|
US5266488A
(en)
|
1988-04-06 |
1993-11-30 |
The Regents Of The University Of California |
Troponin T gene promoter and derivatives thereof
|
|
WO2001029062A2
(en)
|
1999-10-18 |
2001-04-26 |
University Technology Corporation |
Method for modulation of cell phenotype
|
|
WO2002081632A2
(en)
|
2001-04-04 |
2002-10-17 |
The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services |
Nucleic acids for transgene expression
|
|
CN1880457B
(zh)
*
|
2001-10-11 |
2010-05-26 |
麦克公司 |
Ad6重组核酸
|
|
US20030221207A1
(en)
|
2002-02-13 |
2003-11-27 |
Pharmacia Corporation, Global Patent Department |
Cardiac-specific 11beta hydroxysteroid dehydrogenase type 2 transgenic mice
|
|
US9441244B2
(en)
|
2003-06-30 |
2016-09-13 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
|
CN101056539B
(zh)
|
2004-09-09 |
2012-12-12 |
综合医院公司 |
调节心脏细胞中的磷酸酶活性
|
|
JP5136766B2
(ja)
|
2004-12-15 |
2013-02-06 |
ユニバーシティ オブ ノース カロライナ アット チャペル ヒル |
キメラベクター
|
|
US9018440B2
(en)
|
2006-10-27 |
2015-04-28 |
Stowers Institute For Medical Research |
Fluorescent mouse model
|
|
US20100261169A1
(en)
|
2007-01-29 |
2010-10-14 |
Shira Wallach |
Novel nucleotide and amino acid sequences, and methods of use thereof for diagnosis
|
|
ES2714007T3
(es)
|
2007-04-09 |
2019-05-24 |
Univ Florida |
Composiciones de vectores rAAV que tienen proteínas de la cápside modificadas en tirosina y métodos para su uso
|
|
US9725485B2
(en)
|
2012-05-15 |
2017-08-08 |
University Of Florida Research Foundation, Inc. |
AAV vectors with high transduction efficiency and uses thereof for gene therapy
|
|
US20090133138A1
(en)
*
|
2007-11-15 |
2009-05-21 |
Huai-Jen Tsai |
New gene fragment, novel transgenic zebrafish and methods for producing transgenic zebrafish
|
|
WO2009065080A1
(en)
|
2007-11-16 |
2009-05-22 |
San Diego State University Research Foundation |
Compositions and method for manipulating pim-1 activity in circulatory system cells
|
|
WO2009137006A2
(en)
|
2008-04-30 |
2009-11-12 |
The University Of North Carolina At Chapel Hill |
Directed evolution and in vivo panning of virus vectors
|
|
US9217155B2
(en)
|
2008-05-28 |
2015-12-22 |
University Of Massachusetts |
Isolation of novel AAV'S and uses thereof
|
|
US20110158947A1
(en)
|
2008-07-11 |
2011-06-30 |
Aleksandar Jovanovic |
Sulfonylurea receptor and means for treating ischaemia
|
|
US20110165680A1
(en)
|
2008-09-12 |
2011-07-07 |
Scarab Genomics, Llc |
Clean genome bactofection
|
|
WO2010093784A2
(en)
|
2009-02-11 |
2010-08-19 |
The University Of North Carolina At Chapel Hill |
Modified virus vectors and methods of making and using the same
|
|
US8734809B2
(en)
|
2009-05-28 |
2014-05-27 |
University Of Massachusetts |
AAV's and uses thereof
|
|
CN103608455B
(zh)
*
|
2011-01-07 |
2019-01-15 |
应用遗传科技公司 |
用于治疗色盲和其它疾病的启动子、表达盒、载体、药盒和方法
|
|
DE102011018586A1
(de)
|
2011-04-26 |
2012-10-31 |
Oliver Müller |
Vektorsystem zur spezifischen Genexpression im Herzmuskel
|
|
EP2714709B1
(en)
|
2011-05-26 |
2018-04-18 |
University of Washington |
Compositions for use in cell and gene based methods to improve cardiac function
|
|
JP2014520551A
(ja)
|
2011-07-11 |
2014-08-25 |
セルラー ダイナミクス インターナショナル， インコーポレイテッド |
細胞のリプログラミング方法およびゲノムの改変方法
|
|
CN111500665A
(zh)
|
2011-07-21 |
2020-08-07 |
小利兰·斯坦福大学托管委员会 |
来自患者的诱导性多能干细胞的心肌细胞及其使用方法
|
|
US8933048B2
(en)
|
2011-09-21 |
2015-01-13 |
Case Western Reserve University |
Methods of treating cardiomyopathy
|
|
US20130136729A1
(en)
|
2011-11-11 |
2013-05-30 |
University of Virginia Patent Foundation, d/b/a University of Virginia Licensing & Ventures Group |
Compositions and methods for targeting and treating diseases and injuries using adeno-associated virus vectors
|
|
US9051387B2
(en)
|
2012-06-22 |
2015-06-09 |
Wisconsin Alumni Research Foundation |
Inhibition of MyBP-C binding to myosin as a treatment for heart failure
|
|
US9845465B2
(en)
*
|
2012-08-15 |
2017-12-19 |
University Of Virginia Patent Foundation |
Compositions and methods for treating peripheral arterial disease
|
|
EP2792742A1
(en)
|
2013-04-17 |
2014-10-22 |
Universitätsklinikum Hamburg-Eppendorf (UKE) |
Gene-therapy vectors for treating cardiomyopathy
|
|
US20160237430A1
(en)
|
2013-09-23 |
2016-08-18 |
President And Fellows Of Harvard College |
Allele-specific rna silencing for the treatment of hypertrophic cardiomyopathy
|
|
JP6707028B2
(ja)
|
2013-12-09 |
2020-06-10 |
ベイラー カレッジ オブ メディスンＢａｙｌｏｒ Ｃｏｌｌｅｇｅ Ｏｆ Ｍｅｄｉｃｉｎｅ |
心筋細胞新生におけるｈｉｐｐｏ及びジストロフィン複合体シグナル伝達
|
|
DE102014000857A1
(de)
|
2014-01-27 |
2015-07-30 |
Martin-Luther-Universität Halle-Wittenberg |
Hybridom-Zelllinie (My-C-cC0C2-235-3H8) und deren Verwendung zur Herstellung eines monoklonalen Antikörpers gegen das humane, herzspezifische Myosin Binding Protein C (C-protein, MYBPC3, cMyBP-C oder My-C)
|
|
US10072251B2
(en)
|
2014-02-19 |
2018-09-11 |
University Of Massachusetts |
Recombinant AAVS having useful transcytosis properties
|
|
WO2015124546A1
(en)
|
2014-02-19 |
2015-08-27 |
Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii- Cnic |
Aav vectors for the treatment of ischemic and non-ischemic heart disease
|
|
WO2015153357A1
(en)
|
2014-03-29 |
2015-10-08 |
Beat Biotherapeutics Corp. |
Compositions and methods for improving cardiac function
|
|
US9611304B2
(en)
|
2014-05-29 |
2017-04-04 |
The University Of British Columbia |
TNNT1 mini-promoters
|
|
US10370432B2
(en)
|
2014-10-03 |
2019-08-06 |
University Of Massachusetts |
Heterologous targeting peptide grafted AAVS
|
|
CN107073051B
(zh)
|
2014-10-21 |
2021-08-24 |
马萨诸塞大学 |
重组aav变体及其用途
|
|
JP6832280B2
(ja)
|
2015-01-16 |
2021-02-24 |
ユニバーシティ オブ ワシントンＵｎｉｖｅｒｓｉｔｙ ｏｆ Ｗａｓｈｉｎｇｔｏｎ |
新規のマイクロジストロフィンおよび使用の関連する方法
|
|
JP6836999B2
(ja)
|
2015-03-24 |
2021-03-03 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアＴｈｅ Ｒｅｇｅｎｔｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃａｌｉｆｏｒｎｉａ |
アデノ随伴ウイルス変異体及びその使用方法
|
|
EP3283126B1
(en)
|
2015-04-16 |
2019-11-06 |
Emory University |
Recombinant promoters and vectors for protein expression in liver and use thereof
|
|
WO2017091807A1
(en)
|
2015-11-25 |
2017-06-01 |
University Of Miami |
Peptide inhibitors for calcineurin
|
|
KR102423442B1
(ko)
|
2015-12-11 |
2022-07-20 |
캘리포니아 인스티튜트 오브 테크놀로지 |
아데노-관련 바이러스를 지시하기 위한 타겟팅 펩타이드
|
|
JP7406783B2
(ja)
|
2015-12-14 |
2023-12-28 |
ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル |
パルボウイルスベクターの高められた送達のための改変キャプシドタンパク質
|
|
MX2018007330A
(es)
*
|
2015-12-15 |
2019-03-14 |
Genzyme Corp |
Vectores virales adeno-asociados para tratar mucolipidosis de tipo ii.
|
|
US11866462B2
(en)
|
2016-05-04 |
2024-01-09 |
Oregon Health & Science University |
Recombinant adeno-associated viral vectors
|
|
WO2017212019A1
(en)
|
2016-06-09 |
2017-12-14 |
Centre National De La Recherche Scientifique (Cnrs) |
Raav with chemically modified capsid
|
|
WO2018050783A1
(en)
|
2016-09-14 |
2018-03-22 |
Ruprecht-Karls-Universität |
Adeno-associated virus (aav) based regulatory system
|
|
WO2018067701A2
(en)
|
2016-10-05 |
2018-04-12 |
The Regents Of The University Of California |
Cardiac tissue models and methods of use thereof
|
|
CN108384806A
(zh)
|
2016-10-17 |
2018-08-10 |
新疆医科大学第附属医院 |
hPDGF-BB与hFGF2双基因重组病毒载体及其应用
|
|
EP3534930A1
(en)
|
2016-11-04 |
2019-09-11 |
Ruprecht-Karls-Universität Heidelberg |
Wnt antagonists and their use in methods for treating myocardial infarction
|
|
JOP20190166A1
(ar)
*
|
2017-01-05 |
2019-07-02 |
Univ Texas |
استراتيجية مثلى من أجل تعديلات تخطي إكسون باستخدام crispr/cas9 مع متواليات توجيه ثلاثي
|
|
US11905312B2
(en)
|
2017-02-15 |
2024-02-20 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for gene transfer across the vasculature
|
|
US10550405B2
(en)
|
2017-03-15 |
2020-02-04 |
The University Of North Carolina At Chapel Hill |
Rational polyploid adeno-associated virus vectors and methods of making and using the same
|
|
WO2018222503A1
(en)
|
2017-05-31 |
2018-12-06 |
The Regents Of The University Of California |
Adeno-associated virus with variant capsid and methods of use thereof
|
|
EP3658157B1
(en)
|
2017-07-06 |
2023-07-26 |
Michael S. Kapiloff |
Treatment of heart disease by inhibition of the action of muscle a-kinase anchoring protein (makap)
|
|
EP3808849A1
(en)
|
2017-08-03 |
2021-04-21 |
Voyager Therapeutics, Inc. |
Compositions and methods for delivery of aav
|
|
ES2976559T3
(es)
|
2017-09-20 |
2024-08-05 |
Univ California |
Terapia génica con conexina 43 para restaurar la función eléctrica y cardíaca y la estructura cardíaca, en la miocardiopatía arritmogénica del ventrículo derecho
|
|
RU2770922C2
(ru)
|
2017-09-20 |
2022-04-25 |
4Д Молекьюлар Терапьютикс Инк. |
Капсиды вариантов аденоассоциированных вирусов и методы их применения
|
|
CN111886029B
(zh)
|
2018-01-19 |
2024-04-12 |
新加坡科技研究局 |
破坏linc复合物以治疗核纤层蛋白病
|
|
GB2571704A
(en)
|
2018-02-22 |
2019-09-11 |
Georg August Univ Gottingen Stiftung Offentlichen Rechts Univer Sitatsmedzin Goettingen |
Prevention or treatment of cardiac arrhytmia and sudden cardiac death
|
|
CN112153990A
(zh)
*
|
2018-03-23 |
2020-12-29 |
纽约市哥伦比亚大学理事会 |
用于常染色体显性疾病的基因编辑
|
|
WO2020014471A1
(en)
|
2018-07-11 |
2020-01-16 |
The Brigham And Women's Hospital, Inc. |
Methods and compositions for delivery of agents across the blood-brain barrier
|
|
US11242368B2
(en)
|
2018-09-21 |
2022-02-08 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Methods and compositions for rapidly replacing cardiac myosin binding protein-C in sarcomeres
|
|
KR20220022107A
(ko)
|
2018-12-05 |
2022-02-24 |
아베오나 테라퓨틱스 인코퍼레이티드 |
유전자 전달을 위한 재조합 아데노-연관 바이러스 벡터
|
|
CN109810981A
(zh)
|
2019-02-19 |
2019-05-28 |
上海交通大学医学院附属第九人民医院 |
多聚核苷酸及其在心血管疾病诊断和治疗中的应用
|
|
AR118465A1
(es)
|
2019-03-21 |
2021-10-06 |
Stridebio Inc |
Vectores de virus adenoasociados recombinantes
|
|
KR102934700B1
(ko)
|
2019-03-28 |
2026-03-09 |
더 제너럴 하스피탈 코포레이션 |
트랜스진 발현을 위한 조작된 아데노-연관 (aav) 벡터
|
|
US20200405824A1
(en)
|
2019-06-26 |
2020-12-31 |
University Of Washington |
Use of ribonucleotide reductase alone or in combination with micro-dystrophin to treat duchenne muscular dystrophy striated muscle disease
|
|
EP4021527B1
(en)
|
2019-08-27 |
2024-03-06 |
Dinaqor AG |
Drug perfusion into an unarrested beating heart
|
|
TWI897882B
(zh)
|
2019-09-20 |
2025-09-21 |
英商Ｕｃｌ商業有限責任公司 |
右心室心律失常性心肌病之基因療法組合物及治療
|
|
EP4073257A1
(en)
|
2019-12-09 |
2022-10-19 |
UCL Business Ltd |
Gene therapy composition and treatment for myh7-linked cardiomyopathy
|
|
EP4081643A1
(en)
|
2019-12-24 |
2022-11-02 |
Asklepios Biopharmaceutical, Inc. |
Regulatory nucleic acid sequences
|
|
EP4103214B1
(en)
|
2020-02-13 |
2026-04-29 |
Tenaya Therapeutics, Inc. |
Gene therapy vectors for treating heart disease
|
|
WO2021163357A2
(en)
|
2020-02-13 |
2021-08-19 |
Tenaya Therapeutics, Inc. |
Gene therapy vectors for treating heart disease
|
|
US12552838B2
(en)
|
2020-04-20 |
2026-02-17 |
Tenaya Therapeutics, Inc. |
Adeno-associated virus with engineered capsid
|
|
CA3186584A1
(en)
|
2020-07-08 |
2022-01-13 |
Children's Medical Center Corporation |
Mybpc3 polypeptides and uses thereof
|
|
KR20230042468A
(ko)
|
2020-08-05 |
2023-03-28 |
스페이스크래프트 세븐, 엘엘씨 |
Csrp3 (시스테인 및 글리신 풍부 단백질 3) 유전자 요법
|
|
KR20230043869A
(ko)
|
2020-08-07 |
2023-03-31 |
스페이스크래프트 세븐, 엘엘씨 |
Aav 벡터를 사용한 플라코필린-2(pkp2) 유전자 요법
|
|
JP2024501821A
(ja)
|
2020-12-23 |
2024-01-16 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
心臓組織細胞に対する特異性を有するウイルスカプシドタンパク質
|
|
EP4294494A1
(en)
|
2021-02-22 |
2023-12-27 |
Dinaqor AG |
Loco-regional perfusion of a liver
|
|
MX2023009819A
(es)
|
2021-02-22 |
2024-01-03 |
Dinaqor Ag |
Perfusion loco-regional de un ri?on.
|
|
KR20230173088A
(ko)
|
2021-02-22 |
2023-12-26 |
디나코 아게 |
정지되지 않은 박동 심장의 국소-영역 관류
|