JP2023516640A5 - - Google Patents
Info
- Publication number
- JP2023516640A5 JP2023516640A5 JP2022552324A JP2022552324A JP2023516640A5 JP 2023516640 A5 JP2023516640 A5 JP 2023516640A5 JP 2022552324 A JP2022552324 A JP 2022552324A JP 2022552324 A JP2022552324 A JP 2022552324A JP 2023516640 A5 JP2023516640 A5 JP 2023516640A5
- Authority
- JP
- Japan
- Prior art keywords
- lung
- crystalline hydrate
- pharmaceutical composition
- transplant rejection
- disease
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US202062983931P | 2020-03-02 | 2020-03-02 | |
| US62/983,931 | 2020-03-02 | ||
| PCT/US2021/070207 WO2021178991A1 (en) | 2020-03-02 | 2021-03-01 | Crystalline hydrate of a jak inhibitor compound |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023516640A JP2023516640A (ja) | 2023-04-20 |
| JP2023516640A5 true JP2023516640A5 (https=) | 2024-02-14 |
| JP7681613B2 JP7681613B2 (ja) | 2025-05-22 |
Family
ID=75143791
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022552324A Active JP7681613B2 (ja) | 2020-03-02 | 2021-03-01 | Ｊａｋ阻害剤化合物の結晶性水和物 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US11702415B2 (https=) |
| EP (1) | EP4114836B1 (https=) |
| JP (1) | JP7681613B2 (https=) |
| KR (1) | KR20220149585A (https=) |
| CN (1) | CN115190878B (https=) |
| AR (1) | AR121483A1 (https=) |
| AU (1) | AU2021232100A1 (https=) |
| BR (1) | BR112022017398A2 (https=) |
| CA (1) | CA3172338A1 (https=) |
| CL (1) | CL2022002368A1 (https=) |
| CO (1) | CO2022012476A2 (https=) |
| IL (1) | IL295613A (https=) |
| MX (1) | MX2022010795A (https=) |
| PH (1) | PH12022552261A1 (https=) |
| TW (1) | TW202144343A (https=) |
| WO (1) | WO2021178991A1 (https=) |
| ZA (1) | ZA202209617B (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI3837258T3 (fi) * | 2018-09-04 | 2024-05-27 | Theravance Biopharma R&D Ip Llc | Dimetyyliaminoatsetidiiniamideja jak-estäjinä |
| TW202144343A (zh) * | 2020-03-02 | 2021-12-01 | 美商施萬生物製藥研發 Ip有限責任公司 | Jak抑制劑化合物之結晶水合物 |
| US20230381280A1 (en) * | 2020-12-04 | 2023-11-30 | Centurion Ilaç Sanayi Ve Ticaret Anonim Sirketi | New dosage regimen for inhaled vasoactive intestinal polypeptide |
| WO2023230236A1 (en) | 2022-05-26 | 2023-11-30 | Theravance Biopharma R&D Ip, Llc | Process for preparing jak inhibitors and intermediates thereof |
| CN116785290B (zh) * | 2023-02-01 | 2024-02-13 | 银谷制药有限责任公司 | 苯环喹溴铵及其异构体在制备眼用制剂中的应用 |
| TW202508595A (zh) | 2023-05-04 | 2025-03-01 | 美商銳新醫藥公司 | 用於ｒａｓ相關疾病或病症之組合療法 |
| US20250049810A1 (en) | 2023-08-07 | 2025-02-13 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| AU2024360465A1 (en) | 2023-10-12 | 2026-04-09 | Revolution Medicines, Inc. | Macrocyclic ras inhibitors |
| WO2025171296A1 (en) | 2024-02-09 | 2025-08-14 | Revolution Medicines, Inc. | Ras inhibitors |
| TW202547461A (zh) | 2024-05-17 | 2025-12-16 | 美商銳新醫藥公司 | Ｒａｓ抑制劑 |
| WO2025255438A1 (en) | 2024-06-07 | 2025-12-11 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2025265060A1 (en) | 2024-06-21 | 2025-12-26 | Revolution Medicines, Inc. | Therapeutic compositions and methods for managing treatment-related effects |
| WO2026006747A1 (en) | 2024-06-28 | 2026-01-02 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026015801A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015790A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015796A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015825A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Use of ras inhibitor for treating pancreatic cancer |
| WO2026050446A1 (en) | 2024-08-29 | 2026-03-05 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026072904A2 (en) | 2024-09-26 | 2026-04-02 | Revolution Medicines, Inc. | Compositions and methods for treating lung cancer |
| CN119438457B (zh) * | 2024-12-18 | 2025-12-02 | 成都迈科康生物科技有限公司 | 一种测定脂质体佐剂中有关物质的方法及其应用 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI262914B (en) | 1999-07-02 | 2006-10-01 | Agouron Pharma | Compounds and pharmaceutical compositions for inhibiting protein kinases |
| EP1648455A4 (en) | 2003-07-23 | 2009-03-04 | Exelixis Inc | MODULATORS OF ALK PROTEIN (ANAPLASTIC LYMPHOMA KINASE) AND METHODS OF USE |
| US20050090529A1 (en) | 2003-07-31 | 2005-04-28 | Pfizer Inc | 3,5 Disubstituted indazole compounds with nitrogen-bearing 5-membered heterocycles, pharmaceutical compositions, and methods for mediating or inhibiting cell proliferation |
| US7884109B2 (en) | 2005-04-05 | 2011-02-08 | Wyeth Llc | Purine and imidazopyridine derivatives for immunosuppression |
| US8648069B2 (en) | 2007-06-08 | 2014-02-11 | Abbvie Inc. | 5-substituted indazoles as kinase inhibitors |
| JP2010111624A (ja) | 2008-11-06 | 2010-05-20 | Shionogi & Co Ltd | Ｔｔｋ阻害作用を有するインダゾール誘導体 |
| WO2010114971A1 (en) | 2009-04-03 | 2010-10-07 | Sepracor Inc. | Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof |
| LT3001903T (lt) | 2009-12-21 | 2018-01-10 | Samumed, Llc | 1h-pirazolo[3,4-b]piridinai ir jų terapinis panaudojimas |
| US8575336B2 (en) | 2011-07-27 | 2013-11-05 | Pfizer Limited | Indazoles |
| SI3077395T1 (en) | 2013-12-05 | 2018-03-30 | Pfizer Inc. | Pyrrolo(2,3-d)pyrimidinyl, pyrrolo(2,3-b)pyrazinyl and pyrrolo(2,3-d)pyridinyl acrylamides |
| KR20170002623A (ko) | 2014-05-14 | 2017-01-06 | 화이자 인코포레이티드 | 피라졸로피리딘 및 피라졸로피리미딘 |
| WO2016026078A1 (en) | 2014-08-19 | 2016-02-25 | Changzhou Jiekai Pharmatech Co., Ltd. | Heterocyclic compounds as erk inhibitors |
| KR101663277B1 (ko) | 2015-03-30 | 2016-10-06 | 주식회사 녹십자 | TNIK, IKKε 및 TBK1 억제제로서의 피라졸계 유도체 및 이를 포함하는 약학적 조성물 |
| WO2017077283A1 (en) | 2015-11-03 | 2017-05-11 | Topivert Pharma Limited | 4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridine and 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepine derivatives as janus kinase inhibitors |
| DK3371185T3 (da) * | 2015-11-03 | 2020-11-30 | Topivert Pharma Ltd | 4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridin og 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepinderivater som janus-kinase-inhibitorer |
| UA123633C2 (uk) | 2015-11-03 | 2021-05-05 | Тереванс Байофарма Ар Енд Ді Айпі, Елелсі | Сполуки інгібітору jak-кінази для лікування респіраторного захворювання |
| US20180258546A1 (en) | 2017-03-09 | 2018-09-13 | Lam Research Corporation | Electroplating apparatus and methods utilizing independent control of impinging electrolyte |
| WO2018165392A1 (en) * | 2017-03-09 | 2018-09-13 | Theravance Biopharma R&D Ip, Llc | Jak inhibitors containing a 4-membered heterocyclic amide |
| WO2018204233A1 (en) | 2017-05-01 | 2018-11-08 | Theravance Biopharma R&D Ip, Llc | Methods of treatment using a jak inhibitor compound |
| AR111495A1 (es) | 2017-05-01 | 2019-07-17 | Theravance Biopharma R&D Ip Llc | Compuestos de imidazo-piperidina fusionada como inhibidores de jak |
| KR20200003121A (ko) | 2017-05-01 | 2020-01-08 | 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 | Jak 저해제 화합물의 결정형 |
| FI3837258T3 (fi) | 2018-09-04 | 2024-05-27 | Theravance Biopharma R&D Ip Llc | Dimetyyliaminoatsetidiiniamideja jak-estäjinä |
| JP2021535176A (ja) | 2018-09-04 | 2021-12-16 | セラヴァンス バイオファーマ アール＆ディー アイピー， エルエルシー | Ｊａｋ阻害剤およびその中間体を調製するためのプロセス |
| UA127328C2 (uk) | 2018-09-04 | 2023-07-19 | Тереванс Байофарма Ар Енд Ді Айпі, Елелсі | 5-7-членні гетероциклічні аміди як інгібітори jak |
| KR20210084512A (ko) | 2018-10-29 | 2021-07-07 | 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 | Jak 억제제로서 2-아자비시클로 헥산 화합물 |
| HUE067145T2 (hu) | 2019-02-25 | 2024-10-28 | Henan Medinno Pharmaceutical Tech Co Ltd | JAK inhibitor vegyület és alkalmazása |
| WO2020181034A1 (en) | 2019-03-05 | 2020-09-10 | Incyte Corporation | Jak1 pathway inhibitors for the treatment of chronic lung allograft dysfunction |
| CN112279848A (zh) | 2019-07-25 | 2021-01-29 | 四川海思科制药有限公司 | 一种泛JAKs抑制剂及其用途 |
| TW202144343A (zh) * | 2020-03-02 | 2021-12-01 | 美商施萬生物製藥研發 Ip有限責任公司 | Jak抑制劑化合物之結晶水合物 |
| CN115803023A (zh) | 2020-05-08 | 2023-03-14 | 施万生物制药研发Ip有限责任公司 | 发用奈珠西替尼治疗感染冠状病毒的患者的方法 |
| WO2022271604A1 (en) | 2021-06-21 | 2022-12-29 | Theravance Biopharma R&D Ip, Llc | Method of treating a patient infected with a coronavirus and having a baseline level of crp below 150 mg/l |
-
2021
- 2021-02-26 TW TW110106884A patent/TW202144343A/zh unknown
- 2021-03-01 CN CN202180017759.9A patent/CN115190878B/zh active Active
- 2021-03-01 AU AU2021232100A patent/AU2021232100A1/en not_active Abandoned
- 2021-03-01 US US17/249,375 patent/US11702415B2/en active Active
- 2021-03-01 KR KR1020227034088A patent/KR20220149585A/ko active Pending
- 2021-03-01 AR ARP210100530A patent/AR121483A1/es unknown
- 2021-03-01 EP EP21713868.4A patent/EP4114836B1/en active Active
- 2021-03-01 JP JP2022552324A patent/JP7681613B2/ja active Active
- 2021-03-01 MX MX2022010795A patent/MX2022010795A/es unknown
- 2021-03-01 WO PCT/US2021/070207 patent/WO2021178991A1/en not_active Ceased
- 2021-03-01 CA CA3172338A patent/CA3172338A1/en active Pending
- 2021-03-01 PH PH1/2022/552261A patent/PH12022552261A1/en unknown
- 2021-03-01 BR BR112022017398A patent/BR112022017398A2/pt unknown
- 2021-03-01 IL IL295613A patent/IL295613A/en unknown
-
2022
- 2022-08-29 ZA ZA2022/09617A patent/ZA202209617B/en unknown
- 2022-08-31 CL CL2022002368A patent/CL2022002368A1/es unknown
- 2022-08-31 CO CONC2022/0012476A patent/CO2022012476A2/es unknown
-
2023
- 2023-05-31 US US18/326,732 patent/US12122773B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2023516640A5 (https=) | ||
| JP2020518581A5 (https=) | ||
| JP2020518582A5 (https=) | ||
| JP2021535177A5 (https=) | ||
| HRP20220330T1 (hr) | Kondenzirani imidazopiperidinski spoj, kao inhibitor jak | |
| KR0184911B1 (ko) | 인돌유도체 | |
| CN116829571A (zh) | 新型螺旋吡咯烷衍生的抗病毒药物 | |
| JP2018531982A5 (https=) | ||
| US9981947B2 (en) | Polymorphic forms of nilotinib hydrochloride | |
| JP5344942B2 (ja) | 多形性形態 | |
| JP2009510140A (ja) | ５−クロロ−ｎ−（｛（５ｓ）−２−オキソ−３−［４−（３−オキソ−４−モルホリニル）−フェニル］−１，３−オキサゾリジン−５−イル｝−メチル）−２−チオフェンカルボキサミドの新規多形および無定形 | |
| TW200528097A (en) | Novel thiazolidin-4-one derivatives | |
| JP2022533340A5 (https=) | ||
| JP2022532404A5 (https=) | ||
| JP2023103328A (ja) | ビランテロールトリフェニル酢酸塩の新規な結晶形態及びこれらの調製プロセス | |
| KR20120098816A (ko) | 메틸｛４，６?디아미노?２?〔１?（２?플루오로벤질）?１ｈ?피라졸로〔３，４?ｂ〕피리딘?３?일〕피리미딘?５?일｝카르바메이트의 신규한 다형체 형상 | |
| JP2007520546A (ja) | モンテルカストナトリウムの安定な非晶質性形態 | |
| JP2022540922A5 (https=) | ||
| CA3133803A1 (en) | Solid forms of (e)-3-[2-(2-thienyl)vinyl]-1h-pyrazole | |
| JP6674967B2 (ja) | 化合物 （ｓ）−３−｛４−［５−（２−シクロペンチル−６−メトキシ−ピリジン−４−イル）−［１，２，４］オキサジアゾール−３−イル］−２−エチル−６−メチル−フェノキシ｝−プロパン−１，２−ジオールの結晶形 | |
| CN116133666A (zh) | 一种硼酸酯衍生物及其用途 | |
| JP2019509286A5 (https=) | ||
| CA2784010A1 (en) | Novel solvates of methyl{4,6-diamino-2-[1-(2-fluorobenzyl)-1h-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate | |
| RU2018135072A (ru) | Кристаллическая (2s,4r)-5-(5'-хлор-2'-фтор-[1,1'-бифенил]-4-ил)-2-(этоксиметил)-4-(3-гидроксиизоксазол-5-карбоксамидо)-2-метилпентановая кислота и ее применения | |
| WO2010111951A1 (zh) | 普拉格雷氢溴酸盐的晶体 |