WO2010131865A3 - 항생제 내성 균주에 대한 항균용 조성물 - Google Patents

항생제 내성 균주에 대한 항균용 조성물 Download PDF

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Publication number
WO2010131865A3
WO2010131865A3 PCT/KR2010/002845 KR2010002845W WO2010131865A3 WO 2010131865 A3 WO2010131865 A3 WO 2010131865A3 KR 2010002845 W KR2010002845 W KR 2010002845W WO 2010131865 A3 WO2010131865 A3 WO 2010131865A3
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WO
WIPO (PCT)
Prior art keywords
antibiotic
resistant
antimicrobial composition
resistant strain
present
Prior art date
Application number
PCT/KR2010/002845
Other languages
English (en)
French (fr)
Other versions
WO2010131865A2 (ko
Inventor
김종기
김헌
임수연
이수성
Original Assignee
중앙대학교 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020090041743A external-priority patent/KR20100122713A/ko
Priority claimed from KR1020090041757A external-priority patent/KR101171871B1/ko
Application filed by 중앙대학교 산학협력단 filed Critical 중앙대학교 산학협력단
Publication of WO2010131865A2 publication Critical patent/WO2010131865A2/ko
Publication of WO2010131865A3 publication Critical patent/WO2010131865A3/ko

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/26—Cyanate or isocyanate esters; Thiocyanate or isothiocyanate esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

본 발명은 설포라펜 및 설포라판으로 이루어진 군에서 하나 이상 선택된 것을 유효성분으로 포함하는 항생제 내성 균주에 대한 항균용 조성물에 관한 것으로, 보다 구체적으로 메티실린 저항성 포도상구균, 반코마이신 저항성 장구균 또는 항생제 내성을 가지는 대장균, 폐렴간균, 살모넬라 티피뮤리움 및 엔테로코커스 패칼리스 등에 작용하여 항생제 내성 균주의 생장을 억제시킬 수 있는 설포라펜 및 설포라판으로 이루어진 군에서 하나 이상 선택된 것을 유효성분으로 포함하는 항균용 조성물에 관한 것이다. 본 발명의 항균용 조성물은 반코마이신, 페니실린 또는 메티실린 등의 베타락탐 계열 또는 비-베타락탐 계열 항생제에 대하여 내성을 가지는 그람음성균 및 그람양성균의 생장을 억제함으로써, 항생제 내성 박테리아의 감염으로 인하여 발생하는 각종 감염질환의 예방 및 치료용으로 사용할 수 있으며, 슈퍼박테리아 항생제로서 유용하게 사용될 수 있다.
PCT/KR2010/002845 2009-05-13 2010-05-04 항생제 내성 균주에 대한 항균용 조성물 WO2010131865A2 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2009-0041743 2009-05-13
KR10-2009-0041757 2009-05-13
KR1020090041743A KR20100122713A (ko) 2009-05-13 2009-05-13 설포라판을 유효성분으로 포함하는 항생제 내성 균주에 대한 항균용 조성물
KR1020090041757A KR101171871B1 (ko) 2009-05-13 2009-05-13 설포라펜을 유효성분으로 포함하는 항생제 내성 균주에 대한 항균용 조성물

Publications (2)

Publication Number Publication Date
WO2010131865A2 WO2010131865A2 (ko) 2010-11-18
WO2010131865A3 true WO2010131865A3 (ko) 2011-03-24

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2010/002845 WO2010131865A2 (ko) 2009-05-13 2010-05-04 항생제 내성 균주에 대한 항균용 조성물

Country Status (1)

Country Link
WO (1) WO2010131865A2 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111956651A (zh) * 2020-08-19 2020-11-20 陈洪亮 一种新型抗生素
CN115066416A (zh) * 2020-08-20 2022-09-16 普洱祺云生物科技有限公司 富含萝卜硫素的提取物的制备方法及用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000086414A (ja) * 1998-09-04 2000-03-28 Kinjirushi Wasabi Kk 制菌、抗菌性に優れた抗菌剤

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000086414A (ja) * 1998-09-04 2000-03-28 Kinjirushi Wasabi Kk 制菌、抗菌性に優れた抗菌剤

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JED W. FAHEY ET AL.: "Sulforaphane inhibits extracellular, intracellular, and antibiotic- resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors", PNAS, vol. 99, no. 11, 28 May 2002 (2002-05-28), pages 7610 - 7615 *
NOELLE L JOHANSSON ET AL.: "Growth inhibition of a spectrum of bacterial and fungal pathogens by sulforaphane, an isothiocyanate product found in broccoli and other cruciferous vegetables", PLANTA MEDICA, vol. 74, no. 7, 2008, pages 747 - 750 *

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Publication number Publication date
WO2010131865A2 (ko) 2010-11-18

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