JP2025504909A5 - - Google Patents

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Publication number
JP2025504909A5
JP2025504909A5 JP2024544393A JP2024544393A JP2025504909A5 JP 2025504909 A5 JP2025504909 A5 JP 2025504909A5 JP 2024544393 A JP2024544393 A JP 2024544393A JP 2024544393 A JP2024544393 A JP 2024544393A JP 2025504909 A5 JP2025504909 A5 JP 2025504909A5
Authority
JP
Japan
Prior art keywords
binding domain
binding
seq
fusion protein
triple
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2024544393A
Other languages
English (en)
Japanese (ja)
Other versions
JP2025504909A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CA2023/050103 external-priority patent/WO2023141713A1/en
Publication of JP2025504909A publication Critical patent/JP2025504909A/ja
Publication of JP2025504909A5 publication Critical patent/JP2025504909A5/ja
Pending legal-status Critical Current

Links

JP2024544393A 2022-01-26 2023-01-26 免疫調節性三重特異性t細胞エンゲージャー融合タンパク質 Pending JP2025504909A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202263303481P 2022-01-26 2022-01-26
US63/303,481 2022-01-26
US202263417655P 2022-10-19 2022-10-19
US63/417,655 2022-10-19
PCT/CA2023/050103 WO2023141713A1 (en) 2022-01-26 2023-01-26 Immunomodulatory trispecific t cell engager fusion proteins

Publications (2)

Publication Number Publication Date
JP2025504909A JP2025504909A (ja) 2025-02-19
JP2025504909A5 true JP2025504909A5 (https=) 2026-01-29

Family

ID=87469895

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2024544393A Pending JP2025504909A (ja) 2022-01-26 2023-01-26 免疫調節性三重特異性t細胞エンゲージャー融合タンパク質

Country Status (9)

Country Link
US (1) US20250019440A1 (https=)
EP (1) EP4469488A4 (https=)
JP (1) JP2025504909A (https=)
KR (1) KR20240137058A (https=)
AU (1) AU2023212483A1 (https=)
CA (1) CA3247443A1 (https=)
IL (1) IL314169A (https=)
MX (1) MX2024009165A (https=)
WO (1) WO2023141713A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2023312397A1 (en) * 2022-07-29 2025-03-13 Zymeworks Bc Inc. Multivalent and bispecific antibody constructs and methods of use thereof
CA3266966A1 (en) * 2022-10-19 2024-04-25 Zymeworks Bc Inc. TRIVALENT AND TRISPECIFIC ANTIBODY CONSTRUCTIONS AND THEIR METHODS OF USE
WO2025085862A2 (en) * 2023-10-20 2025-04-24 BioNTech SE Multispecific t cell engagers compositions and methods of use thereof
WO2025122988A2 (en) * 2023-12-08 2025-06-12 Aarvik Therapeutics, Inc. Engineered antibodies and immunoconjugates and methods of use
TW202600597A (zh) * 2024-03-04 2026-01-01 加拿大商酵活英屬哥倫比亞有限公司 靶向dll3之三特異性抗體構築體及其使用方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3827019A1 (en) * 2018-07-24 2021-06-02 Inhibrx, Inc. Multispecific polypeptide constructs containing a constrained cd3 binding domain and a receptor binding region and methods of using the same
EP3816185A1 (en) * 2019-11-04 2021-05-05 Numab Therapeutics AG Multispecific antibody directed against pd-l1 and a tumor-associated antigen
TWI908779B (zh) * 2020-03-17 2025-12-21 美商西雅圖免疫公司 引導及導航控制(gnc)抗體樣蛋白質及製造與使用其之方法
WO2022016270A1 (en) * 2020-07-20 2022-01-27 Zymeworks Inc. Fusion proteins comprising a ligand-receptor pair and a biologically functional protein

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