JP2023552528A5 - - Google Patents

Info

Publication number
JP2023552528A5
JP2023552528A5 JP2023532459A JP2023532459A JP2023552528A5 JP 2023552528 A5 JP2023552528 A5 JP 2023552528A5 JP 2023532459 A JP2023532459 A JP 2023532459A JP 2023532459 A JP2023532459 A JP 2023532459A JP 2023552528 A5 JP2023552528 A5 JP 2023552528A5
Authority
JP
Japan
Prior art keywords
seq
nucleic acid
acid sequence
cyp
enzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023532459A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023552528A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2021/061025 external-priority patent/WO2022115710A1/en
Publication of JP2023552528A publication Critical patent/JP2023552528A/ja
Publication of JP2023552528A5 publication Critical patent/JP2023552528A5/ja
Pending legal-status Critical Current

Links

JP2023532459A 2020-11-30 2021-11-29 Lcaおよび3-kcaをudcaおよび3-kudcaに変換するための酵素的方法 Pending JP2023552528A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063119188P 2020-11-30 2020-11-30
US63/119,188 2020-11-30
PCT/US2021/061025 WO2022115710A1 (en) 2020-11-30 2021-11-29 Enzymatic methods for converting lca and 3-kca to udca and 3-kudca

Publications (2)

Publication Number Publication Date
JP2023552528A JP2023552528A (ja) 2023-12-18
JP2023552528A5 true JP2023552528A5 (https=) 2024-12-06

Family

ID=81754944

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023532459A Pending JP2023552528A (ja) 2020-11-30 2021-11-29 Lcaおよび3-kcaをudcaおよび3-kudcaに変換するための酵素的方法

Country Status (8)

Country Link
US (1) US20230416800A1 (https=)
EP (1) EP4251169A4 (https=)
JP (1) JP2023552528A (https=)
KR (1) KR20230116864A (https=)
CN (1) CN116670147A (https=)
AU (1) AU2021385425A1 (https=)
CA (1) CA3201311A1 (https=)
WO (1) WO2022115710A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4665352A2 (en) * 2023-02-14 2025-12-24 Epimeron USA, Inc. Recombinant polypeptides for biosynthesis of ursodeoxycholic acid (udca)
CN117025709A (zh) * 2023-07-31 2023-11-10 华南理工大学 一种细胞色素p450酶联合细胞色素p450还原酶在合成熊去氧胆酸中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58155098A (ja) * 1982-03-09 1983-09-14 Yakult Honsha Co Ltd 微生物によるウルソデオキシコ−ル酸の製造法
US5989855A (en) * 1996-03-29 1999-11-23 Tokyo Tanabe Company Limited Bile acid converting microorganism and process for preparing bile acid
WO2013086499A2 (en) * 2011-12-09 2013-06-13 Ceres, Inc. Transgenic plants having altered biomass composition
EP3444340B1 (de) * 2014-07-29 2020-04-15 Pharmazell GmbH 7beta-hydroxysteroid dehydrogenase-mutanten und verfahren zur herstellung von ursodesoxycholsäure
IT201900017411A1 (it) * 2019-09-27 2021-03-27 Ice S P A Processo di preparazione di acido ursodesossicolico

Similar Documents

Publication Publication Date Title
JP2023552528A5 (https=)
JP6469874B2 (ja) 新規プロモーター及びその用途
CN1032315C (zh) 在酵母中生产乙型肝炎病毒蛋白质的方法
JP5357011B2 (ja) 遺伝的に操作された微生物株を用いる、スフィンゴイド塩基の改善された生産
JP4963488B2 (ja) 変異体酵母及びこれを用いた物質生産方法
JP2025024050A5 (https=)
JP2006504412A5 (https=)
EP2669375A1 (en) Yeast for transformation and process for producing protein
JP2021514621A (ja) マイコスポリン様アミノ酸を生産する微生物及びそれを用いたマイコスポリン様アミノ酸の生産方法
Kang et al. Hansenula polymorpha
US5656729A (en) Method for highly purifying human serum albumin
CN111893126A (zh) 碱性蛋白酶基因、碱性蛋白酶及其制备方法和应用
Kunze et al. Hansenula polymorpha (Pichia angusta): biology and applications
JP2009027999A (ja) シス−アコニット酸デカルボキシラーゼをコードするdna、シス−アコニット酸デカルボキシラーゼの製造方法、及び、イタコン酸の製造方法
JP2011507507A (ja) マルチマー性前駆体のinvivoタンパク質分解的プロセシングによる関心対象のタンパク質の分泌収量の改善
CN110582573A (zh) 植酸酶在黑曲霉中表达
JPH06509229A (ja) シクロヘキシミド耐性タンパク質及びヌクレオチド配列
JP5881034B2 (ja) 糸状菌変異株及びこれを用いたタンパク質の製造方法
JP2905230B2 (ja) ヒトリゾチームを産生する方法
CN110791508A (zh) 密码子优化的片球菌素基因、表达载体及重组工程菌株
JPWO2016056610A1 (ja) 7デヒドロコレステロール及びビタミンd3の製造法
CN107384979B (zh) 高渗透压甘油蛋白激酶基因RKHog1的用途
JP5846417B2 (ja) 形質転換体の培養方法及びイタコン酸の製造方法
Guengerich et al. A platform for heterologous gene expression based on the methylotrophic yeast Hansenula polymorpha
Hisamori et al. Cloning and expression analysis of a cDNA encoding an oxaloacetate acetylhydrolase from the brown-rot fungus Fomitopsis palustris