JP2022541436A5 - - Google Patents
Info
- Publication number
- JP2022541436A5 JP2022541436A5 JP2022502238A JP2022502238A JP2022541436A5 JP 2022541436 A5 JP2022541436 A5 JP 2022541436A5 JP 2022502238 A JP2022502238 A JP 2022502238A JP 2022502238 A JP2022502238 A JP 2022502238A JP 2022541436 A5 JP2022541436 A5 JP 2022541436A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- solvate
- pharmaceutically acceptable
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201962874606P | 2019-07-16 | 2019-07-16 | |
| US62/874,606 | 2019-07-16 | ||
| US201962944608P | 2019-12-06 | 2019-12-06 | |
| US62/944,608 | 2019-12-06 | ||
| PCT/US2020/042219 WO2021011713A1 (en) | 2019-07-16 | 2020-07-16 | Imidazopyrimidines as eed inhibitors and the use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022541436A JP2022541436A (ja) | 2022-09-26 |
| JP2022541436A5 true JP2022541436A5 (https=) | 2023-07-26 |
| JP7738909B2 JP7738909B2 (ja) | 2025-09-16 |
Family
ID=71895298
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022502238A Active JP7738909B2 (ja) | 2019-07-16 | 2020-07-16 | Ｅｅｄ阻害剤としてのイミダゾピリミジンおよびその使用 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US12145944B2 (https=) |
| EP (1) | EP3999510A1 (https=) |
| JP (1) | JP7738909B2 (https=) |
| KR (1) | KR102911673B1 (https=) |
| CN (2) | CN114127073B (https=) |
| AU (1) | AU2020315401B2 (https=) |
| BR (1) | BR112022000713A2 (https=) |
| CA (1) | CA3138560A1 (https=) |
| CL (1) | CL2022000093A1 (https=) |
| IL (1) | IL288872B1 (https=) |
| MX (1) | MX2022000550A (https=) |
| PE (1) | PE20220750A1 (https=) |
| PH (1) | PH12021553233A1 (https=) |
| TW (1) | TWI819225B (https=) |
| UA (1) | UA130084C2 (https=) |
| WO (1) | WO2021011713A1 (https=) |
| ZA (1) | ZA202109518B (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113636993B (zh) * | 2020-05-11 | 2022-08-19 | 苏州亚盛药业有限公司 | (5-氟-2,3-二氢苯并呋喃-4-基)甲胺或其盐的制备方法及其中间体 |
| CA3203975A1 (en) | 2020-12-03 | 2022-06-09 | Battelle Memorial Institute | Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery |
| CN115028631A (zh) * | 2021-03-05 | 2022-09-09 | 中国科学院上海药物研究所 | 三氮唑并嘧啶衍生物、其药物组合物及用途 |
| CN115212311B (zh) * | 2021-04-19 | 2024-08-09 | 苏州亚盛药业有限公司 | 一种药物组合及其用途 |
| TW202312995A (zh) * | 2021-08-11 | 2023-04-01 | 大陸商上海青煜醫藥科技有限公司 | 氮雜芳基化合物、其製備方法及應用 |
| JP2024529118A (ja) * | 2021-08-13 | 2024-08-01 | アセンテージ ファーマ（スーチョウ）カンパニー，リミティド | 疾患又は障害の治療方法 |
| CN116514814A (zh) * | 2022-01-30 | 2023-08-01 | 苏州亚盛药业有限公司 | 一种大环类化合物或其盐、溶剂合物的结晶形式或无定形形式 |
| CA3258934A1 (en) * | 2022-06-09 | 2023-12-14 | Battelle Memorial Institute | NON-VIRAL ADMINISTRATION OF SMALL MOLECULE THERAPEUTIC AGENTS |
| WO2024251197A1 (zh) | 2023-06-06 | 2024-12-12 | 苏州亚盛药业有限公司 | Eed抑制剂固体分散体、包含其的口服制剂及其制备方法 |
| AU2024353375A1 (en) | 2023-09-29 | 2026-04-09 | Battelle Memorial Institute | Polymer nanoparticle compositions for in vivo expression of polypeptides |
| WO2025113665A1 (zh) * | 2023-11-30 | 2025-06-05 | 上海海雁医药科技有限公司 | 稠四杂环衍生物及其药物组合物和用途 |
| WO2025122954A1 (en) | 2023-12-08 | 2025-06-12 | Battelle Memorial Institute | Use of dna origami nanostructures for molecular information based data storage systems |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5093330A (en) | 1987-06-15 | 1992-03-03 | Ciba-Geigy Corporation | Staurosporine derivatives substituted at methylamino nitrogen |
| JP2001523958A (ja) | 1997-03-21 | 2001-11-27 | ブライハム アンド ウィミンズ ホスピタル，インコーポレイテッド | 免疫療法のｃｔｌａ−４結合ペプチド |
| PL354286A1 (en) | 1999-08-23 | 2003-12-29 | Dana-Farber Cancer Institutedana-Farber Cancer Institute | Pd-1, a receptor for b7-4, and uses therefor |
| EP1212422B1 (en) | 1999-08-24 | 2007-02-21 | Medarex, Inc. | Human ctla-4 antibodies and their uses |
| AU2003281200A1 (en) | 2002-07-03 | 2004-01-23 | Tasuku Honjo | Immunopotentiating compositions |
| DK2439273T3 (da) | 2005-05-09 | 2019-06-03 | Ono Pharmaceutical Co | Humane monoklonale antistoffer til programmeret død-1(pd-1) og fremgangsmåder til behandling af cancer ved anvendelse af anti-pd-1- antistoffer alene eller i kombination med andre immunterapeutika |
| BR122017025062B8 (pt) | 2007-06-18 | 2021-07-27 | Merck Sharp & Dohme | anticorpo monoclonal ou fragmento de anticorpo para o receptor de morte programada humano pd-1, polinucleotídeo e composição compreendendo o referido anticorpo ou fragmento |
| AR072999A1 (es) | 2008-08-11 | 2010-10-06 | Medarex Inc | Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos |
| AU2009288730B2 (en) | 2008-08-25 | 2013-06-20 | Amplimmune, Inc. | Compositions of PD-1 antagonists and methods of use |
| EP3255060A1 (en) | 2008-12-09 | 2017-12-13 | F. Hoffmann-La Roche AG | Anti-pd-l1 antibodies and their use to enhance t-cell function |
| JP4965623B2 (ja) | 2009-09-30 | 2012-07-04 | インターナショナル・ビジネス・マシーンズ・コーポレーション | 所定のソフトウェアの実行パラメータを入力フィールドへ入力することを支援するための方法、システム、およびプログラム |
| US8907053B2 (en) | 2010-06-25 | 2014-12-09 | Aurigene Discovery Technologies Limited | Immunosuppression modulating compounds |
| WO2013006490A2 (en) | 2011-07-01 | 2013-01-10 | Cellerant Therapeutics, Inc. | Antibodies that specifically bind to tim3 |
| WO2013043569A1 (en) | 2011-09-20 | 2013-03-28 | Vical Incorporated | Synergistic anti-tumor efficacy using alloantigen combination immunotherapy |
| KR101764096B1 (ko) | 2011-11-28 | 2017-08-02 | 메르크 파텐트 게엠베하 | 항-ｐｄ-ｌ1 항체 및 그의 용도 |
| HK1203971A1 (en) | 2012-05-15 | 2015-11-06 | Bristol-Myers Squibb Company | Cancer immunotherapy by disrupting pd-1/pd-l1 signaling |
| UY34887A (es) | 2012-07-02 | 2013-12-31 | Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware | Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos |
| WO2014022332A1 (en) | 2012-07-31 | 2014-02-06 | The Brigham And Women's Hospital, Inc. | Modulation of the immune response |
| US10344088B2 (en) | 2013-03-15 | 2019-07-09 | Glaxosmithkline Intellectual Property Development Limited | Antigen binding proteins |
| WO2015036499A1 (en) | 2013-09-11 | 2015-03-19 | Medimmune Limited | Anti-b7-h1 antibodies for treating tumors |
| AU2015225867B2 (en) | 2014-03-07 | 2020-02-06 | University Health Network | Methods and compositions for modifying the immune response |
| KR102442436B1 (ko) | 2014-03-14 | 2022-09-15 | 노파르티스 아게 | Lag-3에 대한 항체 분자 및 그의 용도 |
| UY36462A (es) | 2014-12-23 | 2016-07-29 | Novartis Ag | Compuestos de triazolopirimidina y usos de los mismos |
| EP3472166A1 (en) | 2016-06-20 | 2019-04-24 | Novartis AG | Imidazopyrimidine compounds useful for the treatment of cancer |
| WO2017221092A1 (en) | 2016-06-20 | 2017-12-28 | Novartis Ag | Triazolopyridine compounds and uses thereof |
| JP7631193B2 (ja) | 2018-10-22 | 2025-02-18 | アルミス インコーポレイテッド | Ｔｙｋ２阻害剤およびその使用 |
| CA3142351A1 (en) | 2019-05-31 | 2020-12-03 | Ikena Oncology, Inc. | Tead inhibitors and uses thereof |
| CA3141826A1 (en) | 2019-05-31 | 2020-12-03 | Ikena Oncology, Inc. | Tead inhibitors and uses thereof |
| BR112022010924A2 (pt) | 2019-12-06 | 2022-09-06 | Vertex Pharma | Tetra-hidrofuranos substituídos como moduladores de canais de sódio |
-
2020
- 2020-07-16 PH PH1/2021/553233A patent/PH12021553233A1/en unknown
- 2020-07-16 BR BR112022000713A patent/BR112022000713A2/pt unknown
- 2020-07-16 EP EP20750129.7A patent/EP3999510A1/en active Pending
- 2020-07-16 KR KR1020227001061A patent/KR102911673B1/ko active Active
- 2020-07-16 TW TW109124012A patent/TWI819225B/zh active
- 2020-07-16 CA CA3138560A patent/CA3138560A1/en active Pending
- 2020-07-16 WO PCT/US2020/042219 patent/WO2021011713A1/en not_active Ceased
- 2020-07-16 MX MX2022000550A patent/MX2022000550A/es unknown
- 2020-07-16 CN CN202080051201.8A patent/CN114127073B/zh active Active
- 2020-07-16 UA UAA202200645A patent/UA130084C2/uk unknown
- 2020-07-16 US US16/971,472 patent/US12145944B2/en active Active
- 2020-07-16 AU AU2020315401A patent/AU2020315401B2/en active Active
- 2020-07-16 CN CN202410735099.3A patent/CN118745185A/zh active Pending
- 2020-07-16 PE PE2022000071A patent/PE20220750A1/es unknown
- 2020-07-16 IL IL288872A patent/IL288872B1/en unknown
- 2020-07-16 JP JP2022502238A patent/JP7738909B2/ja active Active
-
2021
- 2021-11-24 ZA ZA2021/09518A patent/ZA202109518B/en unknown
-
2022
- 2022-01-13 CL CL2022000093A patent/CL2022000093A1/es unknown
-
2024
- 2024-09-17 US US18/887,703 patent/US20250034162A1/en active Pending
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