JP2023532681A5 - - Google Patents
Info
- Publication number
- JP2023532681A5 JP2023532681A5 JP2022580239A JP2022580239A JP2023532681A5 JP 2023532681 A5 JP2023532681 A5 JP 2023532681A5 JP 2022580239 A JP2022580239 A JP 2022580239A JP 2022580239 A JP2022580239 A JP 2022580239A JP 2023532681 A5 JP2023532681 A5 JP 2023532681A5
- Authority
- JP
- Japan
- Prior art keywords
- xyl
- rha
- fuc
- saponin
- glc
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL2025904 | 2020-06-24 | ||
| NL2025904 | 2020-06-24 | ||
| PCT/EP2020/071045 WO2021014019A1 (en) | 2019-07-25 | 2020-07-24 | Saponin derivatives with improved therapeutic window |
| EPPCT/EP2020/071045 | 2020-07-24 | ||
| PCT/EP2021/067227 WO2021260054A2 (en) | 2020-06-24 | 2021-06-23 | Saponin derivatives with improved therapeutic window |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023532681A JP2023532681A (ja) | 2023-07-31 |
| JP2023532681A5 true JP2023532681A5 (https=) | 2024-06-27 |
Family
ID=79282018
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022580237A Pending JP2023532680A (ja) | 2020-06-24 | 2021-06-23 | 改善された治療濃度域を有するサポニン誘導体 |
| JP2022580239A Pending JP2023532681A (ja) | 2020-06-24 | 2021-06-23 | 改善された治療濃度域を有するサポニン誘導体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022580237A Pending JP2023532680A (ja) | 2020-06-24 | 2021-06-23 | 改善された治療濃度域を有するサポニン誘導体 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20230365617A1 (https=) |
| EP (2) | EP4171639A2 (https=) |
| JP (2) | JP2023532680A (https=) |
| KR (2) | KR20230043113A (https=) |
| CN (2) | CN116390932A (https=) |
| AU (2) | AU2021295868A1 (https=) |
| CA (2) | CA3184027A1 (https=) |
| IL (2) | IL299359A (https=) |
| MX (1) | MX2022016485A (https=) |
| WO (2) | WO2021260054A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20230043118A (ko) * | 2020-06-24 | 2023-03-30 | 사프렘 테크놀로지스 비.브이. | 사포닌 및 단일-도메인 항체의 접합체, 상기 접합체를 포함하는 약학적 조성물, 이의 치료 용도 |
| WO2024005485A1 (ko) * | 2022-06-26 | 2024-01-04 | 기초과학연구원 | 사포닌 유도체 화합물 및 이를 포함하는 코로나바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| KR102887798B1 (ko) * | 2022-06-26 | 2025-11-18 | 기초과학연구원 | 사포닌 유도체 화합물 및 이를 포함하는 코로나바이러스 감염증의 예방 또는 치료용 약학적 조성물 |
| CN119423084B (zh) * | 2024-11-07 | 2025-10-24 | 四川省烟草公司攀枝花市公司 | 川续断皂苷乙在蚜虫防治中的应用及杀蚜剂 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5583112A (en) | 1987-05-29 | 1996-12-10 | Cambridge Biotech Corporation | Saponin-antigen conjugates and the use thereof |
| US5273965A (en) * | 1992-07-02 | 1993-12-28 | Cambridge Biotech Corporation | Methods for enhancing drug delivery with modified saponins |
| US5650398A (en) * | 1992-07-02 | 1997-07-22 | Cambridge Biotech Corporation | Drug delivery enhancement via modified saponins |
| AU3724495A (en) * | 1994-09-13 | 1996-03-29 | Prizm Pharmaceuticals, Inc. | Conjugates of heparin-binding epidermal growth factor-like growth factor with targeted agents |
| JPH11505805A (ja) * | 1995-05-16 | 1999-05-25 | プリズム ファーマシューティカルズ，インコーポレイテッド | 治療的処置のための核酸およびリガンドを含有する組成物 |
| DE69828507T2 (de) * | 1997-05-20 | 2006-01-05 | Galenica Pharmaceuticals, Inc. | Triterpene-saponin analoga mit adjuvans und immunostimulierender wirkung |
| US6080725A (en) * | 1997-05-20 | 2000-06-27 | Galenica Pharmaceuticals, Inc. | Immunostimulating and vaccine compositions employing saponin analog adjuvants and uses thereof |
| WO2003037275A2 (en) * | 2001-10-31 | 2003-05-08 | Corixa Corporation | Compositions and methods for viral delivery |
| JP2005525344A (ja) * | 2002-02-04 | 2005-08-25 | コリクサ コーポレイション | アミノアルキルグルコサミニドホスフェートおよびサポニンを含む免疫刺激性組成物 |
| WO2004092329A2 (en) * | 2003-04-08 | 2004-10-28 | Galenica Pharmaceuticals, Inc. | Semi-synthetic saponin analogs with carrier and immune stimulatory activities for dna and rna vaccines |
| EP1623715B1 (en) * | 2004-07-13 | 2012-09-19 | Charité - Universitätsmedizin Berlin | A composition comprising a pharmacologically active agent coupled to a target cell specific component, and a saponin |
| WO2009143345A2 (en) * | 2008-05-22 | 2009-11-26 | University Of Massachusetts | Nucleic acid silencing agent-protein conjugates and use thereof for treating hcv-related disorders |
| CN105658230B (zh) * | 2013-08-29 | 2020-04-21 | 希望之城 | 细胞穿透缀合物及其使用方法 |
| KR102424785B1 (ko) | 2014-05-30 | 2022-07-25 | 메모리얼 슬로안 케터링 캔서 센터 | 최소 사포닌 유사체, 이의 합성법 및 용도 |
| EP3356371A4 (en) * | 2015-09-29 | 2020-06-24 | The University of Chicago | POLYMER CONJUGATE VACCINE |
| WO2017190020A1 (en) * | 2016-04-28 | 2017-11-02 | The Scripps Research Institute | Oligonucleotide conjugates and uses thereof |
| PE20210255A1 (es) * | 2016-12-01 | 2021-02-10 | Takeda Pharmaceuticals Co | Dinucleotido ciclico como agonistas de sting (estimulador de genes de interferon) |
| US11708388B2 (en) * | 2017-07-11 | 2023-07-25 | Freie Universität Berlin | Uses of a saponin and method for its isolation |
| SG11202106603UA (en) * | 2018-12-21 | 2021-07-29 | Sapreme Tech Bv | Biologically active cluster of molecules |
| EP4003425A2 (en) * | 2019-07-25 | 2022-06-01 | Sapreme Technologies B.V. | Bioactive saponin linked to a functional moiety |
-
2021
- 2021-06-23 WO PCT/EP2021/067227 patent/WO2021260054A2/en not_active Ceased
- 2021-06-23 CA CA3184027A patent/CA3184027A1/en active Pending
- 2021-06-23 JP JP2022580237A patent/JP2023532680A/ja active Pending
- 2021-06-23 WO PCT/EP2021/067239 patent/WO2021260061A2/en not_active Ceased
- 2021-06-23 KR KR1020237002633A patent/KR20230043113A/ko not_active Withdrawn
- 2021-06-23 IL IL299359A patent/IL299359A/en unknown
- 2021-06-23 CN CN202180051965.1A patent/CN116390932A/zh active Pending
- 2021-06-23 CN CN202180051953.9A patent/CN116615249A/zh active Pending
- 2021-06-23 MX MX2022016485A patent/MX2022016485A/es unknown
- 2021-06-23 IL IL299358A patent/IL299358A/en unknown
- 2021-06-23 EP EP21732938.2A patent/EP4171639A2/en active Pending
- 2021-06-23 US US18/012,698 patent/US20230365617A1/en active Pending
- 2021-06-23 CA CA3184041A patent/CA3184041A1/en active Pending
- 2021-06-23 AU AU2021295868A patent/AU2021295868A1/en active Pending
- 2021-06-23 US US18/012,694 patent/US20230277612A1/en active Pending
- 2021-06-23 EP EP21736583.2A patent/EP4171644A2/en active Pending
- 2021-06-23 KR KR1020237002612A patent/KR20230043112A/ko active Pending
- 2021-06-23 AU AU2021295292A patent/AU2021295292A1/en active Pending
- 2021-06-23 JP JP2022580239A patent/JP2023532681A/ja active Pending
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