JP2024530839A5 - - Google Patents

Info

Publication number
JP2024530839A5
JP2024530839A5 JP2023578030A JP2023578030A JP2024530839A5 JP 2024530839 A5 JP2024530839 A5 JP 2024530839A5 JP 2023578030 A JP2023578030 A JP 2023578030A JP 2023578030 A JP2023578030 A JP 2023578030A JP 2024530839 A5 JP2024530839 A5 JP 2024530839A5
Authority
JP
Japan
Prior art keywords
saponin
oligonucleotide complex
oligonucleotide
saponins
complex according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2023578030A
Other languages
English (en)
Japanese (ja)
Other versions
JP2024530839A (ja
Filing date
Publication date
Priority claimed from PCT/NL2021/050384 external-priority patent/WO2021261992A1/en
Priority claimed from PCT/NL2021/050549 external-priority patent/WO2022055351A1/en
Application filed filed Critical
Priority claimed from PCT/NL2022/050127 external-priority patent/WO2022265493A1/en
Publication of JP2024530839A publication Critical patent/JP2024530839A/ja
Publication of JP2024530839A5 publication Critical patent/JP2024530839A5/ja
Pending legal-status Critical Current

Links

JP2023578030A 2021-06-18 2022-03-08 サポニン、オリゴヌクレオチド、およびＧａｌＮＡｃの複合体 Pending JP2024530839A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
PCT/NL2021/050384 WO2021261992A1 (en) 2020-06-24 2021-06-18 Conjugate of galnac and saponin, therapeutic composition comprising said conjugate and a galnac-oligonucleotide conjugate
NLPCT/NL2021/050384 2021-06-18
NLPCT/NL2021/050549 2021-09-09
PCT/NL2021/050549 WO2022055351A1 (en) 2020-09-10 2021-09-09 Conjugate of saponin, oligonucleotide and galnac
PCT/NL2022/050127 WO2022265493A1 (en) 2021-06-18 2022-03-08 Conjugate of saponin, oligonucleotide and galnac

Publications (2)

Publication Number Publication Date
JP2024530839A JP2024530839A (ja) 2024-08-26
JP2024530839A5 true JP2024530839A5 (https=) 2025-03-13

Family

ID=80785160

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2023578030A Pending JP2024530839A (ja) 2021-06-18 2022-03-08 サポニン、オリゴヌクレオチド、およびＧａｌＮＡｃの複合体

Country Status (4)

Country Link
US (1) US20240307545A1 (https=)
EP (2) EP4355369B1 (https=)
JP (1) JP2024530839A (https=)
WO (1) WO2022265493A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN118356506A (zh) * 2023-01-17 2024-07-19 中国科学院上海药物研究所 去唾液酸糖蛋白受体配体与细胞毒素的偶联物及其应用
GB202300865D0 (en) * 2023-01-20 2023-03-08 Proqr Therapeutics Ii Bv Delivery of oligonucleotides
WO2024235273A1 (zh) * 2023-05-15 2024-11-21 成都社泰医疗科技有限公司 多靶向化合物及其应用
AU2024312000A1 (en) * 2023-06-21 2026-02-05 Sapreme Technologies B.V. Pharmaceutical compositions for treatment of central nervous system disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011054811A1 (en) * 2009-11-03 2011-05-12 Santaris Pharma A/S Rna antagonists targeting hsp27 combination therapy
MX2016005855A (es) * 2013-11-14 2016-07-13 Roche Innovation Ct Copenhagen As Compuestos de conjugados antisentido de apolipoproteina b (apob).
SG11202106603UA (en) * 2018-12-21 2021-07-29 Sapreme Tech Bv Biologically active cluster of molecules
WO2022055351A1 (en) * 2020-09-10 2022-03-17 Sapreme Technologies B.V. Conjugate of saponin, oligonucleotide and galnac

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