21
EP20306633 2020-12-21
PCT/EP2021/086559 WO2022129560A1 (en) 2020-12-18 2021-12-17 Polypeptides comprising immunoglobulin single variable domains targeting glypican-3 and t cell receptor

Publications (3)

Publication Number Publication Date
JP2023553697A JP2023553697A (ja) 2023-12-25
JP2023553697A5 true JP2023553697A5 (https=) 2024-10-25
JP7820383B2 JP7820383B2 (ja) 2026-02-25

Family

ID=79283159

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023536866A Active JP7820383B2 (ja) 2020-12-18 2021-12-17 グリピカン-3およびt細胞受容体を標的とする免疫グロブリン単一可変ドメインを含むポリペプチド

Country Status (11)

Country Link
US (2) US11932702B2 (https=)
EP (1) EP4262985A1 (https=)
JP (1) JP7820383B2 (https=)
KR (1) KR20230123495A (https=)
AU (1) AU2021399955A1 (https=)
CA (1) CA3205422A1 (https=)
CO (1) CO2023009231A2 (https=)
IL (1) IL303783A (https=)
MX (1) MX2023007308A (https=)
TW (1) TW202241947A (https=)
WO (1) WO2022129560A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201805064SA (en) * 2011-06-23 2018-07-30 Ablynx Nv Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains
LT3611192T (lt) * 2015-05-13 2025-06-25 Ablynx N.V. T ląstelių rekrutingo polipeptidai tcr alfa/beta reaktyvumo pagrindu
AU2023290487A1 (en) * 2022-06-14 2025-01-30 Ablynx Nv Immunoglobulin single variable domains targeting t cell receptor
WO2024118866A1 (en) * 2022-12-01 2024-06-06 Modernatx, Inc. Gpc3-specific antibodies, binding domains, and related proteins and uses thereof
AR131494A1 (es) 2022-12-23 2025-03-26 Ablynx Nv Vehículos de conjugación a base de proteína
WO2025051767A1 (en) 2023-09-04 2025-03-13 Sanofi Polypeptides for use in the treatment of glypican-3-expressing tumours
TW202532432A (zh) * 2023-09-22 2025-08-16 比利時商艾伯霖克斯公司 二及多價白蛋白結合劑
US20260007757A1 (en) 2024-06-18 2026-01-08 Ablynx Nv Antibody-recruiting molecules

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1621554T4 (da) 1992-08-21 2012-12-17 Univ Bruxelles Immunoglobuliner blottet for lette kæder
EP0739981A1 (en) 1995-04-25 1996-10-30 Vrije Universiteit Brussel Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes
DK1027439T3 (da) 1997-10-27 2010-05-10 Bac Ip Bv Multivalente antigenbindende proteiner
WO2004041863A2 (en) 2002-11-08 2004-05-21 Ablynx N.V. Single domain antibodies directed against interferon- gamma and uses therefor
SI1674111T1 (sl) * 2004-07-09 2011-02-28 Chugai Pharmaceutical Co Ltd Protitelo proti glipikanu 3
US8188223B2 (en) 2005-05-18 2012-05-29 Ablynx N.V. Serum albumin binding proteins
AU2007237501A1 (en) 2006-04-14 2007-10-25 Ablynx N.V. DP-78-like nanobodies
WO2008020079A1 (en) 2006-08-18 2008-02-21 Ablynx N.V. Amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of deseases and disorders associated with il-6-mediated signalling
ME02345B (me) * 2007-07-17 2016-08-31 Squibb & Sons Llc MONOKLONSKA ANTlTELA PROTIV GLIPIKANA-3
CA2785414C (en) * 2009-12-25 2019-01-22 Tomoyuki Igawa Polypeptide modification method for purifying polypeptide multimers
EP2723771B1 (en) 2011-06-23 2019-09-11 Ablynx NV Serum albumin binding proteins
SG10201805064SA (en) 2011-06-23 2018-07-30 Ablynx Nv Techniques for predicting, detecting and reducing aspecific protein interference in assays involving immunoglobulin single variable domains
EP4707303A2 (en) 2014-05-16 2026-03-11 Ablynx NV Improved immunoglobulin variable domains
MA40764A (fr) * 2014-09-26 2017-08-01 Chugai Pharmaceutical Co Ltd Agent thérapeutique induisant une cytotoxicité
LT3611192T (lt) 2015-05-13 2025-06-25 Ablynx N.V. T ląstelių rekrutingo polipeptidai tcr alfa/beta reaktyvumo pagrindu
LT3374392T (lt) 2015-11-13 2022-01-25 Ablynx Nv Patobulinti serumo albuminą surišantys imunoglobulino kintami domenai
AU2016357460B2 (en) 2015-11-18 2023-07-27 Ablynx Nv Improved serum albumin binders
US11072666B2 (en) 2016-03-14 2021-07-27 Chugai Seiyaku Kabushiki Kaisha Cell injury inducing therapeutic drug for use in cancer therapy
BR112019010061A2 (pt) 2016-11-16 2019-08-13 Ablynx Nv polipeptídeos de recrutamento de células t capazes de se ligarem ao cd123 e tcr alfa/beta
RU2022101604A (ru) 2016-12-07 2022-03-29 Аблинкс Нв Улучшенные отдельные вариабельные домены иммуноглобулина, связывающиеся с сывороточным альбумином
IL267897B2 (en) 2017-01-17 2025-02-01 Ablynx Nv Improved serum albumin binders
JP7219220B2 (ja) 2017-01-17 2023-02-07 アブリンクス エン.ヴェー. 改善された血清アルブミン結合剤

Similar Documents

Publication Publication Date Title
JP2023553697A5 (https=)
JP2023504914A5 (https=)
JP2024063213A5 (https=)
JP2020195399A5 (https=)
JP2020186248A5 (https=)
JP2020500510A5 (https=)
JP2023518596A5 (https=)
JP2012520059A5 (https=)
JP2018171063A5 (https=)
JP2023553694A5 (https=)
CN102906112A (zh) Trail r2-特异性多聚体支架
JP2021508449A5 (https=)
JP2018537421A5 (https=)
JP2023528207A5 (https=)
JP2017519503A5 (https=)
CN108473563A (zh) 改进的tnf结合剂
JP2024504923A5 (https=)
JP2025504625A5 (https=)
JP2025504909A5 (https=)
JP2024547218A5 (https=)
JP2005522192A5 (https=)
JP2023544211A5 (https=)
JP2025530888A5 (https=)
CN117069844B (zh) 包含特定等电点的抗人bcma纳米抗体的双特异性抗体及应用
JP2022530742A5 (https=)