JP2023542500A5 - - Google Patents

Info

Publication number
JP2023542500A5
JP2023542500A5 JP2023516250A JP2023516250A JP2023542500A5 JP 2023542500 A5 JP2023542500 A5 JP 2023542500A5 JP 2023516250 A JP2023516250 A JP 2023516250A JP 2023516250 A JP2023516250 A JP 2023516250A JP 2023542500 A5 JP2023542500 A5 JP 2023542500A5
Authority
JP
Japan
Prior art keywords
saponin
xyl
rha
fuc
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023516250A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023542500A (ja
Filing date
Publication date
Priority claimed from NL2027405A external-priority patent/NL2027405B1/en
Priority claimed from PCT/NL2021/050384 external-priority patent/WO2021261992A1/en
Application filed filed Critical
Priority claimed from PCT/NL2021/050549 external-priority patent/WO2022055351A1/en
Publication of JP2023542500A publication Critical patent/JP2023542500A/ja
Publication of JP2023542500A5 publication Critical patent/JP2023542500A5/ja
Pending legal-status Critical Current

Links

JP2023516250A 2020-09-10 2021-09-09 サポニン、オリゴヌクレオチド、及びgalnacのコンジュゲート Pending JP2023542500A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
NL2026442 2020-09-10
NL2026442 2020-09-10
NL2027405 2021-01-26
NL2027405A NL2027405B1 (en) 2021-01-26 2021-01-26 Semicarbazone-based saponin conjugate
PCT/NL2021/050384 WO2021261992A1 (en) 2020-06-24 2021-06-18 Conjugate of galnac and saponin, therapeutic composition comprising said conjugate and a galnac-oligonucleotide conjugate
NLPCT/NL2021/050384 2021-06-18
PCT/NL2021/050549 WO2022055351A1 (en) 2020-09-10 2021-09-09 Conjugate of saponin, oligonucleotide and galnac

Publications (2)

Publication Number Publication Date
JP2023542500A JP2023542500A (ja) 2023-10-10
JP2023542500A5 true JP2023542500A5 (https=) 2024-09-02

Family

ID=85573705

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023516250A Pending JP2023542500A (ja) 2020-09-10 2021-09-09 サポニン、オリゴヌクレオチド、及びgalnacのコンジュゲート

Country Status (8)

Country Link
US (1) US20240327829A1 (https=)
EP (2) EP4529953A3 (https=)
JP (1) JP2023542500A (https=)
KR (1) KR20230066384A (https=)
CN (1) CN116437965A (https=)
AU (1) AU2021339332A1 (https=)
CA (1) CA3192469A1 (https=)
IL (1) IL301214A (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117244054B (zh) * 2023-10-16 2024-06-07 国药中生生物技术研究院有限公司 具有螺甾烷-O-gal结构的化合物的佐剂用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1623715B1 (en) * 2004-07-13 2012-09-19 Charité - Universitätsmedizin Berlin A composition comprising a pharmacologically active agent coupled to a target cell specific component, and a saponin
WO2011054811A1 (en) * 2009-11-03 2011-05-12 Santaris Pharma A/S Rna antagonists targeting hsp27 combination therapy
MX2016005855A (es) * 2013-11-14 2016-07-13 Roche Innovation Ct Copenhagen As Compuestos de conjugados antisentido de apolipoproteina b (apob).
SG11202106603UA (en) * 2018-12-21 2021-07-29 Sapreme Tech Bv Biologically active cluster of molecules

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