JP2022546101A5 - - Google Patents

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Publication number
JP2022546101A5
JP2022546101A5 JP2022513645A JP2022513645A JP2022546101A5 JP 2022546101 A5 JP2022546101 A5 JP 2022546101A5 JP 2022513645 A JP2022513645 A JP 2022513645A JP 2022513645 A JP2022513645 A JP 2022513645A JP 2022546101 A5 JP2022546101 A5 JP 2022546101A5
Authority
JP
Japan
Prior art keywords
cell preparation
cells
modified
cell
lymphocytes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022513645A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022546101A (ja
Filing date
Publication date
Priority claimed from PCT/US2019/049259 external-priority patent/WO2020047527A2/en
Application filed filed Critical
Priority claimed from PCT/US2020/048843 external-priority patent/WO2021042072A1/en
Publication of JP2022546101A publication Critical patent/JP2022546101A/ja
Publication of JP2022546101A5 publication Critical patent/JP2022546101A5/ja
Priority to JP2025185504A priority Critical patent/JP2026054469A/ja
Pending legal-status Critical Current

Links

JP2022513645A 2019-09-01 2020-08-31 リンパ球の改変および送達のための方法および組成物 Pending JP2022546101A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2025185504A JP2026054469A (ja) 2019-09-01 2025-11-04 リンパ球の改変および送達のための方法および組成物

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US201962894849P 2019-09-01 2019-09-01
US201962894853P 2019-09-01 2019-09-01
US201962894852P 2019-09-01 2019-09-01
US62/894,852 2019-09-01
US62/894,849 2019-09-01
US62/894,853 2019-09-01
US201962894926P 2019-09-02 2019-09-02
PCT/US2019/049259 WO2020047527A2 (en) 2018-09-02 2019-09-02 Methods and compositions for genetically modifying lymphocytes in blood or in enriched pbmcs
USPCT/US2019/049259 2019-09-02
US62/894,926 2019-09-02
US201962943207P 2019-12-03 2019-12-03
US62/943,207 2019-12-03
US202062985741P 2020-03-05 2020-03-05
US62/985,741 2020-03-05
PCT/US2020/048843 WO2021042072A1 (en) 2019-09-01 2020-08-31 Methods and compositions for the modification and delivery of lymphocytes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2025185504A Division JP2026054469A (ja) 2019-09-01 2025-11-04 リンパ球の改変および送達のための方法および組成物

Publications (2)

Publication Number Publication Date
JP2022546101A JP2022546101A (ja) 2022-11-02
JP2022546101A5 true JP2022546101A5 (https=) 2023-09-08

Family

ID=74686079

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2022513645A Pending JP2022546101A (ja) 2019-09-01 2020-08-31 リンパ球の改変および送達のための方法および組成物
JP2025185504A Pending JP2026054469A (ja) 2019-09-01 2025-11-04 リンパ球の改変および送達のための方法および組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2025185504A Pending JP2026054469A (ja) 2019-09-01 2025-11-04 リンパ球の改変および送達のための方法および組成物

Country Status (10)

Country Link
US (1) US20220340927A1 (https=)
EP (1) EP4022035A4 (https=)
JP (2) JP2022546101A (https=)
KR (1) KR20220070449A (https=)
CN (1) CN116057181A (https=)
AU (1) AU2020336230B2 (https=)
BR (1) BR112022003617A2 (https=)
CA (1) CA3152780A1 (https=)
MX (1) MX2022002521A (https=)
WO (1) WO2021042072A1 (https=)

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US11111505B2 (en) 2016-03-19 2021-09-07 Exuma Biotech, Corp. Methods and compositions for transducing lymphocytes and regulating the activity thereof
US11325948B2 (en) 2016-03-19 2022-05-10 Exuma Biotech Corp. Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL
US12590321B2 (en) 2016-03-19 2026-03-31 Exuma Biotech Corp. Methods and compositions for genetically modifying and expanding lymphocytes and regulating the activity thereof
CN113840911A (zh) * 2018-09-02 2021-12-24 埃克苏马生物技术公司 用于在血液中或在富集pbmc中基因修饰淋巴细胞的方法和组合物
WO2021231569A1 (en) * 2020-05-14 2021-11-18 Seattle Children's Hospital (dba Seattle Children's Research Institute) Dual promoter systems
WO2023015310A2 (en) * 2021-08-06 2023-02-09 Seattle Children's Hospital D/B/A Seattle Children's Research Institute T-cell manufacturing methods
EP4463135A2 (en) 2022-01-10 2024-11-20 Sana Biotechnology, Inc. Methods of ex vivo dosing and administration of lipid particles or viral vectors and related systems and uses
EP4469586A1 (en) * 2022-03-01 2024-12-04 Exuma Biotech Corp. Viral particles with membrane-bound hyaluronidase
WO2024026377A1 (en) 2022-07-27 2024-02-01 Sana Biotechnology, Inc. Methods of transduction using a viral vector and inhibitors of antiviral restriction factors
IL320156A (en) * 2022-10-10 2025-06-01 Kite Pharma Inc New large scale car-t immune cell manufacturing method utilizing lentiviral vector transfection
IL326194A (en) * 2023-07-31 2026-03-01 Bio4T2 Llc Methods for the expansion and in vivo uptake of CAR cells mediated by blood cells
EP4589007A1 (en) * 2024-01-17 2025-07-23 Revvity Gene Delivery GmbH Production of viral vectors
WO2025213071A1 (en) * 2024-04-05 2025-10-09 Baylor College Of Medicine Synthetic gene expression regulatory switches

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EA022752B1 (ru) * 2008-12-09 2016-02-29 Галозим, Инк. Длинные растворимые полипептиды рн20 и их использование
DK3129487T3 (da) * 2014-04-09 2020-11-30 Dna Twopointo Inc Forbedrede nukleinsyrekonstruktioner til eukaryot genekspression
JP6797803B2 (ja) * 2014-12-31 2020-12-09 セルジーン コーポレイション ナチュラルキラー細胞を用いて血液障害、固形腫瘍、又は感染性疾患を治療する方法
EP4286511A3 (en) * 2015-06-12 2024-03-06 Lentigen Technology, Inc. Method to treat cancer with engineered t-cells
CU24649B1 (es) * 2016-03-19 2023-02-13 Exuma Biotech Corp Retrovirus recombinantes incompetentes de replicación para la transducción de linfocitos y expansión regulada de los mismos
US11325948B2 (en) * 2016-03-19 2022-05-10 Exuma Biotech Corp. Methods and compositions for genetically modifying lymphocytes to express polypeptides comprising the intracellular domain of MPL
EP3439675A4 (en) * 2016-04-08 2019-12-18 Purdue Research Foundation METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY
CN107400664A (zh) * 2016-05-20 2017-11-28 蔡胜和 透明质酸酶的细胞表达及其在实体瘤细胞治疗中的应用
CA3030003A1 (en) * 2016-07-08 2018-01-11 F1 Oncology, Inc. Methods and compositions for transducing lymphocytes and regulating the activity thereof
BR112019002035A2 (pt) * 2016-08-01 2019-05-14 Novartis Ag tratamento de câncer usando um receptor de antígeno quimérico em combinação com um inibidor de uma molécula pró-macrófago m2
IL308824A (en) * 2016-08-17 2024-01-01 Factor Bioscience Inc Nucleic acid products and methods of administration thereof
WO2018075978A1 (en) * 2016-10-20 2018-04-26 Alpine Immune Sciences, Inc. Secretable variant immunomodulatory proteins and engineered cell therapy
EP3735460A4 (en) * 2017-09-18 2021-08-11 Exuma Biotech Corp. METHODS AND COMPOSITIONS FOR THE GENETIC MODIFICATION AND EXPANSION OF LYMPHOCYTES AND THE REGULATION OF THE ACTIVITY OF THE LATTER
CN107988183A (zh) * 2017-11-17 2018-05-04 杭州惠博士生物科技有限公司 一种重组人透明质酸及其生产方法
CN109913422A (zh) * 2017-12-13 2019-06-21 苏州康聚生物科技有限公司 一种包含肿瘤抗原识别受体的免疫细胞及其应用
EP3755347B1 (en) * 2018-02-21 2025-06-25 Board of Regents, The University of Texas System Universal antigen presenting cells and uses thereof

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