JP2022511127A5 - - Google Patents
Info
- Publication number
- JP2022511127A5 JP2022511127A5 JP2021551503A JP2021551503A JP2022511127A5 JP 2022511127 A5 JP2022511127 A5 JP 2022511127A5 JP 2021551503 A JP2021551503 A JP 2021551503A JP 2021551503 A JP2021551503 A JP 2021551503A JP 2022511127 A5 JP2022511127 A5 JP 2022511127A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- pharmaceutical composition
- composition according
- hydrogen
- cycloalkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862769844P | 2018-11-20 | 2018-11-20 | |
| US62/769,844 | 2018-11-20 | ||
| PCT/US2019/000069 WO2020106307A1 (en) | 2018-11-20 | 2019-11-20 | Aryl-aniline and heteroaryl-aniline compounds for treatment of birthmarks |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022511127A JP2022511127A (ja) | 2022-01-28 |
| JP2022511127A5 true JP2022511127A5 (https=) | 2023-09-12 |
| JP7651101B2 JP7651101B2 (ja) | 2025-03-26 |
Family
ID=70773018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021551503A Active JP7651101B2 (ja) | 2018-11-20 | 2019-11-20 | あざの処置のためのアリールアニリンおよびヘテロアリールアニリン化合物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20230013227A1 (https=) |
| EP (2) | EP4233834A3 (https=) |
| JP (1) | JP7651101B2 (https=) |
| CN (1) | CN113645964B (https=) |
| AU (1) | AU2019384064B2 (https=) |
| CA (1) | CA3120336A1 (https=) |
| MA (1) | MA55148A (https=) |
| WO (1) | WO2020106307A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3120351A1 (en) * | 2018-11-20 | 2020-05-28 | Nflection Therapeutics, Inc. | Aryl-aniline and heteroaryl-aniline compounds for treatment of skin cancers |
| WO2020106308A1 (en) | 2018-11-20 | 2020-05-28 | Nflection Therapeutics, Inc. | Naphthyridinone-aniline compounds for treatment of dermal disorders |
| WO2020106306A1 (en) | 2018-11-20 | 2020-05-28 | Nflection Therapeutics, Inc. | Cyanoaryl-aniline compounds for treatment of dermal disorders |
| WO2020106305A1 (en) * | 2018-11-20 | 2020-05-28 | Nflection Therapeutics, Inc. | Thienyl-aniline compounds for treatment of dermal disorders |
| EP4281055A4 (en) * | 2021-01-21 | 2025-06-18 | NFlection Therapeutics, Inc. | CRYSTALLINE FORMS OF A PYRROLOPYRIDINANILINE COMPOUND |
| EP4291235A4 (en) * | 2021-02-12 | 2025-01-08 | Nimbus Saturn, Inc. | HPK1 ANTAGONISTS AND USES THEREOF |
| WO2022213062A1 (en) | 2021-03-29 | 2022-10-06 | Nimbus Saturn, Inc. | Hpk1 antagonists and uses thereof |
| TWI825637B (zh) * | 2021-03-31 | 2023-12-11 | 美商輝瑞股份有限公司 | 啶－１，６（２ｈ，７ｈ）－二酮 |
| IL312977A (en) | 2021-11-23 | 2024-07-01 | Nflection Therapeutics Inc | Formulations of pyrrolopyridine-aniline compounds |
| WO2023096935A1 (en) * | 2021-11-23 | 2023-06-01 | Nflection Therapeutics, Inc. | Formulations of pyrrolopyridine-aniline compounds |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
| US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| HU196714B (en) | 1984-10-04 | 1989-01-30 | Monsanto Co | Process for producing non-aqueous composition comprising somatotropin |
| IE58110B1 (en) | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| IT1229203B (it) | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
| PH30995A (en) | 1989-07-07 | 1997-12-23 | Novartis Inc | Sustained release formulations of water soluble peptides. |
| US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5733566A (en) | 1990-05-15 | 1998-03-31 | Alkermes Controlled Therapeutics Inc. Ii | Controlled release of antiparasitic agents in animals |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| TW333456B (en) | 1992-12-07 | 1998-06-11 | Takeda Pharm Ind Co Ltd | A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide. |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| US6087324A (en) | 1993-06-24 | 2000-07-11 | Takeda Chemical Industries, Ltd. | Sustained-release preparation |
| IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| AU6242096A (en) | 1995-06-27 | 1997-01-30 | Takeda Chemical Industries Ltd. | Method of producing sustained-release preparation |
| TW448055B (en) | 1995-09-04 | 2001-08-01 | Takeda Chemical Industries Ltd | Method of production of sustained-release preparation |
| JP2909418B2 (ja) | 1995-09-18 | 1999-06-23 | 株式会社資生堂 | 薬物の遅延放出型マイクロスフイア |
| US5980945A (en) | 1996-01-16 | 1999-11-09 | Societe De Conseils De Recherches Et D'applications Scientifique S.A. | Sustained release drug formulations |
| US6264970B1 (en) | 1996-06-26 | 2001-07-24 | Takeda Chemical Industries, Ltd. | Sustained-release preparation |
| US6419961B1 (en) | 1996-08-29 | 2002-07-16 | Takeda Chemical Industries, Ltd. | Sustained release microcapsules of a bioactive substance and a biodegradable polymer |
| CA2217134A1 (en) | 1996-10-09 | 1998-04-09 | Sumitomo Pharmaceuticals Co., Ltd. | Sustained release formulation |
| PT839525E (pt) | 1996-10-31 | 2004-10-29 | Takeda Chemical Industries Ltd | Preparacao de libertacao prolongada |
| WO1998027980A2 (en) | 1996-12-20 | 1998-07-02 | Takeda Chemical Industries, Ltd. | Method of producing a sustained-release preparation |
| US5891474A (en) | 1997-01-29 | 1999-04-06 | Poli Industria Chimica, S.P.A. | Time-specific controlled release dosage formulations and method of preparing same |
| US6613358B2 (en) | 1998-03-18 | 2003-09-02 | Theodore W. Randolph | Sustained-release composition including amorphous polymer |
| KR19990085365A (ko) | 1998-05-16 | 1999-12-06 | 허영섭 | 지속적으로 약물 조절방출이 가능한 생분해성 고분자 미립구 및그 제조방법 |
| US6248363B1 (en) | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| CN1905873A (zh) * | 2003-11-19 | 2007-01-31 | 阵列生物制药公司 | Mek的杂环抑制剂及其使用方法 |
| JP5710855B2 (ja) | 2005-02-02 | 2015-04-30 | ネクスジェニクス・ファーマシューティカルズ，リミテッド・ライアビリティ・カンパニー | 神経線維腫の局所治療 |
| GB0616214D0 (en) * | 2006-08-15 | 2006-09-27 | Ucb Sa | Therapeutic Agents |
| CN101528231A (zh) * | 2006-08-16 | 2009-09-09 | 埃克塞利希斯股份有限公司 | 在癌症的治疗中使用pi3k和mek调控剂 |
| GB0801081D0 (en) * | 2008-01-21 | 2008-02-27 | Ucb Pharma Sa | Therapeutic agents |
| GB0811304D0 (en) * | 2008-06-19 | 2008-07-30 | Ucb Pharma Sa | Therapeutic agents |
| DE102010012594A1 (de) * | 2010-03-23 | 2011-09-29 | Beiersdorf Ag | Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an einem oder mehreren Thiazolderivaten |
| WO2012171484A1 (zh) * | 2011-06-17 | 2012-12-20 | 中国中化股份有限公司 | 一种取代氰基苯胺类化合物及制备与应用 |
| WO2014179263A1 (en) * | 2013-04-30 | 2014-11-06 | Allergan, Inc. | Therapeutic agents |
| JP7237941B2 (ja) * | 2017-05-19 | 2023-03-13 | エヌフレクション セラピューティクス インコーポレイテッド | 皮膚障害の処置用の融合複素環式芳香族アニリン化合物 |
| PT3624796T (pt) * | 2017-05-19 | 2025-06-02 | Nflection Therapeutics Inc | Compostos de pirrolopiridina-anilina para tratamento de distúrbios dérmicos |
| WO2020106306A1 (en) * | 2018-11-20 | 2020-05-28 | Nflection Therapeutics, Inc. | Cyanoaryl-aniline compounds for treatment of dermal disorders |
-
2019
- 2019-11-20 EP EP23178930.6A patent/EP4233834A3/en active Pending
- 2019-11-20 WO PCT/US2019/000069 patent/WO2020106307A1/en not_active Ceased
- 2019-11-20 US US17/294,793 patent/US20230013227A1/en not_active Abandoned
- 2019-11-20 JP JP2021551503A patent/JP7651101B2/ja active Active
- 2019-11-20 AU AU2019384064A patent/AU2019384064B2/en active Active
- 2019-11-20 CN CN201980089591.5A patent/CN113645964B/zh active Active
- 2019-11-20 EP EP19887611.2A patent/EP3883554A4/en active Pending
- 2019-11-20 CA CA3120336A patent/CA3120336A1/en active Pending
- 2019-11-20 MA MA055148A patent/MA55148A/fr unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2022511127A5 (https=) | ||
| JP2022513089A5 (https=) | ||
| CN103664899B (zh) | 杂芳基取代的二氢嘧啶类化合物及其在药物中的应用 | |
| ES2399314T3 (es) | Gamma lactamas sustituidas como agentes terapeúticos | |
| PH12022550584A1 (en) | Pyridine oxynitride, preparation method therefor and use thereof | |
| WO2017066227A1 (en) | Compounds useful as immunomodulators | |
| CN103626752A (zh) | 二氢嘧啶类化合物及其在药物中的应用 | |
| RU2015124002A (ru) | Соединения, применяемые в качестве ингибиторов индоламин-2,3-диоксигеназы | |
| CY1113269T1 (el) | Παραγωγα ινδαζολυλ αμιδιου για τη θεραπευτικη αγωγη διαταραχων διαμεσολαβουμενων υπο υποδοχεα γλυκοκορτικοειδων | |
| JP2012144537A5 (https=) | ||
| TWI703141B (zh) | 作為丙型肝炎抑制劑的化合物及其在藥物中的應用 | |
| EP2964231A1 (en) | Methods and compositions for transdermal delivery of caffeine in the forms of solution or suspension | |
| TW201538155A (zh) | 活性成份輔助組成物及將活性成份化合物遞送給對象之方法 | |
| ES2576980T3 (es) | Derivados químicos de jasmonato, composiciones farmacéuticas y métodos de uso de los mismos | |
| MX2024014315A (es) | Compuestos amido heteroaromaticos utiles en el tratamiento de enfermedades hepaticas | |
| JP2022511730A5 (https=) | ||
| KR100899491B1 (ko) | 티아졸릴 아미드의 국소 용도 | |
| EP2771324B1 (en) | Myxovirus therapeutics, compounds, and uses related thereto | |
| JP5979155B2 (ja) | システイン誘導体およびアルコールを含有する化粧料 | |
| RU2017140078A (ru) | Косметический способ и его терапевтическое применение для уменьшения объема жировой ткани | |
| RU2017134553A (ru) | Хорошо растворимые в воде соли фенилалкиламина - быстродействующего блокатора кальциевых каналов, и их применение | |
| WO2025049521A3 (en) | Aryl ether analogs as inhibitors of the menin-mll interaction | |
| CN103025707B (zh) | 泛醇基二十二碳六烯酸酯及其治疗和预防心血管疾病的用途 | |
| CN110049768B (zh) | 酚噻嗪衍生物及其使用方法 | |
| KR102435793B1 (ko) | 섬유증의 억제 또는 치료 방법 |