JP2022542075A5 - - Google Patents
Info
- Publication number
- JP2022542075A5 JP2022542075A5 JP2022504265A JP2022504265A JP2022542075A5 JP 2022542075 A5 JP2022542075 A5 JP 2022542075A5 JP 2022504265 A JP2022504265 A JP 2022504265A JP 2022504265 A JP2022504265 A JP 2022504265A JP 2022542075 A5 JP2022542075 A5 JP 2022542075A5
- Authority
- JP
- Japan
- Prior art keywords
- xyl
- rha
- fuc
- saponin
- saponin derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2026004618A JP2026065112A (ja) | 2019-07-25 | 2026-01-14 | 改良された治療濃度域をもつサポニン誘導体 |
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL2023568 | 2019-07-25 | ||
| NL2023568 | 2019-07-25 | ||
| PCT/EP2019/084290 WO2020126626A1 (en) | 2018-12-21 | 2019-12-09 | Biologically active cluster of molecules |
| PCT/EP2019/084292 WO2020126627A1 (en) | 2018-12-21 | 2019-12-09 | Improved cell-targeting binding molecule |
| EPPCT/EP2019/084292 | 2019-12-09 | ||
| PCT/EP2019/084210 WO2020126609A2 (en) | 2018-12-21 | 2019-12-09 | Drug conjugate |
| EPPCT/EP2019/084290 | 2019-12-09 | ||
| EPPCT/EP2019/084210 | 2019-12-09 | ||
| NL2025904 | 2020-06-24 | ||
| NL2025904 | 2020-06-24 | ||
| PCT/EP2020/071045 WO2021014019A1 (en) | 2019-07-25 | 2020-07-24 | Saponin derivatives with improved therapeutic window |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2026004618A Division JP2026065112A (ja) | 2019-07-25 | 2026-01-14 | 改良された治療濃度域をもつサポニン誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022542075A JP2022542075A (ja) | 2022-09-29 |
| JP2022542075A5 true JP2022542075A5 (https=) | 2023-08-01 |
| JP7807366B2 JP7807366B2 (ja) | 2026-01-27 |
Family
ID=74193344
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022504265A Active JP7807366B2 (ja) | 2019-07-25 | 2020-07-24 | 改良された治療濃度域をもつサポニン誘導体 |
| JP2026004618A Pending JP2026065112A (ja) | 2019-07-25 | 2026-01-14 | 改良された治療濃度域をもつサポニン誘導体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2026004618A Pending JP2026065112A (ja) | 2019-07-25 | 2026-01-14 | 改良された治療濃度域をもつサポニン誘導体 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20230357310A1 (https=) |
| EP (2) | EP4003427B1 (https=) |
| JP (2) | JP7807366B2 (https=) |
| KR (1) | KR20220038744A (https=) |
| CN (1) | CN114222750B (https=) |
| AU (2) | AU2020316679B2 (https=) |
| BR (1) | BR112022001389A8 (https=) |
| CA (1) | CA3146481A1 (https=) |
| DK (1) | DK4003427T3 (https=) |
| ES (1) | ES3056941T3 (https=) |
| IL (2) | IL316853A (https=) |
| MX (1) | MX2022001066A (https=) |
| PT (1) | PT4003427T (https=) |
| WO (1) | WO2021014019A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11202106603UA (en) | 2018-12-21 | 2021-07-29 | Sapreme Tech Bv | Biologically active cluster of molecules |
| CN111198236A (zh) * | 2020-01-14 | 2020-05-26 | 山东中医药大学 | 利用高效液相色谱和液质联用色谱鉴别金银花和山银花的方法 |
| KR20230043118A (ko) * | 2020-06-24 | 2023-03-30 | 사프렘 테크놀로지스 비.브이. | 사포닌 및 단일-도메인 항체의 접합체, 상기 접합체를 포함하는 약학적 조성물, 이의 치료 용도 |
| KR20230044195A (ko) * | 2020-06-24 | 2023-04-03 | 사프렘 테크놀로지스 비.브이. | 항체-약물 접합체와 항체-사포닌 접합체의 조합물 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5583112A (en) * | 1987-05-29 | 1996-12-10 | Cambridge Biotech Corporation | Saponin-antigen conjugates and the use thereof |
| WO2004092329A2 (en) * | 2003-04-08 | 2004-10-28 | Galenica Pharmaceuticals, Inc. | Semi-synthetic saponin analogs with carrier and immune stimulatory activities for dna and rna vaccines |
| KR102424785B1 (ko) * | 2014-05-30 | 2022-07-25 | 메모리얼 슬로안 케터링 캔서 센터 | 최소 사포닌 유사체, 이의 합성법 및 용도 |
| WO2018057031A1 (en) * | 2016-09-26 | 2018-03-29 | Natural Response, S.A. | Production of biomass in ultra high density plantations |
| US11708388B2 (en) * | 2017-07-11 | 2023-07-25 | Freie Universität Berlin | Uses of a saponin and method for its isolation |
| SG11202106603UA (en) * | 2018-12-21 | 2021-07-29 | Sapreme Tech Bv | Biologically active cluster of molecules |
-
2020
- 2020-07-24 ES ES20746624T patent/ES3056941T3/es active Active
- 2020-07-24 CN CN202080053651.0A patent/CN114222750B/zh active Active
- 2020-07-24 KR KR1020227006246A patent/KR20220038744A/ko active Pending
- 2020-07-24 JP JP2022504265A patent/JP7807366B2/ja active Active
- 2020-07-24 EP EP20746624.4A patent/EP4003427B1/en active Active
- 2020-07-24 EP EP25195993.8A patent/EP4635501A3/en active Pending
- 2020-07-24 AU AU2020316679A patent/AU2020316679B2/en active Active
- 2020-07-24 BR BR112022001389A patent/BR112022001389A8/pt not_active Application Discontinuation
- 2020-07-24 PT PT207466244T patent/PT4003427T/pt unknown
- 2020-07-24 IL IL316853A patent/IL316853A/en unknown
- 2020-07-24 WO PCT/EP2020/071045 patent/WO2021014019A1/en not_active Ceased
- 2020-07-24 CA CA3146481A patent/CA3146481A1/en active Pending
- 2020-07-24 MX MX2022001066A patent/MX2022001066A/es unknown
- 2020-07-24 IL IL290060A patent/IL290060B2/en unknown
- 2020-07-24 US US17/629,796 patent/US20230357310A1/en active Pending
- 2020-07-24 DK DK20746624.4T patent/DK4003427T3/da active
-
2025
- 2025-10-01 AU AU2025242163A patent/AU2025242163A1/en active Pending
-
2026
- 2026-01-14 JP JP2026004618A patent/JP2026065112A/ja active Pending
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