JP2020186248A5 - - Google Patents
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- JP2020186248A5 JP2020186248A5 JP2020128994A JP2020128994A JP2020186248A5 JP 2020186248 A5 JP2020186248 A5 JP 2020186248A5 JP 2020128994 A JP2020128994 A JP 2020128994A JP 2020128994 A JP2020128994 A JP 2020128994A JP 2020186248 A5 JP2020186248 A5 JP 2020186248A5
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- Prior art keywords
- antibody
- seq
- polypeptide
- bispecific antibody
- amino acid
- Prior art date
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2021150755A JP7241827B2 (ja) | 2015-01-02 | 2021-09-16 | 血漿カリクレインおよび第xii因子に対する二重特異性抗体 |
| JP2023035060A JP7635285B2 (ja) | 2015-01-02 | 2023-03-07 | 血漿カリクレインおよび第xii因子に対する二重特異性抗体 |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562099236P | 2015-01-02 | 2015-01-02 | |
| US62/099,236 | 2015-01-02 | ||
| US201562200363P | 2015-08-03 | 2015-08-03 | |
| US62/200,363 | 2015-08-03 | ||
| US201562261609P | 2015-12-01 | 2015-12-01 | |
| US62/261,609 | 2015-12-01 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017534345A Division JP6744313B2 (ja) | 2015-01-02 | 2015-12-31 | 血漿カリクレインおよび第xii因子に対する二重特異性抗体 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021150755A Division JP7241827B2 (ja) | 2015-01-02 | 2021-09-16 | 血漿カリクレインおよび第xii因子に対する二重特異性抗体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020186248A JP2020186248A (ja) | 2020-11-19 |
| JP2020186248A5 true JP2020186248A5 (https=) | 2021-04-30 |
| JP7003347B2 JP7003347B2 (ja) | 2022-02-04 |
Family
ID=56285069
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017534345A Active JP6744313B2 (ja) | 2015-01-02 | 2015-12-31 | 血漿カリクレインおよび第xii因子に対する二重特異性抗体 |
| JP2020128994A Active JP7003347B2 (ja) | 2015-01-02 | 2020-07-30 | 血漿カリクレインおよび第xii因子に対する二重特異性抗体 |
| JP2021150755A Active JP7241827B2 (ja) | 2015-01-02 | 2021-09-16 | 血漿カリクレインおよび第xii因子に対する二重特異性抗体 |
| JP2023035060A Active JP7635285B2 (ja) | 2015-01-02 | 2023-03-07 | 血漿カリクレインおよび第xii因子に対する二重特異性抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017534345A Active JP6744313B2 (ja) | 2015-01-02 | 2015-12-31 | 血漿カリクレインおよび第xii因子に対する二重特異性抗体 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021150755A Active JP7241827B2 (ja) | 2015-01-02 | 2021-09-16 | 血漿カリクレインおよび第xii因子に対する二重特異性抗体 |
| JP2023035060A Active JP7635285B2 (ja) | 2015-01-02 | 2023-03-07 | 血漿カリクレインおよび第xii因子に対する二重特異性抗体 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US11390687B2 (https=) |
| EP (2) | EP3240570B1 (https=) |
| JP (4) | JP6744313B2 (https=) |
| KR (1) | KR102670705B1 (https=) |
| CN (2) | CN107405399B (https=) |
| AU (2) | AU2015373910B2 (https=) |
| CA (1) | CA2972800A1 (https=) |
| CO (1) | CO2017007123A2 (https=) |
| EA (1) | EA201791527A1 (https=) |
| IL (2) | IL253180B2 (https=) |
| MX (2) | MX2017008541A (https=) |
| NZ (1) | NZ771568A (https=) |
| WO (1) | WO2016109774A1 (https=) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107405399B (zh) | 2015-01-02 | 2022-02-08 | 武田药品工业株式会社 | 针对血浆激肽释放酶和因子xii的双特异性抗体 |
| AU2016297018B9 (en) * | 2015-07-21 | 2022-12-01 | Takeda Pharmaceutical Company Limited | A monoclonal antibody inhibitor of factor XIIa |
| EA201990730A1 (ru) * | 2016-09-16 | 2019-08-30 | Дайэкс Корп. | Рнк-биомаркеры для наследственного ангионевротического отека |
| AU2018219887B2 (en) | 2017-02-08 | 2024-08-15 | Dragonfly Therapeutics, LLC | Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer |
| CN110944661A (zh) | 2017-02-20 | 2020-03-31 | 蜻蜓疗法股份有限公司 | 结合her2、nkg2d和cd16的蛋白质 |
| EP3668893A4 (en) * | 2017-08-16 | 2021-08-04 | Dragonfly Therapeutics, Inc. | PROTEINS BINDING TO NKG2D, CD16 AND EGFR, HLA-E, CCR4, OR PD-L1 |
| MX2020003888A (es) * | 2017-10-18 | 2020-11-06 | Regenxbio Inc | Anticuerpos terapeuticos postraduccionalmente modificados completamente humanos. |
| CN119291194A (zh) * | 2018-01-12 | 2025-01-10 | 建新公司 | 用于定量多肽的方法 |
| CA3237846A1 (en) | 2018-02-08 | 2019-08-15 | Dragonfly Therapeutics, Inc. | Antibody variable domains targeting the nkg2d receptor |
| BR112020015994A2 (pt) | 2018-02-08 | 2020-12-15 | Dragonfly Therapeutics, Inc. | Terapia de combinação do câncer que envolve proteínas de ligação multiespecíficas que ativam células natural killer |
| WO2019164930A1 (en) | 2018-02-20 | 2019-08-29 | Dragonfly Therapeutics, Inc. | Multi-specific binding proteins that bind cd33, nkg2d, and cd16, and methods of use |
| JP7412001B2 (ja) * | 2018-06-08 | 2024-01-12 | 株式会社モダリス | 改変されたCas9タンパク質及びその用途 |
| JP2021530989A (ja) * | 2018-07-11 | 2021-11-18 | モメンタ ファーマシューティカルズ インコーポレイテッド | PD−L1を標的とした改変されたFc抗原結合ドメイン構築体に関する組成物および方法 |
| EA202091888A1 (ru) | 2018-08-08 | 2020-10-23 | Драгонфлай Терапьютикс, Инк. | Вариабельные домены антител, нацеленные на рецептор nkg2d |
| KR102835308B1 (ko) | 2018-08-08 | 2025-07-21 | 드래곤플라이 쎄라퓨틱스, 인크. | Nkg2d, cd16 및 종양 관련 항원에 결합하는 단백질 |
| JP2021534096A (ja) * | 2018-08-08 | 2021-12-09 | ドラゴンフライ セラピューティクス, インコーポレイテッド | Nkg2d、cd16および腫瘍関連抗原に結合するタンパク質 |
| EP3833392A4 (en) | 2018-08-08 | 2022-05-18 | Dragonfly Therapeutics, Inc. | MULTISPECIFIC BINDING PROTEINS FOR BINDING CD33, NKG2D AND CD16 AND METHODS OF USE |
| JP2022512688A (ja) * | 2018-10-24 | 2022-02-07 | シャイア-エヌピーエス ファーマシューティカルズ インコーポレイテッド | Glp-2融合ポリペプチドならびに消化管の状態の処置および予防のための使用 |
| BR112022001368A2 (pt) | 2019-07-26 | 2022-05-24 | Janssen Biotech Inc | Proteínas que compreendem domínios de ligação ao antígeno de peptidase 2 relacionada à calicreína e seus usos |
| JP7512394B2 (ja) | 2020-05-06 | 2024-07-08 | ドラゴンフライ セラピューティクス, インコーポレイテッド | Nkg2d、cd16及びclec12aに結合するタンパク質 |
| US20230390418A1 (en) * | 2020-10-29 | 2023-12-07 | Regenxbio Inc. | Vectorized factor xii antibodies and administration thereof |
| CN114790245A (zh) * | 2021-01-25 | 2022-07-26 | 成都康弘生物科技有限公司 | 一种抗体及其用途 |
| CN114790246A (zh) * | 2021-01-25 | 2022-07-26 | 成都康弘生物科技有限公司 | 一种抗体及其用途 |
| EP4301774A4 (en) | 2021-03-03 | 2025-08-13 | Dragonfly Therapeutics Inc | METHODS OF TREATING CANCER USING MULTI-SPECIFIC BINDING PROTEINS THAT BIND TO NKG2D, CD16, AND A TUMOR-ASSOCIATED ANTIGEN |
| MX2023012489A (es) * | 2021-04-22 | 2023-11-22 | Guangdong Fapon Biopharma Inc | Polipeptido de fusion biespecifico multifuncional. |
| WO2024238407A2 (en) * | 2023-05-12 | 2024-11-21 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods of treating dilated cardiomyopathy and heart failure |
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| KR102320178B1 (ko) * | 2011-01-06 | 2021-11-02 | 다케다 파머수티컬 컴패니 리미티드 | 혈장 칼리크레인 결합 단백질 |
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| US9574013B2 (en) | 2012-12-07 | 2017-02-21 | Vanderbilt University | Antibodies against factor XII and uses thereof |
| US10690670B2 (en) | 2013-01-20 | 2020-06-23 | Dyax Corp. | Assays for determining levels of plasma protease C1 inhibitor |
| AU2014240045A1 (en) * | 2013-03-15 | 2015-09-10 | Dyax Corp. | Anti-plasma kallikrein antibodies |
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| CN105722859B (zh) | 2013-07-25 | 2021-05-07 | 西托姆克斯治疗公司 | 多特异性抗体、多特异性可活化抗体及其使用方法 |
| CN107405399B (zh) | 2015-01-02 | 2022-02-08 | 武田药品工业株式会社 | 针对血浆激肽释放酶和因子xii的双特异性抗体 |
| AU2016297018B9 (en) * | 2015-07-21 | 2022-12-01 | Takeda Pharmaceutical Company Limited | A monoclonal antibody inhibitor of factor XIIa |
| EP3263803B1 (en) | 2016-06-30 | 2019-08-14 | ABB Schweiz AG | Substation |
-
2015
- 2015-12-31 CN CN201580075633.1A patent/CN107405399B/zh active Active
- 2015-12-31 JP JP2017534345A patent/JP6744313B2/ja active Active
- 2015-12-31 KR KR1020177021610A patent/KR102670705B1/ko active Active
- 2015-12-31 IL IL253180A patent/IL253180B2/en unknown
- 2015-12-31 EA EA201791527A patent/EA201791527A1/ru unknown
- 2015-12-31 MX MX2017008541A patent/MX2017008541A/es unknown
- 2015-12-31 NZ NZ771568A patent/NZ771568A/en unknown
- 2015-12-31 CN CN202210054884.3A patent/CN114316061B/zh active Active
- 2015-12-31 IL IL298086A patent/IL298086B2/en unknown
- 2015-12-31 EP EP15876336.7A patent/EP3240570B1/en active Active
- 2015-12-31 US US15/541,066 patent/US11390687B2/en active Active
- 2015-12-31 AU AU2015373910A patent/AU2015373910B2/en active Active
- 2015-12-31 CA CA2972800A patent/CA2972800A1/en active Pending
- 2015-12-31 EP EP25204079.5A patent/EP4670785A3/en active Pending
- 2015-12-31 WO PCT/US2015/068238 patent/WO2016109774A1/en not_active Ceased
-
2017
- 2017-06-26 MX MX2024000317A patent/MX2024000317A/es unknown
- 2017-07-17 CO CONC2017/0007123A patent/CO2017007123A2/es unknown
-
2020
- 2020-07-30 JP JP2020128994A patent/JP7003347B2/ja active Active
-
2021
- 2021-09-16 JP JP2021150755A patent/JP7241827B2/ja active Active
-
2022
- 2022-02-17 AU AU2022201076A patent/AU2022201076B2/en active Active
- 2022-06-13 US US17/838,769 patent/US12240918B2/en active Active
-
2023
- 2023-03-07 JP JP2023035060A patent/JP7635285B2/ja active Active
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