JP2022500418A5 - - Google Patents
Info
- Publication number
- JP2022500418A5 JP2022500418A5 JP2021513958A JP2021513958A JP2022500418A5 JP 2022500418 A5 JP2022500418 A5 JP 2022500418A5 JP 2021513958 A JP2021513958 A JP 2021513958A JP 2021513958 A JP2021513958 A JP 2021513958A JP 2022500418 A5 JP2022500418 A5 JP 2022500418A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cycloalkyl
- phenyl
- deuteroalkyl
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862730602P | 2018-09-13 | 2018-09-13 | |
| US62/730,602 | 2018-09-13 | ||
| PCT/US2019/050719 WO2020056072A1 (en) | 2018-09-13 | 2019-09-12 | 1h-indazole carboxamides as receptor-interacting protein kinase 1 inhibitors (ripk1) |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022500418A JP2022500418A (ja) | 2022-01-04 |
| JP2022500418A5 true JP2022500418A5 (enExample) | 2022-09-05 |
| JP7599411B2 JP7599411B2 (ja) | 2024-12-13 |
Family
ID=68073171
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021513958A Active JP7599411B2 (ja) | 2018-09-13 | 2019-09-12 | 受容体相互作用タンパク質キナーゼ１阻害剤（ｒｉｐｋ１）としての１ｈ－インダゾールカルボキサミド |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US12172975B2 (enExample) |
| EP (1) | EP3849968B1 (enExample) |
| JP (1) | JP7599411B2 (enExample) |
| KR (1) | KR102906523B1 (enExample) |
| CN (1) | CN112673000B (enExample) |
| AU (1) | AU2019337612A1 (enExample) |
| BR (1) | BR112021004385A2 (enExample) |
| CA (1) | CA3112735A1 (enExample) |
| EA (1) | EA202190718A1 (enExample) |
| ES (1) | ES2936481T3 (enExample) |
| IL (1) | IL281370A (enExample) |
| MX (1) | MX2021002509A (enExample) |
| SG (1) | SG11202102405YA (enExample) |
| WO (1) | WO2020056072A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3704118T3 (da) | 2017-10-30 | 2022-03-14 | Bristol Myers Squibb Co | Aminoimidazopyrazin som kinasehæmmere |
| SG11202007035YA (en) | 2018-01-26 | 2020-08-28 | Bristol Myers Squibb Co | Aminopyrrolotriazines as kinase inhibitors |
| EP3849969B1 (en) | 2018-09-13 | 2023-04-19 | Bristol-Myers Squibb Company | Indazole carboxamides as kinase inhibitors |
| WO2021067654A1 (en) * | 2019-10-03 | 2021-04-08 | Bristol-Myers Squibb Company | Indazole carboxamides as kinase inhibitors |
| KR20230067669A (ko) * | 2020-09-15 | 2023-05-16 | 주식회사 퍼스트바이오테라퓨틱스 | 2-아미노-3-카르보닐 이미다조피리딘 및 피라졸로피리딘 화합물 |
| AR123793A1 (es) | 2020-10-19 | 2023-01-11 | Bristol Myers Squibb Co | Compuestos de triazolopiridinilo como inhibidores de quinasas |
| WO2025106362A1 (en) * | 2023-11-16 | 2025-05-22 | Merck Sharp & Dohme Llc | Ripk1 inhibitors and methods of use |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1648455A4 (en) | 2003-07-23 | 2009-03-04 | Exelixis Inc | MODULATORS OF ALK PROTEIN (ANAPLASTIC LYMPHOMA KINASE) AND METHODS OF USE |
| CA2591817A1 (en) | 2004-12-22 | 2006-06-29 | Memory Pharmaceuticals Corporation | Nicotinic alpha-7 receptor ligands and preparation and uses thereof |
| PL2018380T3 (pl) | 2006-05-19 | 2012-05-31 | Abbvie Bahamas Ltd | Skondensowane azabicykliczne pochodne alkanowe podstawione bicykloheterocyklem o aktywności wobec OUN |
| KR101061599B1 (ko) | 2008-12-05 | 2011-09-02 | 한국과학기술연구원 | 비정상 세포 성장 질환의 치료를 위한 단백질 키나아제 저해제인 신규 인다졸 유도체, 이의 약학적으로 허용가능한염 및 이를 유효성분으로 함유하는 약학적 조성물 |
| US20110237633A1 (en) | 2008-12-11 | 2011-09-29 | Bijoy Panicker | Small molecule modulators of hepatocyte growth factor (scatter factor) activity |
| CA2759083A1 (en) | 2009-04-30 | 2010-11-04 | Novartis Ag | Imidazole derivatives and their use as modulators of cyclin dependent kinases |
| US8455516B2 (en) | 2010-01-15 | 2013-06-04 | Touro University | HIV-1 fusion inhibitors and methods |
| KR20130077390A (ko) * | 2011-12-29 | 2013-07-09 | 제이더블유중외제약 주식회사 | 단백질 키나아제 저해활성을 가지는 6-아미노-3-카복스아미도인다졸 유도체 |
| BR112014018657B1 (pt) | 2012-02-21 | 2022-08-02 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A | Compostos de 1h-indazol-3-carboxamida |
| AU2013224302B2 (en) | 2012-02-21 | 2017-03-30 | Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. | 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors |
| US9783573B2 (en) | 2012-09-18 | 2017-10-10 | Bristol-Myers Squibb Company | IAP antagonists |
| JP6215338B2 (ja) | 2012-11-08 | 2017-10-18 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | キナーゼモジュレーターとして有用な二環式ヘテロ環置換ピリジル化合物 |
| CN106535890A (zh) | 2014-03-20 | 2017-03-22 | 萨穆梅德有限公司 | 5‑取代的吲唑‑3‑羧酰胺及其制备和应用 |
| WO2017201585A1 (en) | 2016-05-26 | 2017-11-30 | Genea Ip Holdings Pty Ltd | Modulators of dux4 for regulation of muscle function |
| EP3580220B1 (en) | 2017-02-13 | 2021-11-17 | Bristol-Myers Squibb Company | Aminotriazolopyridines as kinase inhibitors |
| DK3704118T3 (da) | 2017-10-30 | 2022-03-14 | Bristol Myers Squibb Co | Aminoimidazopyrazin som kinasehæmmere |
| SG11202007035YA (en) | 2018-01-26 | 2020-08-28 | Bristol Myers Squibb Co | Aminopyrrolotriazines as kinase inhibitors |
| EP3849969B1 (en) * | 2018-09-13 | 2023-04-19 | Bristol-Myers Squibb Company | Indazole carboxamides as kinase inhibitors |
| WO2021067654A1 (en) | 2019-10-03 | 2021-04-08 | Bristol-Myers Squibb Company | Indazole carboxamides as kinase inhibitors |
-
2019
- 2019-09-12 EP EP19779240.1A patent/EP3849968B1/en active Active
- 2019-09-12 US US17/274,220 patent/US12172975B2/en active Active
- 2019-09-12 SG SG11202102405YA patent/SG11202102405YA/en unknown
- 2019-09-12 CA CA3112735A patent/CA3112735A1/en active Pending
- 2019-09-12 AU AU2019337612A patent/AU2019337612A1/en not_active Abandoned
- 2019-09-12 WO PCT/US2019/050719 patent/WO2020056072A1/en not_active Ceased
- 2019-09-12 EA EA202190718A patent/EA202190718A1/ru unknown
- 2019-09-12 BR BR112021004385-3A patent/BR112021004385A2/pt not_active Application Discontinuation
- 2019-09-12 MX MX2021002509A patent/MX2021002509A/es unknown
- 2019-09-12 ES ES19779240T patent/ES2936481T3/es active Active
- 2019-09-12 JP JP2021513958A patent/JP7599411B2/ja active Active
- 2019-09-12 KR KR1020217010498A patent/KR102906523B1/ko active Active
- 2019-09-12 CN CN201980059445.8A patent/CN112673000B/zh active Active
-
2021
- 2021-03-09 IL IL281370A patent/IL281370A/en unknown
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