JP2023516951A5 - - Google Patents

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Publication number
JP2023516951A5
JP2023516951A5 JP2022551616A JP2022551616A JP2023516951A5 JP 2023516951 A5 JP2023516951 A5 JP 2023516951A5 JP 2022551616 A JP2022551616 A JP 2022551616A JP 2022551616 A JP2022551616 A JP 2022551616A JP 2023516951 A5 JP2023516951 A5 JP 2023516951A5
Authority
JP
Japan
Prior art keywords
pharmaceutically acceptable
cancer
alpelisib
oxyphenyl
fluoropropyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022551616A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023516951A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2021/054815 external-priority patent/WO2021170793A1/en
Publication of JP2023516951A publication Critical patent/JP2023516951A/ja
Publication of JP2023516951A5 publication Critical patent/JP2023516951A5/ja
Pending legal-status Critical Current

Links

JP2022551616A 2020-02-27 2021-02-26 アルペリシブおよび6-(2,4-ジクロロフェニル)-5-[4-[(3s)-1-(3-フルオロプロピル)ピロリジン-3-イル]オキシフェニル]-8,9-ジヒドロ-7h-ベンゾ[7]アヌレン-2-カルボン酸を含む組合せ物 Pending JP2023516951A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20305190 2020-02-27
EP20305190.9 2020-02-27
PCT/EP2021/054815 WO2021170793A1 (en) 2020-02-27 2021-02-26 Combination comprising alpelisib and 6-(2,4-dichlorophenyl)-5-[4-[(3s)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7h-benzo[7]annulene-2-carboxylic acid

Publications (2)

Publication Number Publication Date
JP2023516951A JP2023516951A (ja) 2023-04-21
JP2023516951A5 true JP2023516951A5 (https=) 2024-02-27

Family

ID=69784379

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022551616A Pending JP2023516951A (ja) 2020-02-27 2021-02-26 アルペリシブおよび6-(2,4-ジクロロフェニル)-5-[4-[(3s)-1-(3-フルオロプロピル)ピロリジン-3-イル]オキシフェニル]-8,9-ジヒドロ-7h-ベンゾ[7]アヌレン-2-カルボン酸を含む組合せ物

Country Status (13)

Country Link
US (1) US12427142B2 (https=)
EP (1) EP4110326B1 (https=)
JP (1) JP2023516951A (https=)
KR (1) KR20220146473A (https=)
CN (1) CN115209893B (https=)
AR (1) AR121589A1 (https=)
AU (1) AU2021227007A1 (https=)
BR (1) BR112022015972A2 (https=)
CA (1) CA3168936A1 (https=)
IL (1) IL295807A (https=)
MX (1) MX2022010539A (https=)
TW (1) TW202146007A (https=)
WO (1) WO2021170793A1 (https=)

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BR112021003440A2 (pt) 2018-09-07 2021-05-18 Sanofi sais de 6-(2,4-diclorofenil)-5-[4-[(3s)-1-(3-fluoropropil) pirrolidin-3-il]oxifenil]-8,9-di-hidro-7h-benzo[7]anuleno-2-carboxilato de metila e seu processo de preparação
EP4037768B1 (en) 2019-10-01 2023-10-11 Sanofi Novel substituted 6,7-dihydro-5h-benzo[7]annulene compounds, processes for their preparation and therapeutic uses thereof
AU2020399168A1 (en) 2019-12-09 2022-07-28 Sanofi Crystalline form of a 7H-benzo[7]annulene-2-carboxylic acid derivative
TW202233572A (zh) 2020-10-19 2022-09-01 法商賽諾菲公司 新穎之經取代的6,7-二氫-5h-苯並[7]輪烯衍生物,其製備方法及其治療用途
WO2022084280A1 (en) 2020-10-19 2022-04-28 Sanofi Substituted 6,7-dihydro-5h-benzo[7]annulene compounds and their derivatives, processes for their preparation and therapeutic uses thereof
TW202543650A (zh) 2024-03-08 2025-11-16 美商海爾達醫療運營公司 異雙官能化合物及其在治療疾病中之用途

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