JP2022501334A5 - - Google Patents

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Publication number
JP2022501334A5
JP2022501334A5 JP2021513960A JP2021513960A JP2022501334A5 JP 2022501334 A5 JP2022501334 A5 JP 2022501334A5 JP 2021513960 A JP2021513960 A JP 2021513960A JP 2021513960 A JP2021513960 A JP 2021513960A JP 2022501334 A5 JP2022501334 A5 JP 2022501334A5
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JP
Japan
Prior art keywords
alkyl
salt
alkoxy
cycloalkyl
compound according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021513960A
Other languages
English (en)
Japanese (ja)
Other versions
JP7434294B2 (ja
JP2022501334A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/050721 external-priority patent/WO2020056074A1/en
Publication of JP2022501334A publication Critical patent/JP2022501334A/ja
Publication of JP2022501334A5 publication Critical patent/JP2022501334A5/ja
Application granted granted Critical
Publication of JP7434294B2 publication Critical patent/JP7434294B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021513960A 2018-09-13 2019-09-12 キナーゼ阻害剤としてのインダゾールカルボキサミド Active JP7434294B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862730611P 2018-09-13 2018-09-13
US62/730,611 2018-09-13
PCT/US2019/050721 WO2020056074A1 (en) 2018-09-13 2019-09-12 Indazole carboxamides as kinase inhibitors

Publications (3)

Publication Number Publication Date
JP2022501334A JP2022501334A (ja) 2022-01-06
JP2022501334A5 true JP2022501334A5 (enExample) 2022-09-05
JP7434294B2 JP7434294B2 (ja) 2024-02-20

Family

ID=68073172

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021513960A Active JP7434294B2 (ja) 2018-09-13 2019-09-12 キナーゼ阻害剤としてのインダゾールカルボキサミド

Country Status (14)

Country Link
US (1) US12084426B2 (enExample)
EP (1) EP3849969B1 (enExample)
JP (1) JP7434294B2 (enExample)
KR (1) KR102793119B1 (enExample)
CN (1) CN112673001B (enExample)
AU (1) AU2019339355A1 (enExample)
BR (1) BR112021004310A2 (enExample)
CA (1) CA3112519A1 (enExample)
EA (1) EA202190759A1 (enExample)
ES (1) ES2945220T3 (enExample)
IL (1) IL281371A (enExample)
MX (1) MX2021002617A (enExample)
SG (1) SG11202102406XA (enExample)
WO (1) WO2020056074A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3704118T3 (da) 2017-10-30 2022-03-14 Bristol Myers Squibb Co Aminoimidazopyrazin som kinasehæmmere
SG11202007035YA (en) 2018-01-26 2020-08-28 Bristol Myers Squibb Co Aminopyrrolotriazines as kinase inhibitors
EP3849968B1 (en) 2018-09-13 2022-12-21 Bristol-Myers Squibb Company 1h-indazole carboxamides as receptor-interacting protein kinase 1 inhibitors (ripk1)
EP3849969B1 (en) 2018-09-13 2023-04-19 Bristol-Myers Squibb Company Indazole carboxamides as kinase inhibitors
GB201905721D0 (en) 2019-04-24 2019-06-05 Univ Dundee Compounds
WO2021067654A1 (en) * 2019-10-03 2021-04-08 Bristol-Myers Squibb Company Indazole carboxamides as kinase inhibitors
AR123793A1 (es) 2020-10-19 2023-01-11 Bristol Myers Squibb Co Compuestos de triazolopiridinilo como inhibidores de quinasas
KR20230100646A (ko) 2021-12-24 2023-07-05 제일약품주식회사 Ripk1 저해제로서의 신규한 화합물 및 이를 포함하는 약학적 조성물

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1648455A4 (en) 2003-07-23 2009-03-04 Exelixis Inc MODULATORS OF ALK PROTEIN (ANAPLASTIC LYMPHOMA KINASE) AND METHODS OF USE
CA2591817A1 (en) 2004-12-22 2006-06-29 Memory Pharmaceuticals Corporation Nicotinic alpha-7 receptor ligands and preparation and uses thereof
PL2018380T3 (pl) 2006-05-19 2012-05-31 Abbvie Bahamas Ltd Skondensowane azabicykliczne pochodne alkanowe podstawione bicykloheterocyklem o aktywności wobec OUN
US8648069B2 (en) 2007-06-08 2014-02-11 Abbvie Inc. 5-substituted indazoles as kinase inhibitors
KR101061599B1 (ko) 2008-12-05 2011-09-02 한국과학기술연구원 비정상 세포 성장 질환의 치료를 위한 단백질 키나아제 저해제인 신규 인다졸 유도체, 이의 약학적으로 허용가능한염 및 이를 유효성분으로 함유하는 약학적 조성물
US20110237633A1 (en) 2008-12-11 2011-09-29 Bijoy Panicker Small molecule modulators of hepatocyte growth factor (scatter factor) activity
US8455516B2 (en) 2010-01-15 2013-06-04 Touro University HIV-1 fusion inhibitors and methods
KR20130077390A (ko) * 2011-12-29 2013-07-09 제이더블유중외제약 주식회사 단백질 키나아제 저해활성을 가지는 6-아미노-3-카복스아미도인다졸 유도체
BR112014018657B1 (pt) 2012-02-21 2022-08-02 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A Compostos de 1h-indazol-3-carboxamida
AU2013224302B2 (en) 2012-02-21 2017-03-30 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. 1H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors
US9783573B2 (en) 2012-09-18 2017-10-10 Bristol-Myers Squibb Company IAP antagonists
WO2017201585A1 (en) 2016-05-26 2017-11-30 Genea Ip Holdings Pty Ltd Modulators of dux4 for regulation of muscle function
ES2902995T3 (es) * 2016-10-07 2022-03-30 Bristol Myers Squibb Co Compuestos de imidazopiridazina útiles como moduladores de respuestas a IL-12, IL-23 y/o IFN alfa
EP3580220B1 (en) 2017-02-13 2021-11-17 Bristol-Myers Squibb Company Aminotriazolopyridines as kinase inhibitors
DK3704118T3 (da) 2017-10-30 2022-03-14 Bristol Myers Squibb Co Aminoimidazopyrazin som kinasehæmmere
SG11202007035YA (en) 2018-01-26 2020-08-28 Bristol Myers Squibb Co Aminopyrrolotriazines as kinase inhibitors
EP3849968B1 (en) 2018-09-13 2022-12-21 Bristol-Myers Squibb Company 1h-indazole carboxamides as receptor-interacting protein kinase 1 inhibitors (ripk1)
EP3849969B1 (en) 2018-09-13 2023-04-19 Bristol-Myers Squibb Company Indazole carboxamides as kinase inhibitors
WO2021067654A1 (en) 2019-10-03 2021-04-08 Bristol-Myers Squibb Company Indazole carboxamides as kinase inhibitors

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