MX2022000143A - Metodos novedosos. - Google Patents

Metodos novedosos.

Info

Publication number
MX2022000143A
MX2022000143A MX2022000143A MX2022000143A MX2022000143A MX 2022000143 A MX2022000143 A MX 2022000143A MX 2022000143 A MX2022000143 A MX 2022000143A MX 2022000143 A MX2022000143 A MX 2022000143A MX 2022000143 A MX2022000143 A MX 2022000143A
Authority
MX
Mexico
Prior art keywords
novel methods
lumateperone
bipolar
disorder
administering
Prior art date
Application number
MX2022000143A
Other languages
English (en)
Inventor
Sharon Mates
Kimberly Vanover
Robert Davis
Original Assignee
Intra Cellular Therapies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intra Cellular Therapies Inc filed Critical Intra Cellular Therapies Inc
Publication of MX2022000143A publication Critical patent/MX2022000143A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La descripción proporciona métodos para el tratamiento del trastorno bipolar II, que comprende administrar a un paciente en necesidad de la misma, una cantidad efectiva terapéuticamente de lumateperona, en forma libre o de sal aceptable farmacéuticamente, opcionalmente en forma deuterada.
MX2022000143A 2019-07-07 2020-07-07 Metodos novedosos. MX2022000143A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962871170P 2019-07-07 2019-07-07
PCT/US2020/041063 WO2021007245A1 (en) 2019-07-07 2020-07-07 Novel methods

Publications (1)

Publication Number Publication Date
MX2022000143A true MX2022000143A (es) 2022-02-17

Family

ID=74066254

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2022000143A MX2022000143A (es) 2019-07-07 2020-07-07 Metodos novedosos.

Country Status (11)

Country Link
US (2) US20210000822A1 (es)
EP (2) EP4134101A1 (es)
JP (1) JP2022539821A (es)
KR (1) KR20220029744A (es)
CN (1) CN114072150A (es)
AU (1) AU2020311894A1 (es)
BR (1) BR112022000231A2 (es)
CA (1) CA3141223A1 (es)
IL (1) IL289589A (es)
MX (1) MX2022000143A (es)
WO (1) WO2021007245A1 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3186537A1 (en) * 2020-09-04 2022-03-10 Peng Li Novel salts, crystals, and co-crystals
WO2024030835A2 (en) * 2022-07-30 2024-02-08 Intra-Cellular Therapies, Inc. Novel salts and crystals
CN115671057A (zh) * 2022-10-19 2023-02-03 四川迈可隆生物科技有限公司 一种卢美哌隆药物组合物、长效微球缓释制剂及其制备方法
CN115554237B (zh) * 2022-12-08 2023-09-12 山东则正医药技术有限公司 一种卢美哌隆原位凝胶长效注射剂及其制备方法和用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE52535B1 (en) 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
US6713471B1 (en) 1999-06-15 2004-03-30 Bristol-Myers Squibb Pharma Company Substituted heterocycle fused gamma-carbolines
AU5737900A (en) 1999-06-15 2001-01-02 Du Pont Pharmaceuticals Company Substituted heterocycle fused gamma-carbolines
PL2262505T3 (pl) 2008-03-12 2015-04-30 Intra Cellular Therapies Inc Podstawione heterocykliczne skondensowane gamma-karboliny w postaci stałej
US8598119B2 (en) 2008-05-27 2013-12-03 Intra-Cellular Therapies, Inc. Methods and compositions for sleep disorders and other disorders
EP2560676B8 (en) 2010-04-22 2016-10-12 Intra-Cellular Therapies, Inc. Organic compounds
CA2870303A1 (en) 2012-04-14 2013-10-17 Intra-Cellular Therapies, Inc. Organic compounds
KR20230058736A (ko) * 2013-12-03 2023-05-03 인트라-셀룰라 써래피스, 인코퍼레이티드. 신규한 방법
JP2017509677A (ja) * 2014-04-04 2017-04-06 イントラ−セルラー・セラピーズ・インコーポレイテッドＩｎｔｒａ−Ｃｅｌｌｕｌａｒ Ｔｈｅｒａｐｉｅｓ， Ｉｎｃ． 有機化合物
EP3125893B1 (en) 2014-04-04 2023-09-20 Intra-Cellular Therapies, Inc. Deuterated heterocycle fused gamma-carbolines as antagonists of 5-ht2a receptors
WO2017117514A1 (en) * 2015-12-31 2017-07-06 Tung Roger D Deuterated iti-007
IL297676B2 (en) 2016-03-25 2023-12-01 Intra Cellular Therapies Inc A controlled or delayed release pharmaceutical preparation containing a deuterated compound
HUE057055T2 (hu) * 2016-08-09 2022-04-28 Teva Pharmaceuticals Int Gmbh Lumateperon-ditozilátsó szilárd halmazállapotú formái
AU2019280850A1 (en) 2018-06-06 2021-01-07 Intra-Cellular Therapies, Inc. Novel salts and crystals

Also Published As

Publication number Publication date
EP3993798A4 (en) 2023-04-26
IL289589A (en) 2022-03-01
CN114072150A (zh) 2022-02-18
WO2021007245A1 (en) 2021-01-14
EP3993798A1 (en) 2022-05-11
CA3141223A1 (en) 2021-01-14
US20240066030A1 (en) 2024-02-29
AU2020311894A1 (en) 2022-01-27
JP2022539821A (ja) 2022-09-13
US20210000822A1 (en) 2021-01-07
EP4134101A1 (en) 2023-02-15
KR20220029744A (ko) 2022-03-08
BR112022000231A2 (pt) 2022-02-22

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