DE602006018746D1 - Ply-gbs-lysinmutanten - Google Patents

Ply-gbs-lysinmutanten

Info

Publication number
DE602006018746D1
DE602006018746D1 DE602006018746T DE602006018746T DE602006018746D1 DE 602006018746 D1 DE602006018746 D1 DE 602006018746D1 DE 602006018746 T DE602006018746 T DE 602006018746T DE 602006018746 T DE602006018746 T DE 602006018746T DE 602006018746 D1 DE602006018746 D1 DE 602006018746D1
Authority
DE
Germany
Prior art keywords
gbs
plygbs
streptococci
lysins
bacteria
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006018746T
Other languages
English (en)
Inventor
Vincent A Fischetti
Qi Cheng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rockefeller University
Original Assignee
Rockefeller University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rockefeller University filed Critical Rockefeller University
Publication of DE602006018746D1 publication Critical patent/DE602006018746D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE602006018746T 2005-08-24 2006-08-17 Ply-gbs-lysinmutanten Active DE602006018746D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US71093605P 2005-08-24 2005-08-24
PCT/US2006/032176 WO2007024628A2 (en) 2005-08-24 2006-08-17 Ply-gbs mutant lysins

Publications (1)

Publication Number Publication Date
DE602006018746D1 true DE602006018746D1 (de) 2011-01-20

Family

ID=37772174

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006018746T Active DE602006018746D1 (de) 2005-08-24 2006-08-17 Ply-gbs-lysinmutanten

Country Status (9)

Country Link
US (1) US8105585B2 (de)
EP (2) EP1917355B1 (de)
JP (1) JP2009506033A (de)
CN (1) CN101297034A (de)
AT (1) ATE491026T1 (de)
CA (1) CA2620903A1 (de)
DE (1) DE602006018746D1 (de)
ES (1) ES2357626T3 (de)
WO (1) WO2007024628A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008018854A2 (en) * 2005-06-06 2008-02-14 The Rockefeller University Bactiophage lysins for bacillus anthracis
DE602006018746D1 (de) 2005-08-24 2011-01-20 Univ Rockefeller Ply-gbs-lysinmutanten
EP3263588A1 (de) * 2008-07-03 2018-01-03 The Rockefeller University Molécule isolée soluble se liant spécifiquement à staphylococcus
ES2682670T3 (es) 2011-04-21 2018-09-21 The Rockefeller University Lisinas de bacteriófagos de Streptococcus para la detección y tratamiento de bacterias gram positivas
CN104114695B (zh) 2011-10-05 2018-04-17 洛克菲勒大学 二聚噬菌体溶素
CN102516398B (zh) * 2011-12-27 2014-07-16 中国科学院遗传与发育生物学研究所 抗乳房炎转基因小鼠模型的构建方法及其专用载体
US10813983B2 (en) 2012-05-09 2020-10-27 Contrafect Corporation Bacteriophage lysin and antibiotic combinations against gram positive bacteria
US9499594B2 (en) 2012-05-09 2016-11-22 Contrafect Corporation Biofilm prevention, disruption and treatment with bacteriophage lysin
DE102013106455A1 (de) 2013-06-20 2014-12-24 Airbus Defence and Space GmbH Verfahren zur Dekontamination von bakteriologischen Verunreinigungen
AU2017263563A1 (en) 2016-05-12 2018-10-18 Contrafect Corporation Broth microdilution method for evaluating and determining minimal inhibitory concentration of antibacterial polypeptides
CN107083434B (zh) * 2017-06-05 2020-09-08 武汉赛思锐微生物技术有限公司 一种非诊断目的的荧光pcr定量检测b族链球菌的样本前处理方法
EA202090748A1 (ru) * 2017-06-16 2020-08-11 Борис Славинович ФАРБЕР Биологически активные комбинаторные производные полисахаридов
EP3771463A1 (de) * 2019-07-29 2021-02-03 Ludwig-Maximilians-Universität München Stabilisierung therapeutischer proteine mit piperazin- oder morpholinhaltigen zwitterionischen puffersubstanzen
CN112501189A (zh) * 2020-12-30 2021-03-16 吉林大学 一种能杀死马链球菌马亚种的裂解酶及其医用用途
KR20240015756A (ko) * 2022-07-26 2024-02-06 주식회사 인트론바이오테크놀로지 젖소유방염 치료용 항균단백질 조성물

Family Cites Families (31)

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US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
JPS6023084B2 (ja) 1979-07-11 1985-06-05 味の素株式会社 代用血液
US4640835A (en) 1981-10-30 1987-02-03 Nippon Chemiphar Company, Ltd. Plasminogen activator derivatives
WO1985002092A1 (en) 1983-11-14 1985-05-23 Bio-Mimetics Inc. Bioadhesive compositions and methods of treatment therewith
US4496689A (en) * 1983-12-27 1985-01-29 Miles Laboratories, Inc. Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
GB2183661B (en) * 1985-03-30 1989-06-28 Marc Ballivet Method for obtaining dna, rna, peptides, polypeptides or proteins by means of a dna recombinant technique
EP0206448B1 (de) * 1985-06-19 1990-11-14 Ajinomoto Co., Inc. Hämoglobin, das an ein Poly(alkenylenoxid) gebunden ist
US4680338A (en) 1985-10-17 1987-07-14 Immunomedics, Inc. Bifunctional linker
EP0272253A4 (de) 1986-03-07 1990-02-05 Massachusetts Inst Technology Verfahren zur verbesserung der glykoproteinstabilität.
US4791192A (en) * 1986-06-26 1988-12-13 Takeda Chemical Industries, Ltd. Chemically modified protein with polyethyleneglycol
US4948580A (en) 1988-12-08 1990-08-14 E. R. Squibb & Sons, Inc. Muco-bioadhesive composition
US5225538A (en) 1989-02-23 1993-07-06 Genentech, Inc. Lymphocyte homing receptor/immunoglobulin fusion proteins
JPH02258718A (ja) 1989-03-31 1990-10-19 Nippon Kayaku Co Ltd ペースト状基剤及び製剤
US5264563A (en) * 1990-08-24 1993-11-23 Ixsys Inc. Process for synthesizing oligonucleotides with random codons
CA2150803C (en) * 1992-12-02 2006-01-31 Henry Auer Controlled release growth hormone containing microspheres
US5605793A (en) * 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
US5554380A (en) 1994-08-04 1996-09-10 Kv Pharmaceutical Company Bioadhesive pharmaceutical delivery system
AU695323B2 (en) 1994-09-09 1998-08-13 Takeda Chemical Industries Ltd. Sustained release preparation containing metal salt of a peptide
PT831787E (pt) 1995-06-07 2002-02-28 Alkermes Inc Composicao para libertacao sustentada da hormona de crescimento humano
ZA965368B (en) 1995-07-14 1997-01-14 Novo Nordisk As A pharmaceutical formulation
US5863560A (en) * 1996-09-11 1999-01-26 Virotex Corporation Compositions and methods for topical application of therapeutic agents
US5942243A (en) 1996-11-12 1999-08-24 Polytherapeutics, Inc. Mucoadhesive compositions for administration of biologically active agents to animal tissue
US6056954A (en) * 1997-10-31 2000-05-02 New Horizons Diagnostics Corp Use of bacterial phage associated lysing enzymers for the prophylactic and therapeutic treatment of various illnesses
US6056955A (en) * 1999-09-14 2000-05-02 Fischetti; Vincent Topical treatment of streptococcal infections
EP1501925A4 (de) * 2002-05-17 2006-10-25 New Horizons Diagnostics Corp Identifizierung eines phagenassoziierten lytischen enzyms zum schnellen und spezifischen nachweisen und abtöten von bacillus anthracis
EP1546175A4 (de) * 2002-08-29 2005-11-09 Uab Research Foundation Phagenlysin von gruppe-b-streptokokken
US7569223B2 (en) * 2004-03-22 2009-08-04 The Rockefeller University Phage-associated lytic enzymes for treatment of Streptococcus pneumoniae and related conditions
US7638600B2 (en) * 2004-03-24 2009-12-29 The Rockefeller University Lytic enzymes and spore surface antigen for detection and treatment of Bacillus anthracis bacteria and spores
US7582291B2 (en) * 2005-06-30 2009-09-01 The Rockefeller University Bacteriophage lysins for Enterococcus faecalis, Enterococcus faecium and other bacteria
DE602006018746D1 (de) 2005-08-24 2011-01-20 Univ Rockefeller Ply-gbs-lysinmutanten
EP3263588A1 (de) 2008-07-03 2018-01-03 The Rockefeller University Molécule isolée soluble se liant spécifiquement à staphylococcus

Also Published As

Publication number Publication date
EP2360248A1 (de) 2011-08-24
US20080221035A1 (en) 2008-09-11
WO2007024628A2 (en) 2007-03-01
ES2357626T3 (es) 2011-04-28
US8105585B2 (en) 2012-01-31
CN101297034A (zh) 2008-10-29
EP1917355B1 (de) 2010-12-08
WO2007024628A3 (en) 2007-06-14
ATE491026T1 (de) 2010-12-15
CA2620903A1 (en) 2007-03-01
EP1917355A4 (de) 2009-05-27
JP2009506033A (ja) 2009-02-12
EP1917355A2 (de) 2008-05-07

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