DK3454888T3 - Bouillon-mikrofortyndingsfremgangsmåde til evaluering og bestemmelse af minimal inhibitorisk koncentration for antibakterielle polypeptider - Google Patents

Bouillon-mikrofortyndingsfremgangsmåde til evaluering og bestemmelse af minimal inhibitorisk koncentration for antibakterielle polypeptider Download PDF

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Publication number
DK3454888T3
DK3454888T3 DK17796910.2T DK17796910T DK3454888T3 DK 3454888 T3 DK3454888 T3 DK 3454888T3 DK 17796910 T DK17796910 T DK 17796910T DK 3454888 T3 DK3454888 T3 DK 3454888T3
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Denmark
Prior art keywords
evaluation
determination
inhibitory concentration
minimal inhibitory
broth microdilution
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Application number
DK17796910.2T
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English (en)
Inventor
Raymond Schuch
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Contrafect Corp
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Publication of DK3454888T3 publication Critical patent/DK3454888T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18Testing for antimicrobial activity of a material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y302/00Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01017Lysozyme (3.2.1.17)

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK17796910.2T 2016-05-12 2017-05-12 Bouillon-mikrofortyndingsfremgangsmåde til evaluering og bestemmelse af minimal inhibitorisk koncentration for antibakterielle polypeptider DK3454888T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662335129P 2016-05-12 2016-05-12
PCT/US2017/032344 WO2017197227A1 (en) 2016-05-12 2017-05-12 Broth microdilution method for evaluating and determining minimal inhibitory concentration of antibacterial polypeptides

Publications (1)

Publication Number Publication Date
DK3454888T3 true DK3454888T3 (da) 2021-04-26

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ID=60266856

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17796910.2T DK3454888T3 (da) 2016-05-12 2017-05-12 Bouillon-mikrofortyndingsfremgangsmåde til evaluering og bestemmelse af minimal inhibitorisk koncentration for antibakterielle polypeptider

Country Status (14)

Country Link
US (1) US10851401B2 (da)
EP (1) EP3454888B1 (da)
JP (1) JP6875756B2 (da)
KR (1) KR20190004799A (da)
CN (1) CN109152822B (da)
AU (1) AU2017263563A1 (da)
BR (1) BR112018073205A2 (da)
CA (1) CA3023730A1 (da)
DK (1) DK3454888T3 (da)
IL (1) IL262844B2 (da)
MX (1) MX2018013372A (da)
RU (1) RU2754667C2 (da)
WO (1) WO2017197227A1 (da)
ZA (1) ZA201806685B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102441211B1 (ko) * 2014-06-26 2022-09-07 더 락커펠러 유니버시티 아시네토박터 라이신
EP3758738A4 (en) * 2018-02-26 2021-12-08 Contrafect Corporation MODIFIED PLYSS2-LYSINE AND USES THEREOF
US11649477B2 (en) 2018-07-11 2023-05-16 SeLux Diagnostics, Inc. Assays and reagents for antimicrobial susceptibility testing
JP2022525914A (ja) * 2019-03-22 2022-05-20 コントラフェクト コーポレイション 感染性心内膜炎を治療する方法
MX2021012375A (es) * 2019-04-11 2021-11-17 Contrafect Corp Metodo para tratar y prevenir infecciones oseas y de articulaciones.

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0285649A4 (en) 1986-10-08 1990-06-27 David Bernstein METHOD FOR EXPOSING ANTIGENS OF GROUP A STREPTOCOCCUS AND IMPROVED DIAGNOSTIC TEST FOR THE IDENTIFICATION OF GROUP A STREPTOCOCCUS
US6254866B1 (en) 1997-10-31 2001-07-03 New Horizons Diagnostics Corporation Use of phage associated lytic enzymes for treating bacterial infections of the digestive tract
US6264945B1 (en) 1997-10-31 2001-07-24 Vincent A Fischetti Parenteral use of bacterial phage associated lysing enzymes for the therapeutic treatment of bacterial infections
US5997862A (en) 1997-10-31 1999-12-07 New Horizons Diagnostics Corporation Therapeutic treatment of group A streptococcal infections
US6248324B1 (en) 1997-10-31 2001-06-19 Vincent Fischetti Bacterial phage associated lysing enzymes for treating dermatological infections
JP2002537350A (ja) 1999-02-25 2002-11-05 ニュー ホライズンズ ダイアグノスティックス インコーポレーティッド 連鎖球菌感染の予防的及び治療的な処置のための手段
US6056955A (en) 1999-09-14 2000-05-02 Fischetti; Vincent Topical treatment of streptococcal infections
JP4381531B2 (ja) * 1999-12-08 2009-12-09 塩野義製薬株式会社 グリコペプチド誘導体
EP1501925A4 (en) 2002-05-17 2006-10-25 New Horizons Diagnostics Corp IDENTIFICATION OF A PHAGEN-ASSOCIATED LYTICAL ENZYME FOR THE FAST AND SPECIFIC DETECTION AND BUTTERFLY OF BACILLUS ANTHRACIS
US7569223B2 (en) 2004-03-22 2009-08-04 The Rockefeller University Phage-associated lytic enzymes for treatment of Streptococcus pneumoniae and related conditions
US7638600B2 (en) 2004-03-24 2009-12-29 The Rockefeller University Lytic enzymes and spore surface antigen for detection and treatment of Bacillus anthracis bacteria and spores
WO2008018854A2 (en) 2005-06-06 2008-02-14 The Rockefeller University Bactiophage lysins for bacillus anthracis
US7582291B2 (en) 2005-06-30 2009-09-01 The Rockefeller University Bacteriophage lysins for Enterococcus faecalis, Enterococcus faecium and other bacteria
DE602006018746D1 (de) 2005-08-24 2011-01-20 Univ Rockefeller Ply-gbs-lysinmutanten
EP3263588A1 (en) 2008-07-03 2018-01-03 The Rockefeller University Isolated staphylococcus-specific soluble binding molecule
CA2799572C (en) * 2010-05-25 2018-12-11 Genome Pharmaceuticals Institute Co., Ltd. Novel cyclic peptide compound, method for producing same, anti-infective agent, antibiotic-containing fraction, antibiotic, method for producing antibiotic, antibiotic-producing microorganism, and antibiotic produced by same
JP5823733B2 (ja) * 2010-05-25 2015-11-25 株式会社ゲノム創薬研究所 抗生物質産生微生物及びそれが産生した抗生物質
ES2682670T3 (es) 2011-04-21 2018-09-21 The Rockefeller University Lisinas de bacteriófagos de Streptococcus para la detección y tratamiento de bacterias gram positivas
US10813983B2 (en) * 2012-05-09 2020-10-27 Contrafect Corporation Bacteriophage lysin and antibiotic combinations against gram positive bacteria

Also Published As

Publication number Publication date
KR20190004799A (ko) 2019-01-14
IL262844B2 (en) 2023-07-01
IL262844B1 (en) 2023-03-01
RU2018135238A3 (da) 2020-09-11
EP3454888A4 (en) 2019-12-11
ZA201806685B (en) 2021-02-24
CN109152822A (zh) 2019-01-04
BR112018073205A2 (pt) 2019-02-19
EP3454888B1 (en) 2021-02-24
CA3023730A1 (en) 2017-11-16
JP6875756B2 (ja) 2021-05-26
CN109152822B (zh) 2023-12-05
EP3454888A1 (en) 2019-03-20
RU2018135238A (ru) 2020-06-15
WO2017197227A1 (en) 2017-11-16
JP2019514439A (ja) 2019-06-06
IL262844A (en) 2018-12-31
MX2018013372A (es) 2019-05-09
RU2754667C2 (ru) 2021-09-06
US10851401B2 (en) 2020-12-01
AU2017263563A1 (en) 2018-10-18
US20190106724A1 (en) 2019-04-11

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