|
US5139A
(en)
|
|
1847-06-05 |
|
Cajsfkles |
|
US5173A
(en)
|
|
1847-06-26 |
|
Machinery for |
|
US414A
(en)
|
|
1837-09-28 |
|
Moetise-latch foe |
|
US941A
(en)
|
|
1838-09-22 |
|
Machine for sawing shingles and staves |
|
JPS5927900A
(ja)
|
1982-08-09 |
1984-02-14 |
Wakunaga Seiyaku Kk |
固定化オリゴヌクレオチド
|
|
FR2540122B1
(fr)
|
1983-01-27 |
1985-11-29 |
Centre Nat Rech Scient |
Nouveaux composes comportant une sequence d'oligonucleotide liee a un agent d'intercalation, leur procede de synthese et leur application
|
|
US4605735A
(en)
|
1983-02-14 |
1986-08-12 |
Wakunaga Seiyaku Kabushiki Kaisha |
Oligonucleotide derivatives
|
|
US4948882A
(en)
|
1983-02-22 |
1990-08-14 |
Syngene, Inc. |
Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis
|
|
US4824941A
(en)
|
1983-03-10 |
1989-04-25 |
Julian Gordon |
Specific antibody to the native form of 2'5'-oligonucleotides, the method of preparation and the use as reagents in immunoassays or for binding 2'5'-oligonucleotides in biological systems
|
|
US4587044A
(en)
|
1983-09-01 |
1986-05-06 |
The Johns Hopkins University |
Linkage of proteins to nucleic acids
|
|
US5118802A
(en)
|
1983-12-20 |
1992-06-02 |
California Institute Of Technology |
DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside
|
|
US5258506A
(en)
|
1984-10-16 |
1993-11-02 |
Chiron Corporation |
Photolabile reagents for incorporation into oligonucleotide chains
|
|
US5430136A
(en)
|
1984-10-16 |
1995-07-04 |
Chiron Corporation |
Oligonucleotides having selectably cleavable and/or abasic sites
|
|
US4828979A
(en)
|
1984-11-08 |
1989-05-09 |
Life Technologies, Inc. |
Nucleotide analogs for nucleic acid labeling and detection
|
|
US4897355A
(en)
|
1985-01-07 |
1990-01-30 |
Syntex (U.S.A.) Inc. |
N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
|
|
US4683202A
(en)
|
1985-03-28 |
1987-07-28 |
Cetus Corporation |
Process for amplifying nucleic acid sequences
|
|
US4762779A
(en)
|
1985-06-13 |
1988-08-09 |
Amgen Inc. |
Compositions and methods for functionalizing nucleic acids
|
|
US5139941A
(en)
|
1985-10-31 |
1992-08-18 |
University Of Florida Research Foundation, Inc. |
AAV transduction vectors
|
|
US5317098A
(en)
|
1986-03-17 |
1994-05-31 |
Hiroaki Shizuya |
Non-radioisotope tagging of fragments
|
|
JPS638396A
(ja)
|
1986-06-30 |
1988-01-14 |
Wakunaga Pharmaceut Co Ltd |
ポリ標識化オリゴヌクレオチド誘導体
|
|
US4837028A
(en)
|
1986-12-24 |
1989-06-06 |
Liposome Technology, Inc. |
Liposomes with enhanced circulation time
|
|
US4920016A
(en)
|
1986-12-24 |
1990-04-24 |
Linear Technology, Inc. |
Liposomes with enhanced circulation time
|
|
US4904582A
(en)
|
1987-06-11 |
1990-02-27 |
Synthetic Genetics |
Novel amphiphilic nucleic acid conjugates
|
|
US5585481A
(en)
|
1987-09-21 |
1996-12-17 |
Gen-Probe Incorporated |
Linking reagents for nucleotide probes
|
|
US5525465A
(en)
|
1987-10-28 |
1996-06-11 |
Howard Florey Institute Of Experimental Physiology And Medicine |
Oligonucleotide-polyamide conjugates and methods of production and applications of the same
|
|
DE3738460A1
(de)
|
1987-11-12 |
1989-05-24 |
Max Planck Gesellschaft |
Modifizierte oligonukleotide
|
|
US5082830A
(en)
|
1988-02-26 |
1992-01-21 |
Enzo Biochem, Inc. |
End labeled nucleotide probe
|
|
US5109124A
(en)
|
1988-06-01 |
1992-04-28 |
Biogen, Inc. |
Nucleic acid probe linked to a label having a terminal cysteine
|
|
US5262536A
(en)
|
1988-09-15 |
1993-11-16 |
E. I. Du Pont De Nemours And Company |
Reagents for the preparation of 5'-tagged oligonucleotides
|
|
US5512439A
(en)
|
1988-11-21 |
1996-04-30 |
Dynal As |
Oligonucleotide-linked magnetic particles and uses thereof
|
|
US5457183A
(en)
|
1989-03-06 |
1995-10-10 |
Board Of Regents, The University Of Texas System |
Hydroxylated texaphyrins
|
|
US5599923A
(en)
|
1989-03-06 |
1997-02-04 |
Board Of Regents, University Of Tx |
Texaphyrin metal complexes having improved functionalization
|
|
FR2645866B1
(fr)
|
1989-04-17 |
1991-07-05 |
Centre Nat Rech Scient |
Nouvelles lipopolyamines, leur preparation et leur emploi
|
|
US5391723A
(en)
|
1989-05-31 |
1995-02-21 |
Neorx Corporation |
Oligonucleotide conjugates
|
|
US4958013A
(en)
|
1989-06-06 |
1990-09-18 |
Northwestern University |
Cholesteryl modified oligonucleotides
|
|
US5744101A
(en)
|
1989-06-07 |
1998-04-28 |
Affymax Technologies N.V. |
Photolabile nucleoside protecting groups
|
|
US5143854A
(en)
|
1989-06-07 |
1992-09-01 |
Affymax Technologies N.V. |
Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
|
|
US5451463A
(en)
|
1989-08-28 |
1995-09-19 |
Clontech Laboratories, Inc. |
Non-nucleoside 1,3-diol reagents for labeling synthetic oligonucleotides
|
|
US5254469A
(en)
|
1989-09-12 |
1993-10-19 |
Eastman Kodak Company |
Oligonucleotide-enzyme conjugate that can be used as a probe in hybridization assays and polymerase chain reaction procedures
|
|
US5292873A
(en)
|
1989-11-29 |
1994-03-08 |
The Research Foundation Of State University Of New York |
Nucleic acids labeled with naphthoquinone probe
|
|
US5486603A
(en)
|
1990-01-08 |
1996-01-23 |
Gilead Sciences, Inc. |
Oligonucleotide having enhanced binding affinity
|
|
US5578718A
(en)
|
1990-01-11 |
1996-11-26 |
Isis Pharmaceuticals, Inc. |
Thiol-derivatized nucleosides
|
|
US7037646B1
(en)
|
1990-01-11 |
2006-05-02 |
Isis Pharmaceuticals, Inc. |
Amine-derivatized nucleosides and oligonucleosides
|
|
US6783931B1
(en)
|
1990-01-11 |
2004-08-31 |
Isis Pharmaceuticals, Inc. |
Amine-derivatized nucleosides and oligonucleosides
|
|
US5214136A
(en)
|
1990-02-20 |
1993-05-25 |
Gilead Sciences, Inc. |
Anthraquinone-derivatives oligonucleotides
|
|
AU7579991A
(en)
|
1990-02-20 |
1991-09-18 |
Gilead Sciences, Inc. |
Pseudonucleosides and pseudonucleotides and their polymers
|
|
US5264618A
(en)
|
1990-04-19 |
1993-11-23 |
Vical, Inc. |
Cationic lipids for intracellular delivery of biologically active molecules
|
|
ES2116977T3
(es)
|
1990-05-11 |
1998-08-01 |
Microprobe Corp |
Soportes solidos para ensayos de hibridacion de acidos nucleicos y metodos para inmovilizar oligonucleotidos de modo covalente.
|
|
AU8200191A
(en)
|
1990-07-09 |
1992-02-04 |
United States of America, as represented by the Secretary, U.S. Department of Commerce, The |
High efficiency packaging of mutant adeno-associated virus using amber suppressions
|
|
US5608046A
(en)
|
1990-07-27 |
1997-03-04 |
Isis Pharmaceuticals, Inc. |
Conjugated 4'-desmethyl nucleoside analog compounds
|
|
US5218105A
(en)
|
1990-07-27 |
1993-06-08 |
Isis Pharmaceuticals |
Polyamine conjugated oligonucleotides
|
|
US5688941A
(en)
|
1990-07-27 |
1997-11-18 |
Isis Pharmaceuticals, Inc. |
Methods of making conjugated 4' desmethyl nucleoside analog compounds
|
|
US5138045A
(en)
|
1990-07-27 |
1992-08-11 |
Isis Pharmaceuticals |
Polyamine conjugated oligonucleotides
|
|
US5245022A
(en)
|
1990-08-03 |
1993-09-14 |
Sterling Drug, Inc. |
Exonuclease resistant terminally substituted oligonucleotides
|
|
US5512667A
(en)
|
1990-08-28 |
1996-04-30 |
Reed; Michael W. |
Trifunctional intermediates for preparing 3'-tailed oligonucleotides
|
|
US5173414A
(en)
|
1990-10-30 |
1992-12-22 |
Applied Immune Sciences, Inc. |
Production of recombinant adeno-associated virus vectors
|
|
KR930702373A
(ko)
|
1990-11-08 |
1993-09-08 |
안토니 제이. 페이네 |
합성 올리고누클레오티드에 대한 다중 리포터(Reporter)그룹의 첨합
|
|
US5766855A
(en)
|
1991-05-24 |
1998-06-16 |
Buchardt, Deceased; Ole |
Peptide nucleic acids having enhanced binding affinity and sequence specificity
|
|
DK51092D0
(da)
|
1991-05-24 |
1992-04-15 |
Ole Buchardt |
Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
|
|
US5539082A
(en)
|
1993-04-26 |
1996-07-23 |
Nielsen; Peter E. |
Peptide nucleic acids
|
|
US5371241A
(en)
|
1991-07-19 |
1994-12-06 |
Pharmacia P-L Biochemicals Inc. |
Fluorescein labelled phosphoramidites
|
|
DE69233013T2
(de)
|
1991-08-20 |
2004-03-04 |
The Government Of The United States Of America As Represented By The Secretary Of National Institute Of Health, Office Of Technology Transfer |
Adenovirus vermittelter gentransfer in den gastrointestinaltrakt
|
|
US5283185A
(en)
|
1991-08-28 |
1994-02-01 |
University Of Tennessee Research Corporation |
Method for delivering nucleic acids into cells
|
|
CA2124087C
(en)
|
1991-11-22 |
2002-10-01 |
James L. Winkler |
Combinatorial strategies for polymer synthesis
|
|
US5565552A
(en)
|
1992-01-21 |
1996-10-15 |
Pharmacyclics, Inc. |
Method of expanded porphyrin-oligonucleotide conjugate synthesis
|
|
US5595726A
(en)
|
1992-01-21 |
1997-01-21 |
Pharmacyclics, Inc. |
Chromophore probe for detection of nucleic acid
|
|
EP0646178A1
(en)
|
1992-06-04 |
1995-04-05 |
The Regents Of The University Of California |
expression cassette with regularoty regions functional in the mammmlian host
|
|
AU4541093A
(en)
|
1992-06-18 |
1994-01-24 |
Genpharm International, Inc. |
Methods for producing transgenic non-human animals harboring a yeast artificial chromosome
|
|
US5272250A
(en)
|
1992-07-10 |
1993-12-21 |
Spielvogel Bernard F |
Boronated phosphoramidate compounds
|
|
DK0752248T3
(da)
|
1992-11-13 |
2000-11-13 |
Idec Pharma Corp |
Terapeutisk anvendelse af kimæriske og radioaktivt mærkede antistoffer mod humant B-lymfocytbegrænset differentieringsantig
|
|
US5869305A
(en)
|
1992-12-04 |
1999-02-09 |
The University Of Pittsburgh |
Recombinant viral vector system
|
|
US5574142A
(en)
|
1992-12-15 |
1996-11-12 |
Microprobe Corporation |
Peptide linkers for improved oligonucleotide delivery
|
|
US6294664B1
(en)
|
1993-07-29 |
2001-09-25 |
Isis Pharmaceuticals, Inc. |
Synthesis of oligonucleotides
|
|
US5539083A
(en)
|
1994-02-23 |
1996-07-23 |
Isis Pharmaceuticals, Inc. |
Peptide nucleic acid combinatorial libraries and improved methods of synthesis
|
|
US5543152A
(en)
|
1994-06-20 |
1996-08-06 |
Inex Pharmaceuticals Corporation |
Sphingosomes for enhanced drug delivery
|
|
US6204059B1
(en)
|
1994-06-30 |
2001-03-20 |
University Of Pittsburgh |
AAV capsid vehicles for molecular transfer
|
|
US5597696A
(en)
|
1994-07-18 |
1997-01-28 |
Becton Dickinson And Company |
Covalent cyanine dye oligonucleotide conjugates
|
|
US5580731A
(en)
|
1994-08-25 |
1996-12-03 |
Chiron Corporation |
N-4 modified pyrimidine deoxynucleotides and oligonucleotide probes synthesized therewith
|
|
US5556752A
(en)
|
1994-10-24 |
1996-09-17 |
Affymetrix, Inc. |
Surface-bound, unimolecular, double-stranded DNA
|
|
CA2220950A1
(en)
|
1995-05-26 |
1996-11-28 |
Somatix Therapy Corporation |
Delivery vehicles comprising stable lipid/nucleic acid complexes
|
|
US5981501A
(en)
|
1995-06-07 |
1999-11-09 |
Inex Pharmaceuticals Corp. |
Methods for encapsulating plasmids in lipid bilayers
|
|
US7422902B1
(en)
|
1995-06-07 |
2008-09-09 |
The University Of British Columbia |
Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer
|
|
US5976567A
(en)
|
1995-06-07 |
1999-11-02 |
Inex Pharmaceuticals Corp. |
Lipid-nucleic acid particles prepared via a hydrophobic lipid-nucleic acid complex intermediate and use for gene transfer
|
|
US5545531A
(en)
|
1995-06-07 |
1996-08-13 |
Affymax Technologies N.V. |
Methods for making a device for concurrently processing multiple biological chip assays
|
|
US6001650A
(en)
|
1995-08-03 |
1999-12-14 |
Avigen, Inc. |
High-efficiency wild-type-free AAV helper functions
|
|
US5801030A
(en)
|
1995-09-01 |
1998-09-01 |
Genvec, Inc. |
Methods and vectors for site-specific recombination
|
|
US6013516A
(en)
|
1995-10-06 |
2000-01-11 |
The Salk Institute For Biological Studies |
Vector and method of use for nucleic acid delivery to non-dividing cells
|
|
US5858397A
(en)
|
1995-10-11 |
1999-01-12 |
University Of British Columbia |
Liposomal formulations of mitoxantrone
|
|
US5854033A
(en)
|
1995-11-21 |
1998-12-29 |
Yale University |
Rolling circle replication reporter systems
|
|
ES2192672T3
(es)
|
1996-11-18 |
2003-10-16 |
Takeshi Imanishi |
Nuevos analogos de nucleotidos.
|
|
US6576752B1
(en)
|
1997-02-14 |
2003-06-10 |
Isis Pharmaceuticals, Inc. |
Aminooxy functionalized oligomers
|
|
US6034135A
(en)
|
1997-03-06 |
2000-03-07 |
Promega Biosciences, Inc. |
Dimeric cationic lipids
|
|
JP3756313B2
(ja)
|
1997-03-07 |
2006-03-15 |
武 今西 |
新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体
|
|
US6770748B2
(en)
|
1997-03-07 |
2004-08-03 |
Takeshi Imanishi |
Bicyclonucleoside and oligonucleotide analogue
|
|
JP4236812B2
(ja)
|
1997-09-12 |
2009-03-11 |
エクシコン エ／エス |
オリゴヌクレオチド類似体
|
|
US6136597A
(en)
|
1997-09-18 |
2000-10-24 |
The Salk Institute For Biological Studies |
RNA export element
|
|
US6639051B2
(en)
|
1997-10-20 |
2003-10-28 |
Curis, Inc. |
Regulation of epithelial tissue by hedgehog-like polypeptides, and formulations and uses related thereto
|
|
US5994136A
(en)
|
1997-12-12 |
1999-11-30 |
Cell Genesys, Inc. |
Method and means for producing high titer, safe, recombinant lentivirus vectors
|
|
US6320017B1
(en)
|
1997-12-23 |
2001-11-20 |
Inex Pharmaceuticals Corp. |
Polyamide oligomers
|
|
US6506559B1
(en)
|
1997-12-23 |
2003-01-14 |
Carnegie Institute Of Washington |
Genetic inhibition by double-stranded RNA
|
|
US6649881B2
(en)
|
1998-06-04 |
2003-11-18 |
American Water Heater Company |
Electric water heater with pulsed electronic control and detection
|
|
US6566131B1
(en)
|
2000-10-04 |
2003-05-20 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of Smad6 expression
|
|
AU747597B2
(en)
|
1998-07-20 |
2002-05-16 |
Inex Pharmaceuticals Corporation |
Liposomal encapsulated nucleic acid-complexes
|
|
US6410323B1
(en)
|
1999-08-31 |
2002-06-25 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of human Rho family gene expression
|
|
US6107091A
(en)
|
1998-12-03 |
2000-08-22 |
Isis Pharmaceuticals Inc. |
Antisense inhibition of G-alpha-16 expression
|
|
US5981732A
(en)
|
1998-12-04 |
1999-11-09 |
Isis Pharmaceuticals Inc. |
Antisense modulation of G-alpha-13 expression
|
|
ES2234563T5
(es)
|
1999-02-12 |
2018-01-17 |
Daiichi Sankyo Company, Limited |
Nuevos análogos de nucleósidos y oligonucleótidos
|
|
KR20020013513A
(ko)
|
1999-03-18 |
2002-02-20 |
추후제출 |
Ｘｙｌｏ-ｌｎａ 유사체
|
|
DE60029314T2
(de)
|
1999-03-24 |
2007-07-12 |
Exiqon A/S |
Verbesserte Synthese für -2.2.1. I Bicyclo-Nukleoside
|
|
US6046321A
(en)
|
1999-04-09 |
2000-04-04 |
Isis Pharmaceuticals Inc. |
Antisense modulation of G-alpha-i1 expression
|
|
US7053207B2
(en)
|
1999-05-04 |
2006-05-30 |
Exiqon A/S |
L-ribo-LNA analogues
|
|
CA2379166C
(en)
|
1999-08-09 |
2013-03-26 |
Targeted Genetics Corporation |
Enhancement of expression of a single-stranded, heterologous nucleotide sequence from recombinant viral vectors by designing the sequence such that it forms instrastrand base pairs
|
|
AU7406700A
(en)
|
1999-10-04 |
2001-05-10 |
Exiqon A/S |
Design of high affinity rnase h recruiting oligonucleotide
|
|
GB9927444D0
(en)
|
1999-11-19 |
2000-01-19 |
Cancer Res Campaign Tech |
Inhibiting gene expression
|
|
EP1272630A2
(en)
|
2000-03-16 |
2003-01-08 |
Genetica, Inc. |
Methods and compositions for rna interference
|
|
US6365354B1
(en)
|
2000-07-31 |
2002-04-02 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of lysophospholipase I expression
|
|
JP4413493B2
(ja)
|
2000-10-04 |
2010-02-10 |
サンタリス ファーマ アー／エス |
プリンｌｎａ類似体の改善された合成方法
|
|
US6566135B1
(en)
|
2000-10-04 |
2003-05-20 |
Isis Pharmaceuticals, Inc. |
Antisense modulation of caspase 6 expression
|
|
AU2002317437A1
(en)
|
2001-05-18 |
2002-12-03 |
Cureon A/S |
Therapeutic uses of lna-modified oligonucleotides in infectious diseases
|
|
ATE287413T1
(de)
|
2001-07-12 |
2005-02-15 |
Santaris Pharma As |
Verfahren zur herstellung des lna phosphoramidite
|
|
MX359371B
(es)
|
2001-11-13 |
2018-09-25 |
Univ Pennsylvania |
Un metodo para detectar y/o identificar secuencias del virus adeno-asociado y aislamiento de secuencias novedosas identificadas de ese modo.
|
|
PT1453547T
(pt)
|
2001-12-17 |
2016-12-28 |
Univ Pennsylvania |
Sequências do vírus adeno-associado (aav) do serotipo 8, vetores contendo as mesmas, e utilizações destas
|
|
JP4269260B2
(ja)
|
2003-06-05 |
2009-05-27 |
三浦工業株式会社 |
バルブ
|
|
EP2345731B1
(en)
|
2003-09-30 |
2015-10-21 |
The Trustees of the University of Pennsylvania |
Adeno-associated virus (AAV) clades, sequences, vectors containing same, and uses thereof
|
|
WO2005061710A1
(en)
|
2003-12-23 |
2005-07-07 |
Santaris Pharma A/S |
Oligomeric compounds for the modulation of bcl-2
|
|
US20060058255A1
(en)
|
2004-03-01 |
2006-03-16 |
Jianzhu Chen |
RNAi-based therapeutics for allergic rhinitis and asthma
|
|
WO2005116204A1
(ja)
*
|
2004-05-11 |
2005-12-08 |
Rnai Co., Ltd. |
Ｒｎａ干渉を生じさせるポリヌクレオチド、および、これを用いた遺伝子発現抑制方法
|
|
WO2005124343A2
(en)
*
|
2004-06-16 |
2005-12-29 |
Galapagos N.V. |
Methods for modulating bone tissue formation, orthogenic agents and pharmaceutical compositions
|
|
US7183969B2
(en)
|
2004-12-22 |
2007-02-27 |
Raytheon Company |
System and technique for calibrating radar arrays
|
|
ES2525067T3
(es)
|
2005-04-07 |
2014-12-17 |
The Trustees Of The University Of Pennsylvania |
Método de incremento de la función de un vector de AAV
|
|
JP4495210B2
(ja)
|
2005-06-09 |
2010-06-30 |
パナソニック株式会社 |
振幅誤差補償装置及び直交度誤差補償装置
|
|
WO2009073809A2
(en)
|
2007-12-04 |
2009-06-11 |
Alnylam Pharmaceuticals, Inc. |
Carbohydrate conjugates as delivery agents for oligonucleotides
|
|
JP2011512156A
(ja)
|
2008-02-19 |
2011-04-21 |
アムステルダム モレキュラー セラピューティクス ビー．ブイ． |
昆虫細胞におけるパルボウイルスｒｅｐ及びｃａｐタンパク質の発現の最適化
|
|
EP2425000B1
(en)
|
2009-04-30 |
2019-02-20 |
The Trustees Of The University Of Pennsylvania |
Compositions for targeting conducting airway cells comprising adeno-associated virus constructs
|
|
US8734809B2
(en)
|
2009-05-28 |
2014-05-27 |
University Of Massachusetts |
AAV's and uses thereof
|
|
KR101766408B1
(ko)
|
2009-06-10 |
2017-08-10 |
알닐람 파마슈티칼스 인코포레이티드 |
향상된 지질 조성물
|
|
US8927514B2
(en)
|
2010-04-30 |
2015-01-06 |
City Of Hope |
Recombinant adeno-associated vectors for targeted treatment
|
|
US8628966B2
(en)
|
2010-04-30 |
2014-01-14 |
City Of Hope |
CD34-derived recombinant adeno-associated vectors for stem cell transduction and systemic therapeutic gene transfer
|
|
WO2012057363A1
(ja)
|
2010-10-27 |
2012-05-03 |
学校法人自治医科大学 |
神経系細胞への遺伝子導入のためのアデノ随伴ウイルスビリオン
|
|
WO2012109570A1
(en)
|
2011-02-10 |
2012-08-16 |
The University Of North Carolina At Chapel Hill |
Viral vectors with modified transduction profiles and methods of making and using the same
|
|
CN105755044A
(zh)
|
2011-04-22 |
2016-07-13 |
加利福尼亚大学董事会 |
具有变异衣壳的腺相关病毒病毒体及其使用方法
|
|
US20140275211A1
(en)
|
2011-06-21 |
2014-09-18 |
Alnylam Pharmaceuticals, Inc. |
Assays and methods for determining activity of a therapeutic agent in a subject
|
|
ES2857773T5
(es)
|
2011-08-24 |
2024-06-04 |
Univ Leland Stanford Junior |
Nuevas proteínas de la cápside de AAV para la transferencia de ácidos nucleicos
|
|
WO2013170078A1
(en)
|
2012-05-09 |
2013-11-14 |
Oregon Health & Science University |
Adeno associated virus plasmids and vectors
|
|
CA2905952A1
(en)
|
2013-03-13 |
2014-10-02 |
The Children's Hospital Of Philadelphia |
Adeno-associated virus vectors and methods of use thereof
|
|
MX388221B
(es)
|
2013-04-20 |
2025-03-19 |
Res Institute At Nationwide Children´S Hospital |
ADMINISTRACIÓN DE VIRUS ADENO-ASOCIADO RECOMBINANTE DE CONSTRUCCIONES DE POLINUCLÉOTIDOS U7snRNA DIRIGIDA AL EXÓN 2.
|
|
DK2992098T3
(da)
|
2013-05-01 |
2019-06-17 |
Ionis Pharmaceuticals Inc |
Sammensætninger og fremgangsmåder til modulering af hbv- og ttr-ekspression
|
|
WO2014195755A1
(en)
|
2013-06-05 |
2014-12-11 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Hydrophobically modified antisense oligonucleotides comprising a ketal group
|
|
WO2014195754A1
(en)
|
2013-06-05 |
2014-12-11 |
Institut National De La Sante Et De La Recherche Medicale (Inserm) |
Hydrophobically modified antisense oligonucleotides comprising a triple alkyl chain
|
|
IL297919A
(en)
|
2013-07-22 |
2023-01-01 |
Childrens Hospital Philadelphia |
Variant aav and compositions, methods and uses for gene transfer to cells, organs and tissues
|
|
ES2739288T3
(es)
|
2013-09-13 |
2020-01-30 |
California Inst Of Techn |
Recuperación selectiva
|
|
US10016424B2
(en)
*
|
2013-09-16 |
2018-07-10 |
INSERM (Institut National de la Santé et de la Recherche Médicale |
Method and pharmaceutical composition for use in the treatment of epilepsy
|
|
CN106232618A
(zh)
|
2013-10-11 |
2016-12-14 |
马萨诸塞眼科耳科诊所 |
预测祖先病毒序列的方法及其用途
|
|
WO2015073360A2
(en)
|
2013-11-12 |
2015-05-21 |
New England Biolabs Inc. |
Dnmt inhibitors
|
|
WO2015164757A1
(en)
|
2014-04-25 |
2015-10-29 |
Oregon Health & Science University |
Methods of viral neutralizing antibody epitope mapping
|
|
EP3151866B1
(en)
|
2014-06-09 |
2023-03-08 |
Voyager Therapeutics, Inc. |
Chimeric capsids
|
|
AU2015320694B2
(en)
|
2014-09-24 |
2021-11-11 |
City Of Hope |
Adeno-associated virus vector variants for high efficiency genome editing and methods thereof
|
|
JP6627515B2
(ja)
|
2015-02-06 |
2020-01-08 |
Jnc株式会社 |
３，６−ジヒドロ−２ｈ−ピランを有する誘電率異方性が負の液晶性化合物、液晶組成物および液晶表示素子
|
|
US20180064748A1
(en)
*
|
2015-03-27 |
2018-03-08 |
Yeda Research And Development Co. Ltd. |
Methods of treating motor neuron diseases
|
|
JP6665466B2
(ja)
|
2015-09-26 |
2020-03-13 |
日亜化学工業株式会社 |
半導体発光素子及びその製造方法
|
|
WO2017070491A1
(en)
|
2015-10-23 |
2017-04-27 |
Applied Genetic Technologies Corporation |
Ophthalmic formulations
|
|
CA3059446A1
(en)
|
2017-04-18 |
2018-10-25 |
Alnylam Pharmaceuticals, Inc. |
Methods for the treatment of subjects having a hepatitis b virus (hbv) infection
|
|
EP3997225A1
(en)
*
|
2019-07-10 |
2022-05-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the treatment of epilepsy
|