JP2022519246A5 - - Google Patents

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Publication number
JP2022519246A5
JP2022519246A5 JP2021544511A JP2021544511A JP2022519246A5 JP 2022519246 A5 JP2022519246 A5 JP 2022519246A5 JP 2021544511 A JP2021544511 A JP 2021544511A JP 2021544511 A JP2021544511 A JP 2021544511A JP 2022519246 A5 JP2022519246 A5 JP 2022519246A5
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JP
Japan
Prior art keywords
antibody
sample
post
translational modification
target
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Pending
Application number
JP2021544511A
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English (en)
Japanese (ja)
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JP2022519246A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2020/015875 external-priority patent/WO2020160266A1/en
Publication of JP2022519246A publication Critical patent/JP2022519246A/ja
Publication of JP2022519246A5 publication Critical patent/JP2022519246A5/ja
Pending legal-status Critical Current

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JP2021544511A 2019-01-31 2020-01-30 抗体電荷不均一性についてのネイティブマイクロ流体ｃｅ－ｍｓ解析法 Pending JP2022519246A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962799331P 2019-01-31 2019-01-31
US62/799,331 2019-01-31
US201962851365P 2019-05-22 2019-05-22
US62/851,365 2019-05-22
PCT/US2020/015875 WO2020160266A1 (en) 2019-01-31 2020-01-30 Native microfluidic ce-ms analysis of antibody charge heterogeneity

Publications (2)

Publication Number Publication Date
JP2022519246A JP2022519246A (ja) 2022-03-22
JP2022519246A5 true JP2022519246A5 (https=) 2023-01-26

Family

ID=69811860

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021544511A Pending JP2022519246A (ja) 2019-01-31 2020-01-30 抗体電荷不均一性についてのネイティブマイクロ流体ｃｅ－ｍｓ解析法

Country Status (12)

Country Link
US (1) US12169203B2 (https=)
EP (1) EP3918339A1 (https=)
JP (1) JP2022519246A (https=)
KR (1) KR20210122803A (https=)
CN (1) CN113646638B (https=)
AU (1) AU2020216172A1 (https=)
BR (1) BR112021013716A2 (https=)
CA (1) CA3126712A1 (https=)
IL (1) IL284929A (https=)
MX (1) MX2021009267A (https=)
SG (1) SG11202108033TA (https=)
WO (1) WO2020160266A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114544839B (zh) * 2022-01-20 2024-08-20 未名生物医药有限公司 一种抗人神经生长因子抗体的电荷变异体检测方法
KR20240164561A (ko) * 2022-03-18 2024-11-19 리제너론 파아마슈티컬스, 인크. 폴리펩타이드 변종을 분석하기 위한 방법 및 시스템
WO2024020199A1 (en) * 2022-07-21 2024-01-25 Regeneron Pharmaceuticals, Inc. Native microfluidic ce-ms analysis of antibody charge heterogeneity
WO2025022284A1 (en) * 2023-07-25 2025-01-30 Dh Technologies Development Pte. Ltd. Method for in-capillary dissociation and analysis of mass spectral data

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2370749A1 (en) * 1999-04-20 2000-10-26 Target Discovery, Inc. Polypeptide fingerprinting methods, metabolic profiling, and bioinformatics database
FR2862134B1 (fr) * 2003-11-12 2007-07-27 Sebia Sa Analyse et typage de proteines monoclonales par electrophorese capillaire et immunodeplacement
CN101201355A (zh) * 2006-12-15 2008-06-18 许洋 免疫组质谱检测个体化肿瘤生物标志及疗效试剂盒和方法
US20100187113A1 (en) * 2009-01-26 2010-07-29 Vladislav Dolnik Capillary sieving electrophoresis with a cationic surfactant for size separation of proteins
MY192182A (en) 2009-06-26 2022-08-04 Regeneron Pharma Readily isolated bispecific antibodies with native immunoglobulin format
CN103033628A (zh) * 2012-12-18 2013-04-10 北京科技大学 制备个体全蛋白质组芯片的方法及其应用
EP3885368A1 (en) * 2015-05-12 2021-09-29 Regeneron Pharmaceuticals, Inc. Multimeric protein purity determination
GB201603291D0 (en) * 2016-02-25 2016-04-13 Binding Site Group The Ltd Antibodies
EP3602026B1 (en) * 2017-03-30 2025-10-08 908 Devices Inc. Microfluidic analysis of biological samples

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