JP2023514794A5 - - Google Patents
Info
- Publication number
- JP2023514794A5 JP2023514794A5 JP2022576572A JP2022576572A JP2023514794A5 JP 2023514794 A5 JP2023514794 A5 JP 2023514794A5 JP 2022576572 A JP2022576572 A JP 2022576572A JP 2022576572 A JP2022576572 A JP 2022576572A JP 2023514794 A5 JP2023514794 A5 JP 2023514794A5
- Authority
- JP
- Japan
- Prior art keywords
- indazole
- aminocarbonyl
- phenyl
- trifluoroacetate
- benzyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202010111755.4 | 2020-02-24 | ||
| CN202010111755 | 2020-02-24 | ||
| PCT/CN2021/077610 WO2021169984A1 (zh) | 2020-02-24 | 2021-02-24 | 聚adp核糖聚合酶抑制剂在抗冠状病毒中的应用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023514794A JP2023514794A (ja) | 2023-04-10 |
| JP2023514794A5 true JP2023514794A5 (enExample) | 2024-02-19 |
| JP7881489B2 JP7881489B2 (ja) | 2026-06-29 |
Family
ID=77319076
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022576572A Active JP7881489B2 (ja) | 2020-02-24 | 2021-02-24 | ポリａｄｐリボースポリメラーゼ阻害剤の抗コロナウイルス応用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20240016775A1 (enExample) |
| EP (1) | EP4112049A4 (enExample) |
| JP (1) | JP7881489B2 (enExample) |
| CN (1) | CN113288892B (enExample) |
| CA (1) | CA3169303A1 (enExample) |
| WO (1) | WO2021169984A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL300229A (en) * | 2020-07-31 | 2023-03-01 | Univ Alberta | Using beta-catenin/WNT pathway inhibitors to block replication of SARS-COV-2 and other pathogenic viruses |
| CN115554303B (zh) * | 2021-09-18 | 2024-07-09 | 上海科技大学 | 一种三环类化合物、其制备方法及其应用 |
| CN116836173B (zh) * | 2023-08-31 | 2023-12-12 | 甫康（上海）健康科技有限责任公司 | 亚胺酰基酰肼类化合物、含其的组合物和其应用 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5633282A (en) * | 1990-05-25 | 1997-05-27 | British Technology Group Limited | Inhibition of viral infection |
| EP1140936B1 (en) | 1999-01-11 | 2004-03-17 | Agouron Pharmaceuticals, Inc. | Tricyclic inhibitors of poly(adp-ribose) polymerases |
| JP2003528073A (ja) * | 2000-03-20 | 2003-09-24 | エヌ・ジーン リサーチ ラボラトリーズ インコーポレイテッド | プロペンカルボン酸アミドキシム誘導体、その製法、及びこの誘導体を含有する医薬組成物 |
| GB0305681D0 (en) | 2003-03-12 | 2003-04-16 | Kudos Pharm Ltd | Phthalazinone derivatives |
| PL1633724T3 (pl) | 2003-03-12 | 2011-10-31 | Kudos Pharm Ltd | Pochodne ftalazynonu |
| US20060079510A1 (en) * | 2004-09-30 | 2006-04-13 | Kristoffer Hellstrand | Use of PARP-1 inhibitors for protecting tumorcidal lymphocytes from apoptosis |
| US20090275619A1 (en) | 2006-04-03 | 2009-11-05 | BOUERES Julia | Amide Substituted Indazole and Benzotriazole Derivatives as Poly(ADP-Ribose)Polymerase (PARP) Inhibitors |
| GB0700432D0 (en) | 2007-01-10 | 2007-02-21 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
| GB0606663D0 (en) | 2006-04-03 | 2006-05-10 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
| CN103242273B (zh) | 2012-02-09 | 2015-06-03 | 中国科学院上海药物研究所 | 2-芳基苯并呋喃-7-甲酰胺类化合物、其制备方法及用途 |
| CN102627620B (zh) * | 2012-04-10 | 2015-12-16 | 江苏先声药物研究有限公司 | 一类苯并呋喃衍生物及其医药应用 |
| JP6768693B2 (ja) * | 2015-03-30 | 2020-10-14 | キャリセラ バイオサイエンシーズ， インコーポレイテッド | グルタミナーゼ阻害剤を投与する方法 |
| WO2017128036A1 (zh) * | 2016-01-26 | 2017-08-03 | 中国医学科学院药物研究所 | 喹唑啉酮类parp-1抑制剂及其制备方法、药物组合物和用途 |
| KR102030016B1 (ko) * | 2016-09-05 | 2019-10-08 | 충남대학교산학협력단 | 신규한 화합물, 이의 제조방법 및 이를 유효성분으로 함유하는 폴리(adp-리보스)폴리머라제-1(parp-1) 관련 질환의 예방 또는 치료용 약학적 조성물 |
| MA50677A (fr) * | 2016-11-01 | 2021-07-14 | Anaptysbio Inc | Anticorps dirigés contre la protéine d'immunoglobuline de lymphocytes t et mucine 3 (tim-3) |
| CN110049777A (zh) * | 2016-11-01 | 2019-07-23 | 安奈普泰斯生物有限公司 | 针对程序性死亡-1(pd-1)的抗体 |
| TWI791519B (zh) * | 2017-04-27 | 2023-02-11 | 美商提薩羅有限公司 | 針對淋巴細胞活化基因-3（lag-3）之抗體藥劑及其用途 |
| CN110913911A (zh) | 2017-05-18 | 2020-03-24 | 特沙诺有限公司 | 用于治疗癌症的组合疗法 |
| CN109134409B (zh) | 2017-06-14 | 2023-09-29 | 中国科学院上海药物研究所 | 盐酸美呋哌瑞多晶型物及其制备方法与应用 |
| CN110194762B (zh) * | 2018-02-27 | 2021-09-10 | 中国科学院上海药物研究所 | 酞嗪酮类衍生物、其制备方法和用途 |
| CN110241198A (zh) * | 2019-05-30 | 2019-09-17 | 成都吉诺迈尔生物科技有限公司 | 一种表征hHRD同源重组缺陷的基因组重组指纹及其鉴定方法 |
| CN110527744A (zh) * | 2019-05-30 | 2019-12-03 | 四川大学华西第二医院 | 一组与同源重组修复缺陷相关的基因组特征性突变指纹的鉴定方法 |
| US11648211B2 (en) * | 2019-09-23 | 2023-05-16 | Northeastern University | Nanoencapsulated combination drug formulations |
| WO2021249996A1 (en) * | 2020-06-08 | 2021-12-16 | Oncology Venture ApS | Compositions comprising 2x-121 and methods for treating coronavirus infection |
| IL300229A (en) * | 2020-07-31 | 2023-03-01 | Univ Alberta | Using beta-catenin/WNT pathway inhibitors to block replication of SARS-COV-2 and other pathogenic viruses |
-
2021
- 2021-02-24 US US17/801,729 patent/US20240016775A1/en active Pending
- 2021-02-24 WO PCT/CN2021/077610 patent/WO2021169984A1/zh not_active Ceased
- 2021-02-24 CA CA3169303A patent/CA3169303A1/en active Pending
- 2021-02-24 EP EP21761835.4A patent/EP4112049A4/en active Pending
- 2021-02-24 JP JP2022576572A patent/JP7881489B2/ja active Active
- 2021-02-24 CN CN202110218734.7A patent/CN113288892B/zh active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP7516338B2 (ja) | 抗菌化合物 | |
| CN106103416B (zh) | 作为trpm8拮抗剂的氮杂螺衍生物 | |
| KR102030305B1 (ko) | 키나제 억제제로서 유용한 인돌 카르복스아미드 화합물 | |
| RU2497813C2 (ru) | 4-(4-циано-2-тиоарил)-дигидропиримидиноны и их применение | |
| TW202200552A (zh) | 作為用於免疫活化之DGKζ抑制劑之經取代胺基噻唑 | |
| ES2884067T3 (es) | Derivados de indolina sustituidos como inhibidores de la replicación viral del dengue | |
| JP2021530478A5 (enExample) | ||
| KR20150074122A (ko) | 전압-게이팅 나트륨 채널에서 선택적 활성을 갖는 벤족사졸리논 화합물 | |
| TW201722933A (zh) | 苯內醯胺化合物 | |
| KR102514914B1 (ko) | 카르바졸 유도체 | |
| EP3958865B1 (en) | 4h-pyrrolo[3,2-c]pyridin-4-one derivatives | |
| JP2012503018A5 (enExample) | ||
| RU2007120454A (ru) | Производные хинуклидина и их применение в качестве антагонистов мускариновых рецепторов м3 | |
| CA2392584A1 (en) | Substituted pyridazines having cytokine inhibitory activity | |
| TW201713619A (zh) | 醯胺基取代之環己烷衍生物 | |
| JP2018512381A5 (enExample) | ||
| HUP0400718A2 (hu) | PDE7 és PDE4 kettős inhibitorok alkalmazása leukocita aktivitással társult betegségek kezelésére szolgáló gyógyszerkészítmények előállítására | |
| JP2005510473A5 (enExample) | ||
| CN108892661A (zh) | 治疗化合物和组合物 | |
| EP3209664A1 (en) | Bicyclic heteroaryl amine compounds as pi3k inhibitors | |
| JP2025503996A5 (enExample) | ||
| WO2017152062A1 (en) | Compositions and combinations of autotaxin inhibitors | |
| JP2023522177A5 (enExample) | ||
| RU2664533C2 (ru) | Геминально-замещенные цианоэтилпиразолопиридоны в качестве ингибиторов janus киназ | |
| JP2024521818A5 (enExample) |