JP2023532040A5 - - Google Patents
Info
- Publication number
- JP2023532040A5 JP2023532040A5 JP2022580236A JP2022580236A JP2023532040A5 JP 2023532040 A5 JP2023532040 A5 JP 2023532040A5 JP 2022580236 A JP2022580236 A JP 2022580236A JP 2022580236 A JP2022580236 A JP 2022580236A JP 2023532040 A5 JP2023532040 A5 JP 2023532040A5
- Authority
- JP
- Japan
- Prior art keywords
- saponin
- xyl
- rha
- fuc
- conjugate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL2025899 | 2020-06-24 | ||
| NL2025899 | 2020-06-24 | ||
| NL2026442 | 2020-09-10 | ||
| NL2026442 | 2020-09-10 | ||
| PCT/NL2021/050384 WO2021261992A1 (en) | 2020-06-24 | 2021-06-18 | Conjugate of galnac and saponin, therapeutic composition comprising said conjugate and a galnac-oligonucleotide conjugate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023532040A JP2023532040A (ja) | 2023-07-26 |
| JP2023532040A5 true JP2023532040A5 (https=) | 2024-06-25 |
Family
ID=85176234
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022580236A Pending JP2023532040A (ja) | 2020-06-24 | 2021-06-18 | ＧａｌＮＡｃ及びサポニンのコンジュゲート、前記コンジュゲート及びＧａｌＮＡｃ－オリゴヌクレオチドコンジュゲートを含む治療組成物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230263897A1 (https=) |
| EP (2) | EP4438125A3 (https=) |
| JP (1) | JP2023532040A (https=) |
| KR (1) | KR20230043114A (https=) |
| CN (2) | CN116234582A (https=) |
| AU (1) | AU2021295358B2 (https=) |
| CA (1) | CA3183885A1 (https=) |
| ES (1) | ES3002193T3 (https=) |
| IL (1) | IL299357A (https=) |
| MX (1) | MX2023000092A (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021001646A2 (en) * | 2019-07-02 | 2021-01-07 | Argonaute RNA Limited | Apolipoprotein b antagonist |
| WO2025016444A1 (en) * | 2023-07-20 | 2025-01-23 | Shanghai Argo Biopharmaceutical Co., Ltd. | Compositions and methods for inhibiting expression of pd-l1 |
| CN116655715B (zh) * | 2023-07-27 | 2023-10-20 | 北京炫景瑞医药科技有限公司 | 一种GalNAc衍生物、缀合物、组合物以及它们的用途 |
| CN116854754B (zh) * | 2023-09-01 | 2023-12-12 | 北京悦康科创医药科技股份有限公司 | 一种含有核糖环或其衍生结构的GalNAc化合物及其寡核苷酸缀合物 |
| WO2025090612A1 (en) * | 2023-10-27 | 2025-05-01 | Wisconsin Alumni Research Foundation | Lipid nanoparticles formed by lipidoids for efficient delivery of nucleotide drugs and biologics |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004041310A1 (en) * | 2002-11-08 | 2004-05-21 | Danmarks Fødevareforskning | Preparation of chemically well-defined carbohydrate dendrimer conjugates |
| EP1623715B1 (en) * | 2004-07-13 | 2012-09-19 | Charité - Universitätsmedizin Berlin | A composition comprising a pharmacologically active agent coupled to a target cell specific component, and a saponin |
| WO2008007941A1 (en) * | 2006-07-10 | 2008-01-17 | Vereniging Voor Christelijk Wetenschappelijk Onderwijs | Gainac specific binding molecules and uses thereof |
| WO2011054811A1 (en) | 2009-11-03 | 2011-05-12 | Santaris Pharma A/S | Rna antagonists targeting hsp27 combination therapy |
| WO2011141703A1 (en) * | 2010-05-12 | 2011-11-17 | Protiva Biotherapeutics Inc. | Compositions and methods for silencing apolipoprotein b |
| CA2800911A1 (en) * | 2010-06-11 | 2011-12-15 | University Of Georgia Research Foundation, Inc. | Immunogenic vaccine |
| US20150024037A1 (en) * | 2012-02-16 | 2015-01-22 | The University Of Toledo | Xenoantigen-Displaying Anti-Cancer Vaccines and Method of Making |
| DK2992098T3 (da) * | 2013-05-01 | 2019-06-17 | Ionis Pharmaceuticals Inc | Sammensætninger og fremgangsmåder til modulering af hbv- og ttr-ekspression |
| AR100516A1 (es) * | 2014-05-19 | 2016-10-12 | Pfizer | Compuestos de 6,8-dioxabiciclo[3.2.1]octano-2,3-diol sustituidos como agentes de direccionamiento al asgpr |
| CN106795200B (zh) * | 2014-10-10 | 2020-06-19 | 豪夫迈·罗氏有限公司 | Galnac亚磷酰胺、其核酸缀合物及其用途 |
| EP3514240A1 (en) * | 2018-01-18 | 2019-07-24 | Freie Universität Berlin | Novel uses of a saponin and method for its isolation |
| SG11202106603UA (en) * | 2018-12-21 | 2021-07-29 | Sapreme Tech Bv | Biologically active cluster of molecules |
-
2021
- 2021-06-18 AU AU2021295358A patent/AU2021295358B2/en active Active
- 2021-06-18 ES ES21734241T patent/ES3002193T3/es active Active
- 2021-06-18 US US18/012,769 patent/US20230263897A1/en active Pending
- 2021-06-18 CN CN202180051254.4A patent/CN116234582A/zh active Pending
- 2021-06-18 CA CA3183885A patent/CA3183885A1/en active Pending
- 2021-06-18 EP EP24190153.7A patent/EP4438125A3/en active Pending
- 2021-06-18 IL IL299357A patent/IL299357A/en unknown
- 2021-06-18 MX MX2023000092A patent/MX2023000092A/es unknown
- 2021-06-18 EP EP21734241.9A patent/EP4171641B1/en active Active
- 2021-06-18 KR KR1020237002660A patent/KR20230043114A/ko active Pending
- 2021-06-18 JP JP2022580236A patent/JP2023532040A/ja active Pending
- 2021-06-18 CN CN202510833809.0A patent/CN120586078A/zh active Pending
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