MX2021005876A - Elacestrant en combinacion con abemaciclib en mujeres con cancer de mama. - Google Patents

Elacestrant en combinacion con abemaciclib en mujeres con cancer de mama.

Info

Publication number
MX2021005876A
MX2021005876A MX2021005876A MX2021005876A MX2021005876A MX 2021005876 A MX2021005876 A MX 2021005876A MX 2021005876 A MX2021005876 A MX 2021005876A MX 2021005876 A MX2021005876 A MX 2021005876A MX 2021005876 A MX2021005876 A MX 2021005876A
Authority
MX
Mexico
Prior art keywords
breast cancer
elacestrant
abemaciclib
combination
women
Prior art date
Application number
MX2021005876A
Other languages
English (en)
Inventor
Nina K Aragam
Charles Morris
Original Assignee
Radius Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Radius Pharmaceuticals Inc filed Critical Radius Pharmaceuticals Inc
Publication of MX2021005876A publication Critical patent/MX2021005876A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente descripción se refiere a métodos para tratar el cáncer de mama en un paciente, que comprenden administrar al paciente una combinación terapéutica que comprende elacestrant, o una sal farmacéuticamente aceptable del mismo, y abemaciclib, o una sal farmacéuticamente aceptable del mismo. La presente descripción también se refiere a métodos para tratar el cáncer de mama en un paciente, que producen un tiempo de supervivencia libre de progresión más prolongado en comparación con otros tratamientos.
MX2021005876A 2018-11-30 2019-11-26 Elacestrant en combinacion con abemaciclib en mujeres con cancer de mama. MX2021005876A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862773960P 2018-11-30 2018-11-30
PCT/US2019/063239 WO2020112765A1 (en) 2018-11-30 2019-11-26 Elacestrant in combination with abemaciclib in women with breast cancer

Publications (1)

Publication Number Publication Date
MX2021005876A true MX2021005876A (es) 2021-07-16

Family

ID=68966023

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021005876A MX2021005876A (es) 2018-11-30 2019-11-26 Elacestrant en combinacion con abemaciclib en mujeres con cancer de mama.

Country Status (15)

Country Link
US (1) US20220117963A1 (es)
EP (1) EP3886826A1 (es)
JP (1) JP2022509262A (es)
KR (1) KR20210097170A (es)
CN (1) CN113164415A (es)
AU (1) AU2019388900A1 (es)
BR (1) BR112021010169A2 (es)
CA (1) CA3120368A1 (es)
EA (1) EA202191165A1 (es)
IL (1) IL283502A (es)
MA (1) MA54293A (es)
MX (1) MX2021005876A (es)
PH (1) PH12021551235A1 (es)
SG (1) SG11202105455RA (es)
WO (1) WO2020112765A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL303041A (en) * 2020-11-23 2023-07-01 Sanofi Sa Combinations containing abamciclib, and 6-(2,4-DICHLOROPHENYL)-5-[4-[(3S)-1-(3-FLUOROPROPYL)PYRROLIDIN-3-YL]OXYPHENYL]-8,9-DIHYDRO-7H-BENZO [7]ANNULENE-2-CARBOXYLIC ACID
CN114146182A (zh) * 2021-11-12 2022-03-08 深圳大学 Cdk4/6抑制剂与铂类化疗药物在制备治疗肿瘤的药物中的用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2016256470B2 (en) * 2015-04-29 2020-10-15 Radius Pharmaceuticals, Inc. Methods of treating cancer
MX2018011054A (es) * 2016-03-15 2019-01-21 Merrimack Pharmaceuticals Inc Metodos para tratar cancer de mama er+, her2-, hrg+ usando terapias de combinacion que comprenden un anticuerpo anti-erbb3.
WO2018017410A1 (en) * 2016-07-22 2018-01-25 Eli Lilly And Company Combination therapy of abemaciclib and a pi3 kinase/mtor dual inhibitor for use in the treatment of breast cancer

Also Published As

Publication number Publication date
IL283502A (en) 2021-07-29
EP3886826A1 (en) 2021-10-06
EA202191165A1 (ru) 2021-09-21
KR20210097170A (ko) 2021-08-06
CN113164415A (zh) 2021-07-23
MA54293A (fr) 2021-10-06
BR112021010169A2 (pt) 2021-08-17
JP2022509262A (ja) 2022-01-20
WO2020112765A1 (en) 2020-06-04
PH12021551235A1 (en) 2021-12-13
AU2019388900A1 (en) 2021-06-10
US20220117963A1 (en) 2022-04-21
CA3120368A1 (en) 2020-06-04
SG11202105455RA (en) 2021-06-29

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