JP2023052910A5 - - Google Patents
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- JP2023052910A5 JP2023052910A5 JP2023015725A JP2023015725A JP2023052910A5 JP 2023052910 A5 JP2023052910 A5 JP 2023052910A5 JP 2023015725 A JP2023015725 A JP 2023015725A JP 2023015725 A JP2023015725 A JP 2023015725A JP 2023052910 A5 JP2023052910 A5 JP 2023052910A5
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2025113314A JP7754361B2 (ja) | 2017-04-28 | 2025-07-03 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
| JP2025166056A JP2025185050A (ja) | 2017-04-28 | 2025-10-02 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017090679 | 2017-04-28 | ||
| JP2017090679 | 2017-04-28 | ||
| PCT/JP2018/017345 WO2018199337A1 (ja) | 2017-04-28 | 2018-04-27 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
| JP2019514691A JP7222347B2 (ja) | 2017-04-28 | 2018-04-27 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019514691A Division JP7222347B2 (ja) | 2017-04-28 | 2018-04-27 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025113314A Division JP7754361B2 (ja) | 2017-04-28 | 2025-07-03 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2023052910A JP2023052910A (ja) | 2023-04-12 |
| JP2023052910A5 true JP2023052910A5 (enExample) | 2023-04-25 |
| JP7708133B2 JP7708133B2 (ja) | 2025-07-15 |
Family
ID=63918939
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019514691A Active JP7222347B2 (ja) | 2017-04-28 | 2018-04-27 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
| JP2023015725A Active JP7708133B2 (ja) | 2017-04-28 | 2023-02-03 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
| JP2025113314A Active JP7754361B2 (ja) | 2017-04-28 | 2025-07-03 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
| JP2025166056A Pending JP2025185050A (ja) | 2017-04-28 | 2025-10-02 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019514691A Active JP7222347B2 (ja) | 2017-04-28 | 2018-04-27 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2025113314A Active JP7754361B2 (ja) | 2017-04-28 | 2025-07-03 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
| JP2025166056A Pending JP2025185050A (ja) | 2017-04-28 | 2025-10-02 | 可溶性タンパク質に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US12024549B2 (enExample) |
| EP (2) | EP4603507A3 (enExample) |
| JP (4) | JP7222347B2 (enExample) |
| KR (3) | KR20240046307A (enExample) |
| CN (1) | CN110637036A (enExample) |
| AU (2) | AU2018259856B2 (enExample) |
| CA (1) | CA3061467A1 (enExample) |
| WO (1) | WO2018199337A1 (enExample) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7291395B2 (ja) * | 2017-06-16 | 2023-06-15 | 国立大学法人 鹿児島大学 | IgG結合ペプチド、及び該ペプチドによる抗体の特異的修飾 |
| EP3808760A4 (en) * | 2018-06-14 | 2022-10-05 | Ajinomoto Co., Inc. | COMPOUND WITH AFFINITY FOR ANTIBODY, CLEAVAGE SITE AND REACTIVE GROUP OR SALT THEREOF |
| JPWO2019240288A1 (ja) * | 2018-06-14 | 2021-07-26 | 味の素株式会社 | 抗体に対する親和性物質、および生体直交性官能基を有する化合物またはその塩 |
| JPWO2020090979A1 (ja) * | 2018-10-31 | 2021-09-24 | 味の素株式会社 | 抗体に対する親和性物質、切断性部分および反応性基を有する化合物またはその塩 |
| CN113631539B (zh) * | 2019-01-23 | 2025-08-15 | 阿比蒂斯有限公司 | 用于制备抗体-载荷部分偶联物的化合物及其用途 |
| WO2020184944A1 (ko) * | 2019-03-08 | 2020-09-17 | 앱티스 주식회사 | 위치특이적 항체 콘쥬게이션 및 이의 구체예로서의 항체-약물 콘쥬게이트 |
| CA3155284A1 (en) | 2019-10-24 | 2021-04-29 | Yuji Ito | Method for producing monovalent ccap product |
| AU2020388383A1 (en) * | 2019-11-18 | 2022-03-31 | Kleo Pharmaceuticals, Inc. | Directed conjugation technologies |
| US20230046947A1 (en) * | 2019-12-03 | 2023-02-16 | Debiopharm Research & Manufacturing S.A. | Reactive conjugates |
| WO2022078566A1 (en) * | 2020-10-12 | 2022-04-21 | Debiopharm Research & Manufacturing S.A. | Reactive conjugates |
| CA3208290A1 (en) | 2021-01-18 | 2022-07-21 | Ajinomoto Co., Inc. | Compound or salt thereof, and antibody obtained by using the same |
| CN116829573A (zh) * | 2021-01-18 | 2023-09-29 | 味之素株式会社 | 化合物或其盐、及由它们得到的抗体 |
| WO2022191283A1 (ja) | 2021-03-11 | 2022-09-15 | 味の素株式会社 | 化合物またはその塩、およびそれらにより得られる抗体 |
| JPWO2022196675A1 (enExample) | 2021-03-16 | 2022-09-22 | ||
| CN113292633B (zh) * | 2021-05-13 | 2023-08-29 | 中国科学技术大学 | 可见光诱导甘氨酸衍生物的肼化修饰方法 |
| KR20240012380A (ko) * | 2021-05-17 | 2024-01-29 | 바이오하벤 테라퓨틱스 리미티드 | 지향 접합 기술용 제제 및 접합 생성물 |
| JP2024521092A (ja) * | 2021-05-19 | 2024-05-28 | バイオヘイブン・セラピューティクス・リミテッド | 細胞傷害性薬剤を送達するためのmates技術を使用する抗体薬物コンジュゲート |
| EP4349373A1 (en) | 2021-06-01 | 2024-04-10 | Ajinomoto Co., Inc. | Conjugate of antibody and functional substance or salt of said conjugate, and compound for use in production of said conjugate or salt of said compound |
| CA3224147A1 (en) | 2021-07-09 | 2023-01-12 | Vijaya Raghavan PATTABIRAMAN | Antibody conjugates and manufacture thereof |
| WO2023281479A1 (en) | 2021-07-09 | 2023-01-12 | Bright Peak Therapeutics Ag | Checkpoint inhibitors conjugated to il-2, and uses thereof |
| WO2023281483A1 (en) | 2021-07-09 | 2023-01-12 | Bright Peak Therapeutics Ag | Modified tnf-antibodies and uses thereof |
| US20230201365A1 (en) | 2021-07-09 | 2023-06-29 | Bright Peak Therapeutics Ag | Modified cd20 antibodies and uses thereof |
| JP2024529297A (ja) | 2021-07-09 | 2024-08-06 | ブライト ピーク セラピューティクス エージー | Il-2を有するチェックポイント阻害剤のコンジュゲート及びその使用 |
| CA3231257A1 (en) | 2021-09-08 | 2023-03-16 | Yuji Ito | Compound, salt of compound, antibody modification reagent, method for producing modified antibody, and modified antibody |
| WO2023054714A1 (ja) | 2021-09-30 | 2023-04-06 | 味の素株式会社 | 抗体および機能性物質の位置選択的なコンジュゲートまたはその塩、ならびにその製造に用いられる抗体誘導体および化合物またはそれらの塩 |
| KR20240073035A (ko) | 2021-09-30 | 2024-05-24 | 아지노모토 가부시키가이샤 | 항체 및 기능성 물질의 컨쥬게이트 또는 그 염, 및 그 제조에 사용되는 항체 유도체 및 화합물 또는 그 염 |
| EP4482531A1 (en) | 2022-02-23 | 2025-01-01 | Bright Peak Therapeutics AG | Immune antigen specific il-18 immunocytokines and uses thereof |
| US20250163101A1 (en) | 2022-03-04 | 2025-05-22 | AbTis Co., Ltd. | Method for increasing production yield of antibody-drug conjugate by using thiol-reactive additive |
| CN116836235A (zh) * | 2022-03-25 | 2023-10-03 | 中国科学院上海药物研究所 | 亲和片段导向的可裂解片段,其设计、合成及在制备定点药物偶联物中的应用 |
| JPWO2023234416A1 (enExample) * | 2022-06-02 | 2023-12-07 | ||
| KR20240125071A (ko) | 2022-11-01 | 2024-08-19 | 앱티스 주식회사 | Fc 결합성 유닛을 포함하는 화합물 및 이를 이용하여 제조된 컨쥬게이트 |
| US20240417436A1 (en) | 2023-01-11 | 2024-12-19 | Bright Peak Therapeutics Ag | Conditionally activated immunocytokines and methods of use |
| US20240424127A1 (en) | 2023-01-11 | 2024-12-26 | Bright Peak Therapeutics Ag | Il-7 polypeptides, immunocytokines comprising same, and uses thereof |
| EP4682173A1 (en) * | 2023-03-15 | 2026-01-21 | Kagoshima University | Method for producing radiolabeled antibody, radiolabeled antibody, and radioactive medicine |
| KR20250172615A (ko) | 2023-04-04 | 2025-12-09 | 아지노모토 가부시키가이샤 | 항체 및 기능성 물질의 컨쥬게이트, 항체 유도체 및 화합물, 또는 그것들의 염 |
| JPWO2024210178A1 (enExample) | 2023-04-05 | 2024-10-10 | ||
| US20250188166A1 (en) | 2023-08-23 | 2025-06-12 | Bright Peak Therapeutics Ag | Il-18 polypeptides fused to immune cell antigen specific binding polypeptides and uses thereof |
| WO2025041101A1 (en) | 2023-08-23 | 2025-02-27 | Bright Peak Therapeutics Ag | Activatable il-18 immunocytokines and uses thereof |
| WO2025041102A1 (en) | 2023-08-23 | 2025-02-27 | Bright Peak Therapeutics Ag | Targeted immune activation with il-18 immunocytokines |
| WO2025076127A1 (en) | 2023-10-05 | 2025-04-10 | Capstan Therapeutics, Inc. | Constrained ionizable cationic lipids and lipid nanoparticles |
| WO2025076113A1 (en) | 2023-10-05 | 2025-04-10 | Capstan Therapeutics, Inc. | Ionizable cationic lipids with conserved spacing and lipid nanoparticles |
| US20250144234A1 (en) | 2023-11-02 | 2025-05-08 | Capstan Therapeutics Inc. | RNA for In vivo Transfection with Increased Expression |
| US20250332281A2 (en) | 2023-12-15 | 2025-10-30 | Capstan Therapeutics, Inc. | Humanized anti-cd8 antibodies and uses thereof |
| WO2025158412A1 (en) | 2024-01-26 | 2025-07-31 | Biohaven Therapeutics Ltd. | BIFUNCTIONAL DEGRADERS OF IgG4 IMMUNOGLOBULINS |
| US20250302763A1 (en) | 2024-02-22 | 2025-10-02 | Capstan Therapeutics, Inc. | Immune engineering amplification |
| WO2025181697A1 (en) | 2024-02-26 | 2025-09-04 | Biohaven Therapeutics Ltd. | Bifunctional degraders of anti-pla2r antibody |
| WO2025210538A1 (en) | 2024-04-02 | 2025-10-09 | Biohaven Therapeutics Ltd. | Bifunctional degraders |
| WO2025217452A1 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Constrained ionizable cationic lipids and lipid nanoparticles |
| WO2025217454A2 (en) | 2024-04-11 | 2025-10-16 | Capstan Therapeutics, Inc. | Ionizable cationic lipids and lipid nanoparticles |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL89220A (en) | 1988-02-11 | 1994-02-27 | Bristol Myers Squibb Co | Anthracycline immunoconjugates, their production and pharmaceutical compositions containing them |
| US5622929A (en) | 1992-01-23 | 1997-04-22 | Bristol-Myers Squibb Company | Thioether conjugates |
| US6214345B1 (en) | 1993-05-14 | 2001-04-10 | Bristol-Myers Squibb Co. | Lysosomal enzyme-cleavable antitumor drug conjugates |
| JP2000503639A (ja) | 1995-12-22 | 2000-03-28 | ブリストル―マイヤーズ スクイブ カンパニー | 分枝ヒドラゾンのリンカー類 |
| JP3825502B2 (ja) * | 1996-06-11 | 2006-09-27 | 日本油脂株式会社 | 修飾蛋白質の製造法及びコンタクトレンズ用汚れ除去剤 |
| ATE218892T1 (de) * | 1997-11-07 | 2002-06-15 | Conjuchem Inc | Affinitätsmarkierer für menschliches serum albumin |
| EP1757311B1 (en) | 1999-12-24 | 2009-02-11 | Genentech, Inc. | Methods and compositions for prolonging elimination half-times of bioactive compounds |
| DE60030323T2 (de) | 1999-12-24 | 2007-10-11 | Genentech, Inc., South San Francisco | Verfahren und verbindungen zur verlängerung der halbwertzeiten bei der ausscheidung von biowirksamen verbindungen |
| EP1243276A1 (en) | 2001-03-23 | 2002-09-25 | Franciscus Marinus Hendrikus De Groot | Elongated and multiple spacers containing activatible prodrugs |
| DE10162773A1 (de) | 2001-12-20 | 2003-07-10 | Knf Flodos Ag Sursee | Dosierpumpe |
| CA2802205C (en) | 2002-07-31 | 2016-01-19 | Seattle Genetics, Inc. | Drug conjugates and their use for treating cancer, an autoimmune disease or an infectious disease |
| EP1560599A1 (en) | 2002-11-14 | 2005-08-10 | Syntarga B.V. | Prodrugs built as multiple self-elimination-release spacers |
| CN103394083B (zh) | 2003-11-06 | 2017-07-18 | 西雅图基因公司 | 能够与配体偶联的单甲基缬氨酸化合物 |
| NZ550934A (en) | 2004-05-19 | 2010-05-28 | Medarex Inc | Chemical linkers and conjugates thereof |
| JP5167473B2 (ja) | 2005-03-03 | 2013-03-21 | コヴェックス・テクノロジーズ・アイルランド・リミテッド | 抗血管新生化合物 |
| US8637656B2 (en) | 2005-07-05 | 2014-01-28 | Ribomic Inc. | Nucleic acid capable of binding to immunoglobulin G and use thereof |
| EP1989547A1 (en) | 2006-02-28 | 2008-11-12 | Medical Research Council | Targeted iron oxide nanoparticles |
| EP2093287A4 (en) | 2006-11-02 | 2010-04-21 | Univ Kagoshima | PEPTIDE BINDER IGG |
| WO2008056346A2 (en) | 2006-11-10 | 2008-05-15 | Covx Technologies Ireland Limited | Anti-angiogenic compounds |
| WO2011121560A2 (en) * | 2010-03-31 | 2011-10-06 | Universite De Geneve | Stabilized antibody preparations and uses thereof |
| CN103890174B (zh) | 2011-08-24 | 2015-12-23 | 大塚化学株式会社 | IgG结合性肽及利用其检测和纯化IgG的方法 |
| DK2863955T3 (en) | 2012-06-26 | 2017-01-23 | Sutro Biopharma Inc | MODIFIED FC PROTEINS, INCLUDING LOCATION-SPECIFIC NON-NATURAL AMINO ACID RESIDUES, CONJUGATES THEREOF, METHODS OF PRODUCING ITS AND PROCEDURES FOR USE THEREOF |
| CA2916202C (en) * | 2013-06-24 | 2019-07-02 | Hanwha Chemical Corporation | Antibody-drug conjugate having improved stability and use thereof |
| CN113332449B (zh) * | 2014-06-12 | 2023-12-22 | 石药集团巨石生物制药有限公司 | 酶法制备同质的抗体-药物缀合物 |
| US20160000933A1 (en) * | 2014-07-01 | 2016-01-07 | Andrei POLUKHTIN | Conjugated biological molecules and their preparation |
| JP5827769B1 (ja) | 2015-03-27 | 2015-12-02 | 義徳 川窪 | 掃除装置 |
| US10227383B2 (en) * | 2015-05-20 | 2019-03-12 | Kagoshima University | Specific modification of antibody with IgG-binding peptide |
| TWI703158B (zh) * | 2015-09-18 | 2020-09-01 | 美商希佛隆公司 | 特異性結合tl1a之抗體 |
| BR112018012388A2 (pt) | 2015-12-18 | 2018-12-04 | Eisai R&D Management Co., Ltd. | imunoglobulinas conjugadas de lisina terminal-c |
| JP7020403B2 (ja) * | 2016-05-02 | 2022-02-16 | 味の素株式会社 | アジド基含有Fcタンパク質 |
| CN109071606A (zh) * | 2016-06-13 | 2018-12-21 | 国立大学法人鹿儿岛大学 | 利用IgG结合肽的位点特异性放射性同位素标记抗体 |
-
2018
- 2018-04-27 CN CN201880027775.4A patent/CN110637036A/zh active Pending
- 2018-04-27 KR KR1020247010619A patent/KR20240046307A/ko active Pending
- 2018-04-27 JP JP2019514691A patent/JP7222347B2/ja active Active
- 2018-04-27 EP EP25168802.4A patent/EP4603507A3/en active Pending
- 2018-04-27 KR KR1020247022678A patent/KR20240111015A/ko active Pending
- 2018-04-27 EP EP18791007.0A patent/EP3617235A4/en active Pending
- 2018-04-27 KR KR1020197031664A patent/KR20200002858A/ko not_active Ceased
- 2018-04-27 WO PCT/JP2018/017345 patent/WO2018199337A1/ja not_active Ceased
- 2018-04-27 CA CA3061467A patent/CA3061467A1/en active Pending
- 2018-04-27 AU AU2018259856A patent/AU2018259856B2/en active Active
-
2019
- 2019-10-25 US US16/663,791 patent/US12024549B2/en active Active
-
2023
- 2023-02-03 JP JP2023015725A patent/JP7708133B2/ja active Active
-
2024
- 2024-05-16 US US18/666,145 patent/US20240366783A1/en active Pending
-
2025
- 2025-07-03 JP JP2025113314A patent/JP7754361B2/ja active Active
- 2025-07-22 AU AU2025206404A patent/AU2025206404A1/en active Pending
- 2025-10-02 JP JP2025166056A patent/JP2025185050A/ja active Pending
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