MX2021009515A - Optimizacion biotecnologica de microorganismos para la 1,2-deshidrogenacion de esteroides. - Google Patents
Optimizacion biotecnologica de microorganismos para la 1,2-deshidrogenacion de esteroides.Info
- Publication number
- MX2021009515A MX2021009515A MX2021009515A MX2021009515A MX2021009515A MX 2021009515 A MX2021009515 A MX 2021009515A MX 2021009515 A MX2021009515 A MX 2021009515A MX 2021009515 A MX2021009515 A MX 2021009515A MX 2021009515 A MX2021009515 A MX 2021009515A
- Authority
- MX
- Mexico
- Prior art keywords
- dehydrogenation
- steroids
- biotechnological
- microorganisms
- optimization
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
- C12P33/02—Dehydrogenating; Dehydroxylating
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01053—3-Alpha (or 20-beta)-hydroxysteroid dehydrogenase (1.1.1.53)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
- C12Y103/99—Oxidoreductases acting on the CH-CH group of donors (1.3) with other acceptors (1.3.99)
- C12Y103/99004—3-Oxosteroid 1-dehydrogenase (1.3.99.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/365—Nocardia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP19305153 | 2019-02-08 | ||
| PCT/EP2020/053167 WO2020161317A1 (en) | 2019-02-08 | 2020-02-07 | Biotechnological optimization of microorganisms for the 1,2-dehydrogenation of steroids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2021009515A true MX2021009515A (es) | 2021-10-26 |
Family
ID=66554300
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2021009515A MX2021009515A (es) | 2019-02-08 | 2020-02-07 | Optimizacion biotecnologica de microorganismos para la 1,2-deshidrogenacion de esteroides. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20220136029A1 (https=) |
| EP (1) | EP3921414A1 (https=) |
| JP (2) | JP7661229B2 (https=) |
| KR (1) | KR20210125490A (https=) |
| CN (1) | CN113423827A (https=) |
| AU (1) | AU2020219424A1 (https=) |
| BR (1) | BR112021015481A2 (https=) |
| CA (1) | CA3128954A1 (https=) |
| IL (1) | IL285386A (https=) |
| MX (1) | MX2021009515A (https=) |
| SG (1) | SG11202108529WA (https=) |
| TW (1) | TWI852986B (https=) |
| WO (1) | WO2020161317A1 (https=) |
| ZA (1) | ZA202105566B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG11202108529WA (en) * | 2019-02-08 | 2021-09-29 | Sanofi Sa | Biotechnological optimization of microorganisms for the 1,2-dehydrogenation of steroids |
| CN118325997B (zh) * | 2024-04-10 | 2025-07-22 | 湖南玉新药业有限公司 | 采用诺卡氏菌一步发酵生产泼尼松龙的方法 |
| CN119464157B (zh) * | 2025-01-13 | 2025-06-27 | 山东绿邦生物科技有限公司 | 居瘤胃棒状杆菌、微生物菌剂及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1232278A1 (en) * | 1999-10-22 | 2002-08-21 | Akzo Nobel N.V. | MICROBIAL 9$g(a)-HYDROXYLATION OF STEROIDS |
| JP2007515490A (ja) * | 2003-12-22 | 2007-06-14 | アムジェン インコーポレーティッド | アリールスルホンアミド化合物およびそれに関連する使用法 |
| US20050239853A1 (en) * | 2004-02-04 | 2005-10-27 | Tjeerd Barf | New compounds |
| WO2006124141A2 (en) * | 2005-04-05 | 2006-11-23 | Taro Pharmaceuticals North America, Inc. | A process of preparing prednisolone devoid of steroid-derived impurities using recombinant e. coli transformed with a δ1-dehydrogenase gene |
| AU2013200516B2 (en) * | 2006-07-12 | 2015-09-03 | University Of Tennessee Research Foundation | Substituted Acylanilides and Methods of Use Thereof |
| DK2084519T3 (da) * | 2006-10-10 | 2012-08-20 | Los Alamos Nat Security Llc | Røntgenfluorescens-analysefremgangsmåde |
| CN106754775B (zh) * | 2016-12-23 | 2019-08-20 | 华东理工大学 | 一种羰基还原酶突变体及其基因与应用 |
| WO2018204764A1 (en) * | 2017-05-05 | 2018-11-08 | Camp4 Therapeutics Corporation | Identification and targeted modulation of gene signaling networks |
| AU2019384074B2 (en) * | 2018-11-20 | 2025-04-10 | Sparrow Pharmaceuticals, Inc. | Methods for administering corticosteroids |
| SG11202108529WA (en) * | 2019-02-08 | 2021-09-29 | Sanofi Sa | Biotechnological optimization of microorganisms for the 1,2-dehydrogenation of steroids |
-
2020
- 2020-02-07 SG SG11202108529WA patent/SG11202108529WA/en unknown
- 2020-02-07 TW TW109103905A patent/TWI852986B/zh active
- 2020-02-07 CA CA3128954A patent/CA3128954A1/en active Pending
- 2020-02-07 AU AU2020219424A patent/AU2020219424A1/en active Pending
- 2020-02-07 EP EP20702683.2A patent/EP3921414A1/en active Pending
- 2020-02-07 MX MX2021009515A patent/MX2021009515A/es unknown
- 2020-02-07 US US17/429,198 patent/US20220136029A1/en active Pending
- 2020-02-07 WO PCT/EP2020/053167 patent/WO2020161317A1/en not_active Ceased
- 2020-02-07 CN CN202080013236.2A patent/CN113423827A/zh active Pending
- 2020-02-07 JP JP2021546256A patent/JP7661229B2/ja active Active
- 2020-02-07 KR KR1020217025032A patent/KR20210125490A/ko not_active Ceased
- 2020-02-07 BR BR112021015481A patent/BR112021015481A2/pt unknown
-
2021
- 2021-08-04 IL IL285386A patent/IL285386A/en unknown
- 2021-08-06 ZA ZA2021/05566A patent/ZA202105566B/en unknown
-
2024
- 2024-12-13 JP JP2024218426A patent/JP2025038080A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| JP2025038080A (ja) | 2025-03-18 |
| US20220136029A1 (en) | 2022-05-05 |
| TW202045720A (zh) | 2020-12-16 |
| KR20210125490A (ko) | 2021-10-18 |
| ZA202105566B (en) | 2024-05-30 |
| JP2022519711A (ja) | 2022-03-24 |
| AU2020219424A1 (en) | 2021-08-26 |
| TWI852986B (zh) | 2024-08-21 |
| SG11202108529WA (en) | 2021-09-29 |
| CA3128954A1 (en) | 2020-08-13 |
| IL285386A (en) | 2021-09-30 |
| CN113423827A (zh) | 2021-09-21 |
| BR112021015481A2 (pt) | 2021-12-07 |
| EP3921414A1 (en) | 2021-12-15 |
| WO2020161317A1 (en) | 2020-08-13 |
| JP7661229B2 (ja) | 2025-04-14 |
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