JP2022536979A5 - - Google Patents

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Publication number
JP2022536979A5
JP2022536979A5 JP2021575994A JP2021575994A JP2022536979A5 JP 2022536979 A5 JP2022536979 A5 JP 2022536979A5 JP 2021575994 A JP2021575994 A JP 2021575994A JP 2021575994 A JP2021575994 A JP 2021575994A JP 2022536979 A5 JP2022536979 A5 JP 2022536979A5
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JP
Japan
Prior art keywords
compound
formula
crystalline
salt
ray powder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2021575994A
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English (en)
Japanese (ja)
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JP2022536979A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/038624 external-priority patent/WO2020257573A1/en
Publication of JP2022536979A publication Critical patent/JP2022536979A/ja
Publication of JP2022536979A5 publication Critical patent/JP2022536979A5/ja
Withdrawn legal-status Critical Current

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JP2021575994A 2019-06-21 2020-06-19 塩形態のベンペド酸及びそれを使用する方法 Withdrawn JP2022536979A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962864873P 2019-06-21 2019-06-21
US62/864,873 2019-06-21
PCT/US2020/038624 WO2020257573A1 (en) 2019-06-21 2020-06-19 Salt forms of bempedoic acid and methods for using the same

Publications (2)

Publication Number Publication Date
JP2022536979A JP2022536979A (ja) 2022-08-22
JP2022536979A5 true JP2022536979A5 (enExample) 2023-06-16

Family

ID=71528020

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2021575993A Pending JP2022537049A (ja) 2019-06-21 2020-06-19 ベンペド酸の製造方法及びその組成物
JP2021575994A Withdrawn JP2022536979A (ja) 2019-06-21 2020-06-19 塩形態のベンペド酸及びそれを使用する方法
JP2024211105A Pending JP2025032197A (ja) 2019-06-21 2024-12-04 ベンペド酸を含む製薬材料、医薬製剤及び医薬組成物
JP2026043961A Pending JP2026102795A (ja) 2019-06-21 2026-03-18 ベンペド酸の製造方法及びその組成物

Family Applications Before (1)

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JP2021575993A Pending JP2022537049A (ja) 2019-06-21 2020-06-19 ベンペド酸の製造方法及びその組成物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2024211105A Pending JP2025032197A (ja) 2019-06-21 2024-12-04 ベンペド酸を含む製薬材料、医薬製剤及び医薬組成物
JP2026043961A Pending JP2026102795A (ja) 2019-06-21 2026-03-18 ベンペド酸の製造方法及びその組成物

Country Status (13)

Country Link
US (11) US12344578B2 (enExample)
EP (3) EP3986860A1 (enExample)
JP (4) JP2022537049A (enExample)
KR (3) KR20220024815A (enExample)
CN (3) CN112437765A (enExample)
AU (3) AU2020296094B2 (enExample)
BR (1) BR112021025964A2 (enExample)
CA (2) CA3243601A1 (enExample)
ES (1) ES3032779T3 (enExample)
HU (1) HUE072061T2 (enExample)
IL (3) IL288909A (enExample)
MX (2) MX2021015936A (enExample)
WO (2) WO2020257573A1 (enExample)

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CN112437765A (zh) 2019-06-21 2021-03-02 艾斯柏伦治疗公司 贝派地酸的盐形式及其使用方法
US12528759B2 (en) 2019-10-03 2026-01-20 Synthon B.V. Crystalline forms of bempedoic acid
EP4069668A1 (en) 2019-12-06 2022-10-12 Synthon B.V. Crystalline forms of sodium salt of bempedoic acid
CN111559961A (zh) * 2020-05-26 2020-08-21 杭州科巢生物科技有限公司 一种贝派地酸晶型及其制备方法
WO2021255180A1 (en) * 2020-06-19 2021-12-23 Synthon B.V. Salts of bempedoic acid
CN112521282A (zh) * 2020-12-02 2021-03-19 苏州汉德创宏生化科技有限公司 一种贝派地酸中间体及其合成方法
WO2022149161A1 (en) * 2021-01-05 2022-07-14 Dr. Reddy's Laboratories Limited Process for preparation of bempedoic acid and its intermediates
JP2024521354A (ja) 2021-06-02 2024-05-31 エスペリオン・セラピューティクス・インコーポレイテッド ベンペド酸とトルバブタンを含む組成物及びそれらを用いた治療方法
CN115504914B (zh) * 2021-06-23 2024-05-07 武汉武药科技有限公司 一种贝派地酸中间体的制备方法
CN114436837B (zh) * 2021-12-27 2024-02-20 甘李药业股份有限公司 一种贝派地酸中间体的纯化方法
WO2023187833A1 (en) * 2022-03-30 2023-10-05 Enaltec Labs Private Limited A novel salt of bempedoic acid
CN117551009A (zh) * 2022-08-05 2024-02-13 武汉武药科技有限公司 一种贝派地酸中间体的合成方法
WO2024151311A1 (en) 2023-01-09 2024-07-18 Esperion Therapeutics, Inc. Methods of treatment using bempedoic acid
CN116589341A (zh) * 2023-04-14 2023-08-15 苏州汉德创宏生化科技有限公司 一种抗高血酯药物中间体的制备方法
TW202602886A (zh) 2024-03-20 2026-01-16 瑞典商阿斯特捷利康公司 Pcsk9抑制劑及其使用方法
TW202539678A (zh) 2024-03-20 2025-10-16 瑞典商阿斯特捷利康公司 Pcsk9抑制劑及其使用方法
TW202602866A (zh) 2024-03-20 2026-01-16 瑞典商阿斯特捷利康公司 Pcsk9抑制劑及其使用方法
TW202612699A (zh) 2024-05-16 2026-04-01 瑞典商阿斯特捷利康公司 組合療法
WO2026125708A1 (en) 2024-12-12 2026-06-18 Krka, D.D., Novo Mesto Tablets comprising bempedoic acid or bempedoic acid and ezetimibe

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CN112437765A (zh) 2019-06-21 2021-03-02 艾斯柏伦治疗公司 贝派地酸的盐形式及其使用方法
EP4069668A1 (en) * 2019-12-06 2022-10-12 Synthon B.V. Crystalline forms of sodium salt of bempedoic acid
WO2022149161A1 (en) 2021-01-05 2022-07-14 Dr. Reddy's Laboratories Limited Process for preparation of bempedoic acid and its intermediates

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