JP2022519711A5 - - Google Patents

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Publication number
JP2022519711A5
JP2022519711A5 JP2021546256A JP2021546256A JP2022519711A5 JP 2022519711 A5 JP2022519711 A5 JP 2022519711A5 JP 2021546256 A JP2021546256 A JP 2021546256A JP 2021546256 A JP2021546256 A JP 2021546256A JP 2022519711 A5 JP2022519711 A5 JP 2022519711A5
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JP
Japan
Prior art keywords
hsdh
dehydrogenated
steroid
genetically modified
bacterium
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JP2021546256A
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English (en)
Japanese (ja)
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JP2022519711A (ja
JP7661229B2 (ja
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Priority claimed from PCT/EP2020/053167 external-priority patent/WO2020161317A1/en
Publication of JP2022519711A publication Critical patent/JP2022519711A/ja
Publication of JP2022519711A5 publication Critical patent/JP2022519711A5/ja
Priority to JP2024218426A priority Critical patent/JP2025038080A/ja
Application granted granted Critical
Publication of JP7661229B2 publication Critical patent/JP7661229B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021546256A 2019-02-08 2020-02-07 ステロイドの１，２－脱水素のための微生物の生物工学的最適化 Active JP7661229B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024218426A JP2025038080A (ja) 2019-02-08 2024-12-13 ステロイドの１，２－脱水素のための微生物の生物工学的最適化

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP19305153 2019-02-08
EP19305153.9 2019-02-08
PCT/EP2020/053167 WO2020161317A1 (en) 2019-02-08 2020-02-07 Biotechnological optimization of microorganisms for the 1,2-dehydrogenation of steroids

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024218426A Division JP2025038080A (ja) 2019-02-08 2024-12-13 ステロイドの１，２－脱水素のための微生物の生物工学的最適化

Publications (3)

Publication Number Publication Date
JP2022519711A JP2022519711A (ja) 2022-03-24
JP2022519711A5 true JP2022519711A5 (https=) 2024-07-31
JP7661229B2 JP7661229B2 (ja) 2025-04-14

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ID=66554300

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021546256A Active JP7661229B2 (ja) 2019-02-08 2020-02-07 ステロイドの１，２－脱水素のための微生物の生物工学的最適化
JP2024218426A Withdrawn JP2025038080A (ja) 2019-02-08 2024-12-13 ステロイドの１，２－脱水素のための微生物の生物工学的最適化

Family Applications After (1)

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JP2024218426A Withdrawn JP2025038080A (ja) 2019-02-08 2024-12-13 ステロイドの１，２－脱水素のための微生物の生物工学的最適化

Country Status (14)

Country Link
US (1) US20220136029A1 (https=)
EP (1) EP3921414A1 (https=)
JP (2) JP7661229B2 (https=)
KR (1) KR20210125490A (https=)
CN (1) CN113423827A (https=)
AU (1) AU2020219424A1 (https=)
BR (1) BR112021015481A2 (https=)
CA (1) CA3128954A1 (https=)
IL (1) IL285386A (https=)
MX (1) MX2021009515A (https=)
SG (1) SG11202108529WA (https=)
TW (1) TWI852986B (https=)
WO (1) WO2020161317A1 (https=)
ZA (1) ZA202105566B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11202108529WA (en) * 2019-02-08 2021-09-29 Sanofi Sa Biotechnological optimization of microorganisms for the 1,2-dehydrogenation of steroids
CN118325997B (zh) * 2024-04-10 2025-07-22 湖南玉新药业有限公司 采用诺卡氏菌一步发酵生产泼尼松龙的方法
CN119464157B (zh) * 2025-01-13 2025-06-27 山东绿邦生物科技有限公司 居瘤胃棒状杆菌、微生物菌剂及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1232278A1 (en) * 1999-10-22 2002-08-21 Akzo Nobel N.V. MICROBIAL 9$g(a)-HYDROXYLATION OF STEROIDS
JP2007515490A (ja) * 2003-12-22 2007-06-14 アムジェン インコーポレーティッド アリールスルホンアミド化合物およびそれに関連する使用法
US20050239853A1 (en) * 2004-02-04 2005-10-27 Tjeerd Barf New compounds
WO2006124141A2 (en) * 2005-04-05 2006-11-23 Taro Pharmaceuticals North America, Inc. A process of preparing prednisolone devoid of steroid-derived impurities using recombinant e. coli transformed with a δ1-dehydrogenase gene
AU2013200516B2 (en) * 2006-07-12 2015-09-03 University Of Tennessee Research Foundation Substituted Acylanilides and Methods of Use Thereof
DK2084519T3 (da) * 2006-10-10 2012-08-20 Los Alamos Nat Security Llc Røntgenfluorescens-analysefremgangsmåde
CN106754775B (zh) * 2016-12-23 2019-08-20 华东理工大学 一种羰基还原酶突变体及其基因与应用
WO2018204764A1 (en) * 2017-05-05 2018-11-08 Camp4 Therapeutics Corporation Identification and targeted modulation of gene signaling networks
AU2019384074B2 (en) * 2018-11-20 2025-04-10 Sparrow Pharmaceuticals, Inc. Methods for administering corticosteroids
SG11202108529WA (en) * 2019-02-08 2021-09-29 Sanofi Sa Biotechnological optimization of microorganisms for the 1,2-dehydrogenation of steroids

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