JP2022509358A5 - - Google Patents

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Publication number
JP2022509358A5
JP2022509358A5 JP2021547654A JP2021547654A JP2022509358A5 JP 2022509358 A5 JP2022509358 A5 JP 2022509358A5 JP 2021547654 A JP2021547654 A JP 2021547654A JP 2021547654 A JP2021547654 A JP 2021547654A JP 2022509358 A5 JP2022509358 A5 JP 2022509358A5
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JP
Japan
Prior art keywords
hydroxypropyl
cyclodextrin
composition
composition according
administered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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JP2021547654A
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English (en)
Japanese (ja)
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JP2022509358A (ja
JP7446322B2 (ja
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Priority claimed from PCT/US2019/057784 external-priority patent/WO2020092107A1/en
Publication of JP2022509358A publication Critical patent/JP2022509358A/ja
Publication of JP2022509358A5 publication Critical patent/JP2022509358A5/ja
Application granted granted Critical
Publication of JP7446322B2 publication Critical patent/JP7446322B2/ja
Active legal-status Critical Current
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JP2021547654A 2018-10-29 2019-10-24 アルツハイマー病を治療する方法 Active JP7446322B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862752131P 2018-10-29 2018-10-29
US62/752,131 2018-10-29
US201962885053P 2019-08-09 2019-08-09
US62/885,053 2019-08-09
PCT/US2019/057784 WO2020092107A1 (en) 2018-10-29 2019-10-24 Methods for treating alzheimer's disease

Publications (3)

Publication Number Publication Date
JP2022509358A JP2022509358A (ja) 2022-01-20
JP2022509358A5 true JP2022509358A5 (https=) 2022-10-28
JP7446322B2 JP7446322B2 (ja) 2024-03-08

Family

ID=68583503

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021547654A Active JP7446322B2 (ja) 2018-10-29 2019-10-24 アルツハイマー病を治療する方法

Country Status (10)

Country Link
US (3) US11925659B2 (https=)
EP (1) EP3873604B1 (https=)
JP (1) JP7446322B2 (https=)
KR (1) KR20210084480A (https=)
CN (1) CN112996562A (https=)
BR (1) BR112021008139A2 (https=)
CA (1) CA3114021C (https=)
ES (1) ES2992137T3 (https=)
PT (1) PT3873604T (https=)
WO (1) WO2020092107A1 (https=)

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CN111201030B (zh) 2017-07-25 2024-11-01 真和制药有限公司 通过阻断tim-3和其配体的相互作用治疗癌症
US11466008B2 (en) 2017-09-18 2022-10-11 Eip Pharma, Llc Co-crystals of neflamapimod (VX-745)
CN113490691A (zh) 2019-01-03 2021-10-08 劣势者药物有限公司 环糊精二聚体、其组合物及其用途
WO2020160156A2 (en) 2019-01-30 2020-08-06 Immutics, Inc. Anti-gal3 antibodies and uses thereof
EP4157338A4 (en) 2020-05-26 2024-11-13 TrueBinding, Inc. METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING
EP4157290A4 (en) * 2020-06-02 2024-06-05 National University of Singapore COMPOSITIONS, THEIR USES IN THERAPY AND METHODS THEREFOR
WO2022051631A1 (en) 2020-09-03 2022-03-10 University Of Notre Dame Du Lac Therapy to stimulate hippocampal neural progenitors and adult neurogenesis
WO2022099094A1 (en) * 2020-11-06 2022-05-12 Eip Pharma, Inc. Compositions and methods for treating depression
EP4240486A4 (en) * 2020-11-06 2024-05-22 EIP Pharma, Inc. TREATMENT OF GALKING DYSFUNCTION IN THE CONTEXT OF A NEURODEGENERATIVE DISEASE
US12285440B2 (en) 2021-03-14 2025-04-29 Massachusetts Institute Of Technology APOE4 impairs myelination via altered cholesterol biosynthesis and transport in oligodendroglia
WO2023089062A1 (en) * 2021-11-18 2023-05-25 Vib Vzw Improved gamma-secretase inhibitor screening assays
WO2023156966A1 (en) 2022-02-18 2023-08-24 Beren Therapeutics P.B.C. Compositions of hydroxypropyl-beta-cyclodextrin and methods of purifying the same
WO2023191425A1 (ko) * 2022-03-28 2023-10-05 주식회사 비엔에이치리서치 약물의 전기생리학적 스크리닝 방법
CN114569742B (zh) * 2022-05-09 2022-07-19 北京剂泰医药科技有限公司 一种组合物及其制备方法和应用
CA3259307A1 (en) * 2022-06-13 2023-12-21 Beren Therapeutics P.B.C. SYSTEMS AND METHODS FOR MANUFACTURING HYDROXYPROPYL-BETA-CYCLODEXTRIN
EP4561566A1 (en) * 2022-07-29 2025-06-04 Anavex Life Sciences Corp. Compositions and methods for prevention of cognitive decline caused by degenerative diseases
KR20250073473A (ko) * 2022-09-30 2025-05-27 싸이클로 테라퓨틱스, 아이엔씨. 조기 알츠하이머병 치료 방법
WO2025214478A1 (zh) * 2024-04-12 2025-10-16 北京华昊中天生物医药股份有限公司 一种优替德隆药物组合物及其制备方法

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
DE3346123A1 (de) 1983-12-21 1985-06-27 Janssen Pharmaceutica, N.V., Beerse Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung
US4877778A (en) 1987-07-01 1989-10-31 The Children's Medical Center Corporation Method of enhancing lipophile transport using cyclodextrin derivatives
US5569756A (en) 1995-03-21 1996-10-29 American Maize-Products Company Purification of chemically modified cyclodextrins
US8883494B2 (en) 2003-11-14 2014-11-11 Adil A. KHAN In vitro model for neuronal death
CN101674842A (zh) 2007-03-02 2010-03-17 普瑞芬医药有限公司 治疗阿尔茨海默氏病和痴呆的组合物和方法
MX371073B (es) 2012-04-13 2020-01-15 L&F Res Llc Método para utilizar ciclodextrina.
CN107865968B (zh) 2012-08-03 2021-03-05 美国政府(由卫生和人类服务部的部长所代表) 用于治疗溶酶体贮积症的环糊精
FR3014694B1 (fr) 2013-12-13 2016-11-11 Roquette Freres Compositions a base de methyl-cyclodextrines pour le traitement et/ou la prevention de maladies par augmentation du taux de cholesterol-hdl
US10413517B2 (en) 2014-06-12 2019-09-17 University Of Notre Dame Du Lac Composition and method for the treatment of neurological diseases and cerebral injury
WO2016168772A1 (en) 2015-04-17 2016-10-20 Sens Research Foundation, Inc. Cyclodextrin compounds for the prevention and treatment of aging
JP2018517046A (ja) 2015-06-10 2018-06-28 ビテス, インコーポレイテッド ヒドロキシプロピル−ベータ−シクロデキストリン組成物および方法
US20200000840A1 (en) * 2016-03-20 2020-01-02 Asdera Llc Use of cyclodextrins to reduce endocytosis in malignant and neurodegenerative disorders

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