|
US4889861A
(en)
|
1982-12-21 |
1989-12-26 |
Ciba-Geigy Corp. |
Substituted imidazo[1,5-a]pyridine derivatives and other substituted bicyclic derivatives and their use as aromatase inhibitors
|
|
US4617307A
(en)
|
1984-06-20 |
1986-10-14 |
Ciba-Geigy Corporation |
Substituted imidazo[1,5-A]pyridine derivatives as aromatase inhibitors
|
|
US5120712A
(en)
|
1986-05-05 |
1992-06-09 |
The General Hospital Corporation |
Insulinotropic hormone
|
|
US5118666A
(en)
|
1986-05-05 |
1992-06-02 |
The General Hospital Corporation |
Insulinotropic hormone
|
|
US5114946A
(en)
|
1987-06-12 |
1992-05-19 |
American Cyanamid Company |
Transdermal delivery of pharmaceuticals
|
|
US4818541A
(en)
|
1987-08-19 |
1989-04-04 |
Schering Corporation |
Transdermal delivery of enantiomers of phenylpropanolamine
|
|
ATE164852T1
(de)
|
1990-01-24 |
1998-04-15 |
Douglas I Buckley |
Glp-1-analoga verwendbar in der diabetesbehandlung
|
|
US5155100A
(en)
|
1991-05-01 |
1992-10-13 |
Ciba-Geigy Corporation |
Phosphono/biaryl substituted dipeptide derivatives
|
|
IL111785A0
(en)
|
1993-12-03 |
1995-01-24 |
Ferring Bv |
Dp-iv inhibitors and pharmaceutical compositions containing them
|
|
US5705483A
(en)
|
1993-12-09 |
1998-01-06 |
Eli Lilly And Company |
Glucagon-like insulinotropic peptides, compositions and methods
|
|
US5512549A
(en)
|
1994-10-18 |
1996-04-30 |
Eli Lilly And Company |
Glucagon-like insulinotropic peptide analogs, compositions, and methods of use
|
|
DE19616486C5
(de)
|
1996-04-25 |
2016-06-30 |
Royalty Pharma Collection Trust |
Verfahren zur Senkung des Blutglukosespiegels in Säugern
|
|
TW492957B
(en)
|
1996-11-07 |
2002-07-01 |
Novartis Ag |
N-substituted 2-cyanopyrrolidnes
|
|
CO5150173A1
(es)
|
1998-12-10 |
2002-04-29 |
Novartis Ag |
Compuestos n-(glicilo sustituido)-2-cianopirrolidinas inhibidores de peptidasa de dipeptidilo-iv (dpp-iv) los cuales son efectivos en el tratamiento de condiciones mediadas por la inhibicion de dpp-iv
|
|
IL152081A0
(en)
|
2000-04-12 |
2003-05-29 |
Novartis Ag |
Novel medical use of aldosterone synthase inhibitors alone or in combination with at1-receptor antagonists
|
|
TW200303742A
(en)
|
2001-11-21 |
2003-09-16 |
Novartis Ag |
Organic compounds
|
|
TW200407310A
(en)
|
2002-06-07 |
2004-05-16 |
Glaxo Group Ltd |
Compounds
|
|
EP1537114B8
(en)
|
2002-08-07 |
2007-10-03 |
Novartis AG |
Organic compounds as agents for the treatment of aldosterone mediated conditions
|
|
WO2004046145A1
(en)
|
2002-11-18 |
2004-06-03 |
Novartis Ag |
Imidazo[1, 5a]pyridine derivatives and methods for treating aldosterone mediated diseases
|
|
EP1638963B1
(en)
|
2003-05-20 |
2009-09-09 |
Novartis AG |
N-acyl nitrogen heterocycles as ligands of peroxisome proliferator-activated receptors
|
|
CN1997643A
(zh)
|
2004-05-28 |
2007-07-11 |
斯皮德尔实验股份公司 |
杂环化合物及其作为醛固酮合酶抑制剂的应用
|
|
CA2568159A1
(en)
|
2004-05-28 |
2005-12-15 |
Speedel Experimenta Ag |
Tetrahydro-imidazo [1,5-a] pyridin derivatives as aldosterone synthase inhibitors
|
|
AR050251A1
(es)
|
2004-05-28 |
2006-10-11 |
Speedel Experimenta Ag |
Compuestos heterociclicos con nitrogeno heteroatomico y composicion farmaceutica en base al compuesto
|
|
TW200611897A
(en)
|
2004-07-09 |
2006-04-16 |
Speedel Experimenta Ag |
Organic compounds
|
|
TW200716105A
(en)
|
2005-05-31 |
2007-05-01 |
Speedel Experimenta Ag |
Imidazole compounds
|
|
TW200716636A
(en)
|
2005-05-31 |
2007-05-01 |
Speedel Experimenta Ag |
Heterocyclic spiro-compounds
|
|
TW200716634A
(en)
|
2005-05-31 |
2007-05-01 |
Speedel Experimenta Ag |
Heterocyclic spiro-compounds
|
|
GT200600381A
(es)
|
2005-08-25 |
2007-03-28 |
|
Compuestos organicos
|
|
TW200804378A
(en)
|
2005-12-09 |
2008-01-16 |
Speedel Experimenta Ag |
Organic compounds
|
|
EP2402320A1
(en)
|
2006-03-31 |
2012-01-04 |
Novartis AG |
Anorectic agents
|
|
EP2009080A4
(en)
|
2006-04-04 |
2010-05-26 |
Taiyo Nippon Sanso Corp |
METHOD OF REMOVING METHANE, METHANE PARATOR AND METHOD USE SYSTEM
|
|
TW200808813A
(en)
|
2006-04-12 |
2008-02-16 |
Speedel Experimenta Ag |
Imidazo compounds
|
|
TW200808812A
(en)
|
2006-04-12 |
2008-02-16 |
Speedel Experimenta Ag |
Imidazo compounds
|
|
EP1886695A1
(en)
|
2006-06-27 |
2008-02-13 |
Speedel Experimenta AG |
Pharmaceutical combination of an aldosterone synthase inhibitor and a glucocorticoid receptor antagonist or a cortisol synthesis inhibitor or a corticotropin releasing factor antagonist
|
|
JP2010501573A
(ja)
|
2006-08-25 |
2010-01-21 |
ノバルティス アクチエンゲゼルシャフト |
アルドステロン合成酵素および/または11−β−ヒドロキシラーゼおよび/またはアロマターゼが介在する疾患の処置のための縮合イミダゾール誘導体
|
|
EP2094680A2
(en)
|
2006-12-18 |
2009-09-02 |
Novartis AG |
Imidazoles as aldosterone synthase inhibitors
|
|
WO2008076860A1
(en)
|
2006-12-18 |
2008-06-26 |
Novartis Ag |
4-imidazolyl-1,2,3,4-tetrahydroquinoline derivatives and their use as aldosterone/11-beta-hydroxylase inhibitors
|
|
CN101578272A
(zh)
|
2006-12-18 |
2009-11-11 |
诺瓦提斯公司 |
1-取代的咪唑衍生物和它们作为醛固酮合酶抑制剂的用途
|
|
PL2134720T3
(pl)
|
2007-03-29 |
2011-04-29 |
Novartis Ag |
Heterocykliczne spiro-związki
|
|
TWI448284B
(zh)
|
2007-04-24 |
2014-08-11 |
Theravance Inc |
雙效抗高血壓劑
|
|
JP2010538071A
(ja)
|
2007-09-07 |
2010-12-09 |
セラヴァンス, インコーポレーテッド |
二重作用性降圧剤
|
|
AR066169A1
(es)
|
2007-09-28 |
2009-07-29 |
Novartis Ag |
Derivados de benzo-imidazoles, utiles para trastornos asociados con la actividad de dgat
|
|
EP2297113A1
(en)
|
2008-04-29 |
2011-03-23 |
Theravance, Inc. |
Dual-acting antihypertensive agents
|
|
AR072297A1
(es)
|
2008-06-27 |
2010-08-18 |
Novartis Ag |
Derivados de indol-2-il-piridin-3-ilo, composicion farmaceutica que los comprende y su uso en medicamentos para el tratamiento de enfermedades mediadas por la sintasa aldosterona.
|
|
US9085527B2
(en)
*
|
2008-07-08 |
2015-07-21 |
Catabasis Pharmaceuticals, Inc. |
Fatty acid acylated salicylates and their uses
|
|
US8673270B2
(en)
*
|
2008-10-23 |
2014-03-18 |
Steba Biotech S.A. |
RGD-containing peptidomimetics and uses thereof
|
|
HRP20140371T1
(hr)
|
2009-05-15 |
2014-05-23 |
Novartis Ag |
Arilpiridini kao inhibitori sinteze aldosterona
|
|
CN103896796B
(zh)
|
2009-05-28 |
2016-04-27 |
诺华股份有限公司 |
作为脑啡肽酶抑制剂的取代的氨基丙酸衍生物
|
|
EP2435402B1
(en)
|
2009-05-28 |
2016-04-13 |
Novartis AG |
Substituted aminobutyric derivatives as neprilysin inhibitors
|
|
JO2967B1
(en)
|
2009-11-20 |
2016-03-15 |
نوفارتس ايه جي |
Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
|
|
US8877815B2
(en)
|
2010-11-16 |
2014-11-04 |
Novartis Ag |
Substituted carbamoylcycloalkyl acetic acid derivatives as NEP
|
|
US8673974B2
(en)
|
2010-11-16 |
2014-03-18 |
Novartis Ag |
Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors
|
|
US8586536B2
(en)
|
2010-12-15 |
2013-11-19 |
Theravance, Inc. |
Neprilysin inhibitors
|
|
KR101854874B1
(ko)
|
2011-02-17 |
2018-05-04 |
세라밴스 바이오파마 알앤디 아이피, 엘엘씨 |
네프릴리신 억제제로서 치환된 아미노부티릭 유도체
|
|
ES2653215T3
(es)
|
2011-05-31 |
2018-02-06 |
Theravance Biopharma R&D Ip, Llc |
Inhibidores de neprilisina
|
|
WO2012166389A1
(en)
|
2011-05-31 |
2012-12-06 |
Theravance, Inc. |
Neprilysin inhibitors
|
|
TWI560172B
(en)
|
2011-11-02 |
2016-12-01 |
Theravance Biopharma R&D Ip Llc |
Neprilysin inhibitors
|
|
MX356260B
(es)
|
2012-06-08 |
2018-05-21 |
Theravance Biopharma R&D Ip Llc |
Inhibidores de la neprilisina.
|
|
DE102012014480A1
(de)
|
2012-07-21 |
2014-01-23 |
Daimler Ag |
Aufbau eines Innendekors
|
|
MX366149B
(es)
|
2012-08-08 |
2019-06-28 |
Theravance Biopharma R&D Ip Llc |
Inhibidores de neprilisina.
|
|
CU24330B1
(es)
|
2013-02-14 |
2018-03-13 |
Novartis Ag |
Derivados del ácido 4-((1,1) bifenil-4-il)-3-(3-fosfonopropanamido) butanoico, activos como inhibidores de nep (endopeptidasa neutral)
|
|
CA2902456A1
(en)
|
2013-03-05 |
2014-09-12 |
Theravance Biopharma R&D Ip, Llc |
Neprilysin inhibitors
|
|
WO2014150395A1
(en)
*
|
2013-03-15 |
2014-09-25 |
Shifa Biomedical Corporation |
Anti-pcsk9 compounds and methods for the treatment and/or prevention of cardiovascular diseases
|
|
WO2015116786A1
(en)
|
2014-01-30 |
2015-08-06 |
Theravance Biopharma R&D Ip, Llc |
Neprilysin inhibitors
|
|
US9585882B2
(en)
|
2014-01-30 |
2017-03-07 |
Theravance Biopharma R&D Ip, Llc |
Neprilysin inhibitors
|