JP2022548699A - 置換フェニルボロン酸含有ポリマーおよび使用方法 - Google Patents

置換フェニルボロン酸含有ポリマーおよび使用方法 Download PDF

Info

Publication number
JP2022548699A
JP2022548699A JP2022517393A JP2022517393A JP2022548699A JP 2022548699 A JP2022548699 A JP 2022548699A JP 2022517393 A JP2022517393 A JP 2022517393A JP 2022517393 A JP2022517393 A JP 2022517393A JP 2022548699 A JP2022548699 A JP 2022548699A
Authority
JP
Japan
Prior art keywords
polymer
polymers
ring
occurrence
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2022517393A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022548699A5 (https=
JPWO2021055759A5 (https=
Inventor
トーマス ヘンリー ジョゼフィアック，
アシシュ ニムガオンカー，
スティーブン シー． ポロモスカニク，
Original Assignee
グライセンド， インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by グライセンド， インコーポレイテッド filed Critical グライセンド， インコーポレイテッド
Publication of JP2022548699A publication Critical patent/JP2022548699A/ja
Publication of JP2022548699A5 publication Critical patent/JP2022548699A5/ja
Publication of JPWO2021055759A5 publication Critical patent/JPWO2021055759A5/ja
Priority to JP2025138954A priority Critical patent/JP2025168413A/ja
Withdrawn legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C08F8/42—Introducing metal atoms or metal-containing groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/80—Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F216/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical
    • C08F216/02—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical by an alcohol radical
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/52—Amides or imides
    • C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
    • C08F220/56—Acrylamide; Methacrylamide
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/02—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a single or double bond to nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
    • C08F226/06—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F230/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal
    • C08F230/04—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal
    • C08F230/06—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal containing boron
    • C08F230/065—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal containing boron the monomer being a polymerisable borane, e.g. dimethyl(vinyl)borane
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F271/00—Macromolecular compounds obtained by polymerising monomers on to polymers of nitrogen-containing monomers as defined in group C08F26/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/0206—Polyalkylene(poly)amines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Polymers & Plastics (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
JP2022517393A 2019-09-20 2020-09-18 置換フェニルボロン酸含有ポリマーおよび使用方法 Withdrawn JP2022548699A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025138954A JP2025168413A (ja) 2019-09-20 2025-08-22 置換フェニルボロン酸含有ポリマーおよび使用方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962903328P 2019-09-20 2019-09-20
US62/903,328 2019-09-20
PCT/US2020/051506 WO2021055759A1 (en) 2019-09-20 2020-09-18 Substituted phenyl boronic acid containing polymers and methods of use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025138954A Division JP2025168413A (ja) 2019-09-20 2025-08-22 置換フェニルボロン酸含有ポリマーおよび使用方法

Publications (3)

Publication Number Publication Date
JP2022548699A true JP2022548699A (ja) 2022-11-21
JP2022548699A5 JP2022548699A5 (https=) 2023-09-28
JPWO2021055759A5 JPWO2021055759A5 (https=) 2023-09-28

Family

ID=74884712

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022517393A Withdrawn JP2022548699A (ja) 2019-09-20 2020-09-18 置換フェニルボロン酸含有ポリマーおよび使用方法
JP2025138954A Pending JP2025168413A (ja) 2019-09-20 2025-08-22 置換フェニルボロン酸含有ポリマーおよび使用方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025138954A Pending JP2025168413A (ja) 2019-09-20 2025-08-22 置換フェニルボロン酸含有ポリマーおよび使用方法

Country Status (11)

Country Link
US (7) US11576928B2 (https=)
EP (1) EP4031553A4 (https=)
JP (2) JP2022548699A (https=)
KR (1) KR20220065812A (https=)
CN (1) CN114423768A (https=)
AU (1) AU2020348451A1 (https=)
BR (1) BR112022004981A2 (https=)
CA (1) CA3150057A1 (https=)
IL (2) IL322632A (https=)
MX (1) MX2022003384A (https=)
WO (1) WO2021055759A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021055759A1 (en) 2019-09-20 2021-03-25 Glyscend, Inc. Substituted phenyl boronic acid containing polymers and methods of use
JP7850020B2 (ja) * 2022-06-28 2026-04-22 富士フイルム株式会社 高分子化合物、組成物、光学フィルムおよび光学積層体
CN116333197A (zh) * 2023-04-12 2023-06-27 厦门君德医药科技有限公司 胃肠道粘膜性聚合物、组合物及制备方法和应用
CN118593732B (zh) * 2024-06-27 2025-03-11 华中科技大学同济医学院附属同济医院 一种心肌炎核素分子探针及其制备方法和应用

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05310844A (ja) * 1992-05-08 1993-11-22 Nippon Oil & Fats Co Ltd フェニルボロン酸基含有重合体
JPH07126323A (ja) * 1993-11-05 1995-05-16 Nippon Oil & Fats Co Ltd フッ素化フェニルボロン酸基含有重合体
JPH11322761A (ja) * 1998-05-08 1999-11-24 Nof Corp ボロン酸基含有単量体およびその重合体
WO2009066746A1 (ja) * 2007-11-22 2009-05-28 The University Of Tokyo 組織癒着防止材および関節拘縮防止材
JP2011140537A (ja) * 2010-01-05 2011-07-21 Univ Of Tokyo フェニルボロン酸系単量体及びフェニルボロン酸系重合体
WO2017069282A1 (ja) * 2015-10-23 2017-04-27 国立大学法人東京医科歯科大学 薬剤送達用デバイス

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07304971A (ja) 1994-05-09 1995-11-21 Nippon Oil & Fats Co Ltd 糖応答性高分子材料
US6221425B1 (en) * 1998-01-30 2001-04-24 Advanced Cardiovascular Systems, Inc. Lubricious hydrophilic coating for an intracorporeal medical device
WO2001025291A1 (en) 1999-10-07 2001-04-12 University Of Maryland Sugar binding polymers and the use thereof
US7998412B2 (en) 2000-01-07 2011-08-16 Smart Holograms Limited Ophthalmic device comprising a holographic sensor
US7041280B2 (en) 2001-06-29 2006-05-09 Genzyme Corporation Aryl boronate functionalized polymers for treating obesity
US7662360B2 (en) 2002-07-22 2010-02-16 Psimei Pharmaceuticals Plc Conjugates of N-hydroxypropymethacrylamide-methacrylate copolymer with nuclide activation agent and/or anti-cancer compounds
AU2003291567A1 (en) 2002-11-19 2004-06-15 Genzyme Corporation Polymeric boronic acid derivatives as lipase inhibitors
GB0305587D0 (en) 2003-03-11 2003-04-16 Smart Holograms Ltd Sensor
EP1773900A4 (en) 2004-07-30 2007-08-29 Basf Ag POLYMERIC BORONIC ACID DERIVATIVES AND USE IN THE MANUFACTURE OF PAPER
JP2007177014A (ja) 2005-12-27 2007-07-12 Kawamura Inst Of Chem Res ホウ酸塩基含有アリルアミン重合体
US20080057086A1 (en) * 2006-09-01 2008-03-06 Pharmion Corporation Colon-targeted oral formulations of cytidine analogs
ES2375508T3 (es) * 2007-05-21 2012-03-01 Dow Global Technologies Llc Objetos recubiertos.
US8956556B2 (en) * 2008-07-02 2015-02-17 Eaton Corporation Dielectric isolators
WO2010041268A2 (en) 2008-09-02 2010-04-15 Usv Limited Crosslinked polymers
BR112012021448A2 (pt) 2010-02-24 2016-05-31 Relypsa Inc polímero de amina, método para tratar doença, método de remoção de sais biliares de um indivíduo animal, método para melhorar o controle glicêmico em um indivíduo, e, processo para preparar o polímero de amina.
WO2011106542A2 (en) 2010-02-24 2011-09-01 Relypsa, Inc. Crosslinked polyvrnylamine, poly all ylamine, and polyethyleneimine for use as bile acid sequestrants
DE112011100657T5 (de) 2010-02-24 2013-02-28 Relypsa, Inc. Amin-polymere zur verwendung als gallensäuresequestriermittel
JP5696961B2 (ja) 2010-05-26 2015-04-08 独立行政法人物質・材料研究機構 糖応答性ゲル及び薬剤投与デバイス
JP5398017B2 (ja) 2010-07-22 2014-01-29 国立大学法人 東京大学 検出デバイス及びバイオセンサ
US20130156720A1 (en) * 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
WO2012160975A1 (ja) 2011-05-20 2012-11-29 日産化学工業株式会社 感光性樹脂組成物
US9730637B2 (en) 2011-08-19 2017-08-15 The Regents Of The University Of California Layered particles for retrieving DNA released from cells from a gastrointestinal tract sample and methods for making and using them
WO2013073697A1 (ja) 2011-11-17 2013-05-23 国立大学法人 東京大学 フェニルボロン酸基が導入されたブロックコポリマーおよびその使用
WO2014122586A1 (en) 2013-02-08 2014-08-14 Wockhardt Limited Oral pharmaceutical composition of aliphatic amine polymer or salts thereof
US10716802B2 (en) 2013-03-15 2020-07-21 The Brigham And Women's Hospital, Inc. Compounds to modulate intestinal absorption of nutrients
WO2015120471A1 (en) 2014-02-10 2015-08-13 The Johns Hopkins University Devices for and methods of treatment of metabolic syndromes
CN103865060B (zh) 2014-03-20 2016-06-29 江南大学 一种含有苯硼酸官能团的高分子助留助滤剂的制备方法及其应用
MA41202A (fr) * 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2
US10683379B2 (en) * 2015-03-23 2020-06-16 Massachusetts Institute Of Technology Polymers, hydrogels, and uses thereof
WO2017024237A1 (en) 2015-08-06 2017-02-09 The Johns Hopkins University Composition and method for treatment of metabolic disorders
US10973846B2 (en) 2015-09-24 2021-04-13 The Brigham And Women's Hospital, Inc. Water-activated mucoadhesive compositions to reduce intestinal absorption of nutrients
WO2017061435A1 (ja) 2015-10-06 2017-04-13 国立研究開発法人物質・材料研究機構 ビニルアルコール樹脂機能化方法並びにビニルアルコール樹脂機能化剤
WO2017070617A1 (en) * 2015-10-21 2017-04-27 Case Western Reserve University Diol-modified insulin analogues containing a glucose-regulated conformational switch
JP6942142B2 (ja) 2015-12-14 2021-09-29 エコラブ ユーエスエイ インク 製紙プロセスのためのボロン酸含有ポリマー
EP3852768A4 (en) 2018-09-20 2022-09-14 Glyscend, Inc. BORONIC ACID POLYMERS AND METHODS OF USE
WO2021055752A1 (en) 2019-09-20 2021-03-25 Glyscend, Inc. Benzoxaborole polymers and methods of use
WO2021055759A1 (en) 2019-09-20 2021-03-25 Glyscend, Inc. Substituted phenyl boronic acid containing polymers and methods of use

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05310844A (ja) * 1992-05-08 1993-11-22 Nippon Oil & Fats Co Ltd フェニルボロン酸基含有重合体
JPH07126323A (ja) * 1993-11-05 1995-05-16 Nippon Oil & Fats Co Ltd フッ素化フェニルボロン酸基含有重合体
JPH11322761A (ja) * 1998-05-08 1999-11-24 Nof Corp ボロン酸基含有単量体およびその重合体
WO2009066746A1 (ja) * 2007-11-22 2009-05-28 The University Of Tokyo 組織癒着防止材および関節拘縮防止材
JP2011140537A (ja) * 2010-01-05 2011-07-21 Univ Of Tokyo フェニルボロン酸系単量体及びフェニルボロン酸系重合体
WO2017069282A1 (ja) * 2015-10-23 2017-04-27 国立大学法人東京医科歯科大学 薬剤送達用デバイス

Also Published As

Publication number Publication date
CA3150057A1 (en) 2021-03-25
US20220088063A1 (en) 2022-03-24
US20250032533A1 (en) 2025-01-30
KR20220065812A (ko) 2022-05-20
US11576928B2 (en) 2023-02-14
EP4031553A1 (en) 2022-07-27
IL291462B2 (en) 2026-01-01
IL322632A (en) 2025-10-01
MX2022003384A (es) 2022-06-27
US20220088062A1 (en) 2022-03-24
US20240082297A1 (en) 2024-03-14
CN114423768A (zh) 2022-04-29
US11491182B2 (en) 2022-11-08
US20220226366A1 (en) 2022-07-21
US11491183B2 (en) 2022-11-08
US11484548B2 (en) 2022-11-01
EP4031553A4 (en) 2023-11-01
IL291462A (en) 2022-05-01
JP2025168413A (ja) 2025-11-07
WO2021055759A1 (en) 2021-03-25
US12059432B2 (en) 2024-08-13
BR112022004981A2 (pt) 2022-06-21
US20230338415A1 (en) 2023-10-26
AU2020348451A1 (en) 2022-04-21
US20220265703A1 (en) 2022-08-25
IL291462B1 (en) 2025-09-01

Similar Documents

Publication Publication Date Title
US12059432B2 (en) Substituted phenyl boronic acid containing polymers and methods of use
JP7539374B2 (ja) ボロン酸ポリマーおよび使用方法
JP2025019142A (ja) ベンゾオキサボロールポリマーおよび使用方法
KR101052581B1 (ko) 음이온 결합성 중합체 및 그 용도
JPH06157671A (ja) 架橋、窒素含有ビニルコポリマー、その製造方法およびこれらの化合物の用途
EP2043627A2 (en) Iron(ii)-containing treatments for hyperphosphatemia
BRPI0715053A2 (pt) composiÇço farmacÊutica, mÉtodo para tratar doenÇas, e, polÍmero
US20140219951A1 (en) Amido-amine dendrimer compositions
US20100316589A1 (en) Coated Pharmaceutical Compositions
CN104204082B (zh) 高分子化氮氧化合物与无机颗粒的有机-无机杂合复合物
US20150283170A1 (en) Coated pharmaceutical compositions

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20230915

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20230915

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20240910

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20241002

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20241127

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20250423

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20250822

A761 Written withdrawal of application

Free format text: JAPANESE INTERMEDIATE CODE: A761

Effective date: 20250924