JP2022079484A5 - - Google Patents
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- JP2022079484A5 JP2022079484A5 JP2022035111A JP2022035111A JP2022079484A5 JP 2022079484 A5 JP2022079484 A5 JP 2022079484A5 JP 2022035111 A JP2022035111 A JP 2022035111A JP 2022035111 A JP2022035111 A JP 2022035111A JP 2022079484 A5 JP2022079484 A5 JP 2022079484A5
- Authority
- JP
- Japan
- Prior art keywords
- human
- cells
- preparation
- rpe cells
- human rpe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 210000004027 cell Anatomy 0.000 claims 27
- 101000670189 Homo sapiens Ribulose-phosphate 3-epimerase Proteins 0.000 claims 19
- 239000000825 pharmaceutical preparation Substances 0.000 claims 9
- 238000000338 in vitro Methods 0.000 claims 6
- 201000007737 Retinal degeneration Diseases 0.000 claims 3
- 108091008695 photoreceptors Proteins 0.000 claims 3
- 230000004258 retinal degeneration Effects 0.000 claims 3
- 108050002823 Bestrophin Proteins 0.000 claims 2
- 102000012304 Bestrophin Human genes 0.000 claims 2
- 101001078886 Homo sapiens Retinaldehyde-binding protein 1 Proteins 0.000 claims 2
- 101150092239 OTX2 gene Proteins 0.000 claims 2
- 102100035846 Pigment epithelium-derived factor Human genes 0.000 claims 2
- 102100028001 Retinaldehyde-binding protein 1 Human genes 0.000 claims 2
- 210000001671 embryonic stem cell Anatomy 0.000 claims 2
- 210000004263 induced pluripotent stem cell Anatomy 0.000 claims 2
- 208000002780 macular degeneration Diseases 0.000 claims 2
- 239000011159 matrix material Substances 0.000 claims 2
- 108090000102 pigment epithelium-derived factor Proteins 0.000 claims 2
- 210000001778 pluripotent stem cell Anatomy 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- 239000000725 suspension Substances 0.000 claims 2
- 208000035719 Maculopathy Diseases 0.000 claims 1
- 208000007014 Retinitis pigmentosa Diseases 0.000 claims 1
- 108060007030 Ribulose-phosphate 3-epimerase Proteins 0.000 claims 1
- 206010064930 age-related macular degeneration Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000000007 visual effect Effects 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024205622A JP2025036424A (ja) | 2007-10-12 | 2024-11-26 | Ｒｐｅ細胞を生成する改良された方法およびｒｐｅ細胞の組成物 |
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US99866807P | 2007-10-12 | 2007-10-12 | |
| US99876607P | 2007-10-12 | 2007-10-12 | |
| US60/998,668 | 2007-10-12 | ||
| US60/998,766 | 2007-10-12 | ||
| US990808P | 2008-01-02 | 2008-01-02 | |
| US991108P | 2008-01-02 | 2008-01-02 | |
| US61/009,911 | 2008-01-02 | ||
| US61/009,908 | 2008-01-02 | ||
| JP2020072683A JP2020115882A (ja) | 2007-10-12 | 2020-04-15 | Ｒｐｅ細胞を生成する改良された方法およびｒｐｅ細胞の組成物 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020072683A Division JP2020115882A (ja) | 2007-10-12 | 2020-04-15 | Ｒｐｅ細胞を生成する改良された方法およびｒｐｅ細胞の組成物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024205622A Division JP2025036424A (ja) | 2007-10-12 | 2024-11-26 | Ｒｐｅ細胞を生成する改良された方法およびｒｐｅ細胞の組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022079484A JP2022079484A (ja) | 2022-05-26 |
| JP2022079484A5 true JP2022079484A5 (cg-RX-API-DMAC7.html) | 2022-11-10 |
Family
ID=40567677
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010528899A Withdrawn JP2011500024A (ja) | 2007-10-12 | 2008-10-10 | Ｒｐｅ細胞を生成する改良された方法およびｒｐｅ細胞の組成物 |
| JP2014125977A Active JP6137626B2 (ja) | 2007-10-12 | 2014-06-19 | Ｒｐｅ細胞を生成する改良された方法およびｒｐｅ細胞の組成物 |
| JP2017083243A Active JP6692768B2 (ja) | 2007-10-12 | 2017-04-19 | Ｒｐｅ細胞を生成する改良された方法およびｒｐｅ細胞の組成物 |
| JP2020072683A Pending JP2020115882A (ja) | 2007-10-12 | 2020-04-15 | Ｒｐｅ細胞を生成する改良された方法およびｒｐｅ細胞の組成物 |
| JP2022035111A Pending JP2022079484A (ja) | 2007-10-12 | 2022-03-08 | Ｒｐｅ細胞を生成する改良された方法およびｒｐｅ細胞の組成物 |
| JP2024205622A Pending JP2025036424A (ja) | 2007-10-12 | 2024-11-26 | Ｒｐｅ細胞を生成する改良された方法およびｒｐｅ細胞の組成物 |
Family Applications Before (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010528899A Withdrawn JP2011500024A (ja) | 2007-10-12 | 2008-10-10 | Ｒｐｅ細胞を生成する改良された方法およびｒｐｅ細胞の組成物 |
| JP2014125977A Active JP6137626B2 (ja) | 2007-10-12 | 2014-06-19 | Ｒｐｅ細胞を生成する改良された方法およびｒｐｅ細胞の組成物 |
| JP2017083243A Active JP6692768B2 (ja) | 2007-10-12 | 2017-04-19 | Ｒｐｅ細胞を生成する改良された方法およびｒｐｅ細胞の組成物 |
| JP2020072683A Pending JP2020115882A (ja) | 2007-10-12 | 2020-04-15 | Ｒｐｅ細胞を生成する改良された方法およびｒｐｅ細胞の組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024205622A Pending JP2025036424A (ja) | 2007-10-12 | 2024-11-26 | Ｒｐｅ細胞を生成する改良された方法およびｒｐｅ細胞の組成物 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US20110274662A1 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2209888B1 (cg-RX-API-DMAC7.html) |
| JP (6) | JP2011500024A (cg-RX-API-DMAC7.html) |
| KR (2) | KR101849329B1 (cg-RX-API-DMAC7.html) |
| CN (2) | CN104946591A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2008312007A1 (cg-RX-API-DMAC7.html) |
| CA (3) | CA2702386C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2209888T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2764473T3 (cg-RX-API-DMAC7.html) |
| IL (4) | IL292561A (cg-RX-API-DMAC7.html) |
| PL (1) | PL2209888T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2209888T (cg-RX-API-DMAC7.html) |
| WO (1) | WO2009051671A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (56)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| EP4248752A3 (en) * | 2004-01-23 | 2024-01-03 | President And Fellows Of Harvard College | Improved modalities for the treatment of degenerative diseases of the retina |
| US9133435B2 (en) | 2007-01-18 | 2015-09-15 | Riken | Method for induction/differentiation into photoreceptor cell |
| KR101849329B1 (ko) | 2007-10-12 | 2018-04-16 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | Ｒｐｅ 세포의 개선된 생산 방법 및 ｒｐｅ 세포의 조성물 |
| WO2009132156A1 (en) * | 2008-04-22 | 2009-10-29 | Regenerative Research Foundation | Retinal pigment epithelial stem cells |
| EP2314671B1 (en) | 2008-06-06 | 2022-08-03 | Riken | Method for culture of stem cell |
| EP2470673B1 (en) * | 2009-08-28 | 2014-07-30 | Cellular Dynamics International, Inc. | Identifying genetic variation in affected tissues |
| WO2011055855A1 (en) * | 2009-11-05 | 2011-05-12 | Riken | A method for differentiation induction in cultured stem cells |
| US10485829B2 (en) | 2009-11-17 | 2019-11-26 | Astellas Institute For Regenerative Medicine | Methods of producing human RPE cells and pharmaceutical preparations of human RPE cells |
| ES2758554T3 (es) | 2009-12-08 | 2020-05-05 | Univ Case Western Reserve | Aminoácidos gama para tratamiento de trastornos oculares |
| HUE054517T2 (hu) * | 2010-07-23 | 2021-09-28 | Astellas Inst For Regenerative Medicine | Eljárások sejtek ritka alpopulációinak detektálására és nagymértékben tisztított sejtkészítmények |
| FI20106354A0 (fi) * | 2010-12-20 | 2010-12-20 | Suomen Punainen Risti Veripalvelu | Menetelmä ihmisen retinan pigmentti-epiteelisolujen valmistamiseksi |
| CN111265551A (zh) | 2011-05-18 | 2020-06-12 | 加利福尼亚大学董事会 | 用于治疗视网膜疾病的组合物及方法 |
| IL320536A (en) * | 2011-11-14 | 2025-06-01 | Astellas Inst For Regenerative Medicine | Pharmaceutical preparations of human RPE cells and their use |
| JP5985209B2 (ja) * | 2011-11-25 | 2016-09-06 | 住友化学株式会社 | 眼杯様構造体の製造方法 |
| JP6067232B2 (ja) * | 2011-11-25 | 2017-01-25 | 住友化学株式会社 | 網膜層特異的神経細胞を製造する方法 |
| JP5985207B2 (ja) * | 2011-11-25 | 2016-09-06 | 住友化学株式会社 | 網膜色素上皮細胞の製造方法 |
| JP6012164B2 (ja) * | 2011-11-25 | 2016-10-25 | 住友化学株式会社 | 多能性幹細胞由来の組織の凍結保存方法 |
| JP5985208B2 (ja) * | 2011-11-25 | 2016-09-06 | 住友化学株式会社 | 網膜組織の製造方法 |
| CA2856867C (en) * | 2011-11-25 | 2021-06-01 | Sumitomo Chemical Company, Limited | Methods for producing retinal tissue and retina-related cell |
| US8961956B2 (en) | 2011-11-30 | 2015-02-24 | Ocata Therapeutics, Inc. | Mesenchymal stromal cells and uses related thereto |
| CA2857545A1 (en) | 2011-11-30 | 2013-06-06 | Advanced Cell Technology, Inc. | Mesenchymal stromal cells and uses related thereto |
| US10519422B2 (en) * | 2012-02-29 | 2019-12-31 | Riken | Method of producing human retinal pigment epithelial cells |
| WO2014011407A2 (en) | 2012-07-12 | 2014-01-16 | Imstem Biotechnology, Inc. | Mesenchymal-like stem cells derived from human embryonic stem cells, methods and uses thereof |
| ES2896354T3 (es) | 2012-12-21 | 2022-02-24 | Astellas Inst For Regenerative Medicine | Métodos para la producción de plaquetas a partir de células madre pluripotentes |
| AU2014212230B2 (en) | 2013-02-01 | 2019-07-04 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Method for generating retinal pigment epithelium (RPE) cells from induced pluripotent stem cells (iPSCs) |
| AU2014246962A1 (en) * | 2013-04-03 | 2015-11-19 | Tampereen Yliopisto | Methods and media for differentiating eye cells |
| WO2015025967A1 (ja) | 2013-08-23 | 2015-02-26 | 住友化学株式会社 | 網膜組織及び網膜関連細胞の製造方法 |
| WO2015087231A1 (en) | 2013-12-11 | 2015-06-18 | Pfizer Limited | Method for producing retinal pigment epithelial cells |
| SG11201703305SA (en) | 2014-10-24 | 2017-05-30 | Sumitomo Dainippon Pharma Co Ltd | Production method for nerve tissue |
| KR102511192B1 (ko) | 2014-10-24 | 2023-03-17 | 스미토모 파마 가부시키가이샤 | 망막 조직의 제조 방법 |
| WO2016097183A1 (en) | 2014-12-18 | 2016-06-23 | Universite Pierre Et Marie Curie (Paris 6) | Transgenic rpe cells overexpressing otx2 for the treatment of retinal degeneration |
| IL273405B2 (en) | 2014-12-30 | 2024-01-01 | Cell Cure Neurosciences Ltd | Rpe cell populations and methods of generating same |
| IL253244B2 (en) * | 2014-12-30 | 2023-09-01 | Cell Cure Neurosciences Ltd | Methods for treating retinal diseases |
| SG10201907918VA (en) | 2015-03-23 | 2019-10-30 | Astellas Inst For Regenerative Medicine | Improved assays for potency of human retinal pigment epithelium (rpe) cells and photoreceptor progenitors |
| KR102651291B1 (ko) * | 2015-08-18 | 2024-03-26 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 임상 제제 |
| ES2971677T3 (es) | 2015-09-08 | 2024-06-06 | Sumitomo Pharma Co Ltd | Método para la producción de tejido retiniano |
| AU2016321170B2 (en) | 2015-09-08 | 2022-09-01 | Fujifilm Cellular Dynamics | Method for reproducible differentiation of clinical-grade retinal pigment epithelium cells |
| EP3347457B1 (en) * | 2015-09-08 | 2021-10-27 | FUJIFILM Cellular Dynamics, Inc. | Macs-based purification of stem cell-derived retinal pigment epithelium |
| US10947502B2 (en) | 2015-10-20 | 2021-03-16 | FUJIFILM Cellular Dynamics, Inc. | Methods for directed differentiation of pluripotent stem cells to immune cells |
| WO2017072763A1 (en) | 2015-10-26 | 2017-05-04 | Cell Cure Neurosciences Ltd. | Preparation of retinal pigment epithelium cells |
| JP6995314B2 (ja) | 2016-04-22 | 2022-02-21 | 大日本住友製薬株式会社 | 網膜組織の製造法 |
| CN109414457A (zh) * | 2016-06-30 | 2019-03-01 | 希里欧斯株式会社 | 移植用介质 |
| EP4467565A3 (en) | 2016-12-21 | 2025-03-12 | Amgen Inc. | Anti-tnf alpha antibody formulations |
| US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
| EP4083063A3 (en) | 2017-04-18 | 2023-01-04 | FUJIFILM Cellular Dynamics, Inc. | Antigen-specific immune effector cells |
| CA3075877A1 (en) | 2017-09-14 | 2019-03-21 | Riken | Method for producing retinal tissues |
| CN107760649B (zh) * | 2017-11-02 | 2021-03-30 | 北京全式金生物技术有限公司 | 一种用于人神经系统细胞培养和人多能性干细胞向神经系统细胞分化的营养添加剂 |
| KR102198942B1 (ko) * | 2019-07-02 | 2021-01-05 | 의료법인 성광의료재단 | Pedf를 발현하거나 모세포에 비하여 pedf를 과발현하도록 유전적으로 조작된 중간엽 줄기세포 |
| US20220260580A1 (en) * | 2019-07-19 | 2022-08-18 | Tokyo Electron Limited | Method for evaluating state of cell differentiation |
| KR20220106965A (ko) | 2019-10-30 | 2022-08-01 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | 망막 색소 상피 세포의 생성 방법 |
| WO2022191216A1 (ja) | 2021-03-09 | 2022-09-15 | 国立研究開発法人理化学研究所 | 低免疫原性網膜色素上皮細胞の製造方法 |
| CN118871141A (zh) | 2022-03-16 | 2024-10-29 | 住友制药株式会社 | 移植用介质 |
| CN119384700A (zh) | 2022-04-15 | 2025-01-28 | 艾斯本神经科学公司 | 细胞分化状态的分类方法和分化细胞的相关组合物 |
| JPWO2024172043A1 (cg-RX-API-DMAC7.html) | 2023-02-14 | 2024-08-22 | ||
| CN119020271B (zh) * | 2024-07-17 | 2025-06-06 | 中国农业大学 | 一种提高卵子体外成熟质量及体外受精后胚胎妊娠率的组合物、方法及其应用 |
Family Cites Families (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5610753A (en) | 1991-12-12 | 1997-03-11 | Eastman Kodak Company | Optical design of laser scanner to reduce thermal sensitivity |
| ATE196923T1 (de) | 1993-04-30 | 2000-10-15 | Photogenesis Inc | Transplantation des retinalen pigmentepithels |
| DE19609838A1 (de) | 1996-03-13 | 1997-09-18 | Boehringer Mannheim Gmbh | Verfahren und Teststreifen zur Bestimmung eines Analyten |
| US6878544B2 (en) | 1996-04-19 | 2005-04-12 | Neurotech Sa | Retinal cell lines with extended life-span and their applications |
| US20040086494A1 (en) | 1996-10-07 | 2004-05-06 | John Constance Mary | Immune privileged cells for delivery of proteins and peptides |
| AU5734998A (en) * | 1997-01-10 | 1998-08-03 | Life Technologies, Inc. | Embryonic stem cell serum replacement |
| US6331406B1 (en) | 1997-03-31 | 2001-12-18 | The John Hopkins University School Of Medicine | Human enbryonic germ cell and methods of use |
| WO1999012572A1 (en) | 1997-09-10 | 1999-03-18 | University Of Florida | Compounds and method for the prevention and treatment of diabetic retinopathy |
| CA2317115A1 (en) | 1998-01-02 | 1999-07-15 | Titan Pharmaceuticals, Inc. | Use of pigmented retinal epithelial cells for creation of an immune privilege site |
| EP1066368A4 (en) | 1998-03-02 | 2002-08-21 | Compucyte Corp | SELECTIVE CELL ANALYSIS |
| US6667176B1 (en) | 2000-01-11 | 2003-12-23 | Geron Corporation | cDNA libraries reflecting gene expression during growth and differentiation of human pluripotent stem cells |
| US6943153B1 (en) | 1999-03-15 | 2005-09-13 | The Regents Of The University Of California | Use of recombinant gene delivery vectors for treating or preventing diseases of the eye |
| US6331313B1 (en) | 1999-10-22 | 2001-12-18 | Oculex Pharmaceticals, Inc. | Controlled-release biocompatible ocular drug delivery implant devices and methods |
| AU782846B2 (en) | 1999-10-28 | 2005-09-01 | University Of Massachusetts | Gynogenetic or androgenetic production of pluripotent cells and cell lines, and use thereof to produce differentiated cells and tissues |
| JP2003533976A (ja) | 2000-01-07 | 2003-11-18 | オレゴン ヘルス アンド サイエンス ユニバーシティ | 胚分割による霊長類子孫のクローン性増殖 |
| US6602711B1 (en) | 2000-02-21 | 2003-08-05 | Wisconsin Alumni Research Foundation | Method of making embryoid bodies from primate embryonic stem cells |
| US20030084471A1 (en) | 2000-03-16 | 2003-05-01 | David Beach | Methods and compositions for RNA interference |
| US6458589B1 (en) | 2000-04-27 | 2002-10-01 | Geron Corporation | Hepatocyte lineage cells derived from pluripotent stem cells |
| CN1311081C (zh) | 2000-08-19 | 2007-04-18 | 爱克斯澳迪亚有限公司 | 干细胞分化 |
| US6576464B2 (en) | 2000-11-27 | 2003-06-10 | Geron Corporation | Methods for providing differentiated stem cells |
| ES2250504T3 (es) | 2000-11-29 | 2006-04-16 | Allergan Inc. | Prevencion del rechazo de injerto en el ojo. |
| DE10108412B4 (de) | 2001-02-21 | 2006-03-09 | Cevec Pharmaceuticals Gmbh | Pigmentepithelzelle des Auges, ihre Herstellung und Verwendung in der Therapie einer Augen- oder Nervenerkrankung |
| WO2002092756A2 (en) | 2001-05-15 | 2002-11-21 | Rappaport Family Institute For Research In The Medical Sciences | Insulin producing cells derived from human embryonic stem cells |
| US7425448B2 (en) | 2001-07-12 | 2008-09-16 | Geron Corporation | Cardiomyocyte precursors from human embryonic stem cells |
| CA2468292A1 (en) | 2001-11-26 | 2003-06-05 | Advanced Cell Technology, Inc. | Methods for making and using reprogrammed human somatic cell nuclei and autologous and isogenic human stem cells |
| JP4666567B2 (ja) | 2001-12-07 | 2011-04-06 | ジェロン・コーポレーション | ヒト胚幹細胞由来の膵島細胞 |
| WO2003049773A1 (en) | 2001-12-11 | 2003-06-19 | Fibrogen, Inc. | Methods for inhibiting ocular processes |
| CA2473909A1 (en) | 2002-01-15 | 2003-07-24 | Advanced Cell Technology, Inc. | Cloning b and t lymphocytes |
| EP1495120B1 (en) | 2002-04-18 | 2012-10-10 | Acuity Pharmaceuticals, Inc | Means and methods for the specific modulation of target genes in the eye |
| US20040091936A1 (en) | 2002-05-24 | 2004-05-13 | Michael West | Bank of stem cells for producing cells for transplantation having HLA antigens matching those of transplant recipients, and methods for making and using such a stem cell bank |
| US7422736B2 (en) * | 2002-07-26 | 2008-09-09 | Food Industry Research And Development Institute | Somatic pluripotent cells |
| US7824671B2 (en) | 2002-10-04 | 2010-11-02 | Tissuetech, Inc. | Retinal pigment epithelial cell cultures on amniotic membrane and transplantation |
| US20040133095A1 (en) | 2002-11-14 | 2004-07-08 | Dunki-Jacobs Robert J. | Methods and devices for detecting abnormal tissue cells |
| US20040156878A1 (en) | 2003-02-11 | 2004-08-12 | Alireza Rezania | Implantable medical device seeded with mammalian cells and methods of treatment |
| US20050032126A1 (en) | 2003-03-03 | 2005-02-10 | Coombs James H. | Methods and apparatus for use in detection and quantitation of various cell types and use of optical bio-disc for performing same |
| JP2006525006A (ja) | 2003-05-08 | 2006-11-09 | セルアーティス アーベー | 閉塞ストローガラス化方法を利用するヒト胚盤胞由来幹細胞の低温保存法 |
| KR100569168B1 (ko) | 2003-08-08 | 2006-04-07 | (주)아비코아생명공학연구소 | 조류 정원줄기세포의 배양방법 및 이에 의해 수득한 조류정원줄기세포 |
| US7794704B2 (en) | 2004-01-23 | 2010-09-14 | Advanced Cell Technology, Inc. | Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration |
| EP4248752A3 (en) | 2004-01-23 | 2024-01-03 | President And Fellows Of Harvard College | Improved modalities for the treatment of degenerative diseases of the retina |
| JP5138367B2 (ja) | 2004-05-07 | 2013-02-06 | ウイスコンシン アラムニ リサーチ ファンデーション | 胚性幹細胞から間葉性幹細胞を形成する方法 |
| US6945971B1 (en) | 2004-07-19 | 2005-09-20 | Gwon Arlene E | Controlled ocular lens regeneration |
| EP1799810A2 (en) | 2004-10-12 | 2007-06-27 | Technion Research & Development Foundation Ltd. | Isolated primate embryonic cells and methods of generating and using same |
| EP1812554A4 (en) | 2004-11-04 | 2008-10-08 | Advanced Cell Tech Inc | DERIVATION OF EMBRYONAL STEM CELLS |
| US7893315B2 (en) | 2004-11-04 | 2011-02-22 | Advanced Cell Technology, Inc. | Derivation of embryonic stem cells and embryo-derived cells |
| EP2048227B1 (en) | 2005-02-11 | 2015-08-19 | Agency For Science, Technology And Research | Methods for proliferating stem cells |
| RU2007146777A (ru) | 2005-05-17 | 2009-06-27 | Релайанс Лайф Сайенсиз Пвт Лтд (In) | Получение линии эмбриональных стволовых клеток человека с использованием клеток млекопитающих |
| EP1910548A4 (en) | 2005-05-27 | 2010-06-23 | Agency Science Tech & Res | METHOD OF INTRODUCING NUCLEIC ACID MOLECULES IN EMBRYONIC STEM CELLS USING BACULUS VIRUSORS |
| EP1909565A2 (en) | 2005-08-03 | 2008-04-16 | Interface Multigrad Technology (IMT) Ltd. | Somatic cells for use in cell therapy |
| JP4926615B2 (ja) | 2006-08-29 | 2012-05-09 | 太陽化学株式会社 | ガラクトマンナン酵素分解物の製造方法 |
| KR100832592B1 (ko) | 2006-08-17 | 2008-05-27 | 박현숙 | 폴리머 막을 이용한 줄기세포와 피더세포의 공배양방법 |
| ZA200901914B (en) | 2006-09-22 | 2010-06-30 | Riken | Stem cell culture medium and method |
| WO2008129554A1 (en) * | 2007-04-18 | 2008-10-30 | Hadasit Medical Research Services & Development Limited | Stem cell-derived retinal pigment epithelial cells |
| JP2008307007A (ja) | 2007-06-15 | 2008-12-25 | Bayer Schering Pharma Ag | 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞 |
| KR101849329B1 (ko) | 2007-10-12 | 2018-04-16 | 아스텔라스 인스티튜트 포 리제너러티브 메디슨 | Ｒｐｅ 세포의 개선된 생산 방법 및 ｒｐｅ 세포의 조성물 |
| HU0700675D0 (en) | 2007-10-15 | 2007-12-28 | Mta Tamogatott Kutatohelyek Ir | Method for monitoring stem cell differentiation |
| US20090226955A1 (en) | 2007-12-21 | 2009-09-10 | University Of Miami | Immortalized retinal pigmented epithelial cells |
| US20090233324A1 (en) | 2008-03-11 | 2009-09-17 | Kopf-Sill Anne R | Methods for Diagnosing Cancer Using Samples Collected From A Central Vein Location or an Arterial Location |
| WO2009132156A1 (en) * | 2008-04-22 | 2009-10-29 | Regenerative Research Foundation | Retinal pigment epithelial stem cells |
| US8652123B2 (en) | 2008-09-02 | 2014-02-18 | Geoffrey C. GURTNER | Methods and devices for improving the appearance of tissue |
| US10485829B2 (en) | 2009-11-17 | 2019-11-26 | Astellas Institute For Regenerative Medicine | Methods of producing human RPE cells and pharmaceutical preparations of human RPE cells |
| HUE054517T2 (hu) | 2010-07-23 | 2021-09-28 | Astellas Inst For Regenerative Medicine | Eljárások sejtek ritka alpopulációinak detektálására és nagymértékben tisztított sejtkészítmények |
| JP6200883B2 (ja) | 2011-04-29 | 2017-09-20 | ユニヴァーシティー オブ サザン カリフォルニア | ポリマー基質上の幹細胞由来網膜色素上皮細胞の低温保存方法 |
| IL320536A (en) | 2011-11-14 | 2025-06-01 | Astellas Inst For Regenerative Medicine | Pharmaceutical preparations of human RPE cells and their use |
| US9850463B2 (en) | 2012-02-01 | 2017-12-26 | The Regents Of The University Of California | Methods of culturing retinal pigmented epithelium cells, including xeno-free production, RPE enrichment, and cryopreservation |
| US9458428B2 (en) | 2012-06-05 | 2016-10-04 | The Regents Of The University Of California | Methods and compositions for the rapid production of retinal pigmented epithelial cells from pluripotent cells |
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