JP2023550149A5 - - Google Patents
Info
- Publication number
- JP2023550149A5 JP2023550149A5 JP2023530790A JP2023530790A JP2023550149A5 JP 2023550149 A5 JP2023550149 A5 JP 2023550149A5 JP 2023530790 A JP2023530790 A JP 2023530790A JP 2023530790 A JP2023530790 A JP 2023530790A JP 2023550149 A5 JP2023550149 A5 JP 2023550149A5
- Authority
- JP
- Japan
- Prior art keywords
- abemaciclib
- pharmaceutically acceptable
- cancer
- oxyphenyl
- fluoropropyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20315465 | 2020-11-23 | ||
| EP20315465.3 | 2020-11-23 | ||
| PCT/EP2021/082583 WO2022106711A1 (en) | 2020-11-23 | 2021-11-23 | Combination comprising abemaciclib and 6-(2,4-dichlorophenyl)-5-[4-[(3s)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7h-benzo[7]annulene-2-carboxylic acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023550149A JP2023550149A (ja) | 2023-11-30 |
| JP2023550149A5 true JP2023550149A5 (https=) | 2024-11-29 |
Family
ID=73855492
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023530790A Pending JP2023550149A (ja) | 2020-11-23 | 2021-11-23 | アベマシクリブと６－（２，４－ジクロロフェニル）－５－［４－［（３ｓ）－１－（３－フルオロプロピル）ピロリジン－３－イル］オキシフェニル］－８，９－ジヒドロ－７ｈ－ベンゾ［７］アヌレン－２－カルボン酸とを含む組み合わせ |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20230404971A1 (https=) |
| EP (1) | EP4247363A1 (https=) |
| JP (1) | JP2023550149A (https=) |
| KR (1) | KR20230112626A (https=) |
| CN (1) | CN116782895A (https=) |
| AU (1) | AU2021382148A1 (https=) |
| CA (1) | CA3199466A1 (https=) |
| IL (1) | IL303041A (https=) |
| MX (1) | MX2023006020A (https=) |
| WO (1) | WO2022106711A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112021003440A2 (pt) | 2018-09-07 | 2021-05-18 | Sanofi | sais de 6-(2,4-diclorofenil)-5-[4-[(3s)-1-(3-fluoropropil) pirrolidin-3-il]oxifenil]-8,9-di-hidro-7h-benzo[7]anuleno-2-carboxilato de metila e seu processo de preparação |
| EP4037768B1 (en) | 2019-10-01 | 2023-10-11 | Sanofi | Novel substituted 6,7-dihydro-5h-benzo[7]annulene compounds, processes for their preparation and therapeutic uses thereof |
| AU2020399168A1 (en) | 2019-12-09 | 2022-07-28 | Sanofi | Crystalline form of a 7H-benzo[7]annulene-2-carboxylic acid derivative |
| TW202146007A (zh) | 2020-02-27 | 2021-12-16 | 法商賽諾菲公司 | 包含阿培利司（ａｌｐｅｌｉｓｉｂ）與６－（２，４－二氯苯基）－５－［４－［（３ｓ）－１－（３－氟丙基）吡咯啶－３－基］氧苯基］－８，９－二氫－７ｈ－苯并［７］輪烯－２－羧酸之組合 |
| TW202233572A (zh) | 2020-10-19 | 2022-09-01 | 法商賽諾菲公司 | 新穎之經取代的6,7-二氫-5h-苯並[7]輪烯衍生物，其製備方法及其治療用途 |
| WO2022084280A1 (en) | 2020-10-19 | 2022-04-28 | Sanofi | Substituted 6,7-dihydro-5h-benzo[7]annulene compounds and their derivatives, processes for their preparation and therapeutic uses thereof |
| TW202543650A (zh) | 2024-03-08 | 2025-11-16 | 美商海爾達醫療運營公司 | 異雙官能化合物及其在治療疾病中之用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA034994B1 (ru) * | 2016-02-15 | 2020-04-15 | Санофи | 6,7-дигидро-5h-бензо[7]аннуленовые производные в качестве модуляторов эстрогеновых рецепторов |
| EP3434272A1 (en) * | 2017-07-25 | 2019-01-30 | Sanofi | Combination comprising palbociclib and 6-(2,4-dichlorophenyl)-5-[4-[(3s)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7h-benzo[7]annulene-2-carboxylic acid |
| TWI702219B (zh) * | 2018-07-12 | 2020-08-21 | 美商美國禮來大藥廠 | 選擇性雌激素受體降解劑 |
| MX2021005876A (es) * | 2018-11-30 | 2021-07-16 | Radius Pharmaceuticals Inc | Elacestrant en combinacion con abemaciclib en mujeres con cancer de mama. |
| CA3146346A1 (en) * | 2019-05-09 | 2020-11-12 | Sanofi | 6-(2,4-dichlorophenyl)-5-[4-[(3s)-1-(3-fluoropropyl)pyrrolidin-3-yl]oxyphenyl]-8,9-dihydro-7h-benzo[7]annulene-2-carboxylic acid for use in metastatic or advanced breast cancer patients |
-
2021
- 2021-11-23 WO PCT/EP2021/082583 patent/WO2022106711A1/en not_active Ceased
- 2021-11-23 MX MX2023006020A patent/MX2023006020A/es unknown
- 2021-11-23 AU AU2021382148A patent/AU2021382148A1/en not_active Abandoned
- 2021-11-23 IL IL303041A patent/IL303041A/en unknown
- 2021-11-23 CA CA3199466A patent/CA3199466A1/en active Pending
- 2021-11-23 EP EP21814787.4A patent/EP4247363A1/en active Pending
- 2021-11-23 JP JP2023530790A patent/JP2023550149A/ja active Pending
- 2021-11-23 KR KR1020237017061A patent/KR20230112626A/ko active Pending
- 2021-11-23 US US18/037,949 patent/US20230404971A1/en active Pending
- 2021-11-23 CN CN202180091417.1A patent/CN116782895A/zh active Pending
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