JP2022058682A5 - - Google Patents
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- JP2022058682A5 JP2022058682A5 JP2022007043A JP2022007043A JP2022058682A5 JP 2022058682 A5 JP2022058682 A5 JP 2022058682A5 JP 2022007043 A JP2022007043 A JP 2022007043A JP 2022007043 A JP2022007043 A JP 2022007043A JP 2022058682 A5 JP2022058682 A5 JP 2022058682A5
- Authority
- JP
- Japan
- Prior art keywords
- synergistic combination
- gram
- composition
- amino acid
- antibiotics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261644944P | 2012-05-09 | 2012-05-09 | |
| US61/644,944 | 2012-05-09 | ||
| US201261737239P | 2012-12-14 | 2012-12-14 | |
| US61/737,239 | 2012-12-14 | ||
| JP2019221319A JP2020054370A (ja) | 2012-05-09 | 2019-12-06 | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019221319A Division JP2020054370A (ja) | 2012-05-09 | 2019-12-06 | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022058682A JP2022058682A (ja) | 2022-04-12 |
| JP2022058682A5 true JP2022058682A5 (enExample) | 2023-01-04 |
Family
ID=49551273
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015511698A Expired - Fee Related JP6608697B2 (ja) | 2012-05-09 | 2013-05-09 | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
| JP2018086685A Withdrawn JP2018138045A (ja) | 2012-05-09 | 2018-04-27 | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
| JP2019221319A Pending JP2020054370A (ja) | 2012-05-09 | 2019-12-06 | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
| JP2022007043A Pending JP2022058682A (ja) | 2012-05-09 | 2022-01-20 | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015511698A Expired - Fee Related JP6608697B2 (ja) | 2012-05-09 | 2013-05-09 | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
| JP2018086685A Withdrawn JP2018138045A (ja) | 2012-05-09 | 2018-04-27 | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
| JP2019221319A Pending JP2020054370A (ja) | 2012-05-09 | 2019-12-06 | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
Country Status (16)
| Country | Link |
|---|---|
| US (5) | US10813983B2 (enExample) |
| EP (2) | EP3685851A1 (enExample) |
| JP (4) | JP6608697B2 (enExample) |
| KR (3) | KR20210121313A (enExample) |
| CN (1) | CN104736172A (enExample) |
| AU (3) | AU2013259512B2 (enExample) |
| BR (1) | BR112014027842A2 (enExample) |
| CA (1) | CA2872902A1 (enExample) |
| DK (1) | DK2849782T3 (enExample) |
| ES (1) | ES2784136T3 (enExample) |
| HK (1) | HK1211484A1 (enExample) |
| IL (3) | IL308477A (enExample) |
| IN (1) | IN2014MN02437A (enExample) |
| MX (2) | MX389127B (enExample) |
| RU (2) | RU2018121290A (enExample) |
| WO (1) | WO2013170015A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6608697B2 (ja) | 2012-05-09 | 2019-11-20 | コントラフェクト コーポレイション | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
| RU2646102C2 (ru) | 2012-05-09 | 2018-03-01 | Контрафект Корпорейшн | Предотвращение, разрушение и обработка биопленки лизином бактериофага |
| EP3164146B1 (en) * | 2014-06-26 | 2019-12-25 | The Rockefeller University | Acinetobacter lysins |
| EP3268023B1 (en) * | 2015-03-12 | 2021-08-18 | Micreos Human Health B.V. | Combination of bactericidal agent with a lysosomotropic alkalinising agent for the treatment of a bacterial infection |
| EP3349781A2 (en) | 2015-09-17 | 2018-07-25 | Contrafect Corporation | Use of lysin to restore/augment antibacterial activity in the presence of pulmonary surfactant of antibiotics inhibited thereby |
| DK3454888T3 (da) | 2016-05-12 | 2021-04-26 | Contrafect Corp | Bouillon-mikrofortyndingsfremgangsmåde til evaluering og bestemmelse af minimal inhibitorisk koncentration for antibakterielle polypeptider |
| DK3641753T3 (da) * | 2017-06-19 | 2022-12-12 | Univ Syddansk | Bacitracin og/eller daptomycin kombineret med cannabidiol til behandling af bakterieinfektioner |
| US20220023399A1 (en) * | 2017-07-10 | 2022-01-27 | Contrafect Corporation | Blood component potentiation of lytic protein anti-bacterial activity and methods and uses thereof |
| MX2020008860A (es) * | 2018-02-26 | 2020-12-10 | Contrafect Corp | Lisinas plyss2 modificadas y sus usos. |
| CN116850269A (zh) * | 2018-06-22 | 2023-10-10 | 康特拉费克特公司 | 溶素及其衍生物使金黄色葡萄球菌和革兰氏阳性菌对抗生素重新敏感 |
| CN109668873B (zh) * | 2018-12-05 | 2021-03-16 | 山东恒业生物技术有限公司 | 一种活载体疫苗活性检测装置及其使用方法 |
| AU2020218330B2 (en) * | 2019-02-05 | 2023-10-12 | Biomedit, Llc | Probiotic compositions comprising lactobacillus reuteri strains and methods of use |
| CA3134154A1 (en) * | 2019-03-22 | 2020-10-01 | Contrafect Corporation | Method of treating infective endocarditis |
| JP2022526624A (ja) * | 2019-04-11 | 2022-05-25 | コントラフェクト コーポレイション | 骨及び関節の感染を治療及び予防する方法 |
| WO2021127452A1 (en) * | 2019-12-19 | 2021-06-24 | Georgia State University Research Foundation, Inc. | Compounds for the treatment of bacterial infections and potentiation of antibiotics |
| IL297953A (en) * | 2020-05-19 | 2023-01-01 | Contrafect Corp | Modified plyss2 lysines and antibiotic combinations for use against gram-positive bacteria |
| RU2755817C1 (ru) * | 2020-07-22 | 2021-09-21 | Федеральное Государственное бюджетное научное учреждение "Федеральный научный центр биологических систем и агротехнологий российской академии наук" | Способ снижения грамположительной микрофлоры в кишечнике птицы |
| KR102528412B1 (ko) * | 2020-09-08 | 2023-05-04 | 클립스비엔씨 주식회사 | 신규한 포도상구균 감염 질환의 예방 또는 치료용 조성물 |
| WO2022261360A1 (en) * | 2021-06-09 | 2022-12-15 | Contrafect Corporation | Plyss2 lysins and variants thereof for use against multidrug resistant gram-positive bacteria |
| CN115105491B (zh) * | 2022-07-08 | 2023-12-22 | 东北农业大学 | 丝氨酸在制备抑制猪链球菌药物中的用途 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU8108587A (en) | 1986-10-08 | 1988-05-06 | David Bernstein | Method for exposing group a streptococcal antigens and an improved diagnostic test for the identification of group a streptococci |
| ZA883887B (en) | 1987-06-10 | 1990-02-28 | Lilly Co Eli | Chromatographic purification process |
| EP0895534A1 (en) * | 1996-04-15 | 1999-02-10 | Nymox Corporation | Compositions containing bacteriophages and methods of using bacteriophages to treat infections |
| US6254866B1 (en) | 1997-10-31 | 2001-07-03 | New Horizons Diagnostics Corporation | Use of phage associated lytic enzymes for treating bacterial infections of the digestive tract |
| US5997862A (en) | 1997-10-31 | 1999-12-07 | New Horizons Diagnostics Corporation | Therapeutic treatment of group A streptococcal infections |
| US20060292135A1 (en) | 1997-10-31 | 2006-12-28 | Lawrence Loomis | Use of bacterial phage-associated lysing proteins for preventing and treating bacterial infections in humans, animals and fowl |
| US6264945B1 (en) | 1997-10-31 | 2001-07-24 | Vincent A Fischetti | Parenteral use of bacterial phage associated lysing enzymes for the therapeutic treatment of bacterial infections |
| US6248324B1 (en) | 1997-10-31 | 2001-06-19 | Vincent Fischetti | Bacterial phage associated lysing enzymes for treating dermatological infections |
| HK1047243A1 (zh) | 1999-02-25 | 2003-02-14 | 新眼界诊断公司 | 預防性和治療性治療鏈球菌感染的方法 |
| US6056955A (en) | 1999-09-14 | 2000-05-02 | Fischetti; Vincent | Topical treatment of streptococcal infections |
| US6444813B2 (en) | 2000-02-02 | 2002-09-03 | Pharmacia & Upjohn Company | Linezolid-crystal form II |
| AU2003291614A1 (en) | 2002-05-17 | 2004-04-08 | New Horizons Diagnostics Corporation | Identification of a phage associated lytic enzyme to rapidly and specifically detect and kill bacillus anthracis |
| US7569223B2 (en) | 2004-03-22 | 2009-08-04 | The Rockefeller University | Phage-associated lytic enzymes for treatment of Streptococcus pneumoniae and related conditions |
| EP1744779A2 (en) * | 2004-03-24 | 2007-01-24 | The Rockfeller University | Lytic enzymes and spore surface antigen for detection and treatment of "bacillus anthracis" bacteria and spores |
| US8389469B2 (en) | 2005-06-06 | 2013-03-05 | The Rockefeller University | Bacteriophage lysins for Bacillus anthracis |
| US7582291B2 (en) | 2005-06-30 | 2009-09-01 | The Rockefeller University | Bacteriophage lysins for Enterococcus faecalis, Enterococcus faecium and other bacteria |
| EP2360248A1 (en) | 2005-08-24 | 2011-08-24 | The Rockefeller University | Ply-GBS mutant lysins |
| US20090053149A1 (en) | 2007-08-24 | 2009-02-26 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Surfactant-based antimicrobial solution for inhalation |
| CA2729160C (en) | 2008-07-03 | 2017-11-14 | The Rockefeller University | A chimeric bacteriophage lysin with activity against staphylococci bacteria |
| KR101016918B1 (ko) | 2009-01-08 | 2011-02-25 | 주식회사 인트론바이오테크놀로지 | 박테리아 특이적 넓은 항균 활성을 갖는 신규한 리신 단백질 |
| CN103080307A (zh) | 2010-01-25 | 2013-05-01 | 美艾利尔斯卡保罗有限公司 | A25噬菌体溶解酶 |
| WO2012145530A2 (en) * | 2011-04-20 | 2012-10-26 | Visa International Service Association | Managing electronic tokens in a transaction processing system |
| US20140179594A1 (en) | 2011-04-21 | 2014-06-26 | The Rockefeller University | Streptococcus bacteriophage lysins for treatment of gram positive bacteria in companion animals and livestock |
| CA2833409A1 (en) * | 2011-04-21 | 2012-10-26 | The Rockefeller University | Streptococcus bacteriophage lysins for detection and treatment of gram positive bacteria |
| WO2012145693A1 (en) | 2011-04-22 | 2012-10-26 | Rks Design, Inc. | Instrument retention assembly |
| EP2993181A1 (en) | 2011-04-27 | 2016-03-09 | Lysando AG | New antimicrobial agents |
| JP6608697B2 (ja) | 2012-05-09 | 2019-11-20 | コントラフェクト コーポレイション | グラム陽性菌に対するバクテリオファージ溶解素と抗生物質との組み合わせ |
| RU2646102C2 (ru) | 2012-05-09 | 2018-03-01 | Контрафект Корпорейшн | Предотвращение, разрушение и обработка биопленки лизином бактериофага |
-
2013
- 2013-05-09 JP JP2015511698A patent/JP6608697B2/ja not_active Expired - Fee Related
- 2013-05-09 BR BR112014027842A patent/BR112014027842A2/pt not_active IP Right Cessation
- 2013-05-09 US US14/399,575 patent/US10813983B2/en not_active Expired - Fee Related
- 2013-05-09 ES ES13787128T patent/ES2784136T3/es active Active
- 2013-05-09 CA CA2872902A patent/CA2872902A1/en active Pending
- 2013-05-09 IL IL308477A patent/IL308477A/en unknown
- 2013-05-09 KR KR1020217031525A patent/KR20210121313A/ko not_active Ceased
- 2013-05-09 IN IN2437MUN2014 patent/IN2014MN02437A/en unknown
- 2013-05-09 HK HK15112347.8A patent/HK1211484A1/xx unknown
- 2013-05-09 EP EP20158873.8A patent/EP3685851A1/en active Pending
- 2013-05-09 WO PCT/US2013/040329 patent/WO2013170015A1/en not_active Ceased
- 2013-05-09 RU RU2018121290A patent/RU2018121290A/ru unknown
- 2013-05-09 EP EP13787128.1A patent/EP2849782B1/en active Active
- 2013-05-09 KR KR1020147034614A patent/KR102310387B1/ko not_active Expired - Fee Related
- 2013-05-09 RU RU2014149351A patent/RU2659208C2/ru active
- 2013-05-09 IL IL235527A patent/IL235527B2/en unknown
- 2013-05-09 AU AU2013259512A patent/AU2013259512B2/en not_active Ceased
- 2013-05-09 DK DK13787128.1T patent/DK2849782T3/da active
- 2013-05-09 MX MX2014013586A patent/MX389127B/es unknown
- 2013-05-09 CN CN201380036510.8A patent/CN104736172A/zh active Pending
- 2013-05-09 KR KR1020237023634A patent/KR20230113404A/ko not_active Withdrawn
- 2013-06-04 US US13/909,618 patent/US9889181B2/en active Active
-
2014
- 2014-11-07 MX MX2021011843A patent/MX2021011843A/es unknown
-
2017
- 2017-12-20 US US15/848,886 patent/US20180221456A1/en not_active Abandoned
-
2018
- 2018-04-24 AU AU2018202845A patent/AU2018202845B2/en not_active Ceased
- 2018-04-27 JP JP2018086685A patent/JP2018138045A/ja not_active Withdrawn
-
2019
- 2019-12-06 JP JP2019221319A patent/JP2020054370A/ja active Pending
-
2020
- 2020-05-21 IL IL274832A patent/IL274832A/en unknown
- 2020-09-16 AU AU2020233683A patent/AU2020233683A1/en not_active Abandoned
- 2020-09-25 US US17/033,195 patent/US20210008175A1/en not_active Abandoned
-
2021
- 2021-01-05 US US17/141,692 patent/US20210128696A1/en not_active Abandoned
-
2022
- 2022-01-20 JP JP2022007043A patent/JP2022058682A/ja active Pending
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