MX2022003384A - Polimeros que contienen acido fenil boronico sustituido y metodos de uso. - Google Patents
Polimeros que contienen acido fenil boronico sustituido y metodos de uso.Info
- Publication number
- MX2022003384A MX2022003384A MX2022003384A MX2022003384A MX2022003384A MX 2022003384 A MX2022003384 A MX 2022003384A MX 2022003384 A MX2022003384 A MX 2022003384A MX 2022003384 A MX2022003384 A MX 2022003384A MX 2022003384 A MX2022003384 A MX 2022003384A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- substituted phenyl
- boronic acid
- polymers containing
- phenyl boronic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/025—Boronic and borinic acid compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/42—Introducing metal atoms or metal-containing groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/80—Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F216/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical
- C08F216/02—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal or ketal radical by an alcohol radical
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
- C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
- C08F220/52—Amides or imides
- C08F220/54—Amides, e.g. N,N-dimethylacrylamide or N-isopropylacrylamide
- C08F220/56—Acrylamide; Methacrylamide
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
- C08F226/02—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a single or double bond to nitrogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F226/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen
- C08F226/06—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen by a heterocyclic ring containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F230/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal
- C08F230/04—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal
- C08F230/06—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal containing boron
- C08F230/065—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing a metal containing boron the monomer being a polymerisable borane, e.g. dimethyl(vinyl)borane
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F271/00—Macromolecular compounds obtained by polymerising monomers on to polymers of nitrogen-containing monomers as defined in group C08F26/00
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
- C08G73/02—Polyamines
- C08G73/0206—Polyalkylene(poly)amines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Polymers & Plastics (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962903328P | 2019-09-20 | 2019-09-20 | |
| PCT/US2020/051506 WO2021055759A1 (en) | 2019-09-20 | 2020-09-18 | Substituted phenyl boronic acid containing polymers and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2022003384A true MX2022003384A (es) | 2022-06-27 |
Family
ID=74884712
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2022003384A MX2022003384A (es) | 2019-09-20 | 2020-09-18 | Polimeros que contienen acido fenil boronico sustituido y metodos de uso. |
Country Status (11)
| Country | Link |
|---|---|
| US (7) | US11484548B2 (https=) |
| EP (1) | EP4031553A4 (https=) |
| JP (2) | JP2022548699A (https=) |
| KR (1) | KR20220065812A (https=) |
| CN (1) | CN114423768A (https=) |
| AU (1) | AU2020348451A1 (https=) |
| BR (1) | BR112022004981A2 (https=) |
| CA (1) | CA3150057A1 (https=) |
| IL (2) | IL322632A (https=) |
| MX (1) | MX2022003384A (https=) |
| WO (1) | WO2021055759A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2022003384A (es) | 2019-09-20 | 2022-06-27 | Glyscend Inc | Polimeros que contienen acido fenil boronico sustituido y metodos de uso. |
| JP7850020B2 (ja) * | 2022-06-28 | 2026-04-22 | 富士フイルム株式会社 | 高分子化合物、組成物、光学フィルムおよび光学積層体 |
| CN116333197A (zh) * | 2023-04-12 | 2023-06-27 | 厦门君德医药科技有限公司 | 胃肠道粘膜性聚合物、组合物及制备方法和应用 |
| CN118593732B (zh) * | 2024-06-27 | 2025-03-11 | 华中科技大学同济医学院附属同济医院 | 一种心肌炎核素分子探针及其制备方法和应用 |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05310844A (ja) * | 1992-05-08 | 1993-11-22 | Nippon Oil & Fats Co Ltd | フェニルボロン酸基含有重合体 |
| JP3427447B2 (ja) * | 1993-11-05 | 2003-07-14 | 日本油脂株式会社 | フッ素化フェニルボロン酸基含有重合体 |
| JPH07304971A (ja) | 1994-05-09 | 1995-11-21 | Nippon Oil & Fats Co Ltd | 糖応答性高分子材料 |
| US6221425B1 (en) * | 1998-01-30 | 2001-04-24 | Advanced Cardiovascular Systems, Inc. | Lubricious hydrophilic coating for an intracorporeal medical device |
| JP3867400B2 (ja) * | 1998-05-08 | 2007-01-10 | 日本油脂株式会社 | ボロン酸基含有単量体およびその重合体 |
| AU7856200A (en) | 1999-10-07 | 2001-05-10 | University Of Maryland | Sugar binding polymers and the use thereof |
| US7998412B2 (en) | 2000-01-07 | 2011-08-16 | Smart Holograms Limited | Ophthalmic device comprising a holographic sensor |
| US7041280B2 (en) | 2001-06-29 | 2006-05-09 | Genzyme Corporation | Aryl boronate functionalized polymers for treating obesity |
| US7662360B2 (en) | 2002-07-22 | 2010-02-16 | Psimei Pharmaceuticals Plc | Conjugates of N-hydroxypropymethacrylamide-methacrylate copolymer with nuclide activation agent and/or anti-cancer compounds |
| AU2003291567A1 (en) | 2002-11-19 | 2004-06-15 | Genzyme Corporation | Polymeric boronic acid derivatives as lipase inhibitors |
| GB0305587D0 (en) | 2003-03-11 | 2003-04-16 | Smart Holograms Ltd | Sensor |
| EP1773900A4 (en) | 2004-07-30 | 2007-08-29 | Basf Ag | POLYMERIC BORONIC ACID DERIVATIVES AND USE IN THE MANUFACTURE OF PAPER |
| JP2007177014A (ja) | 2005-12-27 | 2007-07-12 | Kawamura Inst Of Chem Res | ホウ酸塩基含有アリルアミン重合体 |
| US20080057086A1 (en) * | 2006-09-01 | 2008-03-06 | Pharmion Corporation | Colon-targeted oral formulations of cytidine analogs |
| CN101679655A (zh) * | 2007-05-21 | 2010-03-24 | 陶氏环球技术公司 | 涂布物体 |
| EP2226075A1 (en) * | 2007-11-22 | 2010-09-08 | The University of Tokyo | Material for preventing tissue adhesion and material for preventing joint contracture |
| US8956556B2 (en) * | 2008-07-02 | 2015-02-17 | Eaton Corporation | Dielectric isolators |
| BRPI0918499A2 (pt) | 2008-09-02 | 2015-12-01 | Usv Ltd | polímeros reticulados |
| JP5622188B2 (ja) * | 2010-01-05 | 2014-11-12 | 独立行政法人物質・材料研究機構 | フェニルボロン酸系単量体及びフェニルボロン酸系重合体 |
| WO2011106548A1 (en) | 2010-02-24 | 2011-09-01 | Relypsa, Inc. | Amine polymers for use as bile acid sequestrants |
| CN102858347B (zh) | 2010-02-24 | 2016-11-02 | 瑞立普萨公司 | 用作胆汁酸螯合剂的聚咪唑 |
| CN105017481B (zh) | 2010-02-24 | 2018-10-02 | 瑞立普萨公司 | 用作胆汁酸螯合剂的交联聚乙烯胺、聚烯丙胺和乙烯亚胺 |
| JP5696961B2 (ja) | 2010-05-26 | 2015-04-08 | 独立行政法人物質・材料研究機構 | 糖応答性ゲル及び薬剤投与デバイス |
| JP5398017B2 (ja) | 2010-07-22 | 2014-01-29 | 国立大学法人 東京大学 | 検出デバイス及びバイオセンサ |
| WO2012027331A1 (en) * | 2010-08-27 | 2012-03-01 | Ironwood Pharmaceuticals, Inc. | Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders |
| WO2012160975A1 (ja) | 2011-05-20 | 2012-11-29 | 日産化学工業株式会社 | 感光性樹脂組成物 |
| US9730637B2 (en) | 2011-08-19 | 2017-08-15 | The Regents Of The University Of California | Layered particles for retrieving DNA released from cells from a gastrointestinal tract sample and methods for making and using them |
| US9114177B2 (en) | 2011-11-17 | 2015-08-25 | The University Of Tokyo | Block copolymer having phenylboronic acid group introduced therein, and use thereof |
| WO2014122586A1 (en) | 2013-02-08 | 2014-08-14 | Wockhardt Limited | Oral pharmaceutical composition of aliphatic amine polymer or salts thereof |
| US10716802B2 (en) | 2013-03-15 | 2020-07-21 | The Brigham And Women's Hospital, Inc. | Compounds to modulate intestinal absorption of nutrients |
| WO2015120471A1 (en) | 2014-02-10 | 2015-08-13 | The Johns Hopkins University | Devices for and methods of treatment of metabolic syndromes |
| CN103865060B (zh) | 2014-03-20 | 2016-06-29 | 江南大学 | 一种含有苯硼酸官能团的高分子助留助滤剂的制备方法及其应用 |
| MA41202A (fr) * | 2014-12-18 | 2017-10-24 | Genzyme Corp | Copolymères polydiallymine réticulé pour le traitement du diabète de type 2 |
| WO2016154317A2 (en) * | 2015-03-23 | 2016-09-29 | Massachusetts Institute Of Technology | Polymers, hydrogels, and uses thereof |
| EP3331499A4 (en) | 2015-08-06 | 2019-04-10 | The Johns Hopkins University | COMPOSITION AND METHOD FOR THE TREATMENT OF METABOLISM DISEASES |
| EP3352738B1 (en) | 2015-09-24 | 2024-01-17 | The Brigham and Women's Hospital, Inc. | Water-activated mucoadhesive compositions to reduce intestinal absorption of nutrients |
| WO2017061435A1 (ja) | 2015-10-06 | 2017-04-13 | 国立研究開発法人物質・材料研究機構 | ビニルアルコール樹脂機能化方法並びにビニルアルコール樹脂機能化剤 |
| WO2017070617A1 (en) | 2015-10-21 | 2017-04-27 | Case Western Reserve University | Diol-modified insulin analogues containing a glucose-regulated conformational switch |
| US11141486B2 (en) * | 2015-10-23 | 2021-10-12 | National University Corporation Tokyo Medical And Dental University | Drug delivery device |
| US11035080B2 (en) | 2015-12-14 | 2021-06-15 | Ecolab Usa Inc. | Boronic acid containing polymers for papermaking process |
| WO2020061430A1 (en) * | 2018-09-20 | 2020-03-26 | Glyscend, Inc. | Boronic acid polymers and methods of use |
| MX2022003384A (es) | 2019-09-20 | 2022-06-27 | Glyscend Inc | Polimeros que contienen acido fenil boronico sustituido y metodos de uso. |
| EP4041740A4 (en) | 2019-09-20 | 2023-10-25 | Glyscend, Inc. | BENZOXABOROLE POLYMERS AND METHODS OF USE |
-
2020
- 2020-09-18 MX MX2022003384A patent/MX2022003384A/es unknown
- 2020-09-18 JP JP2022517393A patent/JP2022548699A/ja not_active Withdrawn
- 2020-09-18 IL IL322632A patent/IL322632A/en unknown
- 2020-09-18 EP EP20864507.7A patent/EP4031553A4/en not_active Withdrawn
- 2020-09-18 CN CN202080065462.5A patent/CN114423768A/zh active Pending
- 2020-09-18 BR BR112022004981A patent/BR112022004981A2/pt not_active Application Discontinuation
- 2020-09-18 IL IL291462A patent/IL291462B2/en unknown
- 2020-09-18 KR KR1020227012616A patent/KR20220065812A/ko not_active Ceased
- 2020-09-18 AU AU2020348451A patent/AU2020348451A1/en active Pending
- 2020-09-18 WO PCT/US2020/051506 patent/WO2021055759A1/en not_active Ceased
- 2020-09-18 CA CA3150057A patent/CA3150057A1/en active Pending
-
2021
- 2021-12-01 US US17/539,598 patent/US11484548B2/en active Active
- 2021-12-01 US US17/539,611 patent/US11576928B2/en active Active
-
2022
- 2022-04-07 US US17/715,625 patent/US11491183B2/en active Active
- 2022-04-07 US US17/715,619 patent/US11491182B2/en active Active
-
2023
- 2023-01-09 US US18/151,604 patent/US20230338415A1/en not_active Abandoned
- 2023-11-10 US US18/506,493 patent/US12059432B2/en active Active
-
2024
- 2024-06-27 US US18/756,151 patent/US20250032533A1/en active Pending
-
2025
- 2025-08-22 JP JP2025138954A patent/JP2025168413A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US11484548B2 (en) | 2022-11-01 |
| US12059432B2 (en) | 2024-08-13 |
| CA3150057A1 (en) | 2021-03-25 |
| US11576928B2 (en) | 2023-02-14 |
| BR112022004981A2 (pt) | 2022-06-21 |
| US20230338415A1 (en) | 2023-10-26 |
| US11491182B2 (en) | 2022-11-08 |
| AU2020348451A1 (en) | 2022-04-21 |
| US20220088063A1 (en) | 2022-03-24 |
| EP4031553A1 (en) | 2022-07-27 |
| IL291462B1 (en) | 2025-09-01 |
| CN114423768A (zh) | 2022-04-29 |
| JP2025168413A (ja) | 2025-11-07 |
| US20220226366A1 (en) | 2022-07-21 |
| IL322632A (en) | 2025-10-01 |
| US20240082297A1 (en) | 2024-03-14 |
| KR20220065812A (ko) | 2022-05-20 |
| US11491183B2 (en) | 2022-11-08 |
| WO2021055759A1 (en) | 2021-03-25 |
| IL291462A (en) | 2022-05-01 |
| JP2022548699A (ja) | 2022-11-21 |
| US20250032533A1 (en) | 2025-01-30 |
| EP4031553A4 (en) | 2023-11-01 |
| IL291462B2 (en) | 2026-01-01 |
| US20220088062A1 (en) | 2022-03-24 |
| US20220265703A1 (en) | 2022-08-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2022003384A (es) | Polimeros que contienen acido fenil boronico sustituido y metodos de uso. | |
| EA201591546A1 (ru) | Мультивалентные и моновалентные мультиспецифические комплексы и их применение | |
| BR112013005116A2 (pt) | moduladores e métodos de uso | |
| BR112013021134A2 (pt) | moduladores e métodos de uso | |
| UA116920C2 (uk) | Інгібітори fgfr4 | |
| MX373141B (es) | Anticuerpos anti-homologo relacionado con las convulsiones 6 (anti-sez6) y metodos de uso. | |
| CL2018000106A1 (es) | Moléculas de anticuerpo que se unen a cd45 | |
| EA201792613A1 (ru) | Модуляторы cot и способы их применения | |
| CO2017005842A2 (es) | Anticuerpos heterodiméricos que se unen a cd3 y cd38 | |
| MX356400B (es) | Moduladores novedosos y metodos de uso. | |
| MX384363B (es) | Nuevos polipéptidos de unión específica y usos de los mismos. | |
| EA201690405A1 (ru) | Аэрированные композиционные материалы, способы их получения и применения | |
| EA201390274A1 (ru) | Борсодержащие малые молекулы | |
| MX372679B (es) | Moleculas de union para bcma y cd3. | |
| EA201791007A3 (ru) | Соединения и их применения для модуляции гемоглобина | |
| GT201400147A (es) | Pirimidinas y triazinas fusionadas sustituidas y su uso | |
| BR112014027165A2 (pt) | antagonistas de st2l e métodos de uso | |
| BR112016004245A2 (pt) | moduladores de sez6 e métodos de uso | |
| EA201591426A1 (ru) | Соединения и их применения для модуляции гемоглобина | |
| CL2015002724A1 (es) | Métodos para tratar la enfermedad de crohn utilizando un anticuerpo anti-il23 | |
| PH12015501071A1 (en) | Combination therapy of anti-her3 antibodies | |
| CL2017002514A1 (es) | Anticuerpos anti-c1s humanizados y métodos para usarlos. | |
| MX380512B (es) | Formulación de revestimiento para madera. | |
| EA201170288A1 (ru) | Оксабициклогептаны и оксабициклогептены, их получение и применение | |
| NZ738538A (en) | 6-amino-quinoline-3-carbonitrils as cot modulators |