HUP0400718A2 - PDE7 és PDE4 kettős inhibitorok alkalmazása leukocita aktivitással társult betegségek kezelésére szolgáló gyógyszerkészítmények előállítására - Google Patents

PDE7 és PDE4 kettős inhibitorok alkalmazása leukocita aktivitással társult betegségek kezelésére szolgáló gyógyszerkészítmények előállítására

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Publication number
HUP0400718A2
HUP0400718A2 HU0400718A HUP0400718A HUP0400718A2 HU P0400718 A2 HUP0400718 A2 HU P0400718A2 HU 0400718 A HU0400718 A HU 0400718A HU P0400718 A HUP0400718 A HU P0400718A HU P0400718 A2 HUP0400718 A2 HU P0400718A2
Authority
HU
Hungary
Prior art keywords
pde
preparation
leukocyte activation
pharmaceutical compositions
associated disorders
Prior art date
Application number
HU0400718A
Other languages
English (en)
Inventor
John H. Dodd
William John Pitts
Andrew J. Watson
Original Assignee
Bristol-Myers Squibb Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol-Myers Squibb Co. filed Critical Bristol-Myers Squibb Co.
Publication of HUP0400718A2 publication Critical patent/HUP0400718A2/hu

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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
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Abstract

A találmány tárgyát kettős PDE7 és PDE4 inhibitorok alkalmazása képezileukocita aktiválással társult rendellenességek, különösentranszplantátum-kilökődés, reumatoid artritisz, gyulladásosbélbetegség, pszoriázis, asztma, krónikus elzáródásos tüdőbetegség,bőrfarkas és szklerózis multiplex kezelésére szolgálógyógyszerkészítmények előállítására. Ó
HU0400718A 2001-05-01 2002-04-30 PDE7 és PDE4 kettős inhibitorok alkalmazása leukocita aktivitással társult betegségek kezelésére szolgáló gyógyszerkészítmények előállítására HUP0400718A2 (hu)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US28796401P 2001-05-01 2001-05-01
US29928701P 2001-06-19 2001-06-19
US36875202P 2002-03-29 2002-03-29
PCT/US2002/013742 WO2002088080A2 (en) 2001-05-01 2002-04-30 Dual inhibitors of pde 7 and pde 4

Publications (1)

Publication Number Publication Date
HUP0400718A2 true HUP0400718A2 (hu) 2004-07-28

Family

ID=27403765

Family Applications (2)

Application Number Title Priority Date Filing Date
HU0400718A HUP0400718A2 (hu) 2001-05-01 2002-04-30 PDE7 és PDE4 kettős inhibitorok alkalmazása leukocita aktivitással társult betegségek kezelésére szolgáló gyógyszerkészítmények előállítására
HU0400828A HUP0400828A2 (hu) 2001-05-01 2002-05-01 Kondenzált heterociklikus aminopirimidinek, alkalmazásuk és az ezeket tartalmazó gyógyszerkészítmények

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU0400828A HUP0400828A2 (hu) 2001-05-01 2002-05-01 Kondenzált heterociklikus aminopirimidinek, alkalmazásuk és az ezeket tartalmazó gyógyszerkészítmények

Country Status (6)

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US (2) US20030104974A1 (hu)
EP (2) EP1383743A4 (hu)
JP (2) JP2004532233A (hu)
CA (2) CA2444436A1 (hu)
HU (2) HUP0400718A2 (hu)
WO (3) WO2002088079A2 (hu)

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JP2006219374A (ja) 2003-06-13 2006-08-24 Daiichi Asubio Pharma Co Ltd Ｐｄｅ７阻害作用を有するイミダゾトリアジノン誘導体
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