JP2023533693A5 - - Google Patents
Info
- Publication number
- JP2023533693A5 JP2023533693A5 JP2022580238A JP2022580238A JP2023533693A5 JP 2023533693 A5 JP2023533693 A5 JP 2023533693A5 JP 2022580238 A JP2022580238 A JP 2022580238A JP 2022580238 A JP2022580238 A JP 2022580238A JP 2023533693 A5 JP2023533693 A5 JP 2023533693A5
- Authority
- JP
- Japan
- Prior art keywords
- xyl
- rha
- fuc
- glc
- saponin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL2025902 | 2020-06-24 | ||
| NL2025902 | 2020-06-24 | ||
| PCT/NL2021/050384 WO2021261992A1 (en) | 2020-06-24 | 2021-06-18 | Conjugate of galnac and saponin, therapeutic composition comprising said conjugate and a galnac-oligonucleotide conjugate |
| NLPCT/NL2021/050384 | 2021-06-18 | ||
| PCT/NL2021/050394 WO2021261998A1 (en) | 2020-06-24 | 2021-06-23 | Therapeutic combination of galnac-oligonucleotide conjugate and saponin, and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023533693A JP2023533693A (ja) | 2023-08-04 |
| JP2023533693A5 true JP2023533693A5 (https=) | 2024-07-01 |
Family
ID=76601666
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022580238A Pending JP2023533693A (ja) | 2020-06-24 | 2021-06-23 | ＧａｌＮＡｃ－オリゴヌクレオチドコンジュゲート及びサポニンの治療用配合物、及びその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20230293562A1 (https=) |
| EP (2) | EP4596052A3 (https=) |
| JP (1) | JP2023533693A (https=) |
| KR (1) | KR20230044196A (https=) |
| CN (1) | CN116194148A (https=) |
| AU (1) | AU2021296983A1 (https=) |
| CA (1) | CA3183881A1 (https=) |
| IL (1) | IL299349A (https=) |
| WO (1) | WO2021261998A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20260025101A (ko) * | 2023-06-02 | 2026-02-23 | 사프렘 테크놀로지스 비.브이. | 세포내 분자 표적을 통해 작용하는 치료적 이펙터 성분을 위한 개선된 치료 요법 |
| WO2025155911A1 (en) | 2024-01-18 | 2025-07-24 | Proqr Therapeutics Ii B.V. | Antisense oligonucleotides for the treatment of hurler syndrome |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011054811A1 (en) * | 2009-11-03 | 2011-05-12 | Santaris Pharma A/S | Rna antagonists targeting hsp27 combination therapy |
| MX2016005855A (es) * | 2013-11-14 | 2016-07-13 | Roche Innovation Ct Copenhagen As | Compuestos de conjugados antisentido de apolipoproteina b (apob). |
| SG11202106603UA (en) * | 2018-12-21 | 2021-07-29 | Sapreme Tech Bv | Biologically active cluster of molecules |
-
2021
- 2021-06-23 AU AU2021296983A patent/AU2021296983A1/en active Pending
- 2021-06-23 EP EP25178184.5A patent/EP4596052A3/en active Pending
- 2021-06-23 WO PCT/NL2021/050394 patent/WO2021261998A1/en not_active Ceased
- 2021-06-23 EP EP21734544.6A patent/EP4171643B1/en active Active
- 2021-06-23 CA CA3183881A patent/CA3183881A1/en active Pending
- 2021-06-23 IL IL299349A patent/IL299349A/en unknown
- 2021-06-23 KR KR1020237002644A patent/KR20230044196A/ko active Pending
- 2021-06-23 US US18/012,778 patent/US20230293562A1/en active Pending
- 2021-06-23 CN CN202180052532.8A patent/CN116194148A/zh active Pending
- 2021-06-23 JP JP2022580238A patent/JP2023533693A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPH10501237A (ja) | オリゴヌクレオチドのためのシクロデキストリン細胞送達系 | |
| TW202540423A (zh) | 用於抑制17β-HSD第13型(HSD17B13)表現之RNAi藥劑、其組合物及使用方法 | |
| US20070060499A1 (en) | Chloroquine combination drugs and methods for their synthesis | |
| JP2023533693A5 (https=) | ||
| AU2013262415B2 (en) | Oligonucleotide chelate complex methods | |
| EP4355369B1 (en) | Conjugate of saponin, oligonucleotide and galnac | |
| CN113454221A (zh) | 含有三元环的双链核酸抑制剂分子 | |
| TW202113081A (zh) | 用於治療α-1抗胰蛋白酶缺乏症(AATD)的方法 | |
| US20080051323A1 (en) | Chloroquine drug compositions and methods for their synthesis | |
| KR20230043114A (ko) | Galnac과 사포닌의 접합체, 상기 접합체 및 galnac-올리고뉴클레오티드 접합체를 포함하는 치료적 조성물 | |
| JP2023532040A5 (https=) | ||
| JP2023532681A5 (https=) | ||
| JP2022542075A5 (https=) | ||
| JP2023542500A5 (https=) | ||
| EP4171643B1 (en) | Therapeutic combination of galnac-oligonucleotide conjugate and saponin, and uses thereof | |
| WO2023208109A1 (zh) | 用于抑制HSD17B13表达的siRNA、其缀合物和药物组合物及其用途 | |
| TW202237189A (zh) | 具有增強之肝靶向的ｓ抗原運輸抑制寡核苷酸聚合物之接合物 | |
| JP2023532679A5 (https=) | ||
| EP4210760B1 (en) | Conjugate of saponin, oligonucleotide and galnac | |
| WO2006123631A1 (ja) | Ｒｎａ含有組成物 | |
| HK40128805A (en) | Therapeutic combination of galnac-oligonucleotide conjugate and saponin, and uses thereof | |
| HK40110483A (en) | Conjugate of saponin, oligonucleotide and galnac | |
| HK40110483B (en) | Conjugate of saponin, oligonucleotide and galnac | |
| HK40124033A (en) | Conjugate of saponin, oligonucleotide and galnac | |
| HK40129944A (zh) | Galnac和皂苷的缀合物、包含所述缀合物和galnac-寡核苷酸缀合物的治疗性组合物 |