JP2022518175A5 - - Google Patents

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Publication number
JP2022518175A5
JP2022518175A5 JP2021540023A JP2021540023A JP2022518175A5 JP 2022518175 A5 JP2022518175 A5 JP 2022518175A5 JP 2021540023 A JP2021540023 A JP 2021540023A JP 2021540023 A JP2021540023 A JP 2021540023A JP 2022518175 A5 JP2022518175 A5 JP 2022518175A5
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JP
Japan
Prior art keywords
xrpd pattern
solid form
form according
approximately
peaks
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
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JP2021540023A
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English (en)
Japanese (ja)
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JP2022518175A (ja
JP7483722B2 (ja
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Priority claimed from PCT/US2020/012687 external-priority patent/WO2020146463A1/en
Publication of JP2022518175A publication Critical patent/JP2022518175A/ja
Publication of JP2022518175A5 publication Critical patent/JP2022518175A5/ja
Application granted granted Critical
Publication of JP7483722B2 publication Critical patent/JP7483722B2/ja
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JP2021540023A 2019-01-09 2020-01-08 （ｓ）－４－（４－（４－（（（２－（２，６－ジオキソピペリジン－３－イル）－１－オキソイソインドリン－４－イル）オキシ）メチル）ベンジル）ピペラジン－１－イル）－３－フルオロベンゾニトリルを含む固体形態及びその塩、ならびにそれらを含む組成物及びその使用方法 Active JP7483722B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962790342P 2019-01-09 2019-01-09
US62/790,342 2019-01-09
PCT/US2020/012687 WO2020146463A1 (en) 2019-01-09 2020-01-08 Solid forms comprising (s)-4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl) benzyl)piperazin-1-yl)-3-fluorobenzonitrile and salts thereof, and compositions comprising and methods of using the same

Publications (3)

Publication Number Publication Date
JP2022518175A JP2022518175A (ja) 2022-03-14
JP2022518175A5 true JP2022518175A5 (https=) 2023-01-24
JP7483722B2 JP7483722B2 (ja) 2024-05-15

Family

ID=69467745

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021540023A Active JP7483722B2 (ja) 2019-01-09 2020-01-08 （ｓ）－４－（４－（４－（（（２－（２，６－ジオキソピペリジン－３－イル）－１－オキソイソインドリン－４－イル）オキシ）メチル）ベンジル）ピペラジン－１－イル）－３－フルオロベンゾニトリルを含む固体形態及びその塩、ならびにそれらを含む組成物及びその使用方法

Country Status (23)

Country Link
US (3) US11370777B2 (https=)
EP (2) EP3908582B1 (https=)
JP (1) JP7483722B2 (https=)
KR (1) KR102875111B1 (https=)
CN (3) CN113597425A (https=)
AU (1) AU2020206694B2 (https=)
BR (1) BR112021013435A2 (https=)
CA (1) CA3125756A1 (https=)
DK (1) DK3908582T3 (https=)
EA (1) EA202191620A1 (https=)
ES (1) ES3059967T3 (https=)
FI (1) FI3908582T3 (https=)
HR (1) HRP20260065T1 (https=)
IL (1) IL284680A (https=)
LT (1) LT3908582T (https=)
MX (1) MX2021008295A (https=)
PL (1) PL3908582T3 (https=)
PT (1) PT3908582T (https=)
RS (1) RS67646B1 (https=)
SG (1) SG11202107439XA (https=)
SI (1) SI3908582T1 (https=)
SM (1) SMT202600018T1 (https=)
WO (1) WO2020146463A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020146441A1 (en) * 2019-01-09 2020-07-16 Celgene Corporation Pharmaceutical compositions comprising (s)-4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)oxy)methyl) benzyl)piperazin-1-yl)-3-fluorobenzonitrile and methods of using the same
KR20220124228A (ko) * 2020-01-20 2022-09-13 강푸 바이오파마슈티칼즈 리미티드 이소인돌린 유도체, 및 이의 제약 조성물 및 용도
BR112023000817A2 (pt) * 2020-07-20 2023-02-07 Jiangsu Hengrui Pharmaceuticals Co Ltd Derivado de isoindolina contendo enxofre, e método de preparação do mesmo e uso médico do mesmo
KR20240013793A (ko) 2021-05-27 2024-01-30 셀진 코포레이션 조합 요법을 사용하는 다발성 골수종의 치료 방법
US20250368620A1 (en) * 2024-05-30 2025-12-04 Celgene Corporation ARNT Degrading Compounds and Uses Thereof

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DK2439273T3 (da) 2005-05-09 2019-06-03 Ono Pharmaceutical Co Humane monoklonale antistoffer til programmeret død-1(pd-1) og fremgangsmåder til behandling af cancer ved anvendelse af anti-pd-1- antistoffer alene eller i kombination med andre immunterapeutika
PT1907424E (pt) 2005-07-01 2015-10-09 Squibb & Sons Llc Anticorpos monoclonais humanos para o ligando 1 de morte programada (pd-l1)
BR122017025062B8 (pt) 2007-06-18 2021-07-27 Merck Sharp & Dohme anticorpo monoclonal ou fragmento de anticorpo para o receptor de morte programada humano pd-1, polinucleotídeo e composição compreendendo o referido anticorpo ou fragmento
EP2262837A4 (en) 2008-03-12 2011-04-06 Merck Sharp & Dohme PD-1 BINDING PROTEINS
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EP4467143B1 (en) * 2017-07-10 2026-03-11 Celgene Corporation Method for preparing 4-(4-(4-(((2-(2,6-dioxopiperidin-3-yl)-l-oxoisoindolin-4-yl)oxy)methyl)benzyl)piperazin-l-yl)-3-fluorobenzonitrile
KR102718800B1 (ko) 2018-05-23 2024-10-18 셀진 코포레이션 다발성 골수종의 치료 및 4-(4-(4-(((2-(2,6-디옥소피페리딘-3-일)-1-옥소이소인돌린-4-일)옥시)메틸)벤질)피페라진-1-일)-3-플루오로벤조니트릴에 대한 바이오마커의 용도
PL3796912T3 (pl) * 2018-05-23 2023-09-11 Celgene Corporation Związki przeciwproliferacyjne i przeciwciało bispecyficzne przeciwko bcma i cd3 do zastosowania kombinowanego

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